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Journal of Pharmaceutical Analysis 2014年第6期4卷 374-383页

作者： A.Abiramasundari Rahul P.Joshi Hitesh B.Jalani Jayesh A.Sharma Dhaivat H.Pandya Amit N.Pandya vasudevan Sudarsanam kamala k.vasu Department of Medicinal Chemistry B.V. Pat el PERD Centre Ahmedcibad Gujarat 380054 India

The stability of the drug actarit was studied under different stress conditions like hydrolysis（acid,alkaline and neutral）,oxidation,photolysis and thermal degradation as recommended hy International Conference on Harmonization（ICH） *** was found to be unstable in acidic,basic and photolytic conditions and produced a common degradation product while oxidative stress condition produced three additional degradation *** was impassive to neutral hydrolysis,dry thermal and accelerated stability *** products were identified,isolated and characterized by different spectroscopic *** and the degradation products were synthesized by a new route using green *** chromatographic separation of the drug and its impurities was achieved in a phenomenex luna C18 column employing a step gradient elution by high performance liquid chromatography coupled to photodiode array and mass spectrometry detectors（HPLC-PDAMS）.A specilic and sensitive stability-indicating assay method for the simultaneous determination of the drug *** process related impurities and degradation products was developed and validated.

关键词： Actarit Forced degradation Stability-indicating assay method

Endoscopic ear surgery in middle ear cholesteatoma

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Laparoscopic, Endoscopic and Robotic Surgery 2021年第1期4卷 24-29页

作者： Satish Nair J.G.Aishwarya Nagamani Warrier V Pavithra Aditya Jain Mehrin Shamim krishna Ramanathan Pooja k.vasu Department of ENT-HNS Apollo HospitalsBangaloreKarnatakaIndia

Objective:Endoscope has been used as diagnostic tool for recidivism and as an adjunct to microscopic technique in the management of *** present transcanal endoscopic ear surgery(TEES)is being used as a minimally invasive alternative for microscopic *** aim to evaluate the feasibility,structural,functional and quality of life outcomes of endoscopic technique in middle ear ***:This prospective study was conducted at a tertiary care hospital from January 2017 to January 2018 including 32 adult patients who were treated by TEES for middle ear *** of endoscopic technique was assessed by the conversion rates,visualization of middle ear structures and *** outcomes were evaluated in terms of graft uptake at the third month follow-up and presence of residual or recurrent *** outcomes were evaluated in terms of postoperative air-bone gap closure at third month *** outcomes in terms of post-operative pain,cosmetic score,day of return to daily activities and patient comfort scores were *** quality of life outcomes were evaluated using chronic ear survey(CES)and short form questionnaire12 version 2(SF-12V2)which are disease specific and general quality of life assessment tools ***:Out of 32 patients,endoscopic intact canal wall mastoidectomy was done for 28 and endoscopic canal wall down mastoidectomy in 4 ***(3.1%)patient had to be converted to microscopic *** follow-up period was 32.8 months(9e46 months).There were no post-operative complications in any of our *** mean middle ear structural visibility index score was 8.4±1.4 with the use of zero-degree *** uptake rate at third month follow-up was 100%.Two(6.3%)patients had recurrent disease at 6 months follow-up and were treated by revision endoscopic *** air conduction(51.3±20.2 dB vs.34.5±20.4 dB,p<0.001),and air-bone gap(33.5±11.1 dB vs.16

关键词： Middle ear cholesteatoma Endoscopic technique Transcanal endoscopic ear surgery

Analysis of Nanof luids as Cutting Fluid in Grinding EN-31 Steel

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Nano-Micro Letters 2011年第4期3卷 209-214页

作者： V.vasu k.Manoj kumar Department of Mechanical Engineering National Institute of Technology

Grinding requires high specific energy which develops high temperatures at wheel work piece interface. High temperatures impair work piece quality by inducing tensile residual stress, burn, and micro cracks. Control of grinding temperature is achieved by providing effective cooling and lubrication. Conventional flood cooling is often ineffective due to enormous heat generation and improper heat dissipation. This paper deals with an investigation on using TRIM E709 emulsifier with Al_2O_3 nanoparticles to reduce the heat generated at grinding zone. An experimental setup has been developed for this and detailed comparison has been done with dry, TRIM E709 emulsifier and TRIM E709 emulsifier with Al_2O_3 nanoparticles in grinding EN-31 steel in terms of temperature distribution and surface finish. Results shows that surface roughness and heat penetration were decreased with addition of Al_2O_3 nanoparticles.

