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Non-alcoholic fatty liver disease: The diagnosis and management

World Journal of Hepatology 2015年第6期7卷 846-858页

作者： Shehab M Abd El-kader Eman M Salah El-Den Ashmawy Department of Physical Therapy Faculty of Applied Medical Sciences King Abdulaziz University Department of Physical Therapy for Cardiopulmonary Disorders and Geriatrics Faculty of Physical Therapy Cairo University

Non-alcoholic fatty liver disease(NAFLD) is now the most frequent chronic liver disease that occurs across all age groups and is recognized to occur in 14%-30% of the general population, representing a serious and growing clinical problem due to the growing prevalence of obesity and overweight. Histologically, it resembles alcoholic liver injury but occurs in patients who deny significant alcohol consumption. NAFLD encompasses a spectrum of conditions, ranging from benign hepatocellular steatosisto inflammatory nonalcoholic steatohepatitis, fibrosis, and cirrhosis. The majority of hepatocellular lipids are stored as triglycerides, but other lipid metabolites, such as free fatty acids, cholesterol, and phospholipids, may also be present and play a role in disease progression. NAFLD is associated with obesity and insulin resistance and is considered the hepatic manifestation of the metabolic syndrome, a combination of medical conditions including type 2 diabetes mellitus, hypertension, hyperlipidemia, and visceral adiposity. Confirmation of the diagnosis of NAFLD can usually be achieved by imaging studies; however, staging the disease requires a liver biopsy. Current treatment relies on weight loss and exercise, although various insulin-sensitizing agents, antioxidants and medications appear promising. The aim of this review is to highlight the current information regarding epidemiology, diagnosis, and management of NAFLD as well as new information about pathogenesis, diagnosis and management of this disease.

关键词： Non-alcoholic fatty liver disease Nonalcoholicsteatohepatitis Liver disease

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Franco-Malian and Sino-Malian Economic Cooperation:A Comparison

Franco-Malian and Sino-Malian Economic Cooperation:A Compari...

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作者：古开达（Abdoul kader COULIBALY）中南财经政法大学

学位级别：硕士

1960年以来,法国和中国一直是马里的两个非常重要国际合作伙伴。在法国和马里关系方面,法国是马里的前殖民宗主国。马里独立以来,法国与马里开展了双边合作,这属于南北合作,对两国的经济发展十分重要。虽然遇到了一些困难,但法国和马里... 详细信息

1960年以来,法国和中国一直是马里的两个非常重要国际合作伙伴。在法国和马里关系方面,法国是马里的前殖民宗主国。马里独立以来,法国与马里开展了双边合作,这属于南北合作,对两国的经济发展十分重要。虽然遇到了一些困难,但法国和马里的合作关系从未中断。法国与马里之间的经济关系,主要是法国在马里进行投资,法国在经济上支持马里并为马里提供官方发展援助。此外,自马里独立以来,法国和马里之间一直存在商品贸易。然而,法国与马里之间的经济关系也存在问题,主要表现为两国经济合作存在不对称性、法国移民政策收紧、腐败问题以及法国通过经济影响力在马里寻求地缘政治作用,等等。在中国和马里方面,马里独立后不久中马两国就建立了外交关系。中马合作最初是在南南合作框架下进行的,遵循万隆会议的不干涉内政和各国相互尊重等原则。1962年,中国和马里签署了经济合作协议。此后,通过相互投资、官方发展援助和贸易交流,两国经济合作日益密切。与马里与法国的经济合作不同的是,中马经济合作的重点领域是建设基础设施,中国向马里提供无息贷款和补助金。中国和马里经济合作也存在问题,主要包括中国企业不注意保护当地环境、不愿意雇佣当地工人以及马里存在恐怖主义安全威胁问题等。在马里与中国和法国建立了经济合作关系后,尽管遭遇了一些变化和困难,但这些经济合作都长期保持并促进了马里的经济发展。立足于法国马里经济合作以及中国马里经济合作情况、合作成就以及问题,本文比较了两种合作的异同。在相同点方面,中国和马里在目标是都是寻求在马里扩大经济利益,两国与马里都在投资、官方发展援助和贸易方面保持密切的合作与交流。由于马里存在管理不善、政府腐败、人才不足、恐怖主义安全威胁等问题,法国马里以及中国马里的经济合作存在一些困难。不同的是,法国在马里是致力于通过经济影响力来保持和扩大地缘政治影响力,而中国奉行不干涉内政的原则,中国与马里的合作重点是基础设施建设,更多地是开展政府间合作和寻求合作共赢。最后,从南南合作和南北合作的性质及新发展的宏观视角,本文指出中国马里合作的快捷发展显示立足与合作共赢和互不干涉内政的国际合作方式更有生命力,法国在马里的苛刻经济合作政策和干涉内政行动限制了南北合作的发展。但是,新时期南南合作也出现了新的问题,中国应该尊重当地社会和保护当地利益,真正实现合作共赢。马里从与法国及中国的合作中都获得了收益,未来需要采取措施规避两种合作的负面因素,并避免南南合作与南北合作之间的激烈竞争,促进两种合作在马里发挥更大的积极作用。

