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Journal of Immune Based Therapies, Vaccines and Antimicrobials 2024年第1期13卷 1-15页

作者： Papa Djibril Ndoye Lebem Togtoga Abdourahmane Ndong Mamadou saïdou Bah Khadim Niang Departement of Public Health and Social Medicine UFR of Health Science Gaston Berger University Saint-Louis Senegal ENDA sant Dakar Senegal

Introduction: The HPV vaccine was included in the Expanded Programme on Immunisation in Senegal in 2018. However, vaccination coverage is still low among targeted girls. The aim of this research was to study the factors associated with vaccine uptake among girls aged 9 - 14 years in the Langue de Barbarie area of saint-Louis, Senegal. Methodology: This was a descriptive and analytical cross-sectional study. The sample size was calculated using the Schwartz formula and distributed proportionally to the size of the population in the neighborhoods. Data were collected from 2nd to 19th January 2024 from mothers or guardians of girls aged 9 to 14 using anonymous questionnaires configured on tablets with Survey 123 software and analysed using R software. Results: A total of 799 people were interviewed. The average age of the respondents was 35.67 years, with a standard deviation of 7.08 and a range of 17 and 49 years. Reported vaccination coverage was 41.9%. Factors positively correlated with vaccination included: attendance at primary school or daara (OR = 2.50 [CI: 1.43 - 4.48] and OR = 2.05 [CI: 1.09 - 3.94]), information about vaccination (OR = 6.64 [CI: 4.59 - 9.72]), history of cervical cancer screening among mothers or guardians (OR = 6.64 [CI: 4.59 - 9.72]). Conclusion: Identifying the factors associated with HPV vaccination is necessary to assess and improve the vaccination strategy in order to improve vaccination coverage among targeted girls.

关键词： Cervical Cancer Vaccine HPV Girls Risk Senegal

Study on the Knowledge of Mothers or Guardians of Girls Aged 9 - 14 from the Langue de Barbarie in saint-Louis, Senegal about Cervical Cancer and Its Relationship to HPV Vaccination in 2024

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Journal of Immune Based Therapies, Vaccines and Antimicrobials 2024年第2期13卷 17-31页

Introduction: The relationship between knowledge of HPV and vaccination has been established. The aim of this study was to investigate the knowledge of mothers or guardians of girls aged 9 - 14 about cervical cancer and their attitudes to HPV vaccination. Methodology: This was a descriptive cross-sectional survey. The sample size was calculated using the Schwartz formula and distributed proportionally to the size of the neighbourhood population. Data was collected between 2nd to 19th January 2024 using anonymous questionnaires configured on tablets with Survey 123 software and analysed using R software. Results: A total of 799 people were interviewed. The average age of the respondents was 35.67 years, with a standard deviation of 7.08 and a range of 17 and 49 years. The information channels for cervical cancer were the media (82.8%), health facilities (47.7%) and community intermediaries (23.3%). Only 53.7% had information about the vaccine and 25.5% about the vaccination strategy. The main reason for accepting the vaccine was awareness of the seriousness of cervical cancer (55.1%). Conclusion: It is essential to take stock of knowledge about cervical cancer and attitudes to vaccination to assess the impact of interventions and redirect strategies to improve vaccination coverage. .

关键词： Cervical Cancer HPV Vaccine Knowledge Girls Senegal

The effect of reactive plasticizer on viscoelastic and mechanical properties of solid rocket propellants based on different types of HTPB resin

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Defence Technology（防务技术） 2024年第3期33卷 66-77页

作者： Tihomir Kovacevic Slavko Mijatov Jelena Grzetic Suzana Cakic Bojana Fidanovski sasa Brzic Military Technical Institute Ministry of DefenceRatka Resanovica 1BelgradeSerbia Faculty of Technology University of NisBulevar osloboCenja 124LeskovacSerbia

