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Food Science and Human Wellness 2024年第5期13卷 2959-2969页

作者： Chenchen Yu Xinrong He Nairu Ji Shuai kang Dongxiao Li Huilin Zhang Yang Yang Dong lai Qingmei Liu Guangming Liu College of Ocean Food and Biological Engineering Xiamen Key Laboratory of Marine Functional FoodFujian Provincial Engineering Technology Research Center of Marine Functional FoodJimei UniversityXiamen 361021China The Second Affiliated Hospital of Xiamen Medical College Xiamen 361021China

In recent years,the allergy rate of oysters has surged,and daily food processing methods make it hard to reduce heat resistance and digestive allergy such as tropomyosin(TM).In this study,the Maillard reaction with xylose significantly reduced the IgE binding capacity of Alectryonella plicatula food matrix(AFM),that reduced by(77.81±2.68)%.The study found the Maillard reaction changes the structure of the AFM,in which the content ofα-helix decreased by(24.64±1.46)%.Structural transformation further explains why the Maillard reaction alters the immunobinding activity of *** addition,the Maillard reaction reduces the digestive stability of the AFM and makes TM in the *** food matrix Maillard reaction products(AFM-MRPs)more easily *** on the above research,10 amino acids on the 7 IgE epitopes of TM were *** result indicates that the Maillard reaction reduces the immunobinding activity of the AFM by changing the structure and modifying the amino acids on the epitope.

关键词： Alectryonella plicatula Food matrix Immunobinding activity Maillard reaction Tropomyosin

Simultaneously healing cracks and strengthening additively manufactured Co_(34)Cr_(32)Ni_(27)Al_(4)Ti_(3) high-entropy alloy by utilizing Fe-based metallic glasses as a glue

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Journal of Materials Science & Technology 2024年第12期179卷 125-137页

作者： Hao kang Kaikai Song Leilei Li Xiaoming Liu Yandong Jia Gang Wang Yaocen Wang Si Lan Xin Lin lai-Chang Zhang Chongde Cao School of Physical Science and Technology Northwestern Polytechnical UniversityXian 710072China School of Mechanical Electrical&Information EngineeringShandong UniversityWeihai 264209China Institute of Materials Shanghai UniversityShanghai 200444China Herbert Gleiter Institute of Nanoscience School of Materials Science and EngineeringNanjing University of Science and TechnologyNanjing 210094China State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXian 710072China Centre for Advanced Materials and Manufacturing School of EngineeringEdith Cowan University270 Joondalup DriveJoondalupPerthWestern Australia 6027Australia Research and Development Institute of Northwestern Polytechnical University in Shenzhen Shenzhen 518057China

Solidification cracking issues during additive manufacturing(AM)severely prevent the rapid development and broad application of this *** this work,a representative Co_(34)Cr_(32)Ni_(27)Al_(4)Ti_(3) high-entropy al-loy(HEA)susceptible to crack formation was fabricated by selective laser melting(SLM).As expected,many macroscopic cracks *** crack issues were successfully solved after introducing a certain amount of Fe-based metallic glass(MG)powder as a glue during *** effect of MG addition on the formation and distribution of defects in the SLM-processed HEA was quantitatively *** an increasing mass fraction of the MG,the dominant defects transformed from cracks to lack of fusion(LOF)defects and finally ***,the MG preferred to be segregated to the boundaries of the molten ***,the coarse columnar crystals gradually transformed into equiaxed crystals in the molten pool and fine-equiaxed crystals at the edge of the molten pool,inhibiting the initiation of cracks and providing extra grain boundary ***,multiple precipitates are formed at the boundaries of cellular structures,which contribute significantly to *** to the brit-tle SLM-processed Co_(34)Cr_(32)Ni_(27)Al_(4)Ti_(3) HEA,the SLM-processed HEA composite exhibited a high ultimate tensile strength greater than 1.4 Ga and enhanced *** work demonstrates that adding Fe-based MG powders as glues into SLM-processed HEAs may be an attractive method to heal cracks and simultaneously enhance the mechanical properties of additively manufactured products.

