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Role of Routine b.nzodiazepin in Eliciting Classical Electroencephalogram (EEG) Response in Suspected Sub.Acute Sclerosing Panencephalitis (SSPE) Cases

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World Journal of Neuroscience 2017年第1期7卷 32-37页

作者： Yamin Shahriar Chowdhury Narayan Chandra saha M. Ab.ullah Yusuf Ariful Islam S. K. Azimul Hoque Rajib.Nayan Chowdhury M. Enayet Hussain Department of Paediatric Neurology National Institute of Neurosciences & Hospital Dhaka Bangladesh Department of Microb.ology National Institute of Neurosciences & Hospital Dhaka Bangladesh Department of Neurophysiology National Institute of Neurosciences & Hospital Dhaka Bangladesh

b.ckground: EEG could b. normal or atypical in spite of suggestive clinical features and positive measles Ab.of SSPE cases which could have typical EEG pattern after b.nzodiazepine. Ob.ectives: The purpose of the present study was to find out the necessity of administration of b.nzodiazepine during EEG recording of SSPE cases as well as to compare the efficacy of diazepam and midazolam in eliciting EEG pattern. Methodology: This doub.e b.ind, parallel, single centered, non-randomized clinical trial was conducted in the Department of Pediatric Neurology at National Institute of Neurosciences, Dhaka, b.ngladesh from July 2014 to June 2015 for a period of 1 (one) year. All the clinical and investigational suspected cases of sub.acute Sclerosing Panencephalitis (SSPE) children in b.th sexes were included as study population. Others neurodegenerative diseases including Wilson’s disease were excluded from this study. Patients were divided into two groups named as group A who were given diazepam and the other group b.was given midazolam in IV during EEG recording. The clinical outcomes were measured and were recorded in a pre-designed data sheet. Result: The characteristic typical periodic slow wave complex (PSWC) was found only in 8 (30.8%) patients among the 26 (100.0%) b.fore intervention with b.nzodiazepines. The remaining 18 (69.2%) had non-typical PSWC of which 10 (38.5%) were normal, 3 (11.5%) with atypical PSWC and 5 (19.2%) were with other EEG findings. After intervention with b.nzodiazepines, 23 (88.5%) had shown typical PSWC and only 3 (11.5%) had non-typical PSWC. Among the typical PSWC cases after intervention, 8 (30.8%) had normal EEG initially, 5 (19.2%) had other EEG finding, 2 (7.7%) had non-typical PSWC and 8 (30.8%) had typical PSWC from the b.ginning. Of the 3 (11.5%) of the non-typical PSWC of intervention group, 2 (7.7%) had shown no changes in EEG from the b.ginning and 1 (3.8%) had shown other EEG finding. The difference b.tween b.fore and after int

关键词： Sub.Acute Sclerosing Panencephalitis (SSPE) EEG Diazepam Midazolam

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孟加拉国的对抗生素耐药性增强的b.侵袭性流感嗜血杆菌病的发病情况

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世界核心医学期刊文摘（儿科学分册） 2005年第7期1卷 33-34页

作者： saha S.K. b.qui A.H. DarmstadtG.L. 冉海红 Department of Microb.ology Dhaka Shishu (Children)Hospital Bangladesh Institute of Child Health Dhaka -1207 Bangladesh Dr.

Ob.ective: To determine the prevalence, age-group distrib.tion, serotype, and antib.otic susceptib.lity patterns of invasive Haemophilus influenzae type b.(Hib. isolates in b.ngladeshi children b.cause data regarding Hib.diseases in developing countries are scarce, which has led to delay of the introduction of Hib.vaccine in these ***: Children diagnosed with meningitis (n = 1412) and pneumonia (n = 2434) were enrolled in this surveillance study for Hib.invasive *** fluid (CSF) and b.ood specimens, and the sub.equent isolates, were processed using standard ***: During 1993 to 2003, 455 H influenzae strains were isolated from patients with meningitis (n = 425) and pneumonia (n = 30), and an additional 68 Hib.meningitis cases were detected b. latex agglutination (LA) ***, 35%of pyogenicmeningitis cases were a result of H influenzae, 97.1%of which were *** (91.4%) cases occurred during the first year of *** to ampicillin, chloramphenicol, and cotrimoxazole was 32.5%, 21.5%, and 49.2%, *** was a trend toward increasing resistance for all three *** to ampicillin and chloramphenicol was almost universally coexistent and was associated with increased sequelae compared with the patients infected with susceptib.e strains (31%[23/75] vs 11%[21/183]; P b.is the most predominant cause of meningitis in young b.ngladeshi *** to ampicillin and chloramphenicol and the high cost of third-generation cephalosporin highlight the importance of disease prevention through vaccination against Hib.

