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The Journal of China Universities of Posts and Telecommunications 2021年第4期28卷 13-28页

作者： kang mancong Li Xi Ji Hong Zhang Heli School of Telecommunication Engineering Beijing University of Posts and TelecommunicationsBeijing 100876China

Predicting user states in future and rendering visual feedbacks accordingly can effectively reduce the visual experienced delay in the tactile Internet(TI). However, most works omit the fact that different parts in an image may have distinct prediction requirements, based on which different prediction models can be used in the predicting process, and then it can further improve predicting quality especially under resources-limited environment. In this paper, a hybrid prediction scheme is proposed for the visual feedbacks in a typical TI scenario with mixed visuo-haptic interactions, in which haptic traffic needs sufficient wireless resources to meet its stringent communication requirement, leaving less radio resources for the visual feedback. First, the minimum required number of radio resources for haptic traffic is derived based on the haptic communication requirements, and wireless resources are allocated to the haptic and visual traffics afterwards. Then, a grouping strategy is designed based on the deep neural network(DNN) to allocate different parts from an image feedback into two groups to use different prediction models, which jointly considers the prediction deviation thresholds, latency and reliability requirements, and the bit sizes of different image parts. Simulations show that, the hybrid prediction scheme can further reduce the visual experienced delay under haptic traffic requirements compared with existing strategies.

关键词： tactile Internet ultra-reliable and low-latency communications enhanced mobile broadband visuo-haptic feedbacks layered rendering

Distributed Edge Cooperation and Data Collection for Digital Twins of Wide-Areas

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China Communications 2023年第8期20卷 177-197页

作者： mancong kang Xi Li Hong Ji Heli Zhang Key Laboratory of Universal Wireless Communications Beijing University of Posts and TelecommunicationsBeijing 100876China

Digital twins for wide-areas(DT-WA)can model and predict the physical world with high fidelity by incorporating an artificial intelligence(AI)***,the AI model requires an energy-consuming updating process to keep pace with the dynamic environment,where studies are still in *** reduce the updating energy,this paper proposes a distributed edge cooperation and data collection *** AI model is partitioned into multiple sub-models deployed on different edge servers(ESs)co-located with access points across wide-area,to update distributively using local sensor *** reduce the updating energy,ESs can choose to become either updating helpers or recipients of their neighboring ESs,based on sensor quantities and basic updating *** would share their updated sub-model parameters with neighboring recipients,so as to reduce the latter updating *** minimize system energy under updating convergency and latency constraints,we further propose an algorithm to let ESs distributively optimize their cooperation identities,collect sensor data,and allocate wireless and computing *** comprises several constraint-release approaches,where two child optimization problems are solved,and designs a largescale multi-agent deep reinforcement learning *** shows that the proposed scheme can efficiently reduce updating energy compared with the baselines.

关键词： digital twin smart city multi-agent deep reinforcement learning resource allocation

智能物联网技术赋能算网一体数据库的效能优化

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计算机研究与发展 2024年第11期61卷 3835-3845页

作者：朱茂盛王宝晗康曼聪于巍杨利超中移(苏州)软件技术有限公司江苏苏州215009 中国移动有限公司研究院北京100053 苏州大学苏州医学院公共卫生学院江苏苏州215000

海量感知数据的采集、存储和共享技术推动了物联网的兴起,其大规模应用对数据库系统提出了数据强一致和资源高效能的迫切要求.然而,现有的数据库系统架构和管控方法在保证一致性的约束下,较多采用降低传输数据量和增加节点存储副本的方... 详细信息

