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World Journal of Clinical Cases 2021年第29期9卷 8820-8824页

作者： Gui-Qin Chen Yang Wu kai-fei zhao Rong-Shu Shi Department of Radiology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Intervention The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Implanted intravenous infusion port(IVAP)is indicated for patients undergoing chemotherapy,total parenteral nutrition and long-term antibiotic *** their complications,the rupture and migration of the catheter of an IVAP via internal jugular vein represents a very rare but potentially severe *** SUMMARY A 43-year-old woman was identified with a spontaneous fracture and migration of catheter of an IVAP via right internal jugular vein after adjuvant chemotherapy for left breast cancer.A computed tomography showed the fractured catheter of the IVAP in the pulmonary ***,we conducted an emergency procedure to remove the catheter fragment by a pigtail catheter combined with a gooseneck *** When the fractured catheter of an IVAP was detected,the special shape of the pigtail catheter in combination with the gooseneck trap successfully facilitated the removal of the dislodged catheter.

关键词： Implanted intravenous infusion port Fractured catheter Gooseneck trap Pigtail catheter Pulmonary Case report

Three-in-one incidence of hepatocellular carcinoma,cholangiocellular carcinoma,and neuroendocrine carcinoma:A case report

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World Journal of Clinical Cases 2022年第29期10卷 10575-10582页

作者： Yang Wu Chao-Bang Xie Yi-Huai He Di Ke Qiong Huang kai-fei zhao Rong-Shu Shi Department of Intervention The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Infection The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Pathology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Primary hepatic neuroendocrine carcinoma(NEC)is rare,and a combination with hepatocellular carcinoma(HCC)and cholangiocarcinoma(CCA)is extremely *** date,only four combination cases have been *** present paper describes the fifth *** SUMMARY A 32-year-old Chinese man with chronic hepatitis B was hospitalized for persistent upper abdominal *** computed tomography(CT)examination revealed a liver *** tumor was located in the 7th and 8th segments of the liver,and CT and magnetic resonance imaging findings were consistent with the diagnosis of *** examinations revealed the following:Alanine aminotransferase,243 U/L;aspartate aminotransferase,167 U/L;alpha-fetoprotein,4519μg/*** right lobe hepatectomy was performed on the liver *** pathology showed low differentiation HCC plus medium and low differentiation CCA combined with *** month after the surgery,the patient suffered from epigastric pain *** metastasis was detected by CT,and tumor transcatheter arterial chemoembolization was ***,the liver tumor was progressively increased and enlarged,and after 1 mo,the patient died of liver *** This is a rare case,wherein the tumor is highly aggressive,grows rapidly,and metastasizes in a short *** and laboratory tests can easily misdiagnose or miss such cases;thus,the final diagnosis relies on pathology.

关键词： Neuroendocrine carcinoma Hepatocellular carcinoma Mixed neuroendocrine neoplasm Combined hepatocellular-cholangiocarcinoma Cholangiocarcinoma Cholangiocellular carcinoma Case report

Primary signet-ring cell carcinoma of the extrahepatic bile duct:A case report

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World Journal of Gastrointestinal Oncology 2022年第7期14卷 1356-1362页

作者： Chao-Bang Xie Yang Wu Feng Li kai-fei zhao Rong-Shu Shi Qiong Huang Jin Ao Di Ke Department of Radiology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina Department of Pathology The Affiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina

BACKGROUND Signet ring cell carcinoma(SRCC)is a specific type of mucinous secretory adenocarcinoma,which contains abundant mucus in the cytoplasm and pushes the nucleus to one side of the cell membrane,forming a round or oval,and the nuclear deviations give the cells a signet ring-like *** often originates in the gastrointestinal tract,especially in the ***,primary SRCC of the extrahepatic bile duct is extremely ***,little is known about its epidemiology,treatment,and *** SUMMARY An 82-year-old female was admitted with abdominal pain,jaundice,and skin pruritus for 2 *** had no specific family *** examination presented normal vital signs,icteric sclera,visible jaundice,and mild tenderness in the right upper abdominal ***-related cell markers were within normal ***-enhanced computed tomography revealed a thickened wall of the common bile duct,strengthened with intrahepatic bile duct dilation and multiple round-like lesions in the *** addition,the lymph nodes in the hepatic hilum area,the pancreatic head area,and around the abdominal aorta were ***,a preoperative diagnosis of cholangiocarcinoma was *** alleviate jaundice and prolong the overall survival,percutaneous transhepatic cholangiopancreatic drainage(PTCD)was *** the operation,segmental stenosis of the extrahepatic bile duct and a vine-like expansion of the intrahepatic bile duct was ***,a biliary biopsy was performed under fluoroscopy to determine the nature and origin of the *** pathological diagnosis of the biopsy was ***,a diagnosis of primary SRCC of extrahepatic bile duct with distant lymph node metastasis and multiple liver metastases was made based on the radiographic,PTCD,and pathological *** tumor was diagnosed as T3N1M1 stage *** our aggressive approach,the patient died of liver failure after 1 *** This is the only