Conventional plasticizers deteriorate mechanical and viscoelastic properties of the propellants due to their migration upon aging and long-term storage,which affects reliability and safety properties during *** address this issue,conventional plasticizer,dioctyl adipate(DOA),is replaced by reactive one,castor oil(CO).In addition,three different types of HTPB were used to obtain propellants with designed viscoelastic and mechanical *** CO increased propellants viscosity,without a significant impact on the propellant processability,regardless to the type of ***,mechanical properties were different depending on the type of resin,which were further analyzed by gel permeation chromatography(GPC).Addition of CO formed a denser polymer network and shifted T_(g) to higher values,compared to the compositions with *** tensile strength of CO-containing propellants was lower at +20℃ and +50℃ compared to the reference compositions,while the strain at maximum load and strain at break were significantly increased with pronounced plastic deformation,especially for samples at -30℃.The inclusion of CO in the propellants composition gives more room for adjusting a wide range of mechanical properties.

关键词： HTPB-based composite propellants Castor oil Reactive plasticizer Gel permeation chromatography Sol-gel analysis Mechanical and viscoelastic properties

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激光散射特性的红外瞄准镜基线检测方法

激光杂志 2024年第7期45卷 227-232页

作者：李波莎日娜内蒙古医科大学呼和浩特010110 中国人民解放军32302部队50分队北京101400

为提升武器射击精度,设计激光散射特性的红外瞄准镜基线检测方法。通过固定瞄准镜并利用黑体发射红外激光,在镜子反射后形成红外平行光束,并在瞄准镜视场内生成靶标的像。通过调整瞄准镜分划中心与靶标像中心重合,实现基线检测。采用双... 详细信息

为提升武器射击精度,设计激光散射特性的红外瞄准镜基线检测方法。通过固定瞄准镜并利用黑体发射红外激光,在镜子反射后形成红外平行光束,并在瞄准镜视场内生成靶标的像。通过调整瞄准镜分划中心与靶标像中心重合,实现基线检测。采用双向反射分布函数和基尔霍夫近似理论的驻留相位近似法,分析红外激光的散射特性及波长与散射角对成像精度的影响,从而提高基线检测的精度。实验证明:当入射波长在9.5μm左右时,射击目标粗糙度为8μm时,双站极化散射系数最低,在1.0左右;当散射角在29°左右时,射击目标粗糙度为8μm时,双站极化散射系数最低在0.146左右;校正后目标位置偏差平均为0.01 m。

关键词：激光散射特性红外瞄准镜基线检测反射分布函数基尔霍夫驻留相位近似法

Development of a new Cox model for predicting long-term survival in hepatitis cirrhosis patients underwent transjugular intrahepatic portosystemic shunts

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World Journal of Gastrointestinal Surgery 2024年第2期16卷 491-502页

作者： Yi-Fan Lv Bing Zhu Ming-Ming Meng Yi-Fan Wu Cheng-Bin Dong Yu Zhang Bo-Wen Liu Shao-Li You sa Lv Yong-Ping Yang Fu-Quan Liu Liver Disease Minimally Invasive Diagnosis and Treatment Center Beijing Shijitan HospitalCapital Medical UniversityBeijing 100038China Liver Vascular Disease Diagnosis and Treatment Center The Fifth Medical Center of Chinese People's Liberation Army General HospitalBeijing 100039China

