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Newly developed self-expandable Niti-S MD colonic metal stent for malignant colonic obstruction

World Journal of Gastrointestinal Surgery 2020年第4期12卷 138-148页

作者： Yuki Miyasako Toshio Kuwai Sauid Ishaq kanae tao Hirona Konishi Ryoichi Miura Yuki Sumida Kazutaka Kuroki Yuzuru Tamaru Ryusaku Kusunoki Atsushi Yamaguchi Hirotaka Kouno Hiroshi Kohno Department of Gastroenterology National Hospital OrganizationKure Medical Center and Chugoku Cancer CenterKure 737-0023Japan Gastroenterology Department Russells Hall HospitalBirmingham City UniversityBirmingham B179BEUnited Kingdom St George’s University University Centre GrenadaWest IndiesGrenada

BACKGROUND Colonic stents are increasingly used to treat acute malignant colonic *** Wall Flex and Niti-S D type stents are the commonly used self-expandable metallic stents available in Japan since *** Flex stent has a risk of stentrelated perforation because of its axial force,while the Niti-S D type stent has a risk of obstructive colitis because of its weaker radial ***-S MD type stents not only overcome these limitations but also permit delivery through highly flexible-tipped smaller-caliber *** To compare the efficacy and safety of the newly developed Niti-S MD type colonic *** This single-center retrospective observational study included 110 patients with endoscopic self-expandable metallic stents placed between November 2011 and December 2018:Wall Flex(Group W,n=37),Niti-S D type(Group N,n=53),and Niti-S MD type(Group MD,n=20).The primary outcome was clinical success,defined as a resolution of obstructive colonic symptoms,confirmed by clinical and radiological assessment within 48 *** secondary outcome was technical success,defined as accurate stent placement with adequate stricture coverage on the first attempt without *** The technical success rate was 100%in Groups W,N,and MD,and the overall clinical success rate was 89.2%(33/37),96.2%(51/53),and 100%(20/20)in Groups W,N,and MD,*** adverse events included pain(3/37,8.1%),poor expansion(1/37,2.7%),and fever(1/37,2.6%)in Group W and perforation due to obstructive colitis(2/53,3.8%)in Group N(likely due to poor expansion).Late adverse events(after 7 d)included stent-related perforations(4/36,11.1%)and stent occlusion(1/36,2.8%)in Group W and stent occlusion(2/51,3.9%)in Group *** stent-related perforation rate in Group W was significantly higher than that in Group N(P<0.05).No adverse event was observed in Group *** In our early and limited experience,the newly developed Niti-S MD type colonic stent was effective

关键词： Colonic stenting New endoscopic colonic stent Malignant colonic obstruction Niti-S WallFlex

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