关键词： Cholangiocarcinoma Adenocarcinoma Signet ring cell carcinoma Extrahepatic bile duct Case report

Repetitive traumatic brain injury–induced complement C1–related inflammation impairs long-term hippocampal neurogenesis

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Neural Regeneration Research 2025年第3期20卷 821-835页

作者： Jing Wang Bing Zhang Lanfang Li Xiaomei Tang Jinyu Zeng Yige Song Chao Xu kai zhao Guoqiang Liu Youming Lu Xinyan Li kai Shu Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Neurosurgery Shanxi Bethune HospitalShanxi Academy of Medical SciencesTongji Shanxi HospitalThird Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Department of Pathophysiology School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Institute for Brain Research Wuhan Center of Brain ScienceHuazhong University of Science and TechnologyWuhanHubei ProvinceChina Department of Graduate Student Chongqing Medical UniversityChongqingChina Department of Basic Medicine School of Medical ScienceHubei University for NationalitiesEnshiHubei ProvinceChina Department of Anatomy School of Basic Medicine and Tongji Medical CollegeHuazhong University of Science and TechnologyWuhanHubei ProvinceChina

Repetitive traumatic brain injury impacts adult neurogenesis in the hippocampal dentate gyrus,leading to long-term cognitive ***,the mechanism underlying this neurogenesis impairment remains *** this study,we established a male mouse model of repetitive traumatic brain injury and performed long-term evaluation of neurogenesis of the hippocampal dentate gyrus after repetitive traumatic brain *** results showed that repetitive traumatic brain injury inhibited neural stem cell proliferation and development,delayed neuronal maturation,and reduced the complexity of neuronal dendrites and *** with repetitive traumatic brain injuryalso showed deficits in spatial memory ***,following repetitive traumatic brain injury,neuroinflammation was enhanced in the neurogenesis microenvironment where C1q levels were increased,C1q binding protein levels were decreased,and canonical Wnt/β-catenin signaling was *** inhibitor of C1 reversed the long-term impairment of neurogenesis induced by repetitive traumatic brain injury and improved neurological *** findings suggest that repetitive traumatic brain injury–induced C1-related inflammation impairs long-term neurogenesis in the dentate gyrus and contributes to spatial memory retrieval dysfunction.

关键词： complement C1 dendrite dentate gyrus hippocampus neural stem cell neurogenesis neuroinflammation neurological function neuron traumatic brain injury

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蜜胺纤维混纺纱工艺实践

棉纺织技术 2017年第6期45卷 59-61页

作者：孙凯飞赵雷张生辉陕西省纺织科学研究所陕西西安710038

探讨间位芳纶/蜜胺纤维/有机导电纤维50/48/2 18.5tex双股纱的生产工艺措施。通过原料预处理初步改善纤维混和均匀度和可纺性;在保证棉卷含水率的前提下,优选梳理针布、优化梳棉工艺参数;保证并条通道光洁,调整好粗纱的握持力;通过细纱... 详细信息

探讨间位芳纶/蜜胺纤维/有机导电纤维50/48/2 18.5tex双股纱的生产工艺措施。通过原料预处理初步改善纤维混和均匀度和可纺性;在保证棉卷含水率的前提下,优选梳理针布、优化梳棉工艺参数;保证并条通道光洁,调整好粗纱的握持力;通过细纱捻度的优化试验、钢领钢丝圈的选配和合理的热定形工艺,成功纺制出间位芳纶/蜜胺纤维/有机导电纤维50/48/2 18.5tex双股纱。认为:蜜胺纤维混纺纱可以满足阻燃防护服纱线使用要求。