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)placement is a procedure that can effectively treat complications of portal hypertension,such as variceal bleeding and refractory ***,there have been no specific studies on predicting long-term survival after TIPS *** To establish a model to predict long-term survival in patients with hepatitis cirrhosis after *** A retrospective analysis was conducted on a cohort of 224 patients who un-derwent TIPS *** univariate and multivariate Cox regression analyses,various factors were examined for their ability to predict survival at 6 years after ***,a composite score was formulated,encompassing the indication,shunt reasonability,portal venous pressure gradient(PPG)after TIPS,percentage decrease in portal venous pressure(PVP),indocyanine green retention rate at 15 min(ICGR15)and total bilirubin(Tbil)***,the performance of the newly developed Cox(NDC)model was evaluated in an in-ternal validation cohort and compared with that of a series of existing *** The indication(variceal bleeding or ascites),shunt reasonability(reasonable or unreasonable),ICGR15,post-operative PPG,percentage of PVP decrease and Tbil were found to be independent factors affecting long-term survival after TIPS *** NDC model incorporated these parameters and successfully identified patients at high risk,exhibiting a notably elevated mortality rate following the TIPS procedure,as observed in both the training and validation ***,in terms of predicting the long-term survival rate,the performance of the NDC model was significantly better than that of the other four models[Child-Pugh,model for end-stage liver disease(MELD),MELD-sodium and the Freiburg index of post-TIPS survival].CONCLUSION The NDC model can accurately predict long-term survival after the TIPS procedure in patients with hepatitis cirrhosis,help identify high-risk patients

关键词： Transjugular intrahepatic portosystemic shunt Long-term survival Predictive model

A Registry-Based Observational Study on the Maternal and Fetal Outcomes of COVID-19 Patients in Hong Kong,China

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Maternal-Fetal Medicine 2024年第3期6卷 156-163页

作者： Hillary HY Leung Teresa WL Ma Florrie NY Yu Meliza CW Kong Tsz Kin Lo Pauline PL So Wing-Cheong Leung Wendy Shu ka Wang Cheung sakita Moungmaithong Chi Chiu Wang Liona C.Poon Department of Obstetrics and Gynaecology The Chinese University of HongKongHong Kong 999077China Department of Obstetrics and Gynaecology Queen Elizabeth HospitalHong Kong 999077China Department of Obstetrics and Gynaecology United Christian HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Princess Margaret HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Tuen Mun HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Kwong Wah HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Pamela Youde Nethersole Eastern HospitalHong Kong 999077China Department of Obstetrics and Gynaecology Queen Mary HospitalHong Kong 999077China

Objective:To report the clinical maternal and fetal outcomes of pregnant women with coronavirus disease 2019(COVID-19),along with any associated pregnancy complications,in Hong Kong,China,and to assess the impact of COVID-19 vaccination on these ***:This prospective registry-based observational study included pregnant women who were recruited through convenient sampling and had a laboratory-confirmed severe acute respiratory syndrome coronavirus 2 infection with a cycle threshold(Ct)value result available on admission to eight local hospitals in Hong Kong,*** on clinical symptoms,laboratory results,medical treatments,delivery timing and mode,and pregnancy complications were extracted from the Hospital Authority’s electronic medical record ***,fetal,and pregnancy outcomes were compared between unvaccinated pregnant women with COVID-19 and those who had received at least one dose of COVID-19 vaccine before *** continuous variables and categorical variables were analyzed using the Mann-Whitney U test and the Pearson’s chi-squared test respectively.A P value less than 0.05 was considered statistically ***:A total of 164 pregnant women were included,of whom 78(47.56%)were ***-19 was diagnosed before 28 weeks’gestation in 30(18.29%),while 134(81.71%)were diagnosed at or after 28 weeks’***-two(37.80%)women received at least one dose of COVID-19 *** were no significant differences between vaccinated and unvaccinated groups in the time interval between COVID-19 diagnosis and delivery,the Ct value,and the gestational age at infection onset or delivery(P>0.05).The majority of women were symptomatic at diagnosis regardless of vaccination status 55(88.71%)in vaccinated group vs.78(76.47%)in unvaccinated group(P=0.052).Symptoms did not significantly differ between groups except for cough(62.90%vs.47.06%,P=0.049).The overall rate of severe COVID-19 in pregnant women was *** t

关键词： COVID-19 Maternal outcomes Fetal outcomes Pregnancy complications Severe COVID-19

Britanin–a beacon of hope against gastrointestinal tumors?