关键词： Grinding Al2O3 nanoparticle Temperature distribution Surface roughness EN-31 steel

Evaluation of influence of cold atmospheric pressure argon plasma operating parameters on degradation of aqueous solution of Reactive Blue 198(RB-198)

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Plasma Science and Technology 2020年第5期22卷 114-125页

作者： k NAVANEETHA PANDIYARAJ D vasu P V A PADMANABHAN M PICHUMANI R R DESHMUkH V kANDAVELU Research Division of Plasma Processing(RDPP) Department of PhysicsSri Shakthi Institute of Engineering and TechnologyChinniyam Palayam(post)Coimbatore-641062India Department of Nanoscience and Technology Sri Ramakrishna Engineering CollegeCoimbatore-641022India Department of Physics Institute of Chemical TechnologyMatungaMumbai 400019India Department of Chemistry Sri Shakthi Institute of Engineering and TechnologyL&T bypassChinniyam Palayam(post)Coimbatore-641062India

The intention of this work is to remove Reactive Blue 198(RB-198)dye components from simulated water solution using cold atmospheric pressure argon plasma *** solutions of RB-198 dye were treated as a function of various operating parameters such as applied potential,reaction time and distance between the plasma jet and surface of the *** efficiency of the degradation of RB-198 molecules was explored by means of UV-Vis *** reactive species involved during the treatment process were examined by optical emission spectra(OES).The present hydroxyl radicals(OH·radical)and hydrogen peroxide(H2O2)in the plasma-treated aqueous dye solutions were investigated using various spectroscopic *** other parameters such as total organic carbon(TOC),conductivity and p H were also *** toxicity of plasma-treated RB-198 solution was finally studied by diffusion bacterial analysis and by tracking seed germination *** results show that a higher degradation percentage of99.27%was acquired for the RB-198 treated at higher reaction time and applied potential,and shorter distance between the plasma jet and water *** may be due to the formation of various reactive oxygen(OH·radical,atomic oxygen(O)and H2O2)and nitrogen species(nitric oxide(NO)radicals and N2 second positive system(N2 SPS))during the processes as confirmed by OES analysis and other spectroscopy ***(17.7%-81.8%)and pH(7.5-3.4)values of the plasma-treated RB-198 decreased significantly with respect to various operation parameters,which indicates the decomposition of RB-198 molecules in the aqueous ***,the conductivity of plasma-treated RB-198 aqueous solutions was found to have increased linearly during the plasma treatment due to the formation of various ionic species in aqueous *** toxicity analysis clearly exhibits the non-toxic behavior of plasma-treated RB-198 aqueous solution towards the bacterial growth and germination of see

关键词： RB-198 degradation non-toxicity cold atmospheric pressure plasma jet

Effect of fusion welding processes on tensile properties of armor grade, high thickness, non-heat treatable aluminium alloy joints

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Defence Technology（防务技术） 2019年第3期15卷 353-362页

作者： k. vasu H. Chelladurai Addanki Ramaswamy S. Malarvizhi V. Balasubramanian Department of Mechanical Engineering PDPM Indian Institute of Information Technology Design and Manufacturing Jabalpur Madhya pradesh 482005 India Centre for Materials Joining & Research (CEMAJOR) Department of Manufacturing Engineering Annamalai University Annamalai Nagar -(P.O) Tamil nadu 608002 India

AA5059 is one of the high strength armor grade aluminium alloy that finds its applications in the military vehicles due to the higher resistance against the armor piercing (AP) threats. This study aimed at finding the best suitable process among the fusion welding processes such as gas tungsten arc welding (GTAW) and gas metal arc welding (GMAW) by evaluating the tensile properties of AA5059 aluminium alloy joints. The fracture path was identified by mapping the low hardness distribution profile (LHDP) across the weld cross section under tensile loading. Optical and scanning electron microscopies were used to characterize the microstructural features of the welded joints at various zones. It is evident from the results that GTAW joints showed superior tensile properties compared to GMAW joints and this is primarily owing to the presence of finer grains in the weld metal zone (WMZ) and narrow heat-affected zone (HAZ). The lower heat input associated with the GTAW process effectively reduced the size of the WMZ and HAZ compared to GMAW process. Lower heat input of GTAW process results in faster cooling rate which hinders the grain growth and reduces the evaporation of magnesium in weld metal compared to GMAW joints. The fracture surface of GTAW joint consists of more dimples than GMAW joints which is an indication that the GTAW joint possess improved ductility than GMAW joint.

