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Focusing on caveolin-1 in CNS autoimmune disease:multiple sclerosis

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Neural Regeneration Research 2016年第12期11卷 1920-1921页

作者： Hao wu Jiangang Shen School of Chinese Medicine Li Ka Shing Faculty of MedicineThe University of Hong Kong

Multiple sclerosis（MS）is the leading autoimmune disorder in the central nervous system（CNS）that affects over 2.5 million people ***,the disease is characterized with severe neurological defects and motor disabilities such as paresis and *** autoimmune encephalomyelitis（EAE）is a well-defined laboratory animal model of MS that mimics key features of disease including aberrant auto-reactive immune activations in the periphery,

关键词： CNS EAE

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某铁尾矿“磁化焙烧-磁选”深度回收工艺

烧结球团 2024年第4期49卷 77-82页

作者：肖硕黄自力郑洁淼刘晓峰吴纪龙武汉科技大学资源与环境工程学院湖北武汉430081 武汉科技大学冶金矿产资源高效利用与造块湖北省重点实验室湖北武汉430081

针对某铁尾矿易泥化,夹带严重,常规磁选、浮选法回收铁品位不高的问题,本文采用强磁抛尾—磁化焙烧—弱磁粗选—细磨—弱磁精选的选矿工艺流程,探讨了强磁选磁场强度、焙烧配煤量、焙烧温度、焙烧时间、两段弱磁选磁场强度及磨矿细度等... 详细信息

针对某铁尾矿易泥化,夹带严重,常规磁选、浮选法回收铁品位不高的问题,本文采用强磁抛尾—磁化焙烧—弱磁粗选—细磨—弱磁精选的选矿工艺流程,探讨了强磁选磁场强度、焙烧配煤量、焙烧温度、焙烧时间、两段弱磁选磁场强度及磨矿细度等试验条件对选矿指标的影响。试验结果表明,最佳选矿条件:强磁选磁场强度为954.93 ka/m;焙烧配煤量为8%、焙烧温度为750℃、焙烧时间为20 min;弱磁粗选磁场强度为79.58 ka/m,粗选精矿磨矿细度ka/m。在这一条件下,经过磁化焙烧后,夹带现象明显减弱,最终可获得w(TFe)为61.55%的铁精矿。

关键词：铁尾矿赤铁矿磁化焙烧磁选

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高强钢激光熔透焊接接头残余应力数值分析

制造技术与机床 2024年第7期 55-62页

作者：吴若麟程开甲戴威严威李欢欢武汉工程大学机电工程学院湖北武汉430205 化工装备强化与本质安全湖北省重点实验室湖北武汉430205

为探究高强钢大功率激光单道熔透焊接接头中的残余应力及塑性应变分布规律,基于峰值指数递增双锥体热源模型对焊接接头进行热-弹-塑性有限元分析,发现采用该热源模型仿真计算的温度场与实际焊缝轮廓吻合较好,关键参数对比最大误差为-3.4... 详细信息

为探究高强钢大功率激光单道熔透焊接接头中的残余应力及塑性应变分布规律,基于峰值指数递增双锥体热源模型对焊接接头进行热-弹-塑性有限元分析,发现采用该热源模型仿真计算的温度场与实际焊缝轮廓吻合较好,关键参数对比最大误差为-3.45%;焊接接头残余应力沿着焊缝中心至两边呈对称分布,沿路径L2在起焊与止焊处的应力分布波动较大,这与节点温度历程曲线相一致;焊接接头在焊缝区发生了塑性应变,而远离焊缝区范围内未发生塑性应变。沿路径L1的焊缝区最大塑性应变峰值及峰值梯度均为等效塑性应变;沿路径L2在起焊及止焊处的纵向、横向及等效塑性应变波动幅值较大,且等效塑性应变峰值最高,横向塑性应变峰值梯度最大,它们的值分别为0.064及0.079。

关键词：高强钢大功率激光热弹塑性有限元残余应力塑性应变

试述促进中西医学沟通和结合的现代研究进展——以UCLA东西医学中心的结合医学模式为例

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中国中西医结合杂志 2019年第12期39卷 1500-1505页

