检索结果-南通市图书馆

Panda X-III： Searching for neutrinoless double beta decay with high pressure ^(136)Xe gas time projection chambers

Science China(Physics,Mechanics & Astronomy) 2017年第6期60卷 8-47页

作者： Xun Chen Chang Bo Fu Javier Galan Karl Giboni Franco Giuliani Ling Hui Gu Ke Han xiang Dong Ji Heng Lin Jiang Lai Liu kai xiang ni Hiroki Kusano xiang xiang Ren Shao Bo Wang Yong Yang Dan Zhang Tao Zhang Li Zhao xiang Ming Sun Shou Yang Hu Si Yu Jian Xing Long Li Xiao Mei Li Hao Liang Huan Qiao Zhang Ming Rui Zhao Jing Zhou Ya Jun Mao Hao Qiao Si Guang Wang Ying Yuan Meng Wang Amir N.Khan Neill Raper Jian Tang Wei Wang Jia ning Dong Chang Qing Feng Cheng Li Jian Bei Liu Shu Bin Liu Xiao Lian Wang Dan Yang Zhu Juan F.Castel Susana Cebri'an Theopisti Dafni Javier G.Garza Igor G.Irastorza Francisco J.Iguaz Gloria Luz ′on Hector Mirallas Stephan Aune Eric Berthoumieux Yann Bedfer Denis Calvet nicole d'Hose Alain Delbart Maria Diakaki Esther Ferrer-Ribas Andrea Ferrero Fabienne Kunne Damien Neyret Thomas Papaevangelou Franck Sabatie Maxence Vanderbroucke AnDi Tan Wick Haxton Yuan Mei Chinorat Kobdaj Yu-Peng Yan NPAC and Department of Physics and Astronomy Shanghai Jiao Tong University Shanghai Laboratory for Particle Physics and Cosmology Shanghai 200240 China College of Physical Science and Technology Central China Normal University Wuhan 430079 China China Institute of Atomic Energy Beijing 102413 China School of Physics Peking University Beijing 100871 China School of Physics and Key Laboratory of Particle Physics and Particle Irradiation (MOE) Shandong University Jinan 250100 China School of Physics and Engineering Sun Yat-Sen University Guangzhou 510275 China Department of Modern Physics University of Science and Technology of China Hefei 230026 China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of China Hefei 230026 China University ofZaragoza C/P Cerbuna 12 50009 Zaragoza Spain IRFU CEA Universite Paris-Saclay F-91191 Gif-sur-Yvette France Department of Physics University of Maryland College Park MD 20742 USA Nuclear Science Division Lawrence Berkeley National Laboratory Berkeley CA 94720 USA Center for Excellence in High Energy Physics and Astrophysics Suranaree University of Technology Nakhon Ratchasima 30000 Thailand

Searching for the neutrinoless double beta decay(NLDBD)is now regarded as the topmost promising technique to explore the nature of neutrinos after the discovery of neutrino masses in oscillation *** X-III(particle and astrophysical xenon experiment III)will search for the NLDBD of136Xe at the China Jin Ping Underground Laboratory(CJPL).In the first phase of the experiment,a high pressure gas Time Projection Chamber(TPC)will contain 200 kg,90%136Xe enriched gas operated at10 *** pitch micro-pattern gas detector(Microbulk Micromegas)will be used at both ends of the TPC for the charge readout with a cathode in the *** signals can be used to reconstruct the electron tracks of the NLDBD events and provide good energy and spatial *** detector will be immersed in a large water tank to ensure～5 m of water shielding in all *** second phase,a ton-scale experiment,will consist of five TPCs in the same water tank,with improved energy resolution and better control over backgrounds.