关键词： Selective laser melting High-entropy alloys Crack healing Metallic glasses Mechanical properties

Application of 3 dimension-printed injection-molded polyether ether ketone lunate prosthesis in the treatment of stage Ⅲ Kienböck’s disease: A case report

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World Journal of Clinical Cases 2022年第24期10卷 8761-8767页

作者： Cheng-Song Yuan Yao Tang Hai-Qiong Xie Tao-Tao Liang Hong-Tao Li kang-lai Tang Sports Medicine Center The First Affiliated Hospital of Army Medical UniversityChongqing 400038China

BACKGROUND Polyether ether ketone(PEEK)is a high-performance medical polymer,and there are some clinical cases of PEEK prosthesis ***,application of 3D-printed injection-molded PEEK lunate prosthesis for treatment of stage Ⅲ Kienböck’s disease has not been *** study’s purpose was to analyze the clinical efficacy of 3D-printed injection-molded PEEK lunate prosthesis in the treatment of stage Ⅲ Kienböck’s disease and thus provide a good therapeutic choice for Kienböck’s *** SUMMARY We report a patient with stage Ⅲ Kienböck’s *** the healthy lunate bone as reference,3D lunate reconstruction was performed using a mirroring technique.A PEEK lunate prosthesis was prepared by 3D printing and injection molding,and then it was inserted into the original anatomical position after removing the necrotic lunate *** pain and function,anatomical suitability of the lunate prosthesis,and complications were evaluated and analyzed *** the last visit(one year after surgery),the range of motion,grasp force,visual analog scale score and Cooney score of the affected wrist were significantly improved,and postoperative X-ray examination indicated that the lunate prosthesis had good anatomical suitability for adjacent bony *** The 3D-printed injection-molded PEEK lunate prosthesis demonstrated definite efficacy in treating stage Ⅲ Kienböck’s disease.

关键词： 3D printing Polyetheretherketone Kienböck disease Lunate fixation Lunate collapse Clinical outcomes Case report

Decaprenyl diphosphate synthase subunit 2 as a prognosis factor in hepatocellular carcinoma

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World Journal of Gastroenterology 2015年第10期21卷 3055-3065页

作者： Wei Huang Fei Gao kang Li Wen Wang Ya-Rou lai Shao-Hui Tang Dong-Hua Yang Department of Gastroenterology The First Affiliated Hospital of Jinan University Department of Gastroenterology Panyu Hexian Memorial Hospital

AIM:To investigate the involvement of decaprenyl diphosphate synthase subunit 2(PDSS2) in development and progression of human hepatocellular carcinoma(HCC).METHODS:PDSS2 protein expression was examined in well-and poorly differentiated HCC tumor *** levels of PDSS2 expression were compared with clinical features and prognosis of HCC *** effects of PDSS2 on cell proliferation,cell cycle,apoptosis,cell migration,and invasion in HCC Hep G2 cells were also ***:PDSS2 was downregulated in poorly differentiated cancer samples compared with welldifferentiated tumor samples,and the expression level was markedly lower in HCC tissues than in histologically normal tissue adjacent to the *** protein expression was negatively associated with the status of HCC *** addition,overexpression of PDSS2dramatically suppressed cell proliferation and colony formation,and induced apoptosis in Hep G2 cells by inducing G1-phase cell-cycle *** migration and invasion capabilities of Hep G2 cells were significantly decreased following PDSS2 ***:Decreased PDSS2 expression is an unfavorable prognostic factor for HCC,and PDSS2 has potent anticancer activity in HCC tissues and Hep G2cells.

关键词： Decaprenyl diphosphate synthase subunit 2 Hepatoce

Reusable Component Technology in the Development of Agile Supply Chain Management System

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厦门大学学报（自然科学版） 2002年第S1期41卷 264-265页

作者： lai Guo-ming, CHAI Yue-ting, HE kang-kang, LIU Yi (Department of Automation, Tsinghua University, Beijing 100084, China)

Agile Supply Chain Management (ASCM) is one of the ke y techniques, which support dynamic enterprise alliance and realize agile manufa cturing. But the optimal run of ASCS depends on a good-constructed Agile Supply Chain Management System (ASCMS), so that the materials flow, information flow a nd funding flow in the supply chain are used with high efficiency. The requireme nts of ASCMS are constantly changeable, which requires that ASCMS has dynamical reuse, integration and open interface. Reusable components theory is one of the most important directions of software engineering. It’s a feasible approach to solve software crisis and to increase software productivity and quality. ASCMS d eveloped with reusable components can easily be re-constructed, and has good op en interfaces. It will also sharply shorten the development life circle of syste m, and avoid unnecessary errors that result from the process of re-developing t hose components. In order to develop ASCMS based on reusable components quickly, the first thing we need to do is to construct the framework for ASCMS called system architecture . The framework referred in this context is not only a reference system of ASCMS , but also the operation system (including run-time library and communication p rotocols), which the ASCMS determined. So we can abstract logic units of the sys tem (they are the logic base of the ASCMS components), and the relationships amo ng them. And the operation system and communication protocols provide these comp onents with a running platform. Of course, the most important thing is to constr uct an abundant components depository. Components in the depository should h ave some properties such as: (1) Components should be built upon a specific oper ation system (e.g., windows) and standard communication protocols (e.g., IIOP in CORBA’s specification); (2)Self-containment, that shows it’s unnecessary to include other components when some component is reused since that component cont ains

