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Science China Earth Sciences 2009年第3期52卷 360-368页

作者： l. R. EDWARDS Department of Geology and Geophysics University of Minnesota Minneapolis

A stalagmite-based isotope record (No. H82) from Nanjing Hulu Cave, spanning from 16.5 to 10.3 ka BP, provided strong evidence for a coherence relation between the East Asian summer monsoon (EASM) and the North Atlant... 详细信息

关键词： Nanjing Hulu Cave stalagmite East Asian summer monsoon event

A Climatic Utility Index for the Analysis of the Expected Changes of Cherry and Sour Cherry Production in Central Hungary,Regarding Climate Change

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A Climatic Utility Index for the Analysis of the Expected Ch...

Pandemic of the aging society—sporadic cerebral small vessel disease

2012 International Conference on Future Environment and Energy（ICFEE 2012）

作者： Márta Gaál Károly Szenteleki Zoltán Mézes Réka Homoródi Márta ladány Corvinus University of Budapest H-1118 Budapest Villányi út 29 Hungary University of Debrecen H-4032 Debrecen B sz rményi út 138. Hungary

Production security and risk of a given plant are basically determined by climatic factors the change of which is a great challenge for the *** paper focuses on the climatic conditions of cherry and sour cherry production in Central Hungary in three time periods:1961-1990 as a reference,2021-2050 as the near future and 2071-2100 for the long-term analysis.A climatic utility index is introduced based on climatic factors and experts’ suggestions and *** future changes are evaluated by using the predictions of regional climate model RegCM3.1 downscaled to the Carpathian *** show that in the near future fruit cracking risk of cherry could be higher,but in overall the expected changes are mostly favourable for both cherry and sour cherry production in *** the end of the century irrigation may be required to maintain the production security and the high standard quality of *** is also advised to re-evaluate the varieties according to the indicated changes,as a new orchard planted nowadays will have many productive years in the considered future periods.

关键词： climate change cherry production sour cherry production climatic risk climatic year types climatic utility index

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Chinese Medical Journal 2021年第2期134卷 143-150页

作者： Alexander Yuk lun lau Bonaventure Yiu Ming Ip Ho Ko Bonnie Yin ka lam lin Shi karen ka Yan Ma lisa Wing Chi Au Yannie Oi Yan Soo Thomas Wai Hong leung Adrian Wong Vincent Chung Tong Mok Division of Neurology Department of Medicine and TherapeuticsThe Faculty of MedicineThe Chinese University of Hong KongHong KongChina Gerald Choa Neuroscience Centre Faculty of MedicineLui Che Woo Institute of Innovative MedicineThe Chinese University of Hong KongHong KongChina Faculty of Medicine School of Biomedical SciencesLi Ka Shing Institute of Health SciencesThe Chinese University of Hong KongHong KongChina Margaret Cheung K.l.Cheung Research Centre for Management of Parkinsonism Faculty of MedicineThe Chinese University of Hong KongHong KongChina Department of Imaging and Interventional Radiology The Chinese University of Hong KongHong KongChina Shenzhen Research Institute The Chinese University of Hong KongShenzhenGuangdongChina.

Age-related sporadic cerebral small vessel disease(CSVD)has gained increasing attention over the past decades because of its increasing prevalence associated with an aging *** widespread application of and advances in brain magnetic resonance imaging in recent decades have significantly increased researchers’understanding in the in vivo evolution of CSVD,its impact upon the brain,its risk factors,and the mechanisms that explain the various clinical manifestation associated with sporadic *** this review,we aimed to provide an update on the pathophysiology,risk factors,biomarkers,and the determinants and spectrum of the clinical manifestation of sporadic CSVD.

