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避免折价融资私营企业有何变通之策?

商业周刊（中文版） 2023年第2期 34-35页

作者： Hema parmar Loukia Gyftopoulou Linly Lin 王非(译) 不详

对于在科技热潮中实现估值飙涨的初创企业来说,恐怕没有什么比折价融资更难接受的事情了。投资者向迅速增长的业务追加资金,在投资额接近的情况下要求换取更多股权,就是折价融资。这会导致公司估值下降一一有时降幅之大令人咋舌。

关键词：初创企业折价私营企业融资公司估值追加资金飙涨投资额

Identification of a SSR marker (TOM-144) linked to Fusarium wilt resistance in <i>Solanum lycopersicum</i>

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American Journal of Molecular Biology 2013年第4期3卷 241-247页

作者： Pritesh parmar Ankit Sudhir R. Preethi Bhaumik Dave Ketankumar Panchal Ramalingam B. Subramanian Arvind Patel K. B. Kathiria B. R. D. School of Biosciences Sardar Patel University Vallabh Vidyanagar India Vegetable research station Anand Agricultural University Anand India

With the discovery of molecular markers and marker assisted selection technology, the research has entered into a new era and has made it possible to develop new and more informative PCR-based markers, including SSR, and to further facilitate the use of markers in tomato breeding. The present study is a step to introduce a new SSR marker (TOM-144) which was deduced after evaluation of eight microsatellite loci amongst the twenty-one different tomato cultivars. The marker selected was inherited and segregated in mendelian fashion as demonstrated in successive generation of a cross between parent cvs. H-24 x GT-2.

关键词： Fusarium Wilt Molecular Marker Tomato

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以慈善的名义

Protective effect of naringenin on acetic acid-induced ulcerative colitis in rats

作者： (英)英德杰特·帕马(Inderjeet parmar)

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World Journal of Gastroenterology 2013年第34期19卷 5633-5644页

作者： Salim S Al-Rejaie Hatem M Abuohashish Maher M Al-Enazi Abdullah H Al-Assaf Mihir Y parmar Mohammed M Ahmed Department of Pharmacology andToxicology College of PharmacyKing Saud University Department of Medical Laboratory Sciences College of Applied Medical SciencesSalman bin Abdulaziz University Department of Science and Nutrition College of Food and Agricultural SciencesKing Saud University

AIM:To evaluate the ameliorative effect of naringenin(NG)during ulcerative colitis(UC)in ***:Rats were treated with three different doses(25,50 and 100 mg/kg per day)of NG and a single dose of mesalazine(MES,300 mg/kg per day)for seven days prior to ulcerative colitis induction by4%acetic acid(AA).Twenty four hours after AA rectal administration,animals were scarified and the colonic tissues were *** mucus content was estimated using Alcian blue dye binding *** colon tissues,levels of total glutathione sulphadryls(T-GSH),non-protein sulphadryls(NP-SH)and thiobarbituric acid reactive substances(TBARS)were *** activities of the antioxidant enzymes,catalase(CAT)and superoxide dismutase(SOD)were *** of nucleic acids(DNA and RNA)and total protein were also estimated in colon *** levels of tumor necrosis factor-(TNF-),interleukin-1(IL-1),interleukin-6(IL-6),prostaglandin E2(PGE2)and nitric oxide(NO)were *** cross section of colitis tissue the histopathological changes were ***:Colonic mucus content was decreased in AA compared to controls(587.09±65.59 mg/kg vs941.78±68.41 mg/kg,P<0.001).AA administration markedly reduced T-GSH(5.25±0.37 nmol/L vs 3.04±0.24 nmol/L,P<0.01),NP-SH(3.16±0.04 nmol/L vs 2.16±0.30 nmol/L,P<0.01),CAT(6.77±0.40 U/mg vs 3.04±0.2 U/mg,P<0.01)and SOD(3.10±0.11U/mg vs 1.77±0.18 U/mg,P<0.01)while TBARS,TNF-,IL-1,IL-6,PGE2 and NO levels(15.09±3.84nmol/L vs 59.90±16.34 nmol/L,P<0.01;113.56±1.91 pg/mg vs 134.24±4.77 pg/mg,P<0.01;209.20±36.38 pg/mg vs 422.19±31.47 pg/mg,P<0.01;250.83±25.09 pg/mg vs 638.58±115.9 pg/mg,P<0.01;248.19±36.98 pg/mg vs 541.74±58.34 pg/mg,P<0.01 and 81.26±2.98 mmol/g vs 101.90±10.73 mmol/g,P<0.001)were increased in colon of rats with UC compared controls *** supplementation,significantly and dose dependently increased the colonic mucus *** elevated TBARS levels were significantly decreased(39.35±5.86nmol/L,P<0

