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Worst-Case Finish Time Analysis for DAG-Based Applications in the Presence of Transient Faults

Journal of Computer Science & Technology 2016年第2期31卷 267-283页

作者： Xiao-Tong Cui kai-jie wu Tong-Quan Wei Hsing-Mean Sha Key Laboratory of Dependable Service Computing in Cyber Physical Society Chongqing University Chongqing 400014 China College of Computer Science Chongqing University Chongqing 400044 China Department of Computer Science and Technology East China Normal University Shanghai 200241 China

Tasks in hard real-time systems are required to meet preset deadlines, even in the presence of transient faults and hence the analysis of worst-case finish time （WCFT） must consider the extra time incurred by re-executing tasks that were faulty. Existing solutions can only estimate WCFT and usually result in significant under- or over-estimation. In this work, we conclude that a sufficient and necessary condition of a task set experiencing its WCFT is that its critical task incurs all expected transient faults. A method is presented to identify the critical task and WCFT in O（IVI ＋ IEI） where IVI and IEI are the number of tasks and dependencies between tasks, respectively. This method finds its application in testing the feasibility of directed acyclic graph （DAG） based task sets scheduled in a wide variety of fault-prone multi-processor systems, where the processors could be either homogeneous or heterogeneous, DVS-capable or DVS-incapable, etc. The common practices, which require the same time complexity as the proposed critical-task method, could either underestimate the worst case by up to 25%, or overestimate by 13%. Based on the proposed critical-task method, a simulated-annealing scheduling algorithm is developed to find the energy efficient fault-tolerant schedule for a given DAG task set. Experimental results show that the proposed critical-task method wins over a common practice by up to 40% in terms of energy saving.

关键词： fault tolerance worst-case analysis simulated annealing energy conservation dynamic voltage scaling (DVS)

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PSA time to nadir as a prognostic factor of first-line docetaxel treatment in castration-resistant prostate cancer： evidence from patients in Northwestern China

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Asian Journal of Andrology 2018年第2期20卷 173-177页

作者： kai-jie wu Xin-Qi Pei Ge Tian Da-Peng wu Jin-Hai Fan Yu-Mei Jiang Da-Lin He Department of Urology The First Affiliated Hospital of Xi'an Jiaotong University Xi'an 710061 China

Docetaxel-based chemotherapy remains the first-line treatment for patients with metastatic castration-resistant prostate cancer （mCRPC） in China; however, the prognostic factors associated with effects in these patients are still controversial. In this study, we retrospectively reviewed the data from 71 eligible Chinese patients who received docetaxel chemotherapy from 2009 to 2016 in our hospital and experienced a reduction of prostate-specific antigen （PSA） level 〉50% during the treatment and investigated the potential role of time to nadir （TTN） of PSA. TTN was defined as the time from start of chemotherapy to the nadir of PSA level during the treatment. Multivariable Cox regression models and Kaplan-Meier analysis were used to predict overall survival （OS）. In these patients, the median of TTN was 17 weeks. Patients with TTN ≥17 weeks had a longer response time to chemotherapy compared to TTN 〈17 weeks （42.83 vs 21.50 weeks, P 〈 0.001）. The time to PSA progression in patients with TTN ：〉17 weeks was 11.44 weeks compared to 5.63 weeks when TTN was 〈17 weeks. We found several factors to be associated with OS, including TTN （hazard ratio [HR]. 3.937, 95% confidence interval [CI]： 1.502-10.309, P = 0.005）, PSA level at the diagnosis of cancer （HR： 4,337, 95% CI： 1.616-11.645, P= 0.004）, duration of initial androgen deprivation therapy （HR： 2.982, 95% CI： 1.104-8.045, P= 0.031）, neutrophil-to-lymphocyte ratio （HR： 3.963, 95% CI： 1.380-11.384, P = 0.011）, and total PSA response （Class 1 [〈0 response] compared to Class 2 [0-50% response], HR： 3.978, 95% CI： 1.278-12.387, P = 0.017）. In conclusion, TTN of PSA remains an important prognostic marker in predicting therapeutic outcome in Chinese population who receive chemotherapy for mCRPC and have 〉50% PSA remission.

