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Multi-Head Attention Enhanced Parallel Dilated Convolution and Residual Learning for Network Traffic Anomaly Detection

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Computers, Materials & Continua 2025年第2期82卷 2159-2176页

作者： Guorong Qi Jian Mao kai huang Zhengxian You Jinliang Lin College of Computer Engineering Jimei UniversityXiamen361021China Xiamen Jikuai Technology Co. Ltd.Xiamen361000China

Abnormal network traffic, as a frequent security risk, requires a series of techniques to categorize and detect it. Existing network traffic anomaly detection still faces challenges: the inability to fully extract local and global features, as well as the lack of effective mechanisms to capture complex interactions between features;Additionally, when increasing the receptive field to obtain deeper feature representations, the reliance on increasing network depth leads to a significant increase in computational resource consumption, affecting the efficiency and performance of detection. Based on these issues, firstly, this paper proposes a network traffic anomaly detection model based on parallel dilated convolution and residual learning (Res-PDC). To better explore the interactive relationships between features, the traffic samples are converted into two-dimensional matrix. A module combining parallel dilated convolutions and residual learning (res-pdc) was designed to extract local and global features of traffic at different scales. By utilizing res-pdc modules with different dilation rates, we can effectively capture spatial features at different scales and explore feature dependencies spanning wider regions without increasing computational resources. Secondly, to focus and integrate the information in different feature subspaces, further enhance and extract the interactions among the features, multi-head attention is added to Res-PDC, resulting in the final model: multi-head attention enhanced parallel dilated convolution and residual learning (MHA-Res-PDC) for network traffic anomaly detection. Finally, comparisons with other machine learning and deep learning algorithms are conducted on the NSL-KDD and CIC-IDS-2018 datasets. The experimental results demonstrate that the proposed method in this paper can effectively improve the detection performance.

关键词： Network traffic anomaly detection multi-head attention parallel dilated convolution residual learning

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A novel flexible nerve guidance conduit promotes nerve regeneration while providing excellent mechanical properties

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Neural Regeneration Research 2025年第7期20卷 2084-2094页

作者： Tong Li Quhan Cheng Jingai Zhang Boxin Liu Yu Shi Haoxue Wang Lijie huang Su Zhang Ruixin Zhang Song Wang Guangxu Lu Peifu Tang Zhongyang Liu kai Wang Department of Orthopedics the Fourth Medical Center of Chinese PLA General HospitalBeijingChina Department of Training and Sports Medicine Characteristic Medical Center of Chinese People’s Armed Police ForceTianjinChina Medical School of Chinese PLA BeijingChina Key Laboratory of Bioactive Materials for the Ministry of Education College of Life SciencesNankai UniversityTianjinChina Department of Orthopedics Tianjin HospitalTianjinChina Department of Rehabilitation Medicine Er Quan Hospital of PAPWuxiJiangsu ProvinceChina

Autografting is the gold standard for surgical repair of nerve defects>5 mm in length;however,autografting is associated with potential complications at the nerve donor *** an alternative,nerve guidance conduits may be *** ideal conduit should be flexible,resistant to kinks and lumen collapse,and provide physical cues to guide nerve *** designed a novel flexible conduit using electrospinning technology to create fibers on the innermost surface of the nerve guidance conduit and employed melt spinning to align ***,we prepared disordered electrospun fibers outside the aligned fibers and helical melt-spun fibers on the outer wall of the electrospun fiber *** presence of aligned fibers on the inner surface can promote the extension of nerve cells along the *** helical melt-spun fibers on the outer surface can enhance resistance to kinking and compression and provide *** novel conduit promoted nerve regeneration and functional recovery in a rat sciatic nerve defect model,suggesting that it has potential for clinical use in human nerve injuries.