关键词： neutrinoless double beta decay lepton number violation underground experiment TPC Micromegas

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

PCK1 dysregulation in cancer: Metabolic reprogramming, oncogenic activation, and therapeutic opportunities

引用

Genes & Diseases 2023年第1期10卷 101-112页

作者： Jin xiang kai Wang ni Tang Key Laboratory of Molecular Biology for Infectious Diseases(Ministry of Education) Institute for Viral HepatitisDepartment of Infectious DiseasesThe Second Affiliated Hospital of Chongqing Medical UniversityChongqing 400010China

The last few decades have witnessed an advancement in our understanding of multiple cancer cell pathways related to metabolic *** of the most important cancer hallmarks,including aerobic glycolysis(the Warburg effect),the central carbon pathway,and multiple-branch metabolic pathway remodeling,enables tumor growth,progression,and *** carboxykinase1(PCK1),a key rate-limiting enzyme in gluconeogenesis,catalyzes the conversion of oxaloacetate to ***1 expression in gluconeogenic tissues is tightly regulated during *** tumor cells,PCK1 is regulated in a cell-autonomous manner rather than by hormones or nutrients in the extracellular ***,PCK1has ananti-oncogenic role in gluconeogenic organs(the liver and kidneys),but a tumor-promoting role in cancers arising from non-gluconeogenic *** studies have revealed that PCK1 has metabolic and non-metabolic roles in multiple signaling networks linking metabolic and oncogenic *** PCK1 expression results in the activation of oncogenic pathways,accompanied by metabolic reprogramming,to maintain *** this review,we summarize the mechanisms underlying PCK1 expression and regulation,and clarify the crosstalk between aberrant PCK1 expression,metabolic rewiring,and signaling pathway *** addition,we highlight the clinical relevance of PCK1 and its value as a putative cancer therapeutic target.

关键词： Gluconeogenesis Metabolism Oncogenesis PCK1 Tumor

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

川西亚高山森林林窗对凋落枝早期分解的影响

引用

植物生态学报 2018年第1期42卷 28-37页

作者：郭彩虹杨万勤吴福忠徐振锋岳楷倪祥银袁吉杨帆谭波四川农业大学生态林业研究所长江上游林业生态工程四川省重点实验室高山森林生态系统定位研究站水土保持与荒漠化防治省级重点实验室成都611130 长江上游生态安全协同创新中心成都611130

林窗调控的土壤水热环境和分解者群落结构可能深刻影响凋落物分解过程,已有的研究结果具有不确定性。为了解高海拔森林林窗面积对凋落枝分解的影响,采用凋落物分解袋法,于2012–2016年冬季和生长季节,研究了川西亚高山森林255–290 m^2(... 详细信息

林窗调控的土壤水热环境和分解者群落结构可能深刻影响凋落物分解过程,已有的研究结果具有不确定性。为了解高海拔森林林窗面积对凋落枝分解的影响,采用凋落物分解袋法,于2012–2016年冬季和生长季节,研究了川西亚高山森林255–290 m^2(FG1)、153–176 m^2(FG2)、38–46 m^2(FG3)3种面积林窗和林下对岷江冷杉(Abies faxoniana)凋落枝质量损失的影响。结果显示:林窗面积大小显著改变了林窗和林下的雪被厚度、温度和冻融循环频次;雪被厚度和温度以FG1林窗最高,林下最低;FG1、FG2、FG3林窗和林下枝条分解4年后的质量残留率分别为59.9%、59.5%、62.1%和55.3%,分解系数k值分别为0.127、0.131、0.120和0.135,95%分解时间分别为23.6、22.7、25.0和22.2 a;与林下相比,林窗显著增加了第一年和第二年生长季节的质量损失速率,降低了第一年和第四年冬季的枝条质量损失速率;林窗大小对质量损失速率的影响随分解时期变化差异明显,质量损失速率在第一年和第三年冬季随林窗面积增大而增大,在第三年生长季节随林窗面积增大而降低;枝条质量损失的比例在第一年最高,随林窗面积增加而增加,且冬季高于生长季节。综上所述,林窗环境变化深刻影响亚高山森林凋落枝分解,但这种影响随林窗面积和分解时间有所差异。

关键词：林窗凋落枝质量损失亚高山森林

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The Full Load Voltage Compensation Strategy in Capacity Configuration of UPQC Integrated PV-BESS