关键词： castration-resistant prostate cancer chemotherapy docetaxel prostate-specific antigen survival time to nadir

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Festosterone regulates keratin 33B expression in rat penis growth through androgen receptor signaling

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Asian Journal of Andrology 2014年第6期16卷 817-823页

作者： Yan-Min Ma kai-jie wu Qiang Dang Qi Shi Yang Gao Peng Guo Shan Xu Xin-Yang Wang Da-Lin He Yong-Guang Gong Department of Urology First Affiliated Hospital of Medical School Xi'an Jiaotong University Oncology Research Lab Key Laboratory of Environment and Genes Related to Diseases Ministry of Education of the People's Republic of China Xi'an 710061 China

Androgen therapy is the mainstay of treatment for the hypogonadotropic hypogonadal micropenis because it obviously enhances penis growth in prepubescent microphallic patients. However, the molecular mechanisms of androgen treatment leading to penis growth are still largely unknown. To clarify this well-known phenomenon, we successfully generated a castrated male Sprague Dawley rat model at puberty followed by testosterone administration. Interestingly, compared with the control group, testosterone treatment stimulated a dose-dependent increase of penis weight, length, and width in castrated rats accompanied with a dramatic recovery of the pathological changes of the penis. Mechanistically, testosterone administration substantially increased the expression of androgen receptor （AR） protein. Increased AR protein in the penis could subsequently initiate transcription of its target genes, including keratin 33B （Krt33b）. Importantly, we demonstrated that KRT33B is generally expressed in the rat penis and that most KRT33B expression is cytoplasmic. Furthermore, AR could directly modulate its expression by binding to a putative androgen response element sequence of the Krt33b promoter. Overall, this study reveals a novel mechanism facilitating penis growth after testosterone treatment in precastrated prepubescent animals, in which androgen enhances the expression of AR protein as well as its target genes, such as Krt33b.

关键词： androgen receptor keratin 33B penis testosterone

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Scan-Based Attack on Stream Ciphers: A Case Study on eSTREAM Finalists

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Journal of Computer Science & Technology 2014年第4期29卷 646-655页

作者：邹敏辉马坤吴剀劼沙行勉 College of Computer Science Chongqing University Department of Electrical and Computer Engineering University of Illinois at Chicago Chicago IL 60607 U.S.A. IEEE Key Laboratory of Dependable Service Computing in Cyber Physical Society Chongqing UniversityMinistry of Education

Scan-based design for test （DFT） is a powerful and the most popular testing technique. However, while scan-based DFT improves test efficiency, it also leaves a side channel to the privacy information stored in the chip. This paper investigates the side channel and proposes a simple but powerful scan-based attack that can reveal the key and/or state stored in the chips that implement the state-of-the-art stream ciphers with less than 85 scan-out vectors.

关键词： scan-based attack stream cipher linear and non-linear feedback shift register scan-based design for test

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Relationships among androgen receptor CAG repeat polymorphism, sex hormones and penile length in Han adult men from China： a cross-sectional study

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Asian Journal of Andrology 2014年第3期16卷 478-481页

作者： Yan-Min Ma kai-jie wu Liang Ning Jin Zeng Bo Kou Hong-Jun Xie Zhen-Kun Ma Xin-Yang Wang Yong-Guang Gong Da-Lin He Department of Urology First Affiliated Hospital of Medical School Xi'an Jiaotong University Xi'an Oncology Research Lab Key Laboratory of Environment and Genes Related to Diseases Ministry of Education of the People's Republic of China Xi'an China.

This study aimed to investigate the correlations among androgen receptor （AR） CAG repeat polymorphism, sex hormones and penile length in healthy Chinese young adult men. Two hundred and fifty-three healthy men （aged 22.8 ± 3.1years） were enrolled. The individuals were grouped as CAG short （CAGs） if they harbored repeat length of 〈20 or as CAG long （CAGL） if their CAG repeat length was 〉20. Body height/weight, penile length and other parameters were examined and recorded by the specified physicians; CAG repeat polymorphism was determined by the polymerase chain reaction （PCR） method; and the serum levels of the sex hormones were detected by radioimmunoassay. Student＇s t-test or linear regression analysis was used to assess the associations among AR CAG repeat polymorphism, sex hormones and penile length. This investigation showed that the serum total testosterone （T） level was positively associated with the AR CAG repeat length （P = 0.01）; whereas, no significant correlation of T or AR CAG repeat polymorphism with the penile length was found （P = 0.593）. Interestingly, an inverse association was observed between serum prolactin （PRL） levels and penile length by linear regression analyses （β = -0.024, P = 0.039, 95% confidence interval （CI）： -0.047, 0）. Collectively, this study provides the first evidence that serum PRL, but not T or AR CAG repeat polymorphism, is correlated with penile length in the Han adult population from northwestern China.

