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Advanced manufacturing of dielectric metadevices

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Photonics Insights 2024年第2期3卷 31-70页

作者： Wenhong Yang Junxiao Zhou Din Ping tsai Shumin Xiao Key Lab of Micro-Nano Optoelectronic Information System Ministry of Industry and Information TechnologyGuangdong Provincial Key Laboratory of Semiconductor Optoelectronic Materials and Intelligent Photonic SystemsHarbin Institute of TechnologyShenzhenChina Department of Electrical Engineering City University of Hong KongHong KongChina The State Key Laboratory of Terahertz and Millimeter Waves City University of Hong KongHong KongChina Centre for Biosystems Neuroscienceand NanotechnologyCity University of Hong KongHong KongChina Pengcheng Laboratory ShenzhenChina

Metasurfaces,composed of two-dimensional nanostructures,exhibit remarkable capabilities in shaping wavefronts,encompassing phase,amplitude,and *** unique proficiency heralds a transformative paradigm shift in the domain of next-generation optics and photonics,culminating in the development of flat and ultrathin optical *** noteworthy is the all-dielectric-based metasurface,leveraging materials such as titanium dioxide,silicon,gallium arsenide,and silicon nitride,which finds extensive application in the design and implementation of high-performance optical devices,owing to its notable advantages,including a high refractive index,low ohmic loss,and ***,the remarkable growth in nanofabrication technologies allows for the exploration of new methods in metasurface fabrication,especially through wafer-scale nanofabrication technologies,thereby facilitating the realization of commercial applications for *** review provides a comprehensive overview of the latest advancements in state-of-the-art fabrication technologies in dielectric metasurface *** technologies,including standard nanolithography[e.g.,electron beam lithography(EBL)and focused ion beam(FIB)lithography],advanced nanolithography(e.g.,grayscale and scanning probe lithography),and large-scale nanolithography[e.g.,nanoimprint and deep ultraviolet(DUV)lithography],are utilized to fabricate highresolution,high-aspect-ratio,flexible,multilayer,slanted,and wafer-scale all-dielectric metasurfaces with intricate ***,we conclude with a perspective on current cutting-edge nanofabrication technologies.

关键词： dielectric meta-devices meta-optics metasurface nanofabrication nanotechnology nanophotonics large/waferscale nanofabrication

FAST Observations of Four Comets to Search for the Molecular Line Emissions between 1.0 and 1.5 GHz Frequencies

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Research in Astronomy and Astrophysics 2024年第10期24卷 130-140页

作者： Long-Fei Chen Chao-Wei tsai Jian-Yang Li Bin Yang Di Li Yan Duan Chih-Hao Hsia Zhichen Pan Lei Qian Donghui Quan Xue-Jian Jiang Xiaohu Li Ruining Zhao Pei Zuo School of Physics and Electronic Science Guizhou Normal UniversityGuiyang 550025China Guizhou Provincial Key Laboratory of Radio Astronomy and Data Processing Guiyang 550025China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311100China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Key Laboratory of Radio Astronomy and Technology Chinese Academy of SciencesBeijing 100101China School of Atmospheric Sciences Sun Yat-sen UniversityZhuhai 519082China Núcleo de Astronomía Facultad de Ingenieríay CienciasUniversidad Diego PortalesChile Department of Astronomy College of Physics and Electronic EngineeringQilu Normal UniversityJinan 250200China Department of Electronic and Optical Engineering Space Engineering UniversityBeijing 101416China Laboratory for Space Research Faculty of ScienceThe University of Hong KongHong Kong(SAR)China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China CAS Key Laboratory of Optical Astronomy National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China School of Astronomy and Space Sciences University of Chinese Academy of SciencesBeijing 100049China