关键词：中国法国马里经济合作

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Comparison of the Effectiveness of TRV Chair and Canalith Repositioning Procedure (CRP) for the Treatment of Benign Paroxysmal Positional Vertigo (BPPV)

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International Journal of Otolaryngology and Head & Neck Surgery 2022年第4期11卷 143-153页

作者： Abdul kader Afif Yamout The School of Advanced Education Research and Accreditation (SAERA) Castelló Spain

The primary goal of this research is to evaluate the efficacy of traditional manual canalith repositioning procedures (CRP) to that of automated multi-axial repositioning chair (TRV). A total of 37 BPPV positive patients were distributed into two groups. The first group consisted of 20 patients, 10 under 50 years old (young group) and 10 over 50 years old (old group), who received TRV chair treatment, whereas the remaining 17 patients, 7 under 50 years old (young group) and 10 over 50 years old (old group) received CRP treatment. The DHI and VAS questionnaires were given to the patients before and after treatment, and the results were compared. The average VAS score for TRV patients was 84.5% (young group) and 77.5% (old group). These patients’ DHI results were as follows: for young patients, 10% had a mild handicap, 80% had a moderate handicap, and 10% had a severe handicap, while for the elderly, 40% had a mild handicap, 40% had a moderate handicap, and 20% had a severe handicap. The results improved significantly after the first treatment session. Old patients had a VAS of 28%, 30% had a mild handicap and only 10% had a moderate handicap. However, only 43% of the young group and 30% of the old group who underwent standard CRP suffered from mild handicap and had a VAS of 20% and 34.3% successively. The third session revealed that all patients in the TRV chair group had no handicap, whereas the CRP patients indicated that they still had a mild handicap. Upon analyzing the results, both treatment methods revealed the same efficacy in treating single canal BPPV. However, TRV chair appeared to be superior to traditional CRP in treating multi-canal BPPV.

关键词： Manual Repositioning Procedure Vertigo DHI CRP BPPV VAS TRV Chair

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西北干旱区机场低空风切变基本特征分析

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干旱气象 2024年第3期42卷 347-356页

作者：曼吾拉·卡德尔刘鑫华李云翔关文娟中国气象局航空气象重点开放实验室北京100081 新疆机场(集团)有限责任公司新疆乌鲁木齐830000 国家气象中心北京100081

为提升对西北干旱区低空风切变特征的认识,对该区域民航飞行安全提供可靠的气象服务保障,以新疆为例,利用机场语音方式航空器报告、机场例行观测实况报文、维萨拉(Vaisala)气象自动观测系统数据、飞机机载探测资料、欧洲中期天气预报中... 详细信息

