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Marine Life Science & Technology 2021年第3期3卷 347-354页

作者： Muddula Krishna Naranji Govinda Rao Velamala kandula sujatha Department of Marine Living Resources College of Science and TechnologyAndhra UniversityVisakhapatnam530003Andhra PradeshIndia Department of Zoology and Aquaculture College of Science and TechnologyRajamahendravaram533296Andhra PradeshIndia

We examined the reproductive biology of sawcheek scorpionfish,Brachypterois serrulata,collected from Visakhapatnam fish landing center(fishing area covered 16.98°-20.20°N,82.19°-86.53°E).We studied the annual reproductive cycle,fecundity,size at first maturity,mode of spawning with periodical changes and histological *** distribution and size at sexual maturity were calculated as 108 mm TL for *** mean gonado somatic index values of female increased rapidly from January to December,and reached its peak during January and *** fecundity of the fish species is determined by the size and weight of the *** fecundity varied from 1896 to 20,488,with an average of 5721.90 ova.

关键词： Brachypterois serrulata Central-Eastern Coast of India Fecundity GSI Length at first maturity

On the Existence of Subharmonic Screech in Choked Circular Jets from a Sharp-Edged Orifice

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Open Journal of Acoustics 2014年第1期4卷 20-25页

作者： Max kandula ESC-Team QNA NASA Kennedy Space Center USA

Experiments are performed in choked circular hot and cold nitrogen jets issuing from a 2.44 cm diameter sharp-edged orifice at a fully expanded jet Mach number of 1.85 in an effort to investigate the character of screech phenomenon. The stagnation temperature of the cold and the hot jets are 299 K and 319 K respectively. The axial distribution of the centerline Mach number was obtained with a pitot tube, while the screech data (frequency and amplitude) at different axial and radial stations were measured with the aid of microphones. The fundamental screech frequency of the hot jet is slightly increased relative to that of the cold jet. It is concluded that temperature effects on the screech amplitude are manifested with regard to the fundamental and the subharmonic even at relatively small temperature range considered.

关键词： Subharmonic Screech Sharp-Edged Orifice Circular Jets Thermal Effects

A benchtop brain injury model using resected donor tissue from patients with Chiari malformation

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Neural Regeneration Research 2023年第5期18卷 1057-1061页

作者： Jacqueline A.Tickle Jon Sen Christopher Adams David N.Furness Rupert Price Viswapathi kandula Nikolaos Tzerakis Divya M.Chari Aston Pharmacy School College of Health and Life SciencesAston UniversityBirminghamUK School of Medicine Faculty of Medicine and Health SciencesKeele UniversityStaffordshireUK School of Life Sciences Keele UniversityStaffordshireUK Department of Neurosurgery Royal Stoke University HospitalStoke-on-TrentUK

The use of live animal models for testing new therapies for brain and spinal cord repair is a controversial area. Live animal models have associated ethical issues and scientific concerns regarding the predictability of human responses. Alternative models that replicate the 3 D architecture of the central nervous system have prompted the development of organotypic neural injury models. However, the lack of reliable means to access normal human neural tissue has driven reliance on pathological or post-mortem tissue which limits their biological utility. We have established a protocol to use donor cerebellar tonsillar tissue surgically resected from patients with Chiari malformation(cerebellar herniation towards the foramen magnum, with ectopic rather than diseased tissue) to develop an in vitro organotypic model of traumatic brain injury. Viable tissue was maintained for approximately 2 weeks with all the major neural cell types detected. Traumatic injuries could be introduced into the slices with some cardinal features of post-injury pathology evident. Biomaterial placement was also feasible within the in vitro lesions. Accordingly, this ‘proof-of-concept’ study demonstrates that the model offers potential as an alternative to the use of animal tissue for preclinical testing in neural tissue engineering. To our knowledge, this is the first demonstration that donor tissue from patients with Chiari malformation can be used to develop a benchtop model of traumatic brain injury. However, significant challenges in relation to the clinical availability of tissue were encountered, and we discuss logistical issues that must be considered for model scale-up.