We used the Five-hundred-meter Aperture Spherical radio Telescope(FAST)to search for the molecular emissions in the L-band between 1.0 and 1.5 GHz toward four comets,C/2020 F3(NEOWISE),C/2020 R4(ATLAS),C/2021 A1(Leonard),and 67P/Churyumov-Gerasimenko during or after their perihelion *** of molecular transition lines fall in this low-frequency range,many attributed to complex organic or prebiotic *** conducted a blind search for the possible molecular lines in this frequency range in those comets and could not identify clear signals of molecular emissions in the *** several molecules have been detected at high frequencies of greater than100 GHz in comets,our results confirm that it is challenging to detect molecular transitions in the L-band frequency *** non-detection of L-band molecular lines in the cometary environment could rule out the possibility of unusually strong lines,which could be caused by the masers or non-LTE *** the line strengths are predicted to be weak,for FAST,using the ultra-wide bandwidth receiver and improving the radio frequency interference environments would enhance the detectability of those molecular transitions at low frequencies in the future.

关键词： astrochemistry ISM:molecules comets:general line:identification

Effect of nocturia in patients with different severity of obstructive sleep apnea on polysomnography: A retrospective observational study

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Asian Journal of Urology 2024年第3期11卷 486-496页

作者： Chin-Heng Lu Hung-Min Chang Kuang-Hsi Chang Yen-Chuan Ou Chao-Yu Hsu Min-Che Tung Frank Cheau-Feng Lin Stella Chin-Shaw tsai Division of Urology Department of SurgeryTungs’Taichung Metroharbor HospitalTaichungTaiwanChina Rong Hsing Research Center for Translational Medicine Chung Hsing UniversityTaichungTaiwanChina College of Life Sciences Chung Hsing UniversityTaichungTaiwanChina Department of Otolaryngology Tungs’Taichung Metroharbor HospitalTaichungTaiwanChina Department of Medical Research Tungs’Taichung Metroharbor HospitalTaichungTaiwanChina General Education Center Jen-Teh Junior College of MedicineNursing and ManagementMiaoliTaiwanChina Graduate Institute of Biomedical Sciences China Medical UniversityTaichungTaiwanChina Department of Post-Baccalaureate Medicine College of MedicineChung Hsing UniversityTaichungTaiwanChina Department of Nursing Jen-Teh Junior College of MedicineNursing and ManagementMiaoliTaiwanChina Department of Surgery Chung Shan Medical UniversityTaichungTaiwanChina College of Medicine Chung Shan Medical UniversityTaichungTaiwanChina

Patients with suspected OSA were examined using *** were divided into two groups based on the presence of *** was defined as a patient who needed to void at least *** index(AHI)was employed to classify patients according to degrees of severity:AHI<5 events/h,5 events/hAHI<15 events/h,15 events/hAHI<30 events/h,and AHI30 events/h,defined as normal,mild OSA,moderate OSA,and severe OSA,*** variables,PSG parameters,International Prostate Symptom Scores(IPSSs),and quality of life scores due to urinary symptoms were ***:In total 140 patients,114 patients had OSA(48 had mild OSA;34 had moderate OSA;and 32 had severe OSA)and 107 patients had *** total IPSS was significantly higher in nocturia patients in all groups except the group of severe OSA *** the increasing severity of OSA,more correlated factors related to nocturia were *** mild OSA patients,nocturia related to increased age(p=0.025),minimum arterial blood oxygenation saturation(p=0.046),and decreased AHI of non-rapid eye movement(p=0.047),AHI of total sleep time(p=0.010),and desaturation index(p=0.012).In moderate OSA patients,nocturia related to increased age(p<0.001),awake time(p=0.025),stage 1 sleep(p=0.033),and sleep latency(p=0.033),and decreased height(p=0.044),weight(p=0.025),and sleep efficiency(p=0.003).In severe OSA patients,nocturia related to increased weight(p=0.011),body mass index(p=0.009),awake time(p=0.008),stage 1 sleep(p=0.040),arousal number(p=0.030),arousal index(p=0.013),periodic limb movement number(p=0.013),and periodic limb movement index(p=0.004),and decreased baseline arterial blood oxygenation saturation(p=0.046).Conclusion:Our study revealed that there were more correlated factors related to nocturia with increasing severity of *** study helps in clinical education and treatment for OSA patients with different severity.