关键词： Cerebral small vessel disease Clinical spectrum Pathophysiology

推按运经仪治疗脑卒中的效果:与针灸治疗的随机分组比较

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中国临床康复 2006年第19期10卷 4-5,8页

作者：李应昆吴节胡卡明黄绿成都中医药大学附属医院针灸科四川省成都市610072 成都中医药大学针灸推拿学院四川省成都市610075

目的:观察推按运经仪治疗脑卒中的临床疗效,并与传统针灸疗法进行对比。方法:①选择1998-08/1999-06成都中医药大学附属医院针灸科住院脑卒中患者30例。均对治疗方案知情同意。②按信封法随机分为2组:推按运经仪治疗组、针刺治疗组,各1... 详细信息

目的:观察推按运经仪治疗脑卒中的临床疗效,并与传统针灸疗法进行对比。方法:①选择1998-08/1999-06成都中医药大学附属医院针灸科住院脑卒中患者30例。均对治疗方案知情同意。②按信封法随机分为2组:推按运经仪治疗组、针刺治疗组,各15例。推按运经仪治疗组:采用北京密波自动化控制设备厂生产的推按运经仪。将仪器5个极板分别置于患侧肢体阳经穴位:肩、臂臑、曲池、外关、合各、环跳、髀关、果丘、昆仑、足三里,选用频率50～100Hz、输出量60%～90%,以患者耐受为度。治疗30min/次,1次/d,30d为1疗程。针灸治疗组:根据“治萎独取阳明”的原则,采用常规针刺法治疗。选穴与治疗组相同,针用平补平泻,得气后留针30min,1次/d,30d为1疗程。两组均治疗1个疗程。③采用脑卒中评分穴包括7项内容:神志状态、语言表达、上肢肩关节、指关节、髋关节、趾关节、综合功能,5级评分:0～4分,分数越高病情越轻雪评估患者病情。④根据治疗1疗程前后脑卒中评分变化判定疗效:恶化:病情加重积分减少或死亡者;无效:积分增加0.05演。结论:推按运经仪能有效治疗脑卒中,效果与传统针灸疗法相当。

关键词：脑血管意外/按摩疗法脑血管意外/针灸疗法推按运经仪

Sheng Jiang San, traditional multi-herb formulation, exerts anti-influenza effects in vitro and in vivo via neuraminidaseinhibition and immune regulation

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中国药理学与毒理学杂志 2019年第9期33卷 738-739页

作者： ZHANG Tian-bo XIAO Meng-jie Chun-Kwok WONG ka-Pun CHRIS MOK ZHAO Xin TI Hui-hui Pang-Chui SHAW State Key laboratory of Respiratory Disease Guangdong Provincial Key Laboratory of Molecular Target&Clinical PharmacologySchool of Pharmaceutical Sciences and The Fifth Affiliated HospitalGuangzhou Medical UniversityGuangzhouChina The School of life Sciences The Chinese University of Hong KongHong KongChina School of Public Health Li Ka Shing Faculty of MedicineThe University of Hong KongHong KongChina

OBJECTIVE Sheng Jiang San(SJS),a multi-herb formulation,is used in treating high fever,thirsty and anxiety in ancient China and it is sometimes used to treat seasonal influenza in ***,there is no evidencebased investigation and mechanism research to support SJS′s anti-influenza *** study aims to investigate the anti-influenza effect of SJS and its possible *** In this study,we examined the inhibitory effect of SJS against different influenza viruses on Madin-Darby canine kidney *** virus infected BAlB/c mice were employed as in vivo model to evaluate the *** challenged with A/PR/8/34(H1N1)were orally administrated SJS 1 g·kg^-1 daily for seven days and monitored for 14 *** survival rate,body mass changes,lung index,lung viral load,histopathologic changes and immune-regulation of the mice were *** underlying anti-influenza virus mechanisms were studied by a series of biological assays in vitro to determine if hemagglutinin,ribonucleoprotein complex or nerauminidase were targets of *** SJS exerted a broad spectrum of inhibitory effects on multiple influenza strains in a dose-dependent *** IC50 of SJS against A/WSN/33(H1N1)was lower than 35 mg·l^-*** also protected 50%of mice from influenza virus PR8 *** lung index and the lung viral load of SJS treated mice were signifi⁃cantly decrease compared with untreated *** 2 g·l^-1 inhibited 80%of neuraminidase enzymatic *** also up-regulated TNF-αand IFN-αand down-regulated Il-2 of influenza virus induced *** SJS is a useful formulation for treating influenza virus infection.