关键词： biomaterial Chiari malformation cerebellar slice human tissue injury model neuroregeneration organotypic traumatic brain injury

Areal Extent of Erosion and Accretion in and around the Gahirmatha Coast, NW of Bay of Bengal by Remote Sensing and GIS Analysis of Multi-Temporal Satellite Imagery

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International Journal of Geosciences 2015年第7期6卷 705-719页

作者： Balabathina Veeraanarayanaa kandula Ravikumar Talluri Ramesh Mopada Venkateswararao Pattam N. Sridhar P.I SYS-SERC Department of Science & Technology New Delhi India Department of Geology Andhra University Waltair India Department of Geography Andhra University Waltair India National Remote Sensing Agency Department of Space ISRO Hyderabad India

The shoreline morphology change due to erosion and deposition is a major concern for coastal zone management. In the present study, a highly dynamic coast of Gahirmatha on Bay of Bengal? in northeast India is experiencing active erosion, which is mainly wave and tide erosion related hazard threat ending human habitation and sustainability of the coast. In our study, high resolution satellite imagery of time series provided detailed sequence of coastal morphology and their changes in all respects. Comparison study of relative shoreline positions on time series satellite data spanning?three decades from 1973 to 2004 covering for the years of 1973, 1983, 1987, 1990, 1998, 2000 and 2004, provided regional changes with accelerated erosion and accretion. The result of the studies?have revealed that the areas of severe erosion found along the coast are confined to the promontories of the present day mouths itself of the Baitrani at Dhamra and Brahmani at Maipura inlets. In this background, it is significant to understand the magnitude of factors that are responsible for prograding or retrograding of coast. The present study is an attempt in this direction.

关键词： Accretion Erosion Morphology Coast Temporal Satellite Data

Is there a difference between 19G core biopsy needle and 22G core biopsy needle in diagnosing the correct etiology?——A meta-analysis and systematic review

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World Journal of Meta-Analysis 2017年第2期5卷 54-62页

作者： Manasa kandula Matthew L Bechtold Kaninika Verma Bhagat S Aulakh Deepak Taneja Srinivas R Puli Division of Internal Medicine University of Illinois College of Medicine at Peoria Division of Gastroenterology and Hepa-tology University of Missouri School of Medicine at Columbia Illinois Lung and Critical Care Institute University of Illinois College of Medicine at Peoria Division of Gastroenterology and Hepatology University of Illinois College of Medicine at Peoria

AIM To compare the accuracy of endoscopic ultra-sonography(EUS) 19 G core biopsies and 22 G core biopsies in diagnosing the correct etiology for a solid *** Articles were searched in Medline, Pub Med, and Ovid journals. Pooling was conducted by both fixed and random effects models. RESULTS Initial search identified 4460 reference articles for 19 G and 22 G, of these 670 relevant articles were selected and reviewed. Data was extracted from 6 studies for 19G(n = 289) and 16 studies for 22G(n = 592) which met the inclusion criteria. EUS 19 G core biopsies had a pooled sensitivity of 91.6%(95%CI: 87.1-95.0) and pooled specificity of 95.9%(95%CI: 88.6-99.2), whereas EUS 22 G had a pooled sensitivity of 83.3%(95%CI: 79.7-86.6) and pooled specificity of 64.3%(95%CI: 54.7-73.1). The positive likelihood ratio of EUS 19 G core biopsies was 9.08(95%CI: 1.12-73.66) and EUS 22 G core biopsies was 1.99(95%CI: 1.09-3.66).The negative likelihood ratio of EUS 19 G core biopsies was 0.12(95%CI: 0.07-0.24) and EUS 22 G core biopsies was 0.25(95%CI: 0.14-0.41). The diagnostic odds ratio was 84.74(95%CI: 18.31-392.26) for 19 G core biopsies and 10.55(95% CI: 3.29-33.87) for 22 G needles. CONCLUSION EUS 19 G core biopsies have an excellent diagnostic value and seem to be better than EUS 22 G biopsies in detecting the correct etiology for a solid mass.

关键词： Endoscopic ultrasound guided fine needle aspiration Solid mass lesions Endoscopic ultrasound Pancreatic mass Pancreatic cytology Core biopsies 19G procore needle Meta-analysis Systematic review 22G procore needle