关键词： Gas tungsten arc welding Gas metal arc welding Armor grade aluminium alloy Tensile properties Microhardness

Stress corrosion cracking behaviour of 7xxx aluminum alloys: A literature review

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Transactions of Nonferrous Metals Society of China 2016年第6期26卷 1447-1471页

作者： A.C.UMAMAHESHWER RAO V.vasu M.GOVINDARAJU k.V.SAI SRINADH Department of Mechanical Engineering National Institute of Technology WarangalWarangal 506004India Nonferrous Materials Technology Development Centre Hyderabad-500058500005India

Stress corrosion cracking （SCC） is degradation of mechanical properties under the combined action of stress and corrosive environment of the susceptible material. Out of eight series of aluminium alloys, 2xxx, 5xxx and 7xxx aluminium alloys are susceptible to SCC. Among them, 7xxx series aluminium alloys have specific application in aerospace, military and structural industries due to superior mechanical properties. In these high strength 7xxx aluminium alloys, SCC plays a vital factor of consideration, as these failures are catastrophic during the service. The understanding of SCC behaviour possesses critical challenge for this alloy. The main aim of this review paper is to understand the effect of constituent alloying elements on the response of microstructural variation in various heat-treated conditions on SCC behavior. Further, review was made for improving the SCC resistance using thermomechanical treatments and by surface modifications of 7xxx alloys. Apart from a brief review on SCC of 7xxx alloys, this paper presents the effect of stress and pre-strain, effect of constituent alloying elements in the alloy, and the effect of environments on SCC behaviour. In addition, the SCC behaviours of weldments, 7xxx metal matrix composites and also laser surface modifications were also reviewed.

关键词： 7xxx aluminum alloy stress corrosion cracking heat treatment microstructure corrosive environment thermomechanical treatment

Transient Combined Convective Heat Transfer over a Stretching Surface in a Non-Newtonian Nanofluid Using Buongiorno’s Model

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Journal of Applied Mathematics and Physics 2016年第2期4卷 443-460页

作者： Rama Subba Reddy Gorla Buddakkagari vasu Sadia Siddiqa Department of Mechanical Engineering University of Akron Akron OH USA Department of Mathematics Motilal Nehru National Institute of Technology Allahabad India Department of Mathematics COMSATS Institute of Information Technology Attock Pakistan

The present paper investigates the transient mixed convective boundary layer flow of an incompressible non-Newtonian quiescent nanofluid adjacent to a vertical stretching surface. The effects of the Brownian motion and thermophoresis are included for the nanofluid. Using appropriate non-similarity transformations the non-dimensional, coupled and highly non-linear system of equations is solved numerically using the efficient keller-box implicit finite difference method for the whole transient from t=0 (initial state) to (final steady-state flow). The box method is unconditionally stable. Numerical results for dimensionless velocity (f’), micro-rotation (g), temperature (θ), nanoparticle volume fraction (Φ) at final steady state flow, skin friction function (), Nusselt number function () and Sherwood number function () have been presented on various parameters inform of tables and graphs. The results indicate that as Nb and Nt increase, the Nusselt number decreases whereas Sherwood number increases at initial and early state time but decreases at the final steady state time. As the k increases, the friction factor decreases whereas surface mass transfer rate and the surface heat transfer rates slightly increase. The results reveal that there is a smooth transition of flow from unsteady state to the final steady state. A special case of our results is in good agreement with an earlier published work. The study has many practical applications such as extrusion of plastic sheets, paper production, glass blowing, metal spinning and drawing plastic films.