关键词： Sheng Jiang San anti-influenza activity neuraminidase inhibition immuno-regulation

CSF-1-dependant Bone Marrow Derived Macrophages Mediate Chronic Graft-Versus-Host Disease

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CSF-1-dependant Bone Marrow Derived Macrophages Mediate Chro...

第九届全国免疫学学术大会

作者： Alexander ka Flynn R lineburg KE Kuns RD Teal BE Olver SD lor M Raffelt NC Koyama M leveque l le Texier l Melino M Markey ka Varelias A Engwerda CR Serody J Janela B Ginhoux F Clouston AD Blazar BR Hill GR MacDonald KPA QIMR Berghofer Medical Research Institute Brisbane4006Australia Pediatric Blood and Marrow Transplantation Program University of MinnesotaMinneapolisMN 55454USA lineberger Comprehensive Cancer Center University of North Carolina School of MedicineChapel HillNCUSA Singapore Immunology Network(SIgN) A*STAR(Agency for ScienceTechnology and Research)Biopolis138648 Singapore Department of Bone Marrow Transplantation Royal Brisbane HospitalBrisbane4006Australia

Chronic GVHD(cGVHD)is the major cause of late non-relapse death following stem cell transplantation which targets organs such as skin and *** multiple models of cGVHD we investigated the role of macrophages in the development of *** an established Il-17 dependent sclerodermatous cGVHD model,we confirmed that macrophages

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基于常规处理工艺水中铊污染应急处理研究

给水排水 2021年第8期47卷 28-31,78页

作者：朱敏卞卡株洲市水务投资集团有限公司株洲412000

由于湘江水体出现铊含量超过《地表水环境质量标准》(GB 3838—2002)规定限值0.0001 mg/l的现象,以湘江为水源的自来水厂供水安全受到威胁。为了保障供水水质安全,在株洲市某水厂进行了一系列的生产性试验,发现预氯化+强化混凝的方法对... 详细信息

由于湘江水体出现铊含量超过《地表水环境质量标准》(GB 3838—2002)规定限值0.0001 mg/l的现象,以湘江为水源的自来水厂供水安全受到威胁。为了保障供水水质安全,在株洲市某水厂进行了一系列的生产性试验,发现预氯化+强化混凝的方法对水中铊有较好的处理效果。结果表明:通过增加预处理加氯量,将沉淀出水余氯控制在0.4 mg/l以上,浊度控制在2.0 NTU以下,经砂滤池过滤后,水中铊含量明显降低,铊的去除率最高达93.94%,出厂水满足《生活饮用水卫生标准》(GB 5749—2006)的要求。该方法利用水厂现有常规处理工艺,无需增加或改造应急投加设施,通过调整运行参数,即可取得较好的除铊效果。

关键词：源水突发性污染预氯化强化混凝铊

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正交试验优选双葛止泻颗粒一步制粒工艺

中国兽药杂志 2024年第9期58卷 52-57页

作者：李焕娟周冰段飞燕桑卡娜张晓会刘雅菲陈帅韬周德刚洛阳惠中兽药有限公司河南洛阳471000

本试验旨在优选双葛止泻颗粒一步制粒工艺,为双葛止泻颗粒研制与产业化提供理论依据。以浸膏的相对密度、进风温度、输液频率和雾化压力为考察因素,以合格颗粒的收率和休止角为综合评价指标,采用l_(9)(3^(4))正交试验法,对双葛止泻颗粒... 详细信息

本试验旨在优选双葛止泻颗粒一步制粒工艺,为双葛止泻颗粒研制与产业化提供理论依据。以浸膏的相对密度、进风温度、输液频率和雾化压力为考察因素,以合格颗粒的收率和休止角为综合评价指标,采用l_(9)(3^(4))正交试验法,对双葛止泻颗粒一步制粒工艺进行优化,并进行三批工艺验证。结果显示,最优制粒参数为:浸膏的相对密度为1.20(70℃),进风温度为70℃,输液频率为4 Hz,雾化压力为0.15 MPa。结果表明,优选的双葛止泻颗粒一步制粒工艺稳定,重复性好,可用于工业化生产。