关键词： aligned fibers anti-kinking helical fibers nerve guidance conduit nerve regeneration peripheral nerve injury topological guidance

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Insights on Peripheral Blood Biomarkers for Parkinson’s Disease

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生物化学与生物物理进展 2025年第1期52卷 72-87页

作者：刘经凯 LI Yu-Meng LIU Jing-kai CHEN Zi-xuan DENG Yu-Lin Beijing Key Laboratory for the Separation and Analysis of Biomedical Components School of Medical TechnologyBeijing Institute of TechnologyBeijing 100081China

Parkinson’s disease(PD)is a common neurodegenerative disorder with profound impact on patients’quality of life and long-term health,and early detection and intervention are particularly *** recent years,the search for precise and reliable biomarkers has become one of the key strategies to effectively address the clinical challenges of *** this paper,we systematically evaluated potential biomarkers,including proteins,metabolites,epigenetic markers,and exosomes,in the peripheral blood of PD *** markers are one of the main directions of biomarker research in *** particular,α‑synuclein and its phosphorylated form play a key role in the pathological process of *** has been shown that aggregation ofα-synuclein may be associated with pathologic protein deposition in PD and may be a potential marker for early diagnosis of *** terms of metabolites,uric acid,as a metabolite,plays an important role in oxidative stress and neuroprotection in *** has been found that changes in uric acid levels may be associated with the onset and progression of PD,showing its potential as an early diagnostic *** markers,such as DNA methylation modifications and miRNAs,have also attracted much attention in Parkinson’s disease *** in these markers may affect the expression of PD-related genes and have an important impact on the onset and progression of the disease,providing new research perspectives for the early diagnosis of *** addition,exosomes,as a potential biomarker carrier for PD,are able to carry a variety of biomolecules involved in intercellular communication and pathological *** have shown that exosomes may play an important role in the pathogenesis of PD,and their detection in blood may provide a new breakthrough for early *** has been shown that exosomes may play an important role in the pathogenesis of PD,and their detection in blood may provide new breakthroughs in early *** summary,through

关键词： Parkinson’s disease peripheral blood biomarkers early diagnosis

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New scoring system for the evaluation obstructive degrees based on computed tomography for obstructive colorectal cancer

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World Journal of Gastrointestinal Oncology 2025年第3期17卷 122-132页

作者： Xin-Chang Shang-Guan Jun-Rong Zhang Chao-Nan Lin Shuai Chen Yong Wei Wen-xuan Chen Lin Pan Li-Qin huang Shao-Hua Zheng Xian-Qiang Chen Department of Emergency Surgery Fujian Medical University Union HospitalFuzhou 350001Fujian ProvinceChina College of Physics and Information Engineering Fuzhou UniversityFuzhou 350001Fujian ProvinceChina

BACKGROUND The degree of obstruction plays an important role in decision-making for obstructive colorectal cancer(OCRC).The existing assessment still relies on the colorectal obstruction scoring system(CROSS)which is based on a comprehensive analysis of patients’complaints and eating *** data collection relies on subjective descriptions and lacks objective ***,a scoring system for the evaluation of computed tomography-based obstructive degree(CTOD)is urgently required for *** To explore the relationship between CTOD and CROSS and to determine whether CTOD could affect the short-term and long-term *** Of 173 patients were *** was obtained using k-means,the ratio of proximal to distal obstruction,and the proportion of nonparenchymal areas at the site of *** was integrated with the CROSS to analyze the effect of emergency intervention on ***-term and long-term outcomes were compared between the *** CTOD severe obstruction(CTOD grade 3)was an independent risk factor[odds ratio(OR)=3.390,95%confidence interval(CI):1.340-8.570,P=0.010]via multivariate analysis of short-term outcomes,while CROSS grade was *** the CTOD-CROSS grade system,for the non-severe obstructive(CTOD 1-2 to CROSS 1-4)group,the complication rate of emergency interventions was significantly higher than that of non-emergency interventions(71.4%vs 41.8%,P=0.040).The postoperative pneumonia rate was higher in the emergency intervention group than in the non-severe obstructive group(35.7%vs 8.9%,P=0.020).However,CTOD grade was not an independent risk factor of overall survival and progression-free *** CTOD was useful in preoperative decision-making to avoid unnecessary emergency interventions and complications.