关键词： Nanofluid Mixed Convection Non-Newtonian Fluid Brownian Motion keller–Box Numerical Method Boundary Layers

脑室注射催产素对大鼠胃和十二指肠溃疡的作用

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Acta Pharmacologica Sinica 2001年第6期22卷 12-16页

作者： Mohammed AS AD, Deepak Gopal SHEWADE, kallasam kOUMARAVELOU, Benny k ABRAHAM, Sadashivam vasu, Subramanian RAMASWAMY (Department of Pharmacology, Jawaharlal Institute of Post-graduate Medical Education and Research, Pondicherry 605 006, India) Jawaharlal Institute of Post-graduate Medical Education and Research 印度

INTRODUCTION Central neurons that synthesize oxytocin are locatedin the supraoptic(SON) and paraventricular nuclei(PVN) of the hypothalamus. Magnocellular neurons inboth nuclei project to the posterior pituitary gland,

关键词：催产素阿托西班溃疡吲哚美辛组胺半胱胺

Improvement of Plasma Performance with Lithium Wall Conditioning in Aditya Tokamak

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Plasma Science and Technology 2013年第2期15卷 123-128页

作者： M. B. CHOWDHURI R. MANCHANDA J. GHOSH S. B. BHATT Ajai kUMAR B. k. DAS k. A. JADEJA P. A. RAIJADA Manoj kUMAR S. BANERJEE Nilam RAMAIYA Aniruddh MALI ketan M. PATEL Vinay kUMAR P. vasu R. BHATTACHARYAY R. L. TANNA Y. Shankara JOISA P. k. ATREY C. V. S. RAO D. Chenna REDDY P. k. CHATTOPADHYAY R. JHA Y. C. SAXENA Aditya team Institute for Plasma Research Bhat Gandhinagar 382 428 India

Lithiumization of the vacuum vessel wall of the Aditya tokamak using a lithium rod exposed to glow discharge cleaning plasma has been done to understand its effect on plasma performance. After the Li-coating, an increment of ~100 eV in plasma electron temperature has been observed in most of the discharges compared to discharges without Li coating, and the shot reproducibility is considerably improved. Detailed studies of impurity behaviour and hydrogen recycling are made in the Li coated discharges by observing spectral lines of hydrogen, carbon, and oxygen in the visible region using optical fiber, an interference filter, and PMT based systems. A large reduction in O I signal （up to ~40% to 50%） and a 20% to 30% decrease of Ha signal indicate significant reduction of wall recycling. Furthermore, VUV emissions from O V and Fe XV monitored by a grazing incidence monochromator also show the reduction. Lower Fe XV emission indicates the declined impurity penetration to the core plasma in the Li coated discharges. Significant increase of the particle and energy confinement times and the reduction of Zeff of the plasma certainly indicate the improved plasma parameters in the Aditya tokamak after lithium wall conditioning.

关键词： lithiumization wall conditioning impurity Aditya tokamak

More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus

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General Psychiatry 2019年第4期32卷 197-205页

作者： Santosh k Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala kamala Andrzej ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius Department of Psychiatry National Institute of Mental Health and Neuro-SciencesBangaloreIndia Institute of Mental Health BelgradeSerbia Samatvam Endocrinology Diabetes Center and Jnana Sanjeevini Diabetes Hospital and Medical Center BangaloreIndia University of Lower Silesia WroclawPoland Center for Global Mental Health RawalpindiPakistan University of Nairobi NairobiKenya Faculty of Medicine Chulalongkorn UniversityBangkokThailand Pakistan Institute of Medical Sciences IslamabadPakistan Department of Psychiatry and Psychotherapy Medical FacultyUniversity of DusseldorfDusseldorfGermany ProConsult Owings MillsMarylandUSA 不详 Child Adolescent and Family Psychiatry National Institute of Mental HealthDhakaBangladesh Department of Psychiatry King Saud UniversityRiyadhSaudi Arabia IRCCS Ospedale Sacro Cuore Don Calabria NegrarItaly National Research Centre for Psychiatry and Narcology MoscowRussia IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli BresciaItaly University of Milano-Bicocca BicoccaItaly Department of Psychology Catholic UniversityMilanItaly Department of Psychiatry Wroclaw Medical UniversityWroclawPoland

Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted.

关键词： type 2 diabetes mellitus anxious depressed