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Applications of dynamical complexity theory in traditional Chinese medicine

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Frontiers of Medicine 2014年第3期8卷 279-284页

作者： Yan Mal Shuchen Sun Chung-kang Peng Division of Interdisciplinary Medicine and Biotechnology Beth Israel Deaconess Medical Centel Harvard Medical School Boston MA 02215USA Sleep CenteR Eye Hospital China Academy of Chinese Medical Sciences Beijing 100040 China Department of Otolaryngology Guang 'anmen Hospital China Academy of Chinese Medical Sciences Beijing 100053 China Center for Dynamical Biomarkers and Translational Medicine National Central University Chung-Li Taiwan China

Traditional Chinese medicine （TCM） has been gradually accepted by the world. Despite its widespread use in clinical settings, a major challenge in TCM is to study it scientifically. This difficulty arises from the fact that TCM views human body as a complex dynamical system, and focuses on the balance of the human body, both internally and with its external environment. As a result, conventional tools that are based on reductionist approach arc not adequate. Methods that can quantify the dynamics of complex integrative systems may bring new insights and utilities about the clinical practice and evaluation of efficacy of TCM. The dynamical complexity theory recently proposed and its computational algorithm, Multiscale Entropy （MSE） analysis, are consistent with TCM concepts. This new system level analysis has been successfully applied to many health and disease related topics in medicine. We believe that there could be many promising applications of this dynamical complexity concept in TCM. In this article, we propose some promising applications and research areas that TCM practitioners and researchers can pursue.

关键词： traditional Chinese medicine Multiscale Entropy dynamical complexity system level applications

利用DQCT实现2018年8月超历史极值暴雨的高质量模拟

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兰州大学学报（自然科学版） 2024年第1期60卷 31-39页

作者：李博李帅康陈超钟水新华灯鑫徐波西安理工大学机械与精密仪器工程学院西安710048 中国气象局广州热带海洋气象研究所广东省区域数值天气预报重点实验室广州510080 广东省气象台广州510062 西安市气象局西安710016

构建较全面的双级质量控制技术(DQCT).利用中尺度天气预报模式(WRF)对2018年8月下旬华南地区一次超历史极值的暴雨过程进行高分辨率数值模拟,并用DQCT评判暴雨的模拟效果.结果表明,在暴雨形势背景场中用WRF成功模拟大尺度季风风场、西... 详细信息

构建较全面的双级质量控制技术(DQCT).利用中尺度天气预报模式(WRF)对2018年8月下旬华南地区一次超历史极值的暴雨过程进行高分辨率数值模拟,并用DQCT评判暴雨的模拟效果.结果表明,在暴雨形势背景场中用WRF成功模拟大尺度季风风场、西南暖湿气流与低压交汇过程,并准确复制了造成高潭镇极端降雨的中尺度对流系统.总降雨量中的中γ尺度极值暴雨中心模拟得较为准确.该模式在24 h降雨量模拟中成功复制了暴雨中心的演变过程;在6 h降雨量模拟中较好地再现了中γ尺度雨带的演变过程.在暴雨重灾区高潭镇1 h降雨量演变过程的模拟中,总体降雨趋势与实况吻合较好.定性分析结果同步得到定量指标的验证.

关键词：超历史极值暴雨中γ尺度雨带数值模拟双级质量控制技术

淀粉脂质复合体的构建及其Pickering乳液性能表征

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粮食与油脂 2024年第6期37卷 28-33页

作者：张灿高玲玲何梦影张康逸河南省农业科学院农副产品加工研究中心河南郑州450002 河南省全谷物小麦制品加工国际联合实验室河南郑州450002 河南省全谷物鲜食加工工程技术研究中心河南郑州450002

采用干法制备月桂酸、单月桂酸甘油酯、硬脂酸、单硬脂酸甘油酯的淀粉脂质复合体,并通过复合率、溶解率、膨胀力、碘吸收曲线、红外光谱、拉曼光谱、乳化性等对淀粉脂质复合体的性能进行表征。结果表明:4种淀粉脂质复合体的复合率随着... 详细信息

采用干法制备月桂酸、单月桂酸甘油酯、硬脂酸、单硬脂酸甘油酯的淀粉脂质复合体,并通过复合率、溶解率、膨胀力、碘吸收曲线、红外光谱、拉曼光谱、乳化性等对淀粉脂质复合体的性能进行表征。结果表明:4种淀粉脂质复合体的复合率随着脂肪酸碳链的增长而增大;溶解率和膨胀力总体上随着温度的升高逐渐变大,但随着碳原子数的增加而减小。碘吸收特性、红外光谱和拉曼光谱结果表明,随着碳原子数的增多,V型结晶淀粉与脂肪酸复合的效果越好。此外,利用质量浓度为8 g/L的淀粉脂质复合体制备的乳液具有较稳定的乳化状态。试验表明,淀粉脂质复合体在Pickering乳液中具有较大的应用潜力。