关键词： Obstructive colorectal cancer Scoring system Computed tomography-based obstructive degree Colorectal obstruction scoring system Emergency intervention

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窟野河流域次降雨事件下水沙变化特征及其输移过程

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水土保持研究 2025年第2期32卷 52-60页

作者：杨晨佘冬立黄萱河海大学农业科学与工程学院南京211100

[目的]深入分析黄土高原粗沙区流域次降雨事件尺度下水沙动态变化特征及其输移过程,为黄土高原粗沙区流域的水沙管理和调控提供重要科学依据。[方法]以黄土高原中游粗沙多沙区窟野河流域为对象,收集2006—2019年间的160场次降雨事件水... 详细信息

[目的]深入分析黄土高原粗沙区流域次降雨事件尺度下水沙动态变化特征及其输移过程,为黄土高原粗沙区流域的水沙管理和调控提供重要科学依据。[方法]以黄土高原中游粗沙多沙区窟野河流域为对象,收集2006—2019年间的160场次降雨事件水沙数据。通过运用方差分析、水沙关系曲线、滞后分析等方法,比较位于窟野河及其子流域次降雨事件下产流输沙特征,构建了各流域次降雨事件尺度下水沙关系曲线,分析了水沙滞后关系及滞后指数的空间差异,以揭示次降雨尺度下窟野河流域的水沙输移过程。[结果](1)4个流域径流相关参数无显著差异,但泥沙相关参数差异显著;(2)位于窟野河上游东部的新庙流域水沙相关性强,表征外界人为干扰的参数(a)最大,位于上游西部的王道恒塔流域泥沙浓度低,水沙相关性弱,表征河流本身输沙能力的参数(b)最大;(3)新庙、王道恒塔和温家川3个流域的主要滞后模式为逆时针型,泥沙来源于上游区域,且高含沙降雨事件的滞后系数(HI)平均值多为负;而神木流域的主要滞后模式为“8”字型,指示泥沙来源相对接近流域出口,且高含沙降雨事件的HI平均值多为正。[结论]窟野河嵌套流域次降雨事件尺度下水沙变化空间差异显著,泥沙输移过程复杂,不同子流域滞后模式揭示了泥沙来源和输移机制的空间异质性。

关键词：次降雨事件尺度输移过程水沙关系滞后分析

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飞机轮胎-湿滑道面相互作用SPH算法仿真分析

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北京航空航天大学学报 2025年第1期51卷 53-62页

作者：蔡靖黄钰岱李琪李岳戴轩中国民航大学交通科学与工程学院天津300300

针对飞机在湿滑道面上的滑水问题,采用光滑粒子流体动力学(SPH)算法建立了飞机轮胎-湿滑道面有限元模型,与流固耦合算法(CEL)模型进行对比,显示了SPH算法的优越性,进而分析了不同轮胎速度及水膜厚度对轮胎与湿滑道面相互作用的影响规律... 详细信息

针对飞机在湿滑道面上的滑水问题,采用光滑粒子流体动力学(SPH)算法建立了飞机轮胎-湿滑道面有限元模型,与流固耦合算法(CEL)模型进行对比,显示了SPH算法的优越性,进而分析了不同轮胎速度及水膜厚度对轮胎与湿滑道面相互作用的影响规律。结果表明,SPH模型得到的临界滑水速度与CEL模型结果相差不超过5%;舰首波、侧向羽流等流体特征更为明显立体;平均运算效率较CEL模型提高36.5%。利用SPH模型分析可得,道面支撑力随轮胎速度增加呈先平缓下降再急速下降的趋势,水膜厚度为3~13 mm时,急速下降段所在轮胎速度区间为170~260 km/h,基本处于A320飞机的着陆滑跑速度范围内,应增强对飞机滑水事故风险的防范;位移阻力随着轮胎速度增加呈先增大后减小的趋势,且在轮胎达到临界滑水速度时取得最大值,进而提出利用位移阻力最大值确定临界滑水速度的方法;侧向羽流最大溅水高度随轮胎速度增加呈先升高后降低的趋势,在接近临界滑水速度时达到最大值;舰首波最大溅水高度低于侧向羽流最大溅水高度,且随轮胎速度增加而降低,达到临界滑水速度时舰首波接近消失,2种溅水特征的最大溅水高度值均低于A320飞机发动机的最小离地高度0.680 m,不会对发动机产生影响。