海量感知数据的采集、存储和共享技术推动了物联网的兴起,其大规模应用对数据库系统提出了数据强一致和资源高效能的迫切要求.然而,现有的数据库系统架构和管控方法在保证一致性的约束下,较多采用降低传输数据量和增加节点存储副本的方式降低通信成本,缺少对系统网络资源的一体化感知和优化,从而导致数据库效能低下.为此,构建算网一体数据库系统,驱动算力资源和网络的一体化感知表征,并将智能物联网(artificial intelligence of things,AIoT)技术赋能数据库,实现算力资源和网络的联合智能调度,以降低综合成本和提升算网效能.首先,构建算网一体的分布式数据库网络,并分析其架构特点.然后,为实现计算和通信优化变量的统一表征,构建了一体化代价感知模型.并在此基础上提出了智能化的一站式资源优化算法,满足一致性时延约束的前提下,最优化数据库系统的整体算网效能.最后,仿真实验验证了所提架构和算法在算网性能、算法收敛、集成代价和资源效率上均具有优越性.

关键词：智能物联网算网一体分布式数据库一体感知效能优化

The autophagy-lysosome pathway:a potential target in the chemical and gene therapeutic strategies for Parkinson’s disease

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Neural Regeneration Research 2025年第1期20卷 139-158页

作者： Fengjuan Jiao Lingyan Meng kang Du Xuezhi Li School of Mental Health Jining Medical UniversityJiningShandong ProvinceChina Shandong Collaborative Innovation Center for Diagnosis Treatment and Behavioral Interventions of Mental DisordersInstitute of Mental HealthJining Medical UniversityJiningShandong ProvinceChina

Parkinson’s disease is a common neurodegenerative disease with movement disorders associated with the intracytoplasmic deposition of aggregate proteins such asα-synuclein in *** one of the major intracellular degradation pathways,the autophagy-lysosome pathway plays an important role in eliminating these *** evidence has shown that upregulation of the autophagy-lysosome pathway may contribute to the clearance ofα-synuclein aggregates and protect against degeneration of dopaminergic neurons in Parkinson’s ***,multiple genes associated with the pathogenesis of Parkinson’s disease are intimately linked to alterations in the autophagy-lysosome ***,this pathway appears to be a promising therapeutic target for treatment of Parkinson’s *** this review,we briefly introduce the machinery of ***,we provide a description of the effects of Parkinson’s disease–related genes on the autophagy-lysosome ***,we highlight the potential chemical and genetic therapeutic strategies targeting the autophagy–lysosome pathway and their applications in Parkinson’s disease.

关键词： autophagy chemical therapy gene therapy Parkinson’s disease α-synuclein

Investigating Müller glia reprogramming in mice: a retrospective of the last decade, and a look to the future

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Neural Regeneration Research 2025年第4期20卷 946-959页

作者： Zhiyuan Yin Jiahui kang Xuan Cheng Hui Gao Shujia Huo Haiwei Xu Key Lab of Visual Damage and Regeneration&Restoration of Chongqing Southwest Eye HospitalSouthwest HospitalThird Military Medical University(Army Medical University)ChongqingChina

Müller glia,as prominent glial cells within the retina,plays a significant role in maintaining retinal homeostasis in both healthy and diseased *** lower vertebrates like zebrafish,these cells assume responsibility for spontaneous retinal regeneration,wherein endogenous Müller glia undergo proliferation,transform into Müller glia-derived progenitor cells,and subsequently regenerate the entire retina with restored ***,Müller glia in the mouse and human retina exhibit limited neural reprogramming.Müller glia reprogramming is thus a promising strategy for treating neurodegenerative ocular disorders.Müller glia reprogramming in mice has been accomplished with remarkable success,through various *** in molecular,genetic,epigenetic,morphological,and physiological evaluations have made it easier to document and investigate the Müller glia programming process in ***,there remain issues that hinder improving reprogramming efficiency and ***,understanding the reprogramming mechanism is crucial toward exploring factors that will improve Müller glia reprogramming efficiency,and for developing novel Müller glia reprogramming *** review describes recent progress in relatively successful Müller glia reprogramming *** also provides a basis for developing new Müller glia reprogramming strategies in mice,including epigenetic remodeling,metabolic modulation,immune regulation,chemical small-molecules regulation,extracellular matrix remodeling,and cell-cell fusion,to achieve Müller glia reprogramming in mice.

