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Hypotensive Effects of an Aqueous Extract of Bambusa vulgaris (Poaceae) Leaves in Rabbit Oryctolagus cuniculus

Journal of Biosciences and Medicines 2023年第8期11卷 51-59页

作者： Appy Simone Abé Kouao Augustin Amonkan kacou jules marius djétouan Koffi Joseph N’guessan N’dah Etchien Christelle Ekra Kesse Philippe N’da Koffi Bruno Koko Akoua Jeanne Kanga UPR-Nutrition and Pharmacology Laboratory of Biology and Health UFR-Biosciences Félix Houphou&eumlt-Boigny University Abidjan C&otildete d’Ivoire UPR-Animal Physiology Phytotherapy and Pharmacology Laboratory of Biology and Health UFR-Biosciences Félix Houphou&eumlt-Boigny University Abidjan C&otildete d’Ivoire Laboratory of Industrial Processes Synthesis Environment and New Energy (LAPISEN) Institute National Polytechnique Félix Houphou&eumlt-Boigny Yamoussoukro C&otildete d’Ivoire

Plant of Bambusa vulgaris is used in traditional medicine practice for the management of many pathologies including hypertension. The effect of the aqueous extract of the leaves of Bambusa vulgaris on blood pressure was evaluated in normotensive male rabbits. Blood pressure was measured by the invasive method. Thus, aqueous extract of Bambusa vulgaris leaves had been injected intravenously at doses ranging from 1 mg/kg to 30 mg/kg in rabbits anesthetized with thiopental. The effects of this extract on blood pressure were also evaluated in rabbits having previously received different doses of atropine. The aqueous extract of Bambusa vulgaris leaves induced a dose-dependent hypotension which is not canceled in the presence of atropine. The results obtained show that the extract has blood pressure lowering effect which may be mediated by muscarinic-type cholinergic receptors.

关键词： Bambusa vulgaris Aqueous Extract Hypotensive Effects Oryctolagus cuniculus Rabbits Atropine

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Galactagogue Effect of <i>Euphorbia hirta</i>(Euphorbiaceae) Aqueous Leaf Extract on Milk Production in Female Wistar Rats

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Journal of Biosciences and Medicines 2019年第9期7卷 51-65页

作者： Buno Koffi Koko André Brou Konan Flora Kouamé Amoin Kouacou jules marius kacou djétouan Augustin Kouao Amonkan Laboratoire de Nutrition et Pharmacologie UFR-Biosciences Université Félix HOUPHOU&Euml T-BOIGNY Abidjan C&ocirc te d’Ivoire

Background: Populations of Gontougo (C?te d’Ivoire) commonly used Euphorbia hirta (Euphorbiaceae) leaves as galactagogue to boost milk production in lactating women. Our study was carried to verify this traditional belief via evaluations of milk production, serum prolactin levels, body weight and mammary lobuloalveolar proliferation induced by the aqueous leaf extract of this medicinal plant in Wistar rats. Methods: 6 groups of 6 virgin rats and 6 groups of 6 lactating rats were used. Each lactating rat was isolated with its six pups. These groups of animals were treated orally with distilled water, Metoclopramide (Metocl 5 mg/kg) and E. hirta aqueous leaf extract (EHae 100, 200, 400 and 600 mg/kg) daily during 17 days of lactation. The indirect method which assimilates the weight gain of untreated pups to the quantity of milk produced by lactating rats was used. At the end of the treatment, histological sections of the abdominal mammary glands of lactating rats were observed. Results: EHae administration induced an increase of milk production in lactating rats. This action of EHae was stronger at the dose of 200 mg/kg. Milk production of the treated rats at a dose of 200 mg/kg was 118.14 ± 1 g. The quantity of milk produced by the control female rats was 83.83 ± 0.88 g. Compared with the control, EHae 200 mg/kg significantly increased milk production (40.92%) (P Conclusion: EHae showed a galactagogue activity illustrated by increases of milk production, PRL secretions and the development of the lobuloalveolar system of the mammary glands in treated female rats. This galactagogue property could partly justify the traditional use of this plant to boost milk production in lactating women.

关键词： Euphorbia hirta Metoclopramide Galactagogue Effect Prolactin Milk Production

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Desorption of Methylene Blue Adsorbed on Activated Carbon from Cocoa Pod Shell

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Open Journal of Applied Sciences 2023年第5期13卷 605-617页

作者： David Léonce Kouadio Yapo Aristide Hermann Yapi djedjess Essoh jules César Meledje kacou Alain Paterne Dalogo djamatché Paul Valery Akesse Brou Dibi Karim Sory Traore Laboratoire des Sciences et Technologie de l’Environnementale Université Jean Lorougnon Guede C&#244te d’Ivoire Laboratoire des Sciences Physiques Fondamentales et appliquées école Normale Supérieure (Abidjan) Abidjan C&#244te d’Ivoire Laboratoire des Sciences de l’Environnement Université Nangui Abrogoua C&#244te d’Ivoire

Environmental protection has become a concern for the world. For this reason, the objective of this work is to remove methylene blue adsorbed on activated carbon. The coal used comes from cocoa pod shells. Before pyrolysis, the shells were ground, sieved and impregnated with orthophosphoric acid. Before desorption, the activated carbons were initially saturated with MB. These saturated coals were brought into contact with a sodium chloride (NaCl) solution and then stirred. The evolution of the resorbed MB concentration was monitored by spectrophotometry. The desorption tests showed a remarkable elimination from the first 10 minutes. The desorption kinetics comprises two phases: a rapid kinetics between 0 and 30 minutes and a slow kinetics between 30 and 60 minutes. The desorption of the dye reaches a concentration aqual to 0.84 mg/l at pH = 4 at temperature = 80°C. For modeling, the coefficient of the Langmuir II model is greater than or equal to O.9893. The model of Langmuir III is less than or equal to 0.9373. The Freundlich model coefficient is 0.9842 or less. The desorption is thefore carried out on energy-homogeneous adsorption sites and without any interaction between the adsorbed cations of the dye. Experimental parameters such as pH, temperature and concentration of sodium chloride (NaCl) solution influence the desorption of MB. And the model of Langmuir II describes well the process of desorption of the MB.

关键词： Desorption Activated Carbon Methylene Blue Isotherm Sodium Chloride

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