关键词： androgen receptor CAG repeat testosterone prolactin penile length

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拉伸式3-D多涡卷混沌系统的设计及其在保密通信中的应用

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通信学报 2016年第12期37卷 142-155页

作者：马均澎王丽丹段书凯吴洁宁西南大学电子信息工程学院非线性电路与智能信息处理重庆市重点实验室重庆400715

基于典型的Chua式电路,提出了一种拉伸式多涡卷混沌系统。首先,通过系统的对称性、不变性、耗散性、系统平衡点和稳定性,分析了混沌的分维特性、时域波形、Lyapunov指数谱等基本的混沌动力学特性。其次,利用PSPICE实现了该系统的混沌电... 详细信息

基于典型的Chua式电路,提出了一种拉伸式多涡卷混沌系统。首先,通过系统的对称性、不变性、耗散性、系统平衡点和稳定性,分析了混沌的分维特性、时域波形、Lyapunov指数谱等基本的混沌动力学特性。其次,利用PSPICE实现了该系统的混沌电路。最后,结合Lyapunov稳定性原理,运用单向耦合法,探究了该混沌系统的同步性问题,并采用该方法有效地实现了特定信号的加密、解密。数值仿真与实验结果保持一致,进一步证实了该方法的可行性。

关键词： Chua电路保密通信多涡卷混沌吸引子电路实现

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Repetitive transcranial magnetic stimulation in Alzheimer’s disease:effects on neural and synaptic rehabilitation

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Neural Regeneration Research 2025年第2期20卷 326-342页

作者： Yi Ji Chaoyi Yang Xuerui Pang Yibing Yan Yue wu Zhi Geng Wenjie Hu Panpan Hu Xingqi wu kai Wang Department of Neurology The First Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina Anhui Province Key Laboratory of Cognition and Neuropsychiatric Disorders HefeiAnhui ProvinceChina Collaborative Innovation Center of Neuropsychiatric Disorders and Mental Health HefeiAnhui ProvinceChina Institute of Artificial Intelligence Hefei Comprehensive National Science CenterHefeiAnhui ProvinceChina Department of Psychology and Sleep Medicine The Second Affiliated Hospital of Anhui Medical UniversityHefeiAnhui ProvinceChina

Alzheimer’s disease is a neurodegenerative disease resulting from deficits in synaptic transmission and *** Alzheimer’s disease brain tends to be hyperexcitable and hypersynchronized,thereby causing neurodegeneration and ultimately disrupting the operational abilities in daily life,leaving patients *** transcranial magnetic stimulation is a cost-effective,neuro-modulatory technique used for multiple neurological *** the past two decades,it has been widely used to predict cognitive decline;identify pathophysiological markers;promote neuroplasticity;and assess brain excitability,plasticity,and *** has also been applied to patients with dementia,because it can yield facilitatory effects on cognition and promote brain recovery after a neurological ***,its therapeutic effectiveness at the molecular and synaptic levels has not been elucidated because of a limited number of *** study aimed to characterize the neurobiological changes following repetitive transcranial magnetic stimulation treatment,evaluate its effects on synaptic plasticity,and identify the associated *** review essentially focuses on changes in the pathology,amyloidogenesis,and clearance pathways,given that amyloid deposition is a major hypothesis in the pathogenesis of Alzheimer’s *** mechanisms associated with repetitive transcranial magnetic stimulation procedures and different pathways mediating gene transcription,which are closely related to the neural regeneration process,are also ***,we discuss the outcomes of animal studies in which neuroplasticity is modulated and assessed at the structural and functional levels by using repetitive transcranial magnetic stimulation,with the aim to highlight future directions for better clinical translations.

