检索结果-南通市图书馆

Combined treatment with dihydrotestosterone and lipopolysaccharide modulates prostate homeostasis by upregulating TNF-α from M1 macrophages and promotes proliferation of prostate stromal cells

引用

Asian Journal of Andrology 2022年第5期24卷 513-520页

作者： Yu Tong Yi-Jun guo Qin Zhang Hai-Xia Bi kai kai Ren-Yuan Zhou Department of Urology Jing’an District Central HospitalFudan UniversityShanghai 200040China Department of Pathology Jing’an District Central HospitalFudan UniversityShanghai 200040China

Androgens and chronic inflammation,which play essential roles in the development of benign prostatic hyperplasia(BPH),are considered to be important factors in disorders of prostate *** two factors may lead to pathological hyperplasia in the prostate transition zone of patients with ***,few studies have examined the mechanism of how dihydrotestosterone(DHT)affects chronic inflammation in prostate tissue during the progression of *** study examined the performance of DHT in lipopolysaccharide-treated M1 macrophages and the subsequent effects on the proliferation of prostate stromal and epithelial *** found that DHT increased secretion of the pro-inflammatory factor tumor necrosis factor(TNF)-αfrom M1 macrophages differentiated from THP-1 *** supernatant of M1 macrophages promoted the proliferation of WPMY-1 prostate stromal cells by upregulating B-cell lymphoma-extra large(Bcl-xL)and cellular Myc(c-Myc)levels by activating TNF-α-mediated nuclear factor-kappa B(NF-κB)and mitogen-activated protein kinase(MAPK)***,this supernatant increased the expression of androgen receptor in WPMY-1 cells,which was TNF-α-***,TNF-αprotein expression was significantly higher in patients with BPH and a large prostate volume than that in those with a small prostate *** analysis showed that higher serum testosterone combined with prostate-specific androgen concentrations was related to TNF-α*** study suggests that DHT modulates the inflammatory environment of BPH by increasing TNF-αexpression from lipopolysaccharide-treated M1 macrophages and promotes the proliferation of prostate stromal *** TNF-α,but not DHT,may be a promising strategy for patients with BPH.

关键词： benign prostatic hyperplasia dihydrotestosterone inflammation macrophage tumor necrosis factor-alpha

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrodynamic Evolution and Hydrocarbon Accumulation in the Dabashan Foreland Thrust Belt,China

引用

Acta Geologica Sinica(English Edition) 2012年第4期86卷 912-923页

作者： ZENG Jianhui guo kai TIAN Kun XU Tianwu State Key Laboratory of Petroleum Resource and Prospecting China University of Petroleum Faculty of Geosciences China University of PetroleumChangping Sinopec Zhongyuan Oilfield Exploration and Development Science Institute

There are two plays in the Dabashan foreland tectonic belt： the upper and the lower plays. The lower play experienced one sedimentary hydrodynamic stage, two burial hydrodynamic stages, two tectonic hydrodynamic stages and two infiltration hydrodynamic stages from the Sinian to the Cenozoic, while the upper play had one sedimentary hydrodynamic stage, one burial hydrodynamic stage, two tectonic hydrodynamic stages and one infiltration hydrodynamic stage from the Permian to the Cenozoic. Extensive flows of both sedimentary water, including hydrocarbons, and deep mantle fluid occurred in the Chengkou faults during collision orogeny in the Middle-Late Triassic Indosinian orogeny, and fluid flow was complicated during intracontinental orogeny in the Middle-Late Jurassic. In addition to these movements, infiltration and movement of meteoric water took place in the Chengkou faults, whereas in the covering-strata decollement tectonic belt, extensive sedimentary water flow （including hydrocarbons） occurred mainly in the Zhenba and Pingba faults. During the stage of rapid uplift and exhumation from the Cretaceous to the Cenozoic, the fluid flow was characterized mainly by infiltration of meteoric water and gravity-induced flow caused by altitude difference, whereas sedimentary water flow caused by tectonic processes was relatively less significant. Sedimentary water flow was more significant to the lower play in hydrocarbon migration and accumulation during collision orogeny in the Middle-Late Triassic Indosinian orogeny, but its influence is relatively slight on the upper play. On one hand, hydrodynamics during intracontinental orogeny in the Middle-Late Jurassic adjusted, reformed or oven destroyed oil reservoirs in the lower play; on the other hand, it drove large amounts of hydrocarbons to migrate laterally and vertically and is favorable for hydrocarbon accumulation. Infiltration hydrodynamics mainly adjusted and destroyed oil reservoirs from the Cretaceous to the Cenoz

关键词： hydrodynamic evolution and its characteristics hydrocarbon migration accumulation and preservation the Dabashan foreland tectonic belt

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Variational Approach for Fractional Diffusion-Wave Equations on Cantor Sets

引用

Chinese Physics Letters 2012年第6期29卷 61-63页

作者： WU guo-Cheng WU kai-Teng College of Water Resources and Hydropower Sichuan UniversityChengdu 610065 Key Laboratory of Numerical Simulation of Sichuan Province Neijiang Normal UniversityNeijiang 641112

The fractional variational iteration method is used to investigate the diffusion-wave problem on Cantor *** approximate solution is obtained in forms of fractional differentiable functions.