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World Journal of Clinical Oncology 2024年第4期15卷 523-530页

作者： Agnieszka kajdanek Damian Kołat Lin-Yong Zhao Mateusz Kciuk Zbigniew Pasieka Żaneta kałuzińska-Kołat Department of Biomedicine and Experimental Surgery Medical University of LodzLodz 90-136LodzkiePoland Department of Functional Genomics Medical University of LodzLodz 90-752LodzkiePoland Department of General Surgery&Laboratory of Gastric Cancer State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy and Cancer CenterWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Gastric Cancer Center West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Molecular Biotechnology and Genetics University of LodzLodz 90-237LodzkiePoland

Britanin is a bioactive sesquiterpene lactone known for its potent anti-inflammatory and anti-oxidant *** also exhibits significant anti-tumor activity,suppressing tumor growth in vitro and in *** current body of research on Britanin includes thirty papers predominantly related to neoplasms,the majority of which are gastrointestinal tumors that have not been summarized *** drive academic debate,the present paper reviews the available research on Britanin in gastrointestinal *** also outlines novel research directions using data not directly concerned with the digestive system,but which could be adopted in future gastrointestinal *** was found to counteract liver,colorectal,pancreatic,and gastric tumors,by regulating proliferation,apoptosis,autophagy,immune response,migration,and *** confirmed in pancreatic,gastric,and liver cancer,its most commonly noted molecular effects include nuclear factor kappa B and B-cell lymphoma 2 downregulation,as well as Bcl-2-associated X protein ***,it has been found to induce the Akt kinase and Forkhead box O1 axis,activate the AMP-activated protein kinase pathway,elevate interleukin-2 and peroxisome proliferator-activated receptor-γlevels,reduce interleukin-10,as well as downregulate matrix metalloproteinase-9,Twist family bHLH transcription factor 1,and *** also inhibits Myc–HIF1αinteraction and programmed death ligand 1 transcription by interrupting the Ras/RAF/MEK/ERK pathway and mTOR/P70S6K/4EBP1 *** research should aim to unravel the link between Britanin and acetylcholinesterase,mast cells,osteolysis,and ischemia,as compelling data have been provided by studies outside the gastrointestinal *** the cytotoxicity of Britanin on noncancerous cells is significantly lower than that on tumor cells,while still being effective against the latter,further in-depth studies with the use of animal models are *** compound exhi

关键词： Britanin Sesquiterpene lactones Chemotherapeutics Gastrointestinal tumors In vitro In vivo

Non-thermal atmospheric-pressure positive pulsating corona discharge in degradation of textile dye Reactive Blue 19 enhanced by Bi_(2)O_(3) catalyst

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Plasma Science and Technology 2024年第2期26卷 104-113页

作者： Milica PETROVIC Dragan RADIVOJEVIC sasa RANCEV Nena VELINOV Milos KOSTIC Danijela BOJIC Aleksandar BOJIC Department of Chemistry Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia Department of Physics Faculty of Sciences and MathematicsUniversity of NisNis 18000Serbia

In this work,monoclinic Bi_(2)O_(3) was applied for the first time,to the best of our knowledge,as a catalyst in the process of dye degradation by a non-thermal atmospheric-pressure positive pulsating corona *** research focused on the interaction of the plasma-generated species and the catalyst,as well as the role of the catalyst in the degradation *** decomposition of the anthraquinone reactive dye Reactive Blue 19(RB 19) was performed in a selfmade reactor ***_(2)O_(3) was prepared by electrodeposition followed by thermal treatment,and characterized by x-ray diffraction,scanning electron microscopy and energy-dispersive xray *** was observed that the catalyst promoted decomposition of plasma-generated H_(2)O_(2) into ·OH radicals,the principal dye-degrading reagent,which further attacked the dye *** catalyst improved the decolorization rate by 2.5 times,the energy yield by 93.4%and total organic carbon removal by 7.1%.Excitation of the catalyst mostly occurred through strikes by plasma-generated reactive ions and radical species from the air,accelerated by the electric field,as well as by fast electrons with an energy of up to 15 eV generated by the streamers reaching the liquid *** strikes transferred the energy to the catalyst and created the electrons and holes,which further reacted with H_(2)O_(2) and water,producing ·OH *** was indentified as the primary role of the catalyst in this *** reactions followed pseudo first-order *** of H_(2)O_(2) and the dye degradation rate increased with increase in the input *** optimal catalyst dose was 500 mg·dm^(-3).The decolorization rate was a little lower in river water compared with that in deionized water due to the side reactions of ·OH radicals with organic matter and inorganic ions dissolved in the river water.