为提升对西北干旱区低空风切变特征的认识,对该区域民航飞行安全提供可靠的气象服务保障,以新疆为例,利用机场语音方式航空器报告、机场例行观测实况报文、维萨拉(Vaisala)气象自动观测系统数据、飞机机载探测资料、欧洲中期天气预报中心(European Centre for Medium-Range Weather Forecasts,ECMWF)第五代大气再分析资料(ERA5)对新疆区域17个机场接收的低空风切变报告进行统计,并对喀什机场一次典型低空风切变事件进行分析。结果表明:新疆地区低空风切变四季均有出现,夏季出现频率最高,低空风切变在90~300 m高度范围内频发,主要集中发生在中午至傍晚时段,中等强度的低空风切变出现频次最多,小机型飞机更易遭遇低空风切变。低空风切变发生时机场常受500 hPa西风气流型、低涡型、低槽型天气系统影响,且多伴有低空急流、地面大风及对流云等情况,特殊的地形环境也是影响新疆部分机场低空风切变频发的原因之一。对喀什机场一次典型低空风切变个例分析后发现,在低槽型天气系统影响下,飞机进近和复飞过程中遭遇了强风切变,包括强水平风向、风速的切变和强垂直风切变,在中小尺度系统影响下飞机在下降过程中极有可能遭遇下击暴流,从而引发强低空风切变。

关键词：低空风切变低空急流自动观测资料机载观测资料新疆机场

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Conjugated hyperbilirubinemia presenting in first fourteen days in term neonates

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World Journal of Hepatology 2017年第26期9卷 1108-1114页

作者： Fang Kuan Chiou Christina Ong Kong Boo Phua Fares Chedid Ajmal kader Gastro-enterology Service Paediatric Medicine KK Women’s and Children’s Hospital Neonatal Medicine Al Jalila Children’s Specialty Hospital Pediatric Gastroenterology Dubai Hospital

AIM To describe the etiology and characteristics of earlyonset conjugated hyperbilirubinemia(ECHB) presenting within 14 d of life in term *** Retrospective review was performed of term infants up to 28-d-old who presented with conjugated hyperbilirubinemia(CHB) at a tertiary center over a 5-year period from January 2010 to December 2014. CHB is defined as conjugated bilirubin(CB) fraction greater than 15% of total bilirubin and CB greater or equal to 25 μmol/L. ECHB is defined as CHB detected within 14 d of life. "Late-onset" CHB(LCHB) is detected at 15-28 d of life and served as the comparison *** Total of 117 patients were recruited: 65 had ECHB, 52had LCHB. Neonates with ECHB were more likely to be clinically unwell(80.0% vs 42.3%, P < 0.001) and associated with non-hepatic causes(73.8% vs 44.2%, P = 0.001) compared to LCHB. Multifactorial liver injury(75.0%) and sepsis(17.3%) were the most common causes of ECHB in clinically unwell infants, majority(87.5%) had resolution of CHB with no progression to chronic liver disease. Inborn errors of metabolism were rare(5.8%) but associated with high mortality(100%) in our series. In the subgroup of clinically well infants(n = 13) with ECHB, biliary atresia(BA) was the most common diagnosis(61.5%), all presented initially with normal stools and decline in total bilirubin but with persistent CHB. CONCLUSION Secondary hepatic injury is the most common reason for ECHB. BA presents with ECHB in well infants without classical symptoms of pale stools and deep jaundice.

关键词： Conjugated hyperbilirubinemia Biliary atresia Cholestasis Direct hyperbilirubinemia Neonatal jaundice

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LSND法焊接镍合金薄板结构有限元分析(英文)

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天津大学学报 1993年第2期26卷 1-7页

作者：单平 Norrish J Al-kader M 天津大学英国Cranfield工学院

翘曲变形是薄板结构焊接时难以避免的问题,它严重影响产品的质量。近年来在试验研究的基础上发展了一种低应力无变形焊接工艺(LSND),本文根据有限元分析结果对这一工艺作进一步探讨。