关键词：双葛止泻颗粒一步制粒正交试验

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新元公司无煤柱开采充填技术应用与推广

煤 2021年第4期30卷 22-24,57页

作者：吕杰卞卡山西新元煤炭有限责任公司山西寿阳045400 扬州中矿建筑新材料科技有限公司江苏仪征211400

文章介绍了阳煤集团新元公司无煤柱开采技术应用的背景与生产地质条件,通过高水材料巷旁充填沿空留巷技术在高瓦斯突出煤层松软围岩条件下的成功试验,工作面由原来的“U+l”通风方式优化成“Y”型通风方式,目前矿井3号煤所有工作面实现... 详细信息

文章介绍了阳煤集团新元公司无煤柱开采技术应用的背景与生产地质条件,通过高水材料巷旁充填沿空留巷技术在高瓦斯突出煤层松软围岩条件下的成功试验,工作面由原来的“U+l”通风方式优化成“Y”型通风方式,目前矿井3号煤所有工作面实现无煤柱开采,高水材料巷旁充填技术在新元公司及阳煤集团得到广泛推广。

关键词：高水材料高瓦斯突出无煤柱开采 “Y”型通风

Hyperuricemia in Patients with Chronic Renal Failure in the General Hospital of National Reference of N’Djamena (Chad)

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Open Journal of Nephrology 2017年第1期7卷 9-18页

作者： Guillaume Mahamat Abderraman Ibrahim Hamat Zeinabou Maiga Moussa Tondi Ahmed Tall lemrabott Maria Faye Cisse Mouhamadou Moustapha Kossi Akomola Sabi ka Elhaj Fary ka Niang Abdou Diouf Boucar Hemodialysis Unit H&#244pital Général de Référence Nationale (HGRN) N’Djamena Tchad Medical Department FSS/ Université Abdou Moumouni de Niamey Service de Néphrologie et Hémodialyse H&#244pital National Lamordé de Niamey Niamey Niger Nephrology service H&#244pital Aristide Le Dantec de Dakar Dakar Sénégal Nephrology and Hemodialysis Service CHU SO Lomé Lomé Togo

Introduction: Hyperuricemia is defined as a level of serum uric acid greater than or equal to 70 mg/l (420 μmol/l) in men and 60 mg/l (360 μmol/l) in women. Several studies have shown that it is a risk factor or a factor of progression of chronic kidney disease. Recent experimental and epidemiological data correlate the association of hyperuricemia with chronic kidney disease (CKD), arterial hypertension and cardiovascular diseases, thus raising the question of the usefulness of therapeutics in the prevention of renal diseases. The objective of this study is to seek a link between chronic kidney disease and hyperuricemia. Materials and Methods: This is a descriptive and analytical study conducted at hemodialysis unit and cardiology service of General Hospital of National reference of N’Djamena (Chad) from 1th January to 1th October 2013 (10 months). We included all chronic kidney disease patients hospitalized in hemodialysis unit and cardiology service who presented associated hyperuricemia. Results: There were 712 CKD patients who were hospitalized. Among them, there were 108 patients who were included in the study and who had hyperuricemia as a prevalence of 15.20%. The average age of patients was 35.5 years and the sex ratio was 3/1. The age group between 40 to 60 years represented 54.6%. There were 41.7% of traders. Hypertensive patients accounted for 49.1%;association of diabetes and hypertension was noted in 12.90%. Renal insufficiency was moderate in 43.5% of patients. Hyperuricemia was present in more than 90% of patients. Profession, age, hematuria, proteinuria and hypertension were statistically positively related to hyperuricemia. Treatment consisted of prescribing allopurinol in 84% of patients. In more than 11% of patients the progression was unfavorable. Conclusion: The implication of hyperuricemia in chronic kidney disease has been proved in several recent studies. However, randomized studies at very long scales have to be carried out to conclude from

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