关键词： supply chain ASCMS reusable component CORBA

Noninvasive evaluation of hepatic fibrosis in children with infant hepatitis syndrome

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World Journal of Gastroenterology 2006年第44期12卷 7155-7160页

作者： Zhi-Xian Li Yun He Ji Wu Bu-Lin Zhang Hong Yang Ling-Ling Wang Yun Ma kang-lai Wei Department of Ultrasound First Affiliated Hospital Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China Department of Pediatrics First Affiliated Hospital Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China Department of Pathology First Affiliated Hospital Guangxi Medical University Nanning 530021 Guangxi Zhuang Autonomous Region China

AIM： To elucidate the impact of hemodynamic parameters on ultrasonography and serum fibrosis markers for the assessment of liver fibrosis in the children with infant hepatitis syndrome （IHS）. METHODS： Forty-one children with IHS and 46 healthy infants were examined by ultrasonography, and several hemodynamic indices such as peak systolic velocity （PSV） and resistant index （RI） of proper hepatic artery （PHA） were measured. Serum fibrosis markers including hyaluronic acid （HA）, pre-collagen type-Ⅲ （PC-Ⅲ）, collagen type Ⅳ （C-Ⅳ）, and laminin （LN） were assayed by radioimmunoassays. In children with IHS, liver tissues were obtained either by ultrasound-guided liver biopsy （n = 35） or in the course of operation （n = 6）. The stages of hepatic fibrosis were scored as mild （S1 and S2）, moderate （S3）, or severe （S4） according to liver histological diagnosis. Multiple groups comparative and Spearman correlative analyses were carried out. RESULTS： Histopathologically, 39 children （95.1%） were found to have hepatic fibrosis, 12 of them stage Sl or S2, 12 stage S3, and 15 stage S4. PSV, RI of the PHA, and serum HA showed a consecutive increase from mild to severe hepatic fibrosis and a close positive correlation with hepatic fibrosis in IHS group （r = 0.717, 0.745 and 0.712, respectively, P = 0.001）. The Doppler waveform of HV was also positively correlated with the degree of hepatic fibrosis in IHS group （r = 0.783, P 〈 0.001）.CONCLUSION： Combination of ultrasonic studies on the hepatic hemodynamics with the evaluation of serum HA may provide an indicator for hepatic fibrosis in patients with IHS, This may be a useful noninvasive method for the diagnosis and evaluation of the prognosis of IHS.

关键词： Infant hepatitis syndrome Hepatic fibrosis Doppler ultrasonography Hemodynamics Hyaluronic acid

High mechanical strength Si anode synthesis with interlayer bonded expanded graphite structure for lithium-ion batteries

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Journal of Energy Chemistry 2024年第6期93卷 253-263,I0007页

作者： Wenhui lai Jong Hak Lee Lu Shi Yuqing Liu Yanhui Pu Yong kang Ong Carlos Limpo Ting Xiong Yifan Rao Chorng Haur Sow Barbaros Ozyilmaz Department of Material Science&Engineering National University of SingaporeSingapore 117575Singapore Center for Advanced 2D Materials National University of SingaporeSingapore 117546Singapore Department of Physics National University of SingaporeSingapore 117551Singapore Institute forFunctional Intelligent Materials National University of SingaporeSingapore 117544Singapore

Despite advancements in silicon-based anodes for high-capacity lithium-ion batteries,their widespread commercial adoption is still hindered by significant volume expansion during cycling,especially at high active mass loadings crucial for practical *** root of these challenges lies in the mechanical instability of the material,which subsequently leads to the structural failure of the ***,we present a novel synthesis of a composite combining expanded graphite and silicon *** composite features a unique interlayer-bonded graphite structure,achieved through the application of a modified spark plasma sintering ***,this innovative structure not only facilitates efficient ion and electron transport but also provides exceptional mechanical strength(Vickers hardness:up to658 MPa,Young's modulus:11.6 GPa).This strength effectively accommodates silicon expansion,resulting in an impressive areal capacity of 2.9 mA h cm^(-2)(736 mA h g^(-1)) and a steady cycle life(93% after 100cycles).Such outsta nding performance is paired with features appropriate for large-scale industrial production of silicon batteries,such as active mass loading of at least 3.9 mg cm^(-2),a high-tap density electrode material of 1.68 g cm^(-3)(secondary clusters:1.12 g cm^(-3)),and a production yield of up to 1 kg per day.