关键词：淀粉淀粉脂质复合体乳化性 Pickering乳液

达芬奇机器人应用于军事飞行员甲状腺癌治疗1例

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空军航空医学 2024年第3期41卷 286-287页

作者：宋媛媛康阳祝玉慧解放军第九六〇医院特勤科济南250000 解放军71901部队卫生连解放军第九六〇医院干部病房济南250000

1病例资料男,38岁,直-19飞行员,飞行时间3000 h。2021年12月于解放军第九六〇医院体检发现甲状腺右侧一绿豆大小肿物,质硬,表面光滑,无触痛,无自觉症状,可随吞咽上、下活动,未触及周围肿大淋巴结。甲状腺左侧未触及异常肿块。B超示甲状... 详细信息

1病例资料男,38岁,直-19飞行员,飞行时间3000 h。2021年12月于解放军第九六〇医院体检发现甲状腺右侧一绿豆大小肿物,质硬,表面光滑,无触痛,无自觉症状,可随吞咽上、下活动,未触及周围肿大淋巴结。甲状腺左侧未触及异常肿块。B超示甲状腺右侧叶低回声结节,边界不清,可探及沙砾样钙化,颈部双侧淋巴结可见。遂全麻下行达芬奇机器人甲状腺右叶切除术,将右叶甲状腺并峡部全部切除,清扫右颈部中央区淋巴结。

关键词：甲状腺肿物体格检查合格鉴定达芬奇机器人飞行员

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光纤环网通信技术在减摇鳍控制系统中的应用

机电设备 2024年第4期41卷 97-100页

作者：胡彬康义星严凤祥上海船舶设备研究所上海200031

主要介绍了光纤环网通信技术在减摇鳍控制系统中的应用,提出一套基于光纤环网连接,多控制器冗余设计为核心的减摇鳍控制系统,介绍控制系统组成、交换机参数设置等,着重介绍Modbus TCP I/O主从站参数设置、软件设计方法以及通过S7通信设... 详细信息

主要介绍了光纤环网通信技术在减摇鳍控制系统中的应用,提出一套基于光纤环网连接,多控制器冗余设计为核心的减摇鳍控制系统,介绍控制系统组成、交换机参数设置等,着重介绍Modbus TCP I/O主从站参数设置、软件设计方法以及通过S7通信设计实现中央处理器(CPU)之间数据交换等,为提高减摇鳍控制系统的可靠性提供一条新途径。

关键词：减摇鳍光纤环网通信冗余

Exclusive enteral nutrition versus corticosteroids for treatment of pediatric Crohn's disease: a meta-analysis

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World Journal of Pediatrics 2019年第1期15卷 26-36页

作者： Yu Yu kang-Chen Chen Jie Chen Department of Gastroenterology Children's HospitalZhejiang University School of Medicine3333 Binsheng RoadBinjiang DistrictHangzhou 310051China First Affiliated Hospital Zhejiang University School of Medicine79 Qingchun RoadShangcheng DistrictHangzhou 310002China

Background Many studies have examined the effects of exclusive enteral nutrition (EEN) in children with Crohn's disease (CD),but corticosteroids are considered a superior therapy and are frequently used in *** meta-analysis aims to compare the efficacy of EEN with corticosteroids in treating pediatric *** A comprehensive retrieval from medical databases,including PubMed,EMBASE,MEDLINE,Web of Science,Wanfang data,VIP and CNKI,was performed using the search terms 'diet therapy','exclusive enteral nutrition','Crohn's disease','inflammatory bowel diseases','child' and 'pediatrics' from January 1990 to April *** We included 18 studies from 1329 identified sources in this *** was as effective as corticosteroids in inducing remission rate of children suffering from CD (OR =1.35;95% CI 0.90,2.10;P =0.14).Nevertheless,patients who received EEN were more likely to achieve both endoscopic mucosal healing (OR =5.24;95% CI 2.06,13.37;P =0.0005)and histological mucosal healing (OR =4.78;95% CI 1.89,12.08;P=0.0009) than those who received corticosteroids;the Pediatric Crohn's Disease Activity Index was lower [mean difference (MD)=-3.67;95% CI-4.91,-2.43] and weight gain was higher (MD=1.92;95% CI 0.02,3.83;P=0.05) in those patients who received EEN than in those who received *** difference was found in relapse rate (OR =0.57;95% CI 0.25,1.29;P=0.18),height for age or body mass index between the patients treated with EEN and corticosteroids at the 1-year end *** This meta-analysis reveals that there is no significant difference between EEN and corticosteroids in the efficacy of inducing remission rate of CD in a pediatric population,but EEN is superior to corticosteroids in improving short-term mucosal inflammation and reducing the PCDAI index.