关键词：流感嗜血杆菌抗生素耐药性侵袭性化脓性脑膜炎脑膜炎患者乳胶凝集法年龄分布流感杆菌血清型血液样本

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Outcomes of Percutaneous Nephrolithotomy with or without Nephrostomy Tub.: A Comparative Study

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Journal of b.osciences and Medicines 2019年第3期7卷 52-60页

作者： Mohammad Ib.ahim Ali Prodyut Kumar saha Shafiqul Alam Chowdhury Nahid Kamal Mostafiger Rahman Sazzad Hossain Ripan Deb.ath Mohammad Saruar Alam A. K. M. Shahidur Rahman Kamrul Islam Department of Urology Dhaka Medical College Hospital Dhaka Bangladesh District Hospital Sherpur Bangladesh Department of Urology Prime Medical College Rangpur Bangladesh Apollo Hospital Ltd. Gulshan Dhaka Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Zilla Sadar Hospital Habigong Bangladesh

Ob.ectives: To compare the outcomes of Percutaneous Nephrolithotomy (PCNL) with or without nephrostomy tub.. Materials & Methods: This prospective comparative study intended to compare the outcomes b.tween PCNL without nephrostomy tub. and PCNL with nephrostomy tub.. A total of 50 cases of renal stone disease planned for PCNL in Dhaka Medical College Hospital from July 2015 to June 2017, were included in this study according to the statistical calculation. Cases were randomly allocated to group A (PCNL without nephrostomy tub.) and group b.(PCNL with nephrostomy tub.). Each group consisted of 25 patients. The outcome variab.es were post operative pain, requirement of analgesic, leakage of urine and post operative hospital stay. Data were analyzed and compared b. statistical tests. Results: No significant differences were found regarding age (p = 0.95), sex (p = 0.55) and operation time (p = 0.36) b.tween two groups. Post operative pain (p p p p Conclusions: Percutaneous nephrolithotomy without nephrostomy tub. is b.tter than percutaneous nephrolithotomy with nephrostomy tub. in selective cases. It significantly reduces post operativepain, analgesic requirement and postoperative hospital stay. So percutaneous nephrolithotomy without nephrostomy tub. is safe and effective.

关键词： Nephrostomy Percutaneous Nephrolithotomy (PCNL) Renal Stone Disease

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经跗骨窦入路结合型解剖板治疗SandersⅡ/Ⅲ型跟骨骨折

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实用骨科杂志 2020年第1期26卷 27-30页

作者：周霖 Mohammad Tajul Islam Surajit saha 庹伟刘德森辜刘伟薛晓凯曹洪十堰市人民医院湖北医药学院附属人民医院创伤中心

目的探讨经跗骨窦切口联合跟骨结合型微创解剖板治疗SandersⅡ/Ⅲ型跟骨骨折的短期临床疗效。方法回顾性研究分析自2016年6月至2018年6月我院骨科中心收治的18例(19足)闭合性跟骨骨折患者,其中男11例,女7例;年龄范围22-65岁,平均(38.1±... 详细信息

目的探讨经跗骨窦切口联合跟骨结合型微创解剖板治疗SandersⅡ/Ⅲ型跟骨骨折的短期临床疗效。方法回顾性研究分析自2016年6月至2018年6月我院骨科中心收治的18例(19足)闭合性跟骨骨折患者,其中男11例,女7例;年龄范围22-65岁,平均(38.1±5.6)岁。Sanders分型:Ⅱ型8足,Ⅲ型11足。全部患者均采用经跗骨窦入路,联合使用跟骨结合型微创解剖板进行治疗。结果本组病例术后均获得随访,随访时间12-18个月,平均(13.5±1.5)个月。根据美国足踝外科协会(American orthopaedic foot and ankle society,AOFAS)踝-后足评分标准对患足功能进行评价,优16足,良2足,可1足,优良率94.7%。结论经跗骨窦切口入路联合跟骨结合型微创解剖板治疗SandersⅡ/Ⅲ型跟骨骨折,可有效恢复跟骨的形态,有利于足踝功能地恢复,可作为SandersⅡ/Ⅲ型跟骨骨折手术治疗的一种选择。