关键词：交通运输工程轮胎-道面相互作用光滑粒子流体动力学算法临界滑水速度道面支撑力位移阻力溅水高度

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兰坪主要铅锌矿复垦区氮循环相关细菌群落特征及其与土壤的响应

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环境科学 2025年第1期46卷 399-408页

作者：黄泽凯刀承娇马鹏翔李博阎凯云南农业大学资源与环境学院昆明650201

氮循环对土壤生态系统元素循环具有重要影响,理清氮循环微生物的关键环境因素对矿区生态恢复起着至关重要的作用.功能菌群可以通过参与矿区土壤元素生物地球化学循环,调控植被生长,有益于矿区复垦.兰坪铅锌矿是亚洲最大的露天铅锌矿开采... 详细信息

氮循环对土壤生态系统元素循环具有重要影响,理清氮循环微生物的关键环境因素对矿区生态恢复起着至关重要的作用.功能菌群可以通过参与矿区土壤元素生物地球化学循环,调控植被生长,有益于矿区复垦.兰坪铅锌矿是亚洲最大的露天铅锌矿开采区,矿区土壤镉含量是云南省重金属含量背景值95.6~388.7倍,亟需开展矿区生态恢复.为了探究铅锌矿复垦区氮循环细菌与土壤的响应,以兰坪铅锌矿复垦区土壤样品为研究对象,采用16S rRNA高通量测序技术、共现网络分析、PCoA、Manteltest和随机森林揭示兰坪铅锌矿复垦区在不同养分梯度下对氮循环功能微生物类群的影响.结果表明,优势菌属均来自亚硝化单胞菌科(Nitrosomonadaceae)下的未标注到的物种.铅锌对铅锌矿区氮循环功能微生物影响有限,更多的是有机质(SOM)和pH的影响.铵态氮(NH_(4)^(+)-N)、硝态氮(NO_(3)^(-)-N)和pH分别是影响硝化作用、反硝化作用和固氮微生物的关键理化因子.

关键词：氮循环细菌铅锌矿复垦区高通量测序共现网络分析

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环钻手术、药物注射联合PDL治疗瘢痕疙瘩疗效评价

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中国麻风皮肤病杂志 2025年第1期41卷 33-36页

作者：林萱毛华荣庞凯临沂市高新医院皮肤科山东临沂276014

目的:探讨环钻手术、药物注射联合脉冲染料激光(PDL)治疗瘢痕疙瘩的临床疗效。方法:选取2022年1月至2023年6月我院皮肤科治疗的瘢痕疙瘩10例,采用环钻手术、药物注射(曲安奈德5 mL、5-氟尿嘧啶0.6 mL、2%利多卡因1 mL)联合脉冲染料激光... 详细信息

目的:探讨环钻手术、药物注射联合脉冲染料激光(PDL)治疗瘢痕疙瘩的临床疗效。方法:选取2022年1月至2023年6月我院皮肤科治疗的瘢痕疙瘩10例,采用环钻手术、药物注射(曲安奈德5 mL、5-氟尿嘧啶0.6 mL、2%利多卡因1 mL)联合脉冲染料激光治疗。结果:所有患者均完成临床治疗与随访,术后随访12个月,术区瘢痕平软,肤色与周边正常皮肤接近,疼痛、瘙痒等症状明显缓解或消失;治愈率80%,有效率90%,90%患者对治疗效果满意。结论:环钻手术配合药物注射加脉冲染料激光进行联合治疗是治疗瘢痕疙瘩安全有效的方法,患者满意度较高。