关键词： functions Cantor fractional

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Preparation of Nylon MXD6/EG/CNTs Ternary Composites with Excellent Thermal Conductivity and Electromagnetic Interference Shielding Effectiveness

引用

Chinese Journal of Polymer Science 2017年第12期35卷 1497-1507页

作者： Yi-lan guo Run-zhi Zhang kai Wu 陈枫傅强 College of Polymer Science and Engineering State Key Laboratory of Polymer Materials EngineeringSichuan University

In this article, hybrid fillers with different dimensions, namely, 2-dimensional（2-D） expanded graphite（EG） and 1-dimensional（1-D） multi-walled carbon nanotubes（CNTs）, were added to aromatic nylon MXD6 matrix via melt-blending, to enhance its thermal and electrical conductivity as well as electromagnetic interference shielding effectiveness（EMI SE）. For ternary composites of MXD6/EG/CNTs, the electrical conductivity reaches up nine orders of magnitude higher compared to that of the neat MXD6 sample, which turned the polymer-based composites from an insulator to a conductor, and the thermal conductivity has been enhanced by 477% compared with that of neat MXD6 sample. Meanwhile, the EMI SE of ternary composite reaches ~50 d B at the overall filler loading of only 18 wt%. This work can provide guidance for the preparation of polymer composites with excellent thermal and electrical conductivity via using hybrid filler.

关键词： Thermal and electrical conductivity Electromagnetic interference shielding Hybrid filler Synergistic effect

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A young male with abdominal distention and fever after cardiopulmonary resuscitation treatment

引用

World Journal of Emergency Medicine 2022年第5期13卷 409-411页

作者： guo-feng Chen kai-bo Chen Jian Chen Department of Gastrointestinal Surgery the Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China

Abdominal distention after cardiopulmonary resuscitation(CPR)is a common phenomenon that presents in the emergency *** is caused by a long period of bag-valve mask ventilation or esophageal ***,a rare but life-threating diagnosis should be considered when distention progresses ***,we reported a patient who developed a fever and abdominal pain that couldn’t be relieved by gastric decompression.

关键词： abdominal fever resuscitation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Structural and electrical properties of high Curie temperature Aurivillius phase composite ceramics with largely enhanced piezoelectricity

引用

Science China(Technological Sciences) 2016年第7期59卷 1048-1053页

作者： WANG YunLi CAI kai MA JingTao ZENG Fei guo Dong Institute of Acoustics Chinese Academy of Sciences Beijing 100190 China Beijing Center for Physical and Chemical Analysis Beijing 100089 China School of Materials Science & Engineering Tsinghua University Beijing 100084 China School of Materials Science & Engineering Beihang University Beijing 100191 China

High performance piezoelectric ceramics with high Curie temperatures(TC) are the bottle necks of relevant high temperature devices. In this study, the electrical performance and microstructure of Li and Mn codoped Aurivillius-type composite ceramics with a composition Ca_(0.99-x_Bi_(6.99+x)(Li Mn)_(0.01) Nb Ti_5O_(24)(x = 0–0.8) were systematically investigated. The results indicated that uniform intergrowth structure with a lattice similar to that of the end member CBT could be formed at a low x value(x < 0.4). Phase separation occurred when more A-site Ca^(2+) ions were replaced by Bi^(3+) ions. Nevertheless, all composite samples showed d_(33) values about 2 to 3 times of that of the constituent phase Ca Bi_4Ti_4O_(15) and Bi_3 Ti NbO_9 with still a high depolarization temperature. The performance of the samples was found to be related to the density and larger lattice distortion along the polarization a axis. The results also demonstrated that formation of the compound system was an effective way in improving the performance of Aurivillius-type high TC piezoelectric ceramics.

关键词： piezoelectric ceramics Curie temperature ferroelectricity dielectric properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Development and calibration of heat transfer coefficient sensor for rotational state

引用

航空动力学报 2011年第12期26卷 2684-2690页

作者： QUAN Yong-kai XU guo-qiang LUO Xiang ZHANG Da （School of Jet Propulsion Beijing University of Aeronautics and Astronautics Beijing 100000 China

A novel heat transfer coefficient sensor is introduced and the design,manufacture,and calibration are *** intended application of this instrument was on a high rotational speed test *** the experiments,the heat transfer coefficient sensor was calibrated under static state and rotational state *** calibration under the static state was accomplished in a pipe: the inside diameter(ID) was 0.048m and the total length was 4m,the distance between the sensor and the inlet of the pipe was 3.5m;the standard value was measured using a self-made *** calibration under the rotational state was accomplished using a rotating disc: the diameter and thickness of the stainless disc were 800mm and 25mm,respectively;the sensor was installed at the location of r=250mm;the rotating disc driven by a 30kW direct current motor can supply the maximum rotational speed of 3000r/*** standard value under rotational state was provided by an approximate empirical *** results show that the designed sensor can measure heat transfer coefficient directly under rotational state and static state with good accuracy and stability;the correlation factor of K are constant under static state and rotational state.