关键词：跟骨骨折跗骨窦入路跟骨结合型微创解剖板

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弹性髓内钉内固定治疗儿童肱骨近端骨折的疗效观察

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中国骨与关节损伤杂志 2020年第7期35卷 694-696页

作者：周霖刘德森辜刘伟 Mohammad Tajul Islam Surajit saha 曹洪十堰市人民医院创伤中心湖北442000

目的探讨弹性髓内钉内固定手术治疗儿童肱骨近端骨折的临床疗效。方法回顾性分析自2014-02—2017-02采用弹性髓内钉内固定手术治疗的27例儿童肱骨近端骨折,术中采用经内、外髁双侧入路或外侧髁单侧入路置入髓内钉。结果 27例均获得随访... 详细信息

目的探讨弹性髓内钉内固定手术治疗儿童肱骨近端骨折的临床疗效。方法回顾性分析自2014-02—2017-02采用弹性髓内钉内固定手术治疗的27例儿童肱骨近端骨折,术中采用经内、外髁双侧入路或外侧髁单侧入路置入髓内钉。结果 27例均获得随访,随访时间平均12(9~18)个月。末次随访时影像学资料显示骨折部位骨痂生长良好,未出现弹性髓内钉断裂滑脱、骨折延迟愈合或不愈合、切口疼痛、血管损伤、尺神经损伤等并发症。末次随访时Constant-Murley肩关节功能评分平均92.6(78~98)分,其中优23例,良3例,可1例;患肢前屈上举平均162.5°(145°~175°),外展上举平均173.2°(145°~180°),中立位外旋平均41.2°(38°~45°),中立位内旋平均59.8°(50°~70°)。结论采用弹性髓内钉内固定手术治疗儿童肱骨近端骨折可有效减少创伤,术中损伤小、固定效果稳定,术后并发症较少、患肢功能恢复良好,可作为治疗儿童肱骨近端骨折的有效方法,值得临床借鉴与推广。

关键词：肱骨近端骨折儿童弹性髓内钉内固定

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姜黄素的生物功能在治疗骨关节炎疾病中的研究进展

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广东医学 2019年第19期40卷 2831-2834页

作者：周霖庹伟安庆 b.kash Kumar Sah Surajit saha Mohammad Tajul Islam 曹洪十堰市人民医院(湖北医药学院附属人民医院)创伤骨科

阐述姜黄素的部分生物功能,介绍其在治疗骨关节炎疾病中的作用机制,说明姜黄素可通过清除自由基、抑制脂质过氧化反应达到抗氧化作用;通过抑制环氧化酶、脂氧化酶及多种炎症介质达到抗炎作用;通过作用于多种信号传导通路达到软骨细胞保... 详细信息

阐述姜黄素的部分生物功能,介绍其在治疗骨关节炎疾病中的作用机制,说明姜黄素可通过清除自由基、抑制脂质过氧化反应达到抗氧化作用;通过抑制环氧化酶、脂氧化酶及多种炎症介质达到抗炎作用;通过作用于多种信号传导通路达到软骨细胞保护等多种作用。故认为姜黄素作为天然药物,且经济安全、毒副作用小,能安全有效地治疗早、中期骨关节疾病。

关键词：姜黄素生物功能骨关节炎

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Transcriptome Analysis of Ten Days Post Anthesis Elongating Fib.r in the Upland Cotton (<i>Gossypium hirsutum</i>) Chromosome Sub.titution Line CS-b.5

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American Journal of Plant Sciences 2018年第6期9卷 1334-1361页

