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Detection of Regional Wall Motion Abnormalities in Compressed Sensing Cardiac Cine Imaging

World Journal of Cardiovascular Diseases 2018年第6期8卷 277-287页

作者： Juliane Goebel Felix Nensa Haemi Schemuth Stefan Maderwald Harald H. Quick Thomas Schlosser kai nassenstein Department of Diagnostic and Interventional Radiology and Neuroradiology University Hospital Essen Essen Germany Erwin L. Hahn Institute for Magnetic Resonance Imaging University of Duisburg-Essen Essen Germany High Field and Hybrid MR Imaging University of Duisburg-Essen Essen Germany

Background: Recently faster cardiac magnetic resonance (CMR) cine sequences basing on k-t compressed sensing have been developed. Purpose: To compare two compressed sensing CMR sequences-one in breath-hold technique and one during free breathing—with the standard SSFP sequence with respect to regional left ventricular function assessment. Material and Methods: Left ventricular short-axis stacks of two compressed sensing sequences in breath-hold technique (sparse_HB) and during free breathing (sparse_FB;both spatial resolution, 1.8 × 1.8 × 8 mm3) and a standard SSFP cine sequence (spatial resolution, 1.9 × 1.9 × 8 mm3) were acquired in 50 patients on a 1.5 T MR system. Regional wall motion abnormalities (RWMA) were rated qualitatively (normal/hypo-/a-/dyskinesia) by two experienced readers in consensus for all cardiac segments (American Heart Association’s segment model) and sequences. RWMA detection rates were compared between sequences by kappa statistic. Results: In 13 patients, RWMA were detected in at least one cardiac segment. The RWMA detection rates were similar between CMR sequences (hypokinesia, 7.2% to 7.9%;akinesia, 0.8% to 1.3%;dyskinesia 0.3% to 0.4%) and kappa statistics revealed an almost perfect agreement in RWMA detection between both sparse and the standard SSFP sequence (standard versus sparse_HB: kappa, 0.918, p value, p value, Conclusion: Compressed sensing cine CMR acquired during breath-hold or free-breathing allows reliable RWMA detection, thus, might alternatively be used in cine CMR for regional left ventricular function assessment.

关键词： Cardiac Imaging Techniques Cine Magnetic Resonance Imaging Cardiac Muscle Cardiac Volume Myocardial Contraction

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Integrated Assessment of Cardiac PET/MRI: Co-Registered PET and MRI Polar Plots by Mutual MR-Based Segmentation of the Left Ventricular Myocardium

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World Journal of Cardiovascular Diseases 2017年第4期7卷 91-104页

作者： Felix Nensa Thorsten D. Poeppel Ercan Tezgah Philipp Heusch kai nassenstein Michael Forsting Andreas Bockisch Raimund Erbel Thomas Schlosser Department of Diagnostic and Interventional Radiology and Neuroradiology University Hospital Essen University of Duisburg-Essen Essen Germany Clinic for Nuclear Medicine University Hospital Essen University of Duisburg-Essen Essen Germany Clinic for Cardiology University Hospital Essen University of Duisburg-Essen Essen Germany Department of Diagnostic and Interventional Radiology University Hospital Dusseldorf University of Dusseldorf Dussel-dorf Germany

Background: In the present study, we sought to describe a procedure for the creation of co-registered positron emission tomography (PET) and magnetic resonance imaging (MRI) polar plots of cardiac PET/MRI examinations, validate the resulting plots against available standard methods in patients with myocardial infarction and provide examples that demonstrate the advantage of the novel approach over existing standards. Methods: Co-registered LGE and PET short-axis images were transformed into polar maps based on a radial sampling pattern. LGE was automatically detected using an automated thresholding algorithm (ATA). In 20 PET/MRI examinations in patients with acute myocardial infarction, agreement between manual LGE assessment and the ATA classification was calculated. Also agreement between MRI-segmentation based PET polar plots and standard PET polar plots (created with the Corridor4DM software package) was assessed. Results: No statistically significant difference in infarct sizes between manual and ATA segmentation was found (p = 0.12). Both methods were highly correlated (Pearson’s r = 0.96, p Conclusion: A straightforward software approach for the creation of co-registered PET and MRI polar plots was described and successfully demonstrated in PET/MRI studies of myocardial infarction and inflammation.

关键词： Cardiac PET/MRI Bull’s Eye Polar Plot Polar Map

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