关键词： rotational state steady method heat transfer coefficient sentor calibration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Earth-abundant Zn-dipyrrin chromophores for efficient CO2 photoreduction

引用

National Science Review 2024年第6期11卷 214-222页

作者： Song guo Fu-Gui Zeng Xiao-Di Li kai-kai Chen Ping Wang Tong-Bu Lu Zhi-Ming Zhang Institute for New Energy Materials and Low Carbon Technologies School of Materials Science& Engineering Tianjin University of Technology

The development of strong sensitizing and Earth-abundant antenna molecules is highly desirable for CO2reduction through artificial photosynthesis. Herein, a library of Zn–dipyrrin complexes（Z-1-Z-6） are rationally designed via precisely controlling their molecular configuration to optimize strong sensitizing Earth-abundant photosensitizers. Upon visible-light excitation, their special geometry enables intramolecular charge transfer to induce a charge-transfer state, which was first demonstrated to accept electrons from electron donors. The resulting long-lived reduced photosensitizer was confirmed to trigger consecutive intermolecular electron transfers for boosting CO2-to-CO conversion. Remarkably, the Earth-abundant catalytic system with Z-6 and Fe-catalyst exhibits outstanding performance with a turnover number of >20 000 and 29.7% quantum yield, representing excellent catalytic performance among the molecular catalytic systems and highly superior to that of noble-metal photosensitizer Ir（ppy）2（bpy）+under similar conditions. Experimental and theoretical investigations comprehensively unveil the structure–activity relationship, opening up a new horizon for the development of Earth-abundant strong sensitizing chromophores for boosting artificial photosynthesis.

关键词： Zn complex photocatalysis CO2 reduction charge transfer photosensitizer

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Reentry Attitude Tracking Control for Hypersonic Vehicle with Reaction Control Systems via Improved Model Predictive Control Approach

引用

Computer Modeling in Engineering & Sciences 2020年第1期122卷 131-148页

作者： kai Liu Zheng Hou Zhiyong She Jian guo 无 School of Aeronautics and Astronautics Dalian University of TechnologyDalian116024China Key Laboratory of Advanced Technology for Aerospace Vehicles Dalian116024China Beijing Institute of Aerospace Technology Beijing100074China

This paper studies the reentry attitude tracking control problem for hypersonic vehicles(HSV)equipped with reaction control systems(RCS)and aerodynamic *** attitude dynamical model of the hypersonic vehicles is established,and the simplified longitudinal and lateral dynamic models are obtained,***,the compound control allocation strategy is provided and the model predictive controller is designed for the pitch ***,considering the complicated jet interaction effect of HSV during RCS is working,an improved model predictive control approach is presented by introducing the online parameter estimation of the jet interaction coefficient for dealing with the uncertainty and ***,considering the strong coupling effect between the yaw channel and roll channel,a coupled model predictive controller is designed by introducing the feedback of sideslip angle into the roll control channel to eliminate the coupling ***,the comparison simulations using the classical control method,MPC and IMPC approach are given to demonstrate the effectiveness and efficiency of the presented IMPC scheme.

关键词： Hypersonic vehicle reentry attitude control mode predictive control jet interference factor reaction control systems

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Discretization of Preisach hysteresis model

引用

Journal of Central South University 2015年第12期22卷 4724-4730页

作者：安凯蔡国平 Shandong Aerospace Electro-technology Institute Department of Engineering Mechanics Shanghai Jiaotong University

In order to reduce the partial derivative errors in Preisach hysteresis model caused by inaccurate experimental data,the concept and correlative method of discretization of Preisach hysteresis model are proposed,the essential of which is to centralize the distribution density of Preisach hysteresis model in local region as an integral,which is defined as the weight of a certain point in that *** the input composed of an ascending segment and a descending segment,a method to determine the initial weights together with an additional method to determine present weights is given according to the number of input ascending *** the number of input ascending segments increases,the weights of the corresponding points in updating rectangle are updated by adding the initial weights of corresponding points.A prominent advantage of discrete Preisach hysteresis model is its memory *** advantage of discrete Preisach hysteresis model is that there is no function in the model,and thus,it can be expediently operated using a *** generalizing the above updating rectangle method to the continuous Preisach hysteresis model,identification method of distribution density can be given as well.

关键词： hysteresis discretization distribution density output

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：