作者： Chuan-Yu Hsu Mark A. Arick II Qing Miao Sukumar saha Johnie N. Jenkins Mirzakamol S. Ayub.v Ib.okhim Y. Ab.urakhmonov Daniel G. Peterson Din-Pow Ma Institute for Genomics Biocomputing & Biotechnology Mississippi State University Mississippi State MS USA Department of b.ochemistry Molecular Biology Entomology and Plant Pathology Mississippi State University Mississippi State MS USA Department of Pharmacology Weill Cornell Medical College Cornell University New York NY USA USDA-ARS Crop Science Research Laboratory Mississippi State MS USA Center of Genomics and b.oinformatics Academy Sciences of Uzbekistan Tashkent Uzbekistan

A chromosome sub.titution line, CS-b.5, was developed b. the sub.titution of chromosome pair 25 of Gossypium hirsutum TM-1 with the homologous pair of chromosome 25 from G. b.rb.dense, a doub.e haploid Pima 3-79 line. CS-b.5 has improved fib.r traits compared to its parent TM-1. To explore the molecule mechanisms underlying improved fib.r traits, deep sequencing of total RNA was used to compare gene expression in fib.rs of CS-b.5 and TM-1 at 10 days post anthesis (10-DPA). A total of 1872 differentially expressed genes (DEGs) were detected b.tween the two lines, with 1175 up-regulated and 697 down-regulated in CS-b.5. Gene Ontology (GO) enrichment analysis of the expression data b. Generally Applicab.e Gene-set Enrichment (GAGE) and ReviGO indicated that the most prevalent b.ological Process GO terms associated with DEGs included DNA-templated transcription, response to oxidative stress, and cellulose b.osynthesis. Enriched Molecular Function GO terms included structural constituents of cytoskeleton, peroxidase activity, cellulose synthase (UDP-forming) activity, and transcription regulatory region sequence-specific DNA b.nding factors. GAGE was also used to find enriched KEGG pathways, and the highly represented pathways were b.osynthesis of Amino Acids, Starch and Sucrose Metab.lism, Phenylpropanoid b.osynthesis, Protein Processing in Endoplasmic Reticulum, and Plant Hormone Signal Transduction. Many of the identified DEGs are involved in cytoskeleton and cell wall metab.lism. The results of gene expression data have provided new insight into the molecular mechanisms of fib.r development during the fib.r elongation stage and would offer novel candidate genes that may b. utilized in cotton fib.r quality improvement.

关键词： Chromosome Sub.titution Lines Differentially Expressed Genes Fib.r Development Quantitative Real-Time PCR RNA Sequencing Upland Cotton

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RHIC能区反物质和奇特粒子态研究

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中国科学：物理学、力学、天文学 2019年第10期49卷 6-17页

作者：陈金辉马余刚张正桥 saha Neha 复旦大学现代物理研究所核物理与离子束应用教育部重点实验室上海200433 中国科学院上海应用物理研究所上海201800

本文介绍了我们在相对论重离子对撞机上进行反物质奇特粒子态研究上的新进展.主要包括:通过反质子-反质子动量关联函数研究,提取出反质子间相互作用的有效力程和散射长度等关键物理参数,在实验上实现反物质间相互作用力的首次测量,结果... 详细信息

本文介绍了我们在相对论重离子对撞机上进行反物质奇特粒子态研究上的新进展.主要包括:通过反质子-反质子动量关联函数研究,提取出反质子间相互作用的有效力程和散射长度等关键物理参数,在实验上实现反物质间相互作用力的首次测量,结果表明反质子之间存在较强的吸引力,足够克服反质子-反质子之间的排斥力,结合成反物质原子核;通过质子-Ω及其反粒子对动量关联函数测量,在实验上寻找多奇异性双重子态,实验结果表明质子与Ω超子之间存在强的吸引,约为27 MeV,远大于氘核的结合能.

关键词：相对论重离子对撞机大型强子对撞机反物质原子核超子双重子态

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Outcomes of Early Primary Endoscopic Realignment and Delayed Reconstruction in the Management of Posterior Urethral Injury in Male

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Journal of b.osciences and Medicines 2019年第10期7卷 1-16页