关键词：薄板结构焊接镍合金 LSND法

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Explication of Emergency Dwellings in Turkey in the Context of Cultural Continuity:Fieldwork in Alagoz Village

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Open Journal of Earthquake Research 2012年第2期1卷 22-28页

作者： Ferah Akinci kader Dagistanli Faculty of Architecture Yildiz Technical UniversityIstanbulTurkey

The study is a fieldwork in Alag?z Village in Bing?l which is situated in the Eastern Anatolia Region of Turkey. Ma- jority of the traditional houses in Alag?z Village were destroyed by earthquakes. Standard type houses were built within the scope of “Earthquake houses” project by the state under the initiative for closing the gap of housing. State adopted the resolution of demolishing the traditional houses and implemented such resolution as a consequence of standard type earthquake houses which do not fit with the cultural life of the region are not preferred by their users. Population who compulsorily started to live in “Earthquake Houses” began to utter their complaints. Even, they attempted to reconstruct and complete their partially demolished houses and returned to live in their traditional old houses. Forwhy, these houses fit with their social lives. Within this context the houses in the village compose of Traditional Houses, Earthquake Houses, houses they developed by being adversely affected from the Earthquake Houses. Each type of housing will be taken up within the scope of the study and their physical, social tissues will be analyzed and scrutinized, and as a result of this detailed study, conception of the region that is transmitted from past to today will be defined. In the study, it is emphasized that traditions which reached from past to today can not be ignored and should be taken into consideration by all means. Within this context, houses located in the region were analyzed as per their periods, opinions of the users were obtained and requests were highlighted in accordance with these findings and the houses which were developed in consequence of the requirements were scrutinized. Outputs were assessed on behalf of protecting the continuity in set- tlement and finalized with the clues of what are the obvious things to be done. For permanence of the settlement it is required to analyze the culture which preserved and protected its existence. Espec

关键词： Housing Earthquake Continuitibility User Demand

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Growth and nitrogen productivity of drip-irrigated winter wheat under different nitrogen fertigation strategies in the North China Plain

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Journal of Integrative Agriculture 2023年第3期22卷 908-922页

作者： Sunusi Amin ABUBAKAR Abdoul kader Mounkaila HAMANI WANG Guang-shuai LIU Hao Faisal MEHMOOD Abubakar Sadiq ABDULLAHI GAO Yang DUAN Ai-wang Key Laboratory of Crop Water Use and Regulation Ministry of Agriculture and Rural Affairs/Farmland Irrigation Research InstituteChinese Academy of Agricultural SciencesXinxiang 453002P.R.China Graduate School of Chinese Academy of Agricultural Sciences Beijing 100081P.R.China Department of Agricultural and Bioresource Engineering Abubakar Tafawa Balewa UniversityBauchi 740272Nigeria

Excessive application of nitrogen (N) fertilizer is the main cause of N loss and poor use efficiency in winter wheat (Triticum aestivum L.) production in the North China Plain (NCP).Drip fertigation is considered to be an effective method for improving N use efficiency and reducing losses,while the performance of drip fertigation in winter wheat is limited by poor N scheduling.A two-year field experiment was conducted to evaluate the growth,development and yield of drip-fertigated winter wheat under different split urea (46%N,240 kg ha^(-1)) *** six treatments consisted of five fertigation N application scheduling programs and one slow-release fertilizer (SRF) *** five N scheduling treatments were N0–100 (0%at sowing and 100%at jointing/booting),N25–75 (25%at sowing and 75%at jointing and booting),N50–50(50%at sowing and 50%at jointing/booting),N75–25 (75%at sowing and 25 at jointing/booting),and N100–0 (100%at sowing and 0%at jointing/booting).The SRF (43%N,240 kg ha^(-1)) was only used as fertilizer at *** N application significantly (P<0.05) affected wheat grain yield,yield components,aboveground biomass (ABM),water use efficiency(WUE) and nitrogen partial factor productivity (NPFP).The N50–50 and SRF treatments respectively had the highest yield(8.84 and 8.85 t ha^(-1)),ABM (20.67 and 20.83 t ha^(-1)),WUE (2.28 and 2.17 kg m^(-3)) and NPFP (36.82 and 36.88 kg kg^(-1)).This work provided substantial evidence that urea-N applied in equal splits between basal and topdressing doses compete economically with the highly expensive SRF for fertilization of winter wheat *** the single-dose SRF could reduce labor costs involved with the traditional method of manual spreading,the drip fertigation system used in this study with the N50–50 treatment provides an option for farmers to maintain wheat production in the NCP.