关键词： Children Corticosteroids Crohn's disease Exclusive enteral nutrition Inflammatory bowel disease Nutrition

Surface Temperature Change of U75V 60 kg/m Heavy Rail During Heat Treatment

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Journal of Iron and Steel Research International 2013年第2期20卷 33-37,67页

作者： kang Hao WU Di ZHAO Xian-ming State Key Laboratory of Rolling and Automation Northeastern University

The U75V 60 kg/m heavy rail samples were heated to 900 ℃ in a resistance furnace for a fixed duration of 50 min. Under this condition, the samples were austenitized totally. Then, the samples were dragged out of furnace and cooled for 25 s in the open air. After that, the samples entered into the air spraying channel, and were cooled from the top and both sides by compressed air. During this period, main technical parameters were changed such as the distance between spray nozzles and surface of rail head, air pressure, air spraying time and air temperature. So under laboratory condition, optimal heat-treating parameters of U75V 60 kg/m heavy rail were determined as the distance between spray nozzles and surface of rail head of 15 mm, air pressure of 0.26 MPa, cooling time of 80 s, and air temperature of 28 ℃. The surface temperature at different positions of heavy rail was measured before and after heat treatment, and the temperature changing law was determined. The self tempering occurred on the surface of rail head after heat treatment, and the tempering temperature became the largest （about 3 min） after heat treatment, separately 528, 524 and 536 ℃ at the center, top fillet and bottom fillet of rail head. The heavy rail was cooled in open air after heat treatment; during this period, the temperature gap on the surface of heavy rail became smaller and smaller, and was reduced to zero when being cooled for 20 min.

关键词： temperature change heavy rail heat treatment

Erratum to"HLA-E-restricted Hantaan virus-specific CD8^(+)T cell responses enhance the control of infection in hemorrhagic fever with renal syndrome"[*** 5(2023)289-299]

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Biosafety and Health 2024年第1期6卷 59-59页

作者： kang Tang Yusi Zhang Xinyu Li Chunmei Zhang Xiaozhou Jia Haifeng Hu Lihua Chen Ran Zhuang Yun Zhang Boquan Jin Ying Ma Department of Immunology The Fourth Military Medical UniversityXi'an 710032China Eighth Hospital of Xi'an Xi'an 710061China Department of Infectious Diseases Tangdu HospitaThe Fourth Military Medical UniversityXi'an 710038China

The publisher regrets that during proofreading of the figure legend of Fig.6,the P value was misspelled in the sentence"while"n.s."indicates no significant difference P0.05)".

关键词： while restricted proof

粉防己地上部分化学成分及其潜在作用靶点及活性研究

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中成药 2024年第9期46卷 2980-2986页

作者：薛佳芸郭弯康云黄建明汪亚勤复旦大学药学院上海201203

目的研究粉防己Stephania tetrandra ***地上部分的化学成分并预测其潜在作用靶点和活性。方法粉防己地上部分70%乙醇提取物采用大孔树脂、硅胶、Sephadex LH-20、半制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构... 详细信息

目的研究粉防己Stephania tetrandra ***地上部分的化学成分并预测其潜在作用靶点和活性。方法粉防己地上部分70%乙醇提取物采用大孔树脂、硅胶、Sephadex LH-20、半制备HPLC进行分离纯化,根据理化性质及波谱数据鉴定所得化合物的结构。利用PharmMapper平台预测化合物的潜在作用靶点及活性。结果从中分离得到11个化合物,分别鉴定为6 S,6a S-N-neolitsine N_(α)-oxide(1)、新木姜子素(2)、荷包牡丹碱(3)、南天宁碱(4)、氧化南天宁碱(5)、oxophoebine(6)、N-乙酰去甲荷包牡丹碱(7)、鹅掌楸碱(8)、6 R,6a S-N-nantenine N_(β)-oxide(9)、氧化克班宁(10)、stigmast-4-ene-6β-ol-3-one(11)。化合物的潜在靶点包括胰腺素样生长因子1受体和转甲状腺素蛋白。结论化合物1为新化合物,化合物6、8~11为首次从该植物中分离得到。化合物1~11具有抑制多种肿瘤细胞的潜在活性。

关键词：粉防己地上部分化学成分分离鉴定作用靶点 PharmMapper