关键词： Nocturia Obstructive sleep apnea Polysomnography Apneaehypopnea index International Prostate Symptom Score

Assessment and Visualization of Ki67 Heterogeneity in Breast Cancers through Digital Image Analysis

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Advances in Breast Cancer Research 2024年第2期13卷 11-26页

作者： Chien-Hui Wu Min-Hsiang Chang Hsin-Hsiu tsai Yi-Ting Peng Department of Anatomical Pathology Far Eastern Memorial Hospital New Taipei AI Lab Quanta Computer Inc. Taoyuan

The Ki67 index (KI) is a standard clinical marker for tumor proliferation;however, its application is hindered by intratumoral heterogeneity. In this study, we used digital image analysis to comprehensively analyze Ki67 heterogeneity and distribution patterns in breast carcinoma. Using Smart Pathology software, we digitized and analyzed 42 excised breast carcinoma Ki67 slides. Boxplots, histograms, and heat maps were generated to illustrate the KI distribution. We found that 30% of cases (13/42) exhibited discrepancies between global and hotspot KI when using a 14% KI threshold for classification. Patients with higher global or hotspot KI values displayed greater heterogenicity. Ki67 distribution patterns were categorized as randomly distributed (52%, 22/42), peripheral (43%, 18/42), and centered (5%, 2/42). Our sampling simulator indicated analyzing more than 10 high-power fields was typically required to accurately estimate global KI, with sampling size being correlated with heterogeneity. In conclusion, using digital image analysis in whole-slide images allows for comprehensive Ki67 profile assessment, shedding light on heterogeneity and distribution patterns. This spatial information can facilitate KI surveys of breast cancer and other malignancies.

关键词： Ki67 Heterogeneity Breast Cancer Digital Image Analysis

Discussion of the Composition of Jaboticaba in Different Processes

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Food and Nutrition Sciences 2024年第1期15卷 101-112页

作者： Ching-Hu tsai Yi-Chun Lin Chih-Ta Liu Yo-Ju Chen Department of Long-Term Care Kang Ning University Taipei Department of Respiratory Therapy En Chu Kong Hospital New Taipei City Department of Thoracic Surgery Division En Chu Kong Hospital New Taipei City

This study discusses the composition analysis and comparison of Jaboticaba under different processing conditions for fermented liquid, jam, fruit powder, and fruit vinegar. The differences and comparison of the contents of total polyphenols, anthocyanins, resveratrol, superoxide dismutase, small molecular peptides and ellagic acid in their products were analyzed. After analysis and comparison of results, the content of total polyphenols was found to be the highest 44.82 ± 0.89 (mg/g) after being fermented directly from fresh fruit. The fresh fruit was dried at low temperature and ground into powder, with a maximum ellagic acid content of 12.799 ± 0.12 (mg/g). Fresh fruit was then made into jam, with the highest anthocyanin content of 57.39 ± 1.20 (mg/g). The fruit vinegar was produced by fermentation. Except for the content of small molecule peptides, which was similar to the content of fermentation broth and fruit powder, they were 20.63 ± 1.61, 23.84 ± 2.51 and 20.52 ± 1.21 (mg/g), and the rest of the composition was not as good as other samples. In the fresh fruit fermentation broth samples, resveratrol was produced and detected, and its content was 2.14 (mg/L), while it was not detected in other samples, and a superoxide dismutase (SOD)-like enzyme was detected in the fresh fruit fermentation broth. The highest activity was 49002.5 units/mL. Jaboticaba is prepared using a fermentation broth processing method with fresh fruit, and its total polyphenol content is higher than that of fruit powder, jam, and fruit vinegar. The commercial value of Jaboticaba and the establishment of composition content data are relatively improved, which is more promising for the future.