引用

Energy Engineering 2023年第5期120卷 1203-1221页

作者： Fuyin ni kai Li Jiangsu Key Laboratory of Power Transmission&Distribution Equipment Technology JiangsuUniversity of TechnologyChangzhou213001China School of Electrical and Information Engineering Jiangsu University of TechnologyChangzhou213001China

Unified power quality conditioner(UPQC)with energy storage is commonly based on conventional capacity configuration strategy with power angle *** has problems such as phase jumping before and after ***-link cannot continuously emit active power ***,this paper presents the compensation strategy of full load voltage magnitude and phase in capacity configuration of *** topology of UPQC is integrated a series active power filter(SAPF),a shunt active power filter(PAPF)and a photovoltaic-battery energy storage system(PV-BESS).The principle of full load voltage compensation is analyzed based on the PV-BESS-UPQC *** constant of load voltage ismaintained by controlling the appropriate shunt compensation *** the UPQC capacity configuration is carried out using the full load voltage compensation *** compensation capacity of UPQC series and shunt units are ***,the simulation results show that the proposed compensation strategy reduces the capacity configuration by 5.11 kVA(36.4%)compared to the conventional compensation *** proposed strategy can achieve full compensation of the load voltage,which can effectively reduce the capacity allocation and improve the economy of *** also has the PV-BESS units’ability of providing active power and can stabilize the DC-link voltage.

关键词： Unified power quality conditioner solar photovoltaic battery energy storage system full compensation capacity configuration strategy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Assessment of water-based cutting fluids with green additives in broaching

引用

Friction 2020年第6期8卷 1051-1062页

作者： Jing ni kai FENG Lihua HE Xiaofan LIU Zhen MENG School of Mechanical Engineering Hangzhou Dianzi UniversityHangzhou 310018China

In order to improve the cutting performance in broaching,the lubrication and cleaning effects offered by water-based cutting fluids with green additives need to be studied from the viewpoint of green ***,water-based solutions with castor oil,surfactant(linear alkylbenzene sulfonate,LAS),and nanographite were prepared by ultrasonic agitation and sprayed into the zone of broaching via *** performances of the cutting fluids,in terms of the viscosity,specific heat,wetting angle,and droplet size,were evaluated to discuss their effects on the broaching *** the fluids,the addition of LAS into oil-in-water(WO-S),where its cutting fluid with 10 wt.%castor oil and 1.5 wt.%surfactant,exhibited the lowest broaching *** regard to the lubricating and cleaning mechanisms,WO-S has good wettability and permeability,and hence,can lubricate the cutting edge of the tool to decrease the cutting load,cool the cutting edge to keep it sturdy,and clean the surface of the cutting edge to keep it *** results reveal that the simultaneous addition of castor oil and LAS had remarkable effects on the lubrication and cleaning,and resulted in a broaching load reduction of more than 10%compared to commercial cutting ***,the addition of nanographite could not improve the lubrication owing to its agglomeration.

关键词： cutting fluid castor oil linear alkylbenzene sulfonate nanographite broaching

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The growth mechanisms of θ’ precipitate phase in an Al-Cu alloy during aging treatment

引用

Journal of Materials Science & Technology 2021年第2期61卷 25-32页

作者： Lin Gao kai Li Song ni Yong Du Min Song State Key Laboratory of Powder Metallurgy Central South UniversityChangsha 410083China

The plate-shaped θ’(Al2 Cu) precipitate acts as one of the primary strengthening phases in Al-Cu *** interface,especially the semicoherent interface,between Al-Cu solid solution(αAl) and θ’ phase contains a lot of clues about phase ***,these interfacial structures in an Al-Cu alloy after high-temperature and longtime aging have been analyzed in detail using atomic-scale high-angle annular dark-field scanning transmission electron microscopy and first-principles calculations in this *** was found that the lateral growth of θ’ precipitates is subjected to a combination of several major mechanisms under this aging *** for some common intermediate phases,two novel and striking structures were observed on the interface,which implies two alternative atomic diffusion mechanisms for θ’ precipitate *** one condition,the atomic diffusion from αAl to θ’ phase transformation adopts an interstitialcy mechanism based on additional Al *** the other condition,the diffusion is carried out through Al *** mechanisms are distinctly different from the previous theory based on direct diffusion of Cu *** first-principle calculations also confirm that these newfound diffusion processes are ene rgetically favored.