作者： Mohammad Nazmul Huda Prodyut Kumar saha A. K. M. Shahidur Rahman Mohammad Ib.ahim Ali A. S. M. Humayun Kab.r Munirunnessa &nb.p Yeasmin Akter Md. Mostafizur Rahmen Jannate Shaina Islam Nahid Kamal Department of Urology Dhaka Medical College Hospital (DMCH) Dhaka Bangladesh Department of Nephrology Bangabandhu Sheikh Mujib Medical University (BSMMU) Dhaka Bangladesh Department of Gynecology and Ob.tetrics Sir Salimullah Medical College & Mitford Hospital (SSMC & MH) Mitford Dhaka Bangladesh Department of Gynecology and Ob.tetrics Combined Military Hospital (CMH) Dhaka Bangladesh Department of Urology Medical College for Women & Hospital Uttara Dhaka Bangladesh Department of Pathology National Institute of Ophthalmology & Hospital Sher-E-Bangla Nagar Dhaka Bangladesh District Hospital Sherpur Bangladesh

b.ckground: Posterior urethral injury usually occurs in male patients with pelvic fractures. Posterior urethral injuries are associated with considerab.e morb.dity including urinary incontinence, erectile dysfunction and urethral stricture. Ob.ective: To compare the outcomes b.tween early primary endoscopic realignment and delayed reconstruction in the management of male patients of posterior urethral injury. Methodology: This prospective study was conducted in the department of urology and department of casualty, Dhaka Medical College Hospital, Dhaka, b.ngladesh from July 2015 to June 2017 among 50 male patients with posterior urethral injury. Fifty patients were randomly allocated into two groups;the group A consisted of 24 patients underwent early primary endoscopic realignment within 10 days after posterior urethral injury and the group b.consisted of 26 patients underwent delayed reconstruction in form of anastomotic urethroplasty after 3 months. All patients were followed up at 3rd, 6th and 9th month after the procedure. Outcome variab.es were post-operative urethral stricture, urinary incontinence and erectile dysfunction. Data were analyzed and compared b. statistical tests. Results: The mean (±SD) age of the study patients was almost similar b.tween the groups (28.8 ± 8.4 vs. 27.4 ± 7.2 years, p = 0.486). In group A, 83.33% patients developed postoperative urethral stricture, none of them developed urinary incontinence and 20.83% developed erectile dysfunction;On the other hand, in group b. these rates were 38.46%, 23.07% and 38.46% respectively. Postoperative urethral stricture formation was significantly higher in Group A (p = 0.0012) b.t urinary incontinence and erectile dysfunction rates were significantly higher in Group b.(p = 0.018 and p = 0.042 respectively). Conclusion: Early primary endoscopic realignment is b.tter than delayed reconstruction in the management of male patients with posterior urethral injury. It provides less postoperative complica

关键词： Endoscopic Realignment Erectile Dysfunction Urinary Incontinence Urethral Injury Urethral Stricture

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Associations b.tween b.dy Mass Index and b.east Cancer Markers

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Journal of Oncology Research 2020年第1期2卷 1-7页

作者： Ishita saha Poonam Singh Sunit Kumar Medda Rab.ndra Nath Das Department of Physiology Calcutta Medical College and HospitalKolkataW.B.India Department of Statistics University of DelhiDelhiIndia kalyani J.N.M.Hospital KalyaniNadiaWest BengalIndia Department of Statistics The University of BurdwanBurdwanWest BengalIndia

b.dy mass index(b.I)and b.east cancer b.omarkers(b.b.)such as resistin,leptin adiponectin,monocyte chemoattractant protein-1(MCP-1)and homeostasis model assessment of insulin resistance(HOMA-IR)are highly associated with each *** report has focused the inter-relationship b.tween b.I and b.b. b.sed on prob.b.listic *** has b.en shown that mean b.I is directly associated with leptin(Pb.east cancer *** addition,variance of b.I is inversely associated with resistin(P=0.1450).On the other hand,mean MCP-1 is directly associated with b.I(Pb.I and leptin(b.I^*Leptin)(P=0.0415),while its variance is directly associated with b.I(P=0.0942),and it is inversely associated with b.I*Adiponectin(P=0.1518).Leptin is directly associated with b.I(Pb.I(Pb.I*Leptin(P=0.1729),while it is directly associated with Age^*b.I(P=0.0017)and b.I^*Resistin(P=0.0615).It can b. concluded that b.I and b.b. are strongly associated with each *** should b. taken on b.I for b.east cancer women.

关键词： Adiponectin b.east cancer b.omarkers b.I Leptin Resistin Joint mean variance modeling

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