关键词： Jaboticaba Total Polyphenols Anthocyanins Resveratrol Small Molecule Peptides

Molecular Oxygen Abundance in Galactic Massive Star Formation Regions Based on SWAS Observations

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Research in Astronomy and Astrophysics 2024年第9期24卷 83-98页

作者： Bing-Ru Wang Di Li Paul F.Goldsmith Jingwen Wu Chao-Wei tsai Donghui Quan Xia Zhang Junzhi Wang Gary J.Melnick Jin-Zeng Li Gary A.Fuller Jinjin Xie National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Tsinghua University Beijing 100084China University of Chinese Academy of Sciences Beijing 100049China Research Center for Astronomical Computing Zhejiang LaboratoryHangzhou 311100China Jet Propulsion Laboratory California Institute of TechnologyPasadenaCA 91109USA Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Xinjiang Astronomical Observatory Chinese Academy of SciencesUrumqi 830011China Guangxi Key Laboratory for Relativistic Astrophysics School of Physical Science and TechnologyGuangxi UniversityNanning 530004China Center for Astrophysics Harvard&Smithsonian60 Garden StreetMS 66CambridgeMA 02138USA Jodrell Bank Center for Astrophysics Department of Physics&AstronomyUniversity of ManchesterOxford RoadManchesterM139PLUK I.Physikalisches Institut University of CologneZülpicher Str.7750937 KölnGermany

Molecular oxygen abundance is a key parameter in understanding the chemical network of the interstellar *** estimate the molecular oxygen column density and abundance for a sample of Galactic massive star formation regions based on observations from the Submillimiter Wave Astronomy Satellite(SWAS)*** obtained an averaged O_(2)spectrum based on this sample using the(SWAS)survey data(O_(2),487.249 GHz,N=3-1,J=3-2).No emission or absorption feature is seen around the supposed central velocity with a total integration time of t_(total)=8.67×10^(3)hr and an rms noise per channel of 1.45 m *** a kinetic temperature T_(kin)=30 K,we derive the 3σupper limit of the O_(2)column density to be 3.3×10^(15)cm^(-2),close to the lowest values reported in Galactic massive star formation regions in previous *** corresponding O_(2)abundance upper limit is6.7×10^(-8),lower than all previous results based on SWAS observations and is close to the lowest reported value in massive star formation *** a galactic scale,our statistical results confirm a generally low O_(2)abundance for Galactic massive star formation *** abundance is also lower than results reported in extragalactic sources.

关键词： ISM:molecules galaxies:abundances ISM:lines and bands Galaxy:abundances

Half-precessional cycle revealed by environment magnetism of stalagmite in Shizhu Cave from southwestern China during the Last Glacial

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Journal of Earth Science 2024年

作者： Huihui Yang Yu-Min Chou Xiuyang Jiang Wenyue Xia Hai Li Yi Zhong Jingyu Zhang Yaoqi He tsai-Luen Yu Qingsong Liu Chuan-Chou Shen College of Tourism and Air Service， Guizhou Minzu University Research Center for Future Earth， Taiwan University Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou) School of Environment， Harbin Institute of Technology High-Precision Mass Spectrometry and Environment Change Laboratory (HISPEC)， Department of Geosciences， Taiwan University Key Laboratory of Humid Subtropical Eco-Geographical Processes， College of Geography Science， Fujian Normal University Center for Marine Magnetism (CM2)， Department of Ocean Science and Engineering， Southern University of Science and Technology

The environmental magnetic proxies of stalagmites hold significant potential for reconstructing regional hydroclimate changes by revealing the content and grain size of magnetic particles within stalagmites. In this study， we present the contents and grain sizes of magnetic particles within a stalagmite SZ-1， from Shizhu Cave in southwestern China from 70.4 to 22.3 thousand years ago (ka) during the last glacial period. Specifically， the parameters IRMsoft， soil-derived magnetic minerals， and ARM/SIRM (anhysteretic remanent magnetization/saturation isothermal remanent magnetization)， the ratio of fine magnetic particles to total ferrimagnetic particles preserved in stalagmite SZ-1， indicate the fluctuation of regional precipitation. Obvious half-precessional cycles are evident in these two proxies， indicating that hydroclimatic variations in southwestern China may predominantly arise from the heat and moisture transported from tropical oceans. These variations are likely influenced by shifts in the Intertropical Convergence Zone and fluctuations in the Asian summer monsoon.