关键词： Lithium-ion battery Silicon anode Spark plasma sintering Interlayer bonding Mechanical strength Tap density

A GaN p-i-p-i-n Ultraviolet Avalanche Photodiode

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Chinese Physics Letters 2012年第9期29卷 193-195页

作者： ZHENG Ji-Yuan WANG lai HAO Zhi-Biao LUO Yi WANG Lan-Xi CHEN Xue-kang Tsinghua National Laboratory for Information Science and Technology State Key Laboratory on Integrated OptoelectronicsDepartment of Electronic EngineeringTsinghua UniversityBeijing 100084 Science and Technology on Surface Engineering Laboratory Lanzhou Institute of PhysicsLanzhou 730000

A separated absorption and multiplication GaN p–i–p–i–n avalanche photo-diode(APD)with a 25μm diameter mesa is proposed and *** to the conventional p–i–n APD,the p–i–p–i–n structure reduces the probability of premature micro-plasma breakdown,raises the gain from 30 to 400 and reduces the work voltage from 93 to 48 *** temperature test is set on p–i–p–i–n APDs,and the positive coefficient of 30 mV/K shows that avalanche breakdown happens in the *** peak responsivity of p–i–p–i–n APDs is 0.11 A/W under a wavelength of 358 nm.

关键词： breakdown GaN avalanche

Pediatric gastric cancer presenting with massive ascites

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World Journal of Gastroenterology 2015年第11期21卷 3409-3413页

作者： Chien-Heng Lin Wei-Ching Lin I-Hsiu lai Shu-Fen Wu kang-Hsi Wu An-Chyi Chen Department of Pediatrics Children’s HospitalChina Medical University Hospital College of Medicine School of MedicineChina Medical University Department of Radiology China Medical University Hospital College of Chinese Medicine School of Chinese MedicineChina Medical University

Gastric adenocarcinoma is quite rare in children and as a result very little experience has been reported on with regards to clinical presentation,treatment and *** describe the case of a 16-year-old boy presenting with abdominal fullness and poor appetite for 7 *** showed massive ascites and computed tomography imaging revealed the presence of gastric mucosa thickness with omentum *** diagnosis of gastric adenocarcinoma was biopsyproven *** gastric adenocarcinoma being quite rare in the pediatric patient population,we should not overlook the possibility of gastric adenocarcinoma when a child presents with distended abdomen and massive ascites.

关键词： Gastric adenocarcinoma Ascites Children

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基于单视点调节相机模型的水下图像三维重构

北京航空航天大学学报 2015年第11期41卷 2017-2022页

作者：魏迎梅康来国防科学技术大学信息系统与管理学院长沙410073 国防科学技术大学信息系统工程重点实验室长沙410073

水下图像成像过程中,每个场景点所对应的光线在传播过程中均经过多种折射率不同的介质,因此水下图像会产生折射变形,导致传统基于单视点相机模型的水下图像三维重构方法精度极大降低.在理论分析一个新的单视点调节模型对水下图像折射变... 详细信息

水下图像成像过程中,每个场景点所对应的光线在传播过程中均经过多种折射率不同的介质,因此水下图像会产生折射变形,导致传统基于单视点相机模型的水下图像三维重构方法精度极大降低.在理论分析一个新的单视点调节模型对水下图像折射变形的补偿能力的基础上,提出一种高效、自动的水下图像三维重构及其非线性优化方法.为了验证该方法的性能,利用合成数据和真实图像对其进行测试,并依据重构有效性、重构误差等定量指标考察分析了实验结果.实验结果表明,提出的多视图水下三维重构方法可有效补偿水下场景成像空间变形,进而显著提高传统基于单视点相机模型的水下三维重构质量.

关键词：水下图像三维重构折射变形单视点调节相机模型非线性优化空间变形