关键词： split nitrogen strategies wheat yield drip fertigation water use efficiency nitrogen use efficiency

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Comparative characterization and osteogenic/adipogenic differentiation of mesenchymal stem cells derived from male rat hair follicles and bone marrow

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Cell Regeneration 2020年第1期9卷 130-143页

作者： Abdel kader A.Zaki Tariq I.Almundarij Faten A.M.Abo-Aziza Department of Veterinary Medicine College of Agriculture and Veterinary MedicineQassim UniversityBuraydahSaudi Arabia Department of Physiology Faculty of Veterinary MedicineCairo UniversityGizaEgypt Department of Parasitology and Animal Diseases Veterinary Research DivisionNational Research CentreCairoEgypt

Clinical applications of cell therapy and tissue regeneration under different conditions need a multiplicity of adult stem cell *** to date,little is available on the comparative isolation,characterization,proliferation,rapid amplification,and osteogenic/adipogenic differentiation of rat mesenchymal stem cells(MSCs)isolated from living bulge cells of the hair follicle(HF)and bone marrow(BM)from the same *** work hopes to use HF-MSCs as an additional adult stem cell source for research and *** reaching 80%confluence,the cell counting,viability%,and yields of HF-MSCs and BM-MSCs were nearly *** viability%was 91.41±2.98 and 93.11±3.06 while the cells yield of initial seeding was 33.15±2.76 and 34.22±3.99 and of second passage was 28.76±1.01 and 29.56±3.11 for HF-MSCs and BM-MSCs *** of differentiation(CDs)analysis revealed that HF-MSCs were positively expressed CD34,CD73 and CD200 and negatively expressed ***-MSCs were positively expressed CD73 and CD200 and negatively expressed of CD34 and *** proliferation of HFMSCs and BM-MSCs was determined by means of incorporation of Brd-U,population doubling time(PDT)assays and the quantity of formazan *** percentage of Brd-U positive cells and PDT were relatively similar in both types of *** proliferation,as expressed by the quantity of formazan assay in confluent cells,revealed that the quantity of release by BM-MSCs was slightly higher than *** differentiated BM-MSCs showed moderate accumulation of oil red-O stained lipid droplets when compared to that of HF-MSCs which exhibited high *** total lipid concentration was significantly higher in adipogenic differentiated HF-MSCs than BMMSCs(P<0.05).It was found that activity of bone alkaline phosphatase and calcium concentration were significantly higher(P<0.01 and P<0.05 respectively)in osteogenic differentiated BM-MSCs than that of *** present findings demonstrate that the

关键词： Stem cell Bone marrow Hair follicle Osteogenesis Adipogenesis

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General exact solution of the fin problem with variable thermal conductivity

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Propulsion and Power Research 2016年第1期5卷 63-69页

作者： Abass H.Abdel kader Mohamed S.Abdel Latif Hamed M.Nour Engineering Mathematics and Physics Department Faculty of EngineeringMansoura UniversityMansoura 35516Egypt

In this paper,Lie point symmetry method is used to obtain the general exact solution of the second order nonlinear ordinary differential equation which goveming heat transfer in rectangular fin with variable thermal *** new forms of thermal conductivity are introduced and the associated exact solution is obtained in each *** general relation among the fin efficiency,thermal conductivity and thermo-geometric parameter is obtained.

关键词： Exact solution Fin Thermal conductivity Heat transfer Lie point symmetry

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