作者：吴夏秋许家杰浙江中医药大学基础医学院、公共卫生学院杭州310053 美国加州大学洛杉矶分校(UCLA)东西医学中心美国90024

西方医学重新认识到人的"整体性"和"系统性",并提出"以患者为中心"的医疗模式;现代生物医学与中医学的研究理念逐渐开始融合,不断涌现的研究方法和成果为中西医结合提供了沟通桥梁。在"东西方医学结合,以患者为中心"模式下,加州大学洛... 详细信息

西方医学重新认识到人的"整体性"和"系统性",并提出"以患者为中心"的医疗模式;现代生物医学与中医学的研究理念逐渐开始融合,不断涌现的研究方法和成果为中西医结合提供了沟通桥梁。在"东西方医学结合,以患者为中心"模式下,加州大学洛杉矶分校(UCLA)东西医学中心(CEWM)将生物医学最新研究成果与现代中医研究充分融合,并以此指导教学、临床与科研工作。本文以心血管疾病、慢性疼痛为例,简要介绍CEWM的中西医结合医疗模式,以及支撑该模式的部分现代研究进展(应变稳态、韧性、筋膜系统),希望为中西医结合临床、科研、教育工作者提供思路。

关键词：结合医学以患者为中心应变稳态韧性筋膜系统

Improving hydrogen evolution performance of Co:FeS2/CoS2 nano-heterostructure at elevated temperatures

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Improving hydrogen evolution performance of Co:FeS2/CoS2 nan...

中国化学会第二十次全国电化学大会

作者： ka Wang Haizeng Song Zixia Lin Yuan Gao Han wu Shancheng Yan Jun Wang Yi Shi School of Geography and Biological Information Nanjing University of Posts and Telecommunications School of Electronic Science and Engineering Nanjing University Testing center Yangzhou University

In order to effectively alleviate global emergency energy and environmental problems, development of efficient and durable earth-abundant non-precious metal electrocatalysts for hydrogen evolution reaction（HER） is particularly important in the field of renewable energy[1]. Conventional electrocatalysts rely mainly on precious metals for hydrogen evolution at ambient temperatures, but high cost and scarcity severely hamper a wide range of applications[2]. Therefore, developing high-efficiency electrocatalysts with durability and low cost is imperative. Iron sulfide has been attracting attention for decades due to its low cost, richness and environmental compatibility. However, low surface area, lack of active sites and durability make iron sulfide rarely exhibit excellent HER performance[3]. Recently, both experimental and density functional theory（DFT） have concluded that the doping of homologous atoms and the formation of nano-heterostructure will greatly increase the number of active sites of iron sulfide and effectively reduce the energy barrier of reaction[4]. Dense radial nanostructures facilitate electron transport and rapid hydrogen release. In this study, we proposed a new type of Co:FeS2/CoS2 nano-heterostructure with excellent electrocatalytic properties by a simple hydrothermal method. Radial nano-heterostructures are densely distributed on carbon fiber paper, giving it a large specific surface area and more active sites. As a working electrode for HER, the nano-heterostructure exhibits a low overpotential of 90 mV at a current density of 10 mA cm-2 in a 0.5 M H2SO4 solution at 60℃, while the Tafel slope is only 63 mV dec-1. In addition, the HER overpotential increased by 6 mV after 1000 cycles CV in a 0.5 M H2SO4 solution at 60 ℃, showing significant electrochemical durability. This study provides a means to design high performance non-precious metal HER catalysts through a low cost and scalable approach.

关键词： Co:ZnS/CoS2 nano-heterostructure Electrocatalyst CarbonFiberPaper HydrogenEvolutionRecation

来源： cnki会议评论

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强激子-声子系统中电磁感应透明理论计算

量子光学学报 2006年第3期12卷 151-155页

作者：姚鸣朱卡的袁晓忠蒋逸文吴卓杰宁夏大学物理电气信息学院宁夏银川750001 上海交通大学物理系上海200030

应用Dyson-M aleev变换,对强耦合激子—声子