关键词： cell fusion chemical small-molecules epigenetic extracellular matrix immune metabolic mice Müller glia neurodegenerative diseases reprogramming retina regeneration

Potential role of tanycyte-derived neurogenesis in Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1599-1612页

作者： Guibo Qi Han Tang Jianian Hu Siying kang Song Qin Department of Anatomy Histologyand EmbryologySchool of Basic Medical SciencesFudan UniversityShanghaiChina State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghaiChina

Tanycytes, specialized ependymal cells located in the hypothalamus, play a crucial role in the generation of new neurons that contribute to the neural circuits responsible for regulating the systemic energy balance. The precise coordination of the gene networks controlling neurogenesis in naive and mature tanycytes is essential for maintaining homeostasis in adulthood. However, our understanding of the molecular mechanisms and signaling pathways that govern the proliferation and differentiation of tanycytes into neurons remains limited. This article aims to review the recent advancements in research into the mechanisms and functions of tanycyte-derived neurogenesis. Studies employing lineage-tracing techniques have revealed that the neurogenesis specifically originating from tanycytes in the hypothalamus has a compensatory role in neuronal loss and helps maintain energy homeostasis during metabolic diseases. Intriguingly,metabolic disorders are considered early biomarkers of Alzheimer's disease. Furthermore,the neurogenic potential of tanycytes and the state of newborn neurons derived from tanycytes heavily depend on the maintenance of mild microenvironments, which may be disrupted in Alzheimer's disease due to the impaired blood–brain barrier ***, the specific alterations and regulatory mechanisms governing tanycyte-derived neurogenesis in Alzheimer's disease remain unclear. Accumulating evidence suggests that tanycyte-derived neurogenesis might be impaired in Alzheimer's disease, exacerbating neurodegeneration. Confirming this hypothesis, however, poses a challenge because of the lack of long-term tracing and nucleus-specific analyses of newborn neurons in the hypothalamus of patients with Alzheimer's disease. Further research into the molecular mechanisms underlying tanycyte-derived neurogenesis holds promise for identifying small molecules capable of restoring tanycyte proliferation in neurodegenerative diseases. This line of investigation could pro

关键词： Alzheimer's disease blood–brain barrier ependymoglial cells hypothalamus metabolic diseases neural stem cells neurogenesis neuroinflammatory diseases neurons tanycyte

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6G数字孪生网络分布式架构及关键技术

信息通信技术 2024年第2期18卷 19-25页

作者：丁海煜朱艳宏郑青碧邓娟康曼聪中国移动有限公司研究院北京100053 中关村泛联院移动通信技术创新应用研究院北京100088 北京邮电大学北京100876

面对新一轮科技与产业变革,新型信息领域创新性技术正在不断脱颖而出,以数字孪生等为代表的新型技术正在为6G网络的发展打开新的格局。数字孪生作为支撑网络统一规划、编排和管理的发展范式,是赋能6G演进的重要技术方向。文章深入分析... 详细信息

面对新一轮科技与产业变革,新型信息领域创新性技术正在不断脱颖而出,以数字孪生等为代表的新型技术正在为6G网络的发展打开新的格局。数字孪生作为支撑网络统一规划、编排和管理的发展范式,是赋能6G演进的重要技术方向。文章深入分析数字孪生网络的现状和发展态势,提出面向6G的数字孪生网络分布式架构体系,并针对数据、建模和编排预验证三大核心技术进行详细研究,提出创新性的解决方案,可有效应对数字孪生网络面临的关键挑战。

关键词： 6G 数字孪生网络高阶建模双闭环编排仿真验证

Photo‑Energized MoS_(2)/CNT Cathode for High‑Performance Li–CO_(2)Batteries in a Wide‑Temperature Range