关键词： Al-Cu alloys Phase transformation Atomic-scaled imaging First-principles calculation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Functions and mechanisms of cytosolic phospholipase A_(2)in central nervous system trauma

引用

Neural Regeneration Research 2023年第2期18卷 258-266页

作者： Hao-Jie Zhang Yi-Tuo Chen Xin-Li Hu Wan-Ta Cai xiang-Yang Wang Wen-Fei ni kai-Liang Zhou Department of Orthopedics The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical UniversityWenzhouZhejiang ProvinceChina Zhejiang Provincial Key Laboratory of Orthopedics WenzhouZhejiang ProvinceChina The Second Clinical Medical College of Wenzhou Medical University WenzhouZhejiang ProvinceChina

Central nervous system(CNS)trauma,including traumatic brain injury and spinal cord injury,has a high rate of disability and mortality,and effective treatment is currently *** studies have revealed that neural inflammation plays a vital role in CNS *** the initial enzyme in neuroinflammation,cytosolic phospholipase A_(2)(cPLA2)can hydrolyze membranous phosphatides at the sn-2 position in a preferential way to release lysophospholipids andω3-polyunsaturated fatty acid dominated by arachidonic acid,thereby inducing secondary *** there is substantial fresh knowledge pertaining to cPLA2,in-depth comprehension of how cPLA2 participates in CNS trauma and the potential methods to amelio rate the clinical res ults after CNS trauma are still *** present review summarizes the latest understanding of how cPLA2 participates in CNS trauma,highlighting novel findings pertaining to how cPLA2 activation initiates the potential mechanisms specifically,neuroinflammation,lysosome membrane functions,and autophagy activity,that damage the CNS after ***,we focused on testing a variety of drugs capable of inhibiting cPLA2 or the upstream pathway,and we explored how those agents might be utilized as treatments to improve the results following CNS *** review aimed to effectively understand the mechanism of cPLA2 activation and its role in the pathophysiological processes of CNS trauma and provide clarification and a new referential framework for future research.

关键词： autophagy cytosolic phospholipase A_(2) drugs lysosome membrane permeability mitogen-activated protein kinase neuroinflammation spinal cord injury traumatic brain injury

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A comparative study of two single-stage oral mucosal substitution urethroplasty(Kulkarni and Asopa)in the surgical treatments of lichen sclerosus urethral strictures

引用

Asian Journal of Andrology 2023年第6期25卷 719-724页

作者： xiang Wan Hai-Jun Yao Min-kai Xie Jian-Shu ni Da-Jun Gao Zhong Wang Bin Xu Da-Chao Zheng Department of Urology Shanghai Ninth People’s HospitalShanghai Jiao Tong University School of MedicineShanghai 200011China

Long-segment lichen sclerosus(LS)urethral stricture is a challenge for *** data are available for surgeons to make a surgical decision between Kulkarni and Asopa *** this retrospective study,we investigated the outcomes of these two procedures in patients with LS urethral *** January 2015 and December 2020,77 patients with LS urethral stricture underwent Kulkarni and Asopa procedures for urethroplasty in the Department of Urology,Shanghai ninth People’s Hospital,Shanghai Jiao Tong University School of Medicine(Shanghai,China).Of the 77 patients,42(54.5%)underwent the Asopa procedure and 35(45.5%)underwent the Kulkarni *** overall complication rate was 34.2%in the Kulkarni group and 19.0%in the Asopa group,and no difference was observed(P=0.105).Among the complications,no statistical difference was observed in the incidence of urethral stricture recurrence(P=0.724)or glans dehiscence(P=0.246)except for postoperative meatus stenosis(P=0.020).However,the recurrence-free survival rate between the two procedures was significantly different(P=0.016).Cox survival analysis showed that antiplatelet/anticoagulant therapy use(P=0.020),diabetes(P=0.003),current/former smoking(P=0.019),coronary heart disease(Pniques can still provide acceptable results with their own advantages in the surgical treatment of LS urethral *** surgical alternative should be considered comprehensively according to the patient characteristics and surgeon ***,our results showed that antiplatelet/anticoagulant therapy use,diabetes,coronary heart disease,current/former smoking,and stricture length may be contributing factors of ***,patients with LS are advised to undergo early interventions for better therapeutic effects.