关键词：蜜胺纤维间位芳纶梳理针布捻系数热定形

Precise gradient separation of nanoparticles using reduced graphene oxide-polyoxomolybdate membranes

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Science China Chemistry 2025年第01期 209-216页

作者： Yixin Yang Wanlei zhao Ruoxuan Zheng Hongqiang Li Wei Chen Yu-fei Song State Key Laboratory of Chemical Resource Engineering Beijing University of Chemical Technology Quzhou Institute for Innovation in Resource Chemical Engineering

The purification and size sieving of nanoparticles （NPs） represents a significant scientific ***,the r GO-polyoxometalates (POMs=PMo12,Mo132and Mo368) membranes were fabricated successfully via a simple and scalable POMsassisted in-situ photoreduction *** the mass ratio of r GO to PMo12was 1:30,the resultant r GO-PMo12membranes with highly ordered and uniform nanochannels of 1.0 nm can be obtained,which showed an accurate carbon quantum dots（CQDs） separation with a cut-off size approximately 1.0 *** increase of the size of the interlayered POMs from PMo12（1.0 nm）,{Mo132}（2.9 nm） to{Mo368}（3.8 nm）,the resultant r GO-PMo12,r GO-Mo132and r GO-Mo368exhibited precise gradient separation of CQDs and Au nanoparticles by size exclusion *** results pave a promising way to construct new twodimensional （2D） membranes for highly efficient size-selective separation.

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High-resolution imaging through dynamic scattering media: Iterative optimization based on polarimetric characteristics

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Science China Technological Sciences 2025年第1期 82-84页

作者： Meng XIANG kai DENG Tianyu WANG Jinpeng LIU Xue DONG Teli XI fei LIU Xiaopeng SHAO School of Optoelectronic Engineering Xidian University Xi'an Key Laboratory of Computational Imaging National Key Laboratory of Infrared Detection Technologies

High-resolution imaging through randomly dynamic scattered fields and highly scattered walls is an extensively sought-after capability with potential applications in various fields such as underwater imaging, biomedical imaging, and seeing through fog. Numerous methods have been proposed to unscramble object information from degraded scattered images, resulting in considerable improvements in image contrast in degraded scenarios [1].

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Activation of adult endogenous neurogenesis by a hyaluronic acid collagen gel containing basic fibroblast growth factor promotes remodeling and functional recovery of the injured cerebral cortex

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Neural Regeneration Research 2025年第10期20卷 2923-2937页

作者： Yan Li Peng Hao Hongmei Duan fei Hao Wen zhao Yudan Gao zhaoyang Yang Kwok-Fai So Xiaoguang Li Department of Neurobiology School of Basic Medical SciencesCapital Medical UniversityBeijingChina China Rehabilitation Science Institute China Rehabilitation Research CenterBeijing Key Laboratory of Neural Injury and RehabilitationBeijingChina Center of Neural Injury and Repair Beijing Institute for Brain DisordersBeijingChina Beijing Key Laboratory for Biomaterials and Neural Regeneration School of Engineering MedicineBeihang UniversityBeijingChina Guangdong-HongKong-Macao Institute of CNS Regeneration Ministry of Education CNS Regeneration Collaborative Joint LaboratoryJinan UniversityGuangzhouGuangdong ProvinceChina Bioland Laboratory(Guangzhou Regenerative Medicine and Health Guangdong Laboratory) GuangzhouGuangdong ProvinceChina Department of Ophthalmology and State Key Laboratory of Brain and Cognitive Sciences The University of Hong KongHong Kong Special Administration RegionChina Center for Brain Science and Brain-Inspired Intelligence Guangdong-HongKong-Macao Greater Bay AreaGuangzhouGuangdong ProvinceChina Co-innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Biomedical Engineering School of Biological Science and Medical EngineeringBeihang UniversityBeijingChina

The presence of endogenous neural stem/progenitor cells in the adult mammalian brain suggests that the central nervous system can be repaired and regenerated after ***,whether it is possible to stimulate neurogenesis and reconstruct cortical layers II to VI in non-neurogenic regions,such as the cortex,remains *** this study,we implanted a hyaluronic acid collagen gel loaded with basic fibroblast growth factor into the motor cortex immediately following traumatic *** findings reveal that this gel effectively stimulated the proliferation and migration of endogenous neural stem/progenitor cells,as well as their differentiation into mature and functionally integrated ***,these new neurons reconstructed the architecture of cortical layers II to VI,integrated into the existing neural circuitry,and ultimately led to improved brain *** findings offer novel insight into potential clinical treatments for traumatic cerebral cortex injuries.