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Extensive spectral tuning of the proton transfer emission from green to red via a rational derivatization of salicylideneaniline

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Chinese Chemical Letters 2012年第11期23卷 1279-1282页

作者： Hsing Yang tsai Sin kai Fang Kew Yu Chen Department of Chemical Engineering Feng Chia University

A series of salicylideneaniline derivatives 1a-lf were synthesized under mild condition in high yields, and characterized by ^1H NMR, HRMS, UV-vis and emission spectra. In solid and aprotic solvents 1a-1f exist mainly as E conformers that possess a sixmembered-ring hydrogen bond and undergo excited-state intramolecular proton transfer （ESIPT） reactions, resulting in a protontransfer tautomer emission. Depending on the electronic donor or acceptor strength of the substituent in either the HOMO or LUMO site, a broad tuning range of the emission from green （1c） to red （1a） has been achieved.

关键词： ESIPT Schiff bases Salicylideneaniline derivatives Db'T calculations

The Clumpy Structure of Five Star-bursting Dwarf Galaxies in the MaNGA Survey

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Research in Astronomy and Astrophysics 2024年第2期24卷 83-103页

作者： Mengting Ju Jun Yin Lei Hao Chenxu Liu Chao-Wei tsai Junfeng Wang Zhengyi Shao Shuai Feng Yu Rong Key Laboratory for Research in Galaxies and Cosmology Shanghai Astronomical ObservatoryChinese Academy of SciencesShanghai 200030China University of Chinese Academy of Sciences Beijing 100049China Key Lab for Astrophysics Shanghai 200034China South-Western Institute for Astronomy Research Yunnan UniversityKunming 650500China National Astronomical Observatories Chinese Academy of SciencesBeijing 100101China Institute for Frontiers in Astronomy and Astrophysics Beijing Normal UniversityBeijing 102206China Department of Astronomy Physics BuildingXiamen UniversityXiamenFujian 361005China College of Physics Hebei Normal UniversityShijiazhuang 050024China Hebei Key Laboratory of Photophysics Research and Application Shijiazhuang 050024China Department of Astronomy University of Science and Technology of ChinaHefei 230026China

The star-forming clumps in star-bursting dwarf galaxies provide valuable insights into understanding the evolution of dwarf *** this paper,we focus on five star-bursting dwarf galaxies featuring off-centered clumps in the Mapping Nearby Galaxies at Apache Point Observatory *** the stellar population synthesis software Fitting Analysis using Differential evolution Optimization,we obtain the spatially resolved distribution of the star formation history,which allows us to construct the g-band images of the five galaxies at different *** images can help us to probe the evolution of the morphological structures of these *** images of a stellar population older than 1 Gyr are typically smooth,images of a stellar population younger than 1 Gyr reveal significant clumps,including multiple clumps which appear at different locations and even different *** study the evolutionary connections of these five galaxies to other dwarf galaxies before their star-forming clumps appear,we construct the images of the stellar populations older than three age nodes,and define them to be the images of the"host"*** find that the properties such as the central surface brightness and the effective radii of the hosts of the five galaxies are in between those of dwarf ellipticals(dEs)and dwarf irregulars(dIrrs),with two clearly more similar to dEs and one more similar to *** the five galaxies,8257-3704 is particularly interesting,as it shows a previous starburst event that is not quite visible from its gri image,but only visible from images of the stellar population at a few hundred million *** star-forming clump associated with this event may have appeared at around 600 Myr ago and disappeared at around 40 Myr ago.

关键词： galaxies dwarf-galaxies evolution-galaxies formation-Galaxy structure