关键词： lichen sclerosus oral mucosal graft urethral stricture urethroplasty

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Construction of hollow polydopamine nanoparticle based drug sustainable release system and its application in bone regeneration

引用

International Journal of Oral Science 2021年第3期13卷 282-291页

作者： Lu Wang Shuwei Liu Chunxia Ren Siyuan xiang Daowei Li Xinqing Hao Shilei ni Yixin Chen kai Zhang Hongchen Sun Department of Oral Pathology Hospital of StomatologyJilin UniversityChangchunChina Jilin Provincial Key Laboratory of Tooth Development and Bone Remodeling School and Hospital of StomatologyJilin UniversityChangchunChina State Key Laboratory of Supramolecular Structure and Materials College of ChemistryJilin UniversityChangchunChina

Nanomaterial-based drug sustainable release systems have been tentatively applied to bone ***,however,still face disadvantages of high toxicity,low biocompatibility,and low drug-load *** view of the low toxicity and high biocompatibility of polymer nanomaterials and the excellent load capacity of hollow nanomaterials with high specific surface area,we evaluated the hollow polydopamine nanoparticles(HPDA NPs),in order to find an optimal system to effectively deliver the osteogenic drugs to improve treatment of bone *** demonstrated that the HPDA NPs synthesized herein could efficiently load four types of osteogenic drugs and the drugs can effectively release from the HPDA NPs for a relatively longer time in vitro and in vivo with low toxicity and high *** of qRT-PCR,ALP,and alizarin red S staining showed that drugs released from the HPDA NPs could promote osteogenic differentiation and proliferation of rat bone marrow mesenchymal stem cells(rBMSCs)in *** data from micro-CT and H&E staining showed that all four osteogenic drugs released from the HPDA NPs effectively promoted bone regeneration in the defect of tooth extraction fossa in vivo,especially *** results suggest that the HPDA NPs,the biodegradable hollow polymer nanoparticles with high drug load rate and sustainable release ability,have good prospect to treat the bone defect in future clinical practice.

关键词： drugs dopamine release

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Clinical andTransmission Characteristics of COVID-19-A Retrospective Study of 25 Cases from a Single Thoracic Surgery Department

引用

Current Medical Science 2020年第2期40卷 295-300页

作者： Yang-kai LI Shu PENG Le-qun LI Qi WANG Wei PING ni ZHANG xiang-ning FU Deparnent of Thoracic Surgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWiuhan 430030China

The outbreak of corona virus disease 2019(COVID-19)imposes a major challenge in managing patients undergoing surgical *** this study,we analyzed clinical and transmission features of 25 cases of COVID-19 from a single thoracic department,including 13 patients and 12 health care *** were 13 males and 12 *** median age of the patients was 61(range:51 to 69)*** median age of the health care staff was 35(range:22 to 51)*** the end of follow-up date(Mar.3,2020),there were 16 non-severe cases(64%)and 9 severe cases(36%),5 cases were dead(20%).nineteen(76%)of the infected cases were confirmed by SARS-CoV-2 nucleic acid test,the rest were clinically diagnosed as suspected COVID-19 cases,and 19(76%)of the infected cases had positive exposure *** found that COPD was significantly associated with severity and death(P-0.040,and P=0.038,respectively),and chest operation was significantly associated with death for COVID-19 patients(P-0.039).A potential“super spreader"may be the source of the transmission before the implementation of quarantine and comprehensive *** was concluded that COVID-19 is associated with poor prognosis for patients undergoing thoracic operation,especially for those with *** of comprehensive protective measures is important to control nosocomial infection.

关键词： corona virus disease 2019 SARS-CoV-2 nosocomial infection

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：