关键词： adult endogenous neurogenesis basic fibroblast growth factor-hyaluronic acid collagen gel cortical remodeling functional recovery migration motor cortex injury neural circuits neural stem cells newborn neurons proliferation

Altering the Hierarchical Morphology Distribution of Injection Molded Polyethylene by the Introduction of Crosslink Network and Periodical Shear

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Chinese Journal of Polymer Science 2016年第12期34卷 1479-1489页

作者： Zhi-hao zhao fei-fei Wang Man Zhou kai-zhi Shen 张杰 College of Polymer Science and Engineer'ing State Key Laboratory of Polymer Materials En~neeringSichuan UniversityChengdu 610065China

High density polyethylene （HDPE） with moderate content of crosslink network （CPE） was successfully prepared through chemical method. Specimens for structural characterization have been molded by conventional injection molding （CIM） and pressure vibration injection molding （PVIM）. Influence of crosslink network on hierarchical morphology distribution and mechanical properties was systematically studied. Polarized light microscopy （PLM） revealed that both CIM and PVIM PE samples have a typical ＂skin-core＂ structure and the thickness of shear layer of CIM PE and PVIM CPE samples obviously increase. Scanning electron microscopy （SEM） showed that shish-kebab structures are clearly observed in shear layer of CIM CPE sample, indicating that the crosslink network can surely improve the formation of shish-kebab structures. Moreover, we suppose that shish-kebab structures emerged in shear and core layer of PVIM CPE sample. Wide- angle X-ray diffraction （WAXD） and small-angle X-ray scattering （SAXS） confirmed that more orientation and shish-kebab structures form even in core layer of PVIM CPE sample, which demonstrated that the hierarchical morphology was apparently altered by periodical shear and crosslink network. Finally, the mechanical properties revealed that this oriented structure increase the tensile strength from 31 MPa of CIM PE sample to 46 MPa of PVIM CPE sample. However, the tensile behavior tended to change from ductile fracture to brittle fracture.

关键词： Shish-kebab Morphology distribution Periodical shear Mechanical properties.

Growth traits and nitrogen assimilation-associated physiological parameters of wheat(Triticum aestivum L.) under low and high N conditions

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Journal of Integrative Agriculture 2015年第7期14卷 1295-1308页

作者： ZHANG fei-fei GAO Si zhao Yuan-yuan zhao Xiao-lei LIU Xiao-man XIAO kai College of Agronomy Agricultural University of Hebei

In this study, 14 wheat cultivars with contrasting yield and N use efficiency （NUE） were used to investigate the agronomic and NUE-related traits, and the N assimilation-associated enzyme activities under low and high N conditions. Under deficient-N, the cultivars with high N uptake efficiency （UpE） and high N utilization efficiency （UtE） exhibited higher plant biomass, yields, and N contents than those with medium and low NUEs. The high UpE cultivars accumulated more N than other NUE type cultivars. Under sufficient-N, the tested cultivars showed similar patterns in biomass, yield, and N content to those under deficient-N, but the varietal variations in above traits were smaller. In addition, the high UpE cultivars displayed much more of root biomass and larger of root length, surface area, and volume than other NUE type cultivars, indicating that the root morphological traits under N deprivation are closely associated with the plant biomass through its improvement of the N acquisition. The high UtE cultivars showed higher activities of nitrate reductase （NR）, nitrite reductase （NIR）, and gluta- mine synthetase （GS） at stages of seediling, heading and filling than other NUE type cultivars under both low and high N conditions. Moreover, the high UpE and UtE cultivars also displayed higher photosynthetic rate under deficient-N than the medium and low NUE cultivars. Together, our results indicated that the tested wheat cultivars possess dramatically genetic variations in biomass, yield, and NUE. The root morphological traits and the N assimilation enzymatic acitivities play critical roles in regulating N accumulation and internal N translocation under the N-starvation stress, respectively. They can be used as morphological and biochemical references for evaluation of UpE and UtE in wheat.

关键词： wheat (Triticum aestivum L.) low and high N biomass yield nitrogen use efficiency root morphological traits,N assimilzation-associated enzyme photosynthetic rate