关键词： Alzheimer’s disease amyloid deposition apoptotic mechanisms biomarker neural regeneration neurodegeneration repetitive transcranial magnetic stimulation synaptic plasticity

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Association of stent thrombectomy and conventional treatment with neuroprotection, complications, anxiety, and depression in acute ischemic stroke patients

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World Journal of Psychiatry 2025年第1期15卷 72-82页

作者： kai-jie Yang Jia-Jian Huang Cai-Xia Xuan Department of Neurology Qinzhou Second People's HospitalQinzhou 535000Guangxi Zhuang Autonomous RegionChina

BACKGROUND Acute ischemic stroke(AIS)is an abrupt blood flow cessation to a specific brain region within a vascular zone,causing a subsequent decline in neurological *** thrombectomy is a recently established technique for treating *** provides the benefits of being a relatively simple and safe procedure,capable of partially enhancing a patient’s ***,some patients may experience endothelial damage and recurrent thrombosis,with clinical outcomes that are not always ***,the efficacy of this method remains *** To survey the association of stent thrombectomy vs standard treatment with neurological function protection,complications,and short-term prognosis in patients diagnosed with *** This study assigned 90 patients with AIS to the observation and control groups(n=45 patients)from December 2020 to December *** thrombectomy was conducted in the observation group,whereas routine treatment was provided to the control *** study assessed the therapeutic outcomes of two groups,including a comparison of their neurological function,living ability,anxiety and depression status,plaque area,serum inflammatory factors,serum Smur100βprotein,neuron-specific enolase(NSE),homocysteine(Hcy),and vascular endo-thelial ***,the incidence of complications was calculated and analyzed for each *** The total effective rate of treatment was 77.78%and 95.56%in the control and observation groups,*** 8 weeks of treatment,the scores on the National Institutes of Health Stroke Scale,Hamilton Anxiety Scale,and Hamilton Depression Scale decreased remarkably;the Barthel index increased remarkably,with better improvement effects of the scores in the observation group(P<0.05);total cholesterol,triglyceride,C-reactive protein,and plaque area lessened remarkably,with fewer patients in the observation group(P<0.05);S-100βprotein,NSE,and Hcy levels lessened remarkably,with fewer patients in

关键词： Stent thrombectomy Acute ischemic stroke Neurological function Complications Short-term prognosis

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Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： Mu-Hsien Lee Cheng-Hui Lin Chi-Huan wu Yung-Kuan Tsou kai-Feng Sung Sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

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Catalyst–Support Interaction in Polyaniline‑Supported Ni_(3)Fe Oxide to Boost Oxygen Evolution Activities for Rechargeable Zn‑Air Batteries

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Nano-Micro Letters 2025年第1期17卷 176-190页

作者： Xiaohong Zou Qian Lu Mingcong Tang jie wu Kouer Zhang Wenzhi Li Yunxia Hu Xiaomin Xu Xiao Zhang Zongping Shao Liang An Department of Mechanical Engineering The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control Jiangsu Collaborative Innovation Center of Atmospheric Environment and Equipment TechnologySchool of Environmental Science and TechnologyNanjing University of Information Science and TechnologyNanjing 210044People’s Republic of China Department of Chemistry The Chinese University of Hong KongMa Lin BuildingShatinHong Kong SAR 999077People’s Republic of China WA School of Mines:Minerals Energy and Chemical Engineering(WASM‑MECE)Curtin UniversityPerthWA 6102Australia Research Institute for Advanced Manufacturing The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China Research Institute for Smart Energy The Hong Kong Polytechnic UniversityHung HomKowloonHong Kong SARPeople’s Republic of China

Catalyst–support interaction plays a crucial role in improving the catalytic activity of oxygen evolution reaction(OER).Here we modulate the catalyst–support interaction in polyaniline-supported Ni_(3)Fe oxide(Ni_(3)Fe oxide/PANI)with a robust hetero-interface,which significantly improves oxygen evolution activities with an overpotential of 270 mV at 10 mA cm^(-2)and specific activity of 2.08 mA cm_(ECSA)^(-2)at overpotential of 300 mV,3.84-fold that of Ni_(3)Fe *** is revealed that the catalyst–support interaction between Ni_(3)Fe oxide and PANI support enhances the Ni–O covalency via the interfacial Ni–N bond,thus promoting the charge and mass transfer on Ni_(3)Fe *** the excellent activity and stability,rechargeable Zn-air batteries with optimum Ni_(3)Fe oxide/PANI are assembled,delivering a low charge voltage of 1.95 V to cycle for 400 h at 10 mA cm^(-2).The regulation of the effect of catalyst–support interaction on catalytic activity provides new possibilities for the future design of highly efficient OER catalysts.

关键词： Catalyst-support interaction Supported catalysts Heterointerface Oxygen evolution reaction Zn-air batteries

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