关键词：瘢痕疙瘩环钻手术药物注射 595脉冲染料激光

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Plasmon-induced local electric field improved hydrogen evolution reaction on Ag/Mo_(2)C nanosheets

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Nano Research 2025年第1期18卷 270-277页

作者： huangJingWei Li Xin Zi Jun Wu Xinli Wang Li Zhu Qiyou Wang Jianfu Han Junwei Fu Hongmei Li kai huang Yu Chen Min Liu School of Physics State Key Laboratory of Powder MetallurgyHunan Joint International Research Center for Carbon Dioxide Resource UtilizationCentral South UniversityChangsha 410083China School of Metallurgy and Environment Central South UniversityChangsha 410083China Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Nano-Institute Munich Faculty of PhysicsLudwig-Maxilimians-Universität MünchenMünchen 80539Germany Hunan Institute of Advanced Sensing and Information Technology Xiangtan UniversityXiangtan 411105China

Electrocatalytic water splitting offers a promising way for hydrogen production with near-zero ***,such as molybdenum carbides(Mo_(2)C),are promising materials for hydrogen evolution reaction(HER)but still suffer from poor intrinsic water activation ***,we developed a plasmon-induced local electric field(PILEF)strategy to solve this ***(Ag)nanoparticles decorated Mo_(2)C nanosheets(Ag/Mo_(2)C)were successfully prepared by electrostatic *** visible light excited the PILEF on Ag/Mo_(2)C remarkably reducing the activation energy by 92.7 kJ·mol^(-1)from 147.3 kJ·mol^(-1)of Mo_(2)C to 54.6 kJ·mol^(-1).As a result,the plasmonic Ag/Mo_(2)C significantly enhances~2.3-fold of the current density from 2.8 mA·cm^(-2)of Mo_(2)C to 6.5 mA·cm^(-2)at-3 V *** and reduces the overpotential by 104 mV from 403 mV of dark state to 299 mV of light state at the current density of 10 mA·cm^(-2),achieving better performance than reported *** research demonstrates that PILEF enhances HER activities,offering a potential strategy for boosting the intrinsic activities of catalysts.

关键词： sliver particles plasmon effect field effect hydrogen evolution reaction(HER) electrocatalysis

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Histone H4K8hib modification promotes gene expression and regulates rice immunity

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Molecular Plant 2025年第1期18卷 9-13页

作者： Qiutao Xu xuan Ma Xuelu Wei Zhengting Chen Yuhang Duan Yuliang Ju Zhaoyun Wang Jing Chen Lu Zheng Xiaolin Chen Junbin huang Jisen Zhang Xiaoyang Chen State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of AgricultureGuangxi UniversityNanning 530004China College of Agriculture Ningxia UniversityYinchuan 750021China National Key Laboratory of Crop Genetic Improvement Huazhong Agricultural UniversityWuhan 430070China State Key Laboratory of Agricultural Microbiology Huazhong Agricultural UniversityWuhan 430070China Anhui Province Key Laboratory of Crop Integrated Pest Management Anhui Agricultural UniversityHefei 230036China

Dear Editor,Histones undergo various post-translational modifications essential for transcription,DNA replication,repair,and other cellular processes(Li et al.,2018).While histone methylation and acetylation are well studied,emerging short-chain lysine acylations,such as crotonylation,succinylation,lactylation,acetoacetylation,and 2-hydroxyisobutyrylation(Khib)(Li et al.,2018;Lu et al.,2018;Zheng et al.,2021;Gao et al.,2023),are expanding the field of epigenetic *** these short-chain acylations,Khib has garnered recent attention as an evolutionarily conserved modification on histone proteins,extensively characterized in yeast and animals,where it plays a role in glucose response and virus infection(huang et al.,2017;Zhao et al.,2022).In plants,H4K8hib has been identified on histones,but its functions and the enzymes involved in its removal remain *** this study,we analyzed the H4K8hib modification profile in rice,exploring its role in the rice immune response and identifying the enzymes responsible for its removal.

关键词： immunity modification expanding

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