关键词： corona RB 19 Bi_(2)O_(3) catalyst degradation

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非物质文化遗产保护中习惯规则的价值探析

贵州民族研究 2024年第2期45卷 171-176页

作者：萨矗荣贵中国人民大学法学院北京100872

非物质文化遗产本身蕴含着丰富的习惯规则内容,这些传统的习惯规则在文化传承中发挥着正式规范所无法替代的作用。习惯规则主要通过口头传承的方式得以延续,并由习惯机构依据传统社区和群体的文化价值观执行,旨在保护非物质文化遗产的... 详细信息

非物质文化遗产本身蕴含着丰富的习惯规则内容,这些传统的习惯规则在文化传承中发挥着正式规范所无法替代的作用。习惯规则主要通过口头传承的方式得以延续,并由习惯机构依据传统社区和群体的文化价值观执行,旨在保护非物质文化遗产的社会和文化利益,确保群体内成员享有平等的权利义务。根据传统习惯,非遗是集体所共有的,其使用伦理依赖于习惯规则和群体内部的社会关系。因此习惯规则在保护集体权利方面发挥着重要作用。沿袭多年的习惯规则与非遗所在的地域和群体紧密相连,与现代法治互补并存,共同发挥作用。在非遗保护价值观上,二者的一致性能使它们相互呼应,共同维护非遗的传承与发展。

关键词：习惯规则集体利益合理使用现代价值

从《沈阳百咏》探析光绪初年盛京城人居文化景观

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风景园林 2024年第6期31卷 133-139页

作者：谢淼伊娜王飒沈阳建筑大学建筑与规划学院沈阳建筑大学辽宁省区域建筑学与寒地人居科学重点实验室

【目的】从人居环境学的角度,探究在清末外部变化影响下仍是帝国陪都的盛京城内文化景观和城市空间变化,以填补盛京城清末文化景观研究的不足。【方法】以《沈阳百咏》为依据,运用文本挖掘语义分析、时间地理学分析、历史地理空间分析... 详细信息

【目的】从人居环境学的角度,探究在清末外部变化影响下仍是帝国陪都的盛京城内文化景观和城市空间变化,以填补盛京城清末文化景观研究的不足。【方法】以《沈阳百咏》为依据,运用文本挖掘语义分析、时间地理学分析、历史地理空间分析量化光绪初年盛京城人居文化景观类型和时空信息,探讨文化景观的分布规律,并通过对比清朝前、中、末期城市空间,总结光绪初年盛京城的风貌特点。【结果】将盛京城人居文化景观归纳为“游憩玩赏”“盛京旧制”“市井生活”“信俗集会”4个一级分类及15个二级分类,发现文化景观类型与季节农时有强关联,不同文化景观在地理空间分布上有显著差异,整体上集中于关厢地带,城北景观密度高于城南。通过将《沈阳百咏》中城市空间与清前、中期城市空间对比发现,光绪初年盛京城已成为有满族特色的地方中心性城市。【结论】对《沈阳百咏》的深入挖掘填补了清末盛京城文化景观研究的缺环,为清代盛京城研究提供新思路,同时也为后续通过诗文分析盛京城文化景观格局提供了参考。

关键词：文化景观人居环境学诗词文本挖掘时空结构清代盛京城