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Nano-Micro Letters 2025年第1期17卷 160-175页

作者： Tingsong Hu Wenyi Lian kang Hu Qiuju Li Xueliang Cui Tengyu Yao Laifa Shen Jiangsu Key Laboratory of Materials and Technologies for Energy Storage College of Materials Science and TechnologyNanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Li–CO_(2) batteries are considered promising energy storage systems in extreme environments such as Mars;however,severe performance degradation will occur at a subzero temperature owning to the sluggish reaction ***,a photo-energized strategy adopting sustainable solar energy in wide working temperature range Li–CO_(2) battery was achieved with a binder-free MoS_(2)/carbon nanotube(CNT)photo-electrode as *** unique layered structure and excellent photoelectric properties of MoS_(2) facilitate the abundant generation and rapid transfer of photo-excited carriers,which accelerate the CO_(2) reduction and Li_(2)CO_(3) decomposition upon *** illuminated battery at room temperature exhibited high discharge voltage of 2.95 V and mitigated charge voltage of 3.27 V,attaining superior energy efficiency of 90.2%and excellent cycling stability of over 120 *** at an extremely low temperature of−30℃,the battery with same electrolyte can still deliver a small polarization of 0.45 V by the photoelectric and photothermal synergistic mechanism of MoS_(2)/CNT *** work demonstrates the promising potential of the photo-energized wide working temperature range Li–CO_(2) battery in addressing the obstacle of charge overpotential and energy efficiency.

关键词： Li-CO_(2)batteries Photo-energized Wide operation-temperature Kinetics MoS_(2)

Experimental Study on Energy Storage Characteristics of Sintered Ore Particle Packed Beds

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Journal of Thermal Science 2025年第1期34卷 242-253页

作者： LAI Zhenya DING Liwei LYU Hongkun HOU Chenglong CHEN Jiaying GUO Xutao HAN Gaoyan ZHANG kang State Grid Zhejiang Electric Power Research Institute State Key Laboratory of Clean Energy Utilization Zhejiang University

The particle packed bed energy storage system has advantages such as low costs and wide temperature ranges,which can be combined with solar thermal power generation systems to solve the inherent volatility and discontinuity of renewable *** new materials with low costs and excellent storage performances is one of the eternal research hotspots in the field of energy *** paper innovatively uses sintered ore particles as energy storage material and studies the effect of particle size on the airflow resistance characteristics,energy storage characteristics,and thermocline evolution characteristics of the packed bed through thermal energy storage *** results indicate that for the particles in the macro scale,the smaller the particle,the lower the absolute permeability of the bed and the greater the airflow *** packed bed with smaller particles has a larger specific surface area,larger bulk mass,and smaller bed ***,the packed beds with smaller particles have better thermocline characteristics,less irreversible loss,and can achieve higher thermal efficiency and higher exergy efficiency in the heat storage *** cycle thermal efficiency in packed beds with 25-40 mm,16-25 mm,and 10-16 mm particles is 53.58%,56.27%,and 57.60%,respectively,and the cycle exergy efficiency is 61.81%,69.25%,and 74.13%,***,this paper also studies the effect of discharging airflow rates on thermal storage *** experimental results indicate that suitable discharging strategies should be selected based on different heat demands.

关键词： airflow resistance particle packed bed thermal energy storage thermocline evolution

Non-existence of Shimura curves of Mumford type generically in the non-hyperelliptic locus

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Science China Mathematics 2025年

作者： Xin Lü Shengli Tan kang Zuo School of Mathematical Sciences Key Laboratory of Mathematics and Engineering Applications(Ministry of Education) Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal University School of Mathematics and Statistics Wuhan University Institut für Mathematik Universit?t Mainz

We show that there does not exist any Shimura curve with a strictly maximal Higgs field generically in the Torelli locus of non-hyperelliptic curves of genus g≥4. In particular, Shimura curves of Mumford type are not...

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