关键词： Naringenin Ulcerative colitis Inflammatory bowel disease Oxidative stress

COVID-19 pandemic effects on the distribution of healthcare services in India: A systematic review

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World Journal of Virology 2022年第4期11卷 186-197页

作者： Nirav Nimavat Mohammad Mehedi Hasan Sundip Charmode Gowthamm Mandala Ghanshyam R parmar Ranvir Bhangu Israr Khan Shruti Singh Amit Agrawal Ashish Shah Vishi Sachdeva Department of Community Medicine Dr.Kiran C Patel Medical College and Research InstituteBharuch 392001India Department of Biochemistry and Molecular Biology Mawlana Bhashani Science and Technology UniversityTangail 1902Bangladesh Department of Anatomy All India Institute of Medical SciencesRajkot 360006GujaratIndia Independent Researcher Centre Groove High SchoolGreenwoodIN 46143United States Department of Pharmacy Sumandeep VidyapeethVadodara 391760India Department of Medical Caribbean Medical UniversityDes PlainesIL 60018United States Shifa International Hospital Islamabad 999010Pakistan Department of Pharmacology All India Institute of Medical SciencesPatna 801507India Department of Paediatrics Gandhi Medical CollegeBhopal 462001India Department of Medical Adesh Institute of Medical Sciences and ResearchBathinda 151009India

BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has brought fundamental changes to our problems and priorities,especially those related to the healthcare *** was one of the countries severely affected by the harsh consequences of the COVID-19 *** To understand the challenges faced by the healthcare system during a *** The literature search for this review was conducted using PubMed,EMBASE,Scopus,Web of Science,and Google *** also used Reference Citation Analysis(RCA)to search and improve the *** focused on the published scientific articles concerned with two major vital areas:(1)The Indian healthcare system;and(2)COVID-19 pandemic effects on the Indian healthcare *** The Indian healthcare system was suffering even before the *** pandemic has further stretched the healthcare services in *** main obstacle in the healthcare system was to combat the rising number of communicable as well as noncommunicable *** the pandemic measures,there was a diversion of focus of the already established healthcare services away from the chronic conditions and *** disruption of the vaccination services may have more severe short and long-term consequences than the pandemic’s adverse *** Severely restricted resources limited the interaction of the Indian healthcare system with the COVID-19 ***-establishment of primary healthcare services,maternal and child health services,noncommunicable diseases programs,National Tuberculosis Elimination Program,*** important to prevent serious long-term consequences of this pandemic.

关键词： COVID-19 Healthcare system Pandemic India Healthcare services

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逆境之下对冲基金降费求生

商业周刊（中文版） 2020年第13期 22-24页

作者： Nishant Kumar Hema parmar Demetrios Pogkas 牛小婧(译) 不详

●近年来表现平淡的对冲基金行业在尝试下调费率吸引投资者牛津大学(University of Oxford)教授卢多维克·法表示在冠状病毒疫情席卷全球市场之前,对冲基金费率便已呈现缩水势头。现在,费率的下降已无可逆转。规模达3万亿美元的对冲基... 详细信息

●近年来表现平淡的对冲基金行业在尝试下调费率吸引投资者牛津大学(University of Oxford)教授卢多维克·法表示在冠状病毒疫情席卷全球市场之前,对冲基金费率便已呈现缩水势头。现在,费率的下降已无可逆转。规模达3万亿美元的对冲基金行业多年来一直顶着收费高昂的恶名,对冲基金所运作的投资组合一般仅向机构和富有的个人开放。

关键词：对冲基金投资组合基金费率降费牛津大学冠状病毒

Bicornuate Uterus: Infertility Treatment and Pregnancy Continuation without Cerclage:An Unusual Case

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Open Journal of Obstetrics and Gynecology（妇产科期刊） 2014年第15期

作者： Meenal parmar Surabhi Tomar

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优先开展抗肿瘤治疗延迟的研究

英国医学杂志中文版 2021年第4期24卷 183-184页

作者： Ambica parmar Kelvin K W Chan 董方(译) 张宏艳(校) Odette Cancer Centre Sunnybrook Health Sciences CentreUniversity of Toronto2075 Bayview AvenueRoom T2-058TorontoON M4N 3M5Canada Canadian Centre for Applied Research in Cancer Control TorontoONCanada 甘肃省肿瘤医院放疗科解放军总医院第五医学中心肿瘤学部

如何能及时进行抗肿瘤治疗,是广大患者及临床医生当务之急要解决的问题。大量证据表明,对于急需有效治疗的肿瘤患者而言,过长的等待时间会导致疾病预后不良1-5,由此而催生了针对多种肿瘤治疗措施的目标等待时间问题6-7。自2020年3月,新... 详细信息

如何能及时进行抗肿瘤治疗,是广大患者及临床医生当务之急要解决的问题。大量证据表明,对于急需有效治疗的肿瘤患者而言,过长的等待时间会导致疾病预后不良1-5,由此而催生了针对多种肿瘤治疗措施的目标等待时间问题6-7。自2020年3月,新型冠状病毒肺炎(COVID-19)已经推迟了许多医疗辖区的患者接受抗肿瘤治疗的时间。

关键词：临床医生等待时间预后不良抗肿瘤治疗新型冠状病毒治疗措施肿瘤患者有效治疗

0.3%加替沙星和0.3%环丙沙星治疗细菌性角膜炎的疗效观察

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世界核心医学期刊文摘（眼科学分册） 2006年第5期2卷 9-10页

作者： parmar P. Salman A. Kalavathy C.M. 潘佳鸿 Institute of Ophthalmology Joseph Eye Hospital Tiruchirapalli 620 001 (Tamil Nadu) India

PURPOSE: To compare the bacteriologic and clinical efficacy of gatifloxacin and ciprofloxacin for the treatment of bacterial keratitis. DESIGN: Prospective, randomized clinical trial. METHODS: A total of 104 eyes of 104 patients with bacterial keratitis seen at a tertiary eye-care center were randomized to treatment with gatifloxacin 0.3%eyedrops (GAT group, 50 eyes) or ciprofloxacin 0.3%eyedrops (CIP group, 54 eyes). Patients and the treating physician were masked to the antibiotic being used. Main outcome measure studied was healing of the ulcer. Patients lost to follow-up before complete healing were excluded from further analysis. RESULTS: A significantly higher proportion of ulcers in the GAT group exhibited complete healing compared with those in the CIP group (39 eyes 95.1% vs 38 80.9% ; P=.042). Gatifloxacin demonstrated a significantly better action than ciprofloxacin against gram-positive cocci in vitro (P < .001), and the percentage of ulcers caused by these pathogens that healed in the GAT group was significantly better than in the CIP group (P=.009). Mean time taken for healing of ulcer and the efficacy against gram-negative bacteria did not significantly differ between the two groups. CONCLUSIONS: Gatifloxacin had a significantly better action against gram-positive cocci both in vitro and in vivo when compared with ciprofloxacin. In view of these organisms being the leading cause of keratitis worldwide, gatifloxacin may be a preferred alternative to ciprofloxacin as the first-line monotherapy in bacterial keratitis.

关键词：环丙沙星眼药水细菌性角膜炎加替沙星治疗组疗效观察前瞻性随机临床试验抗生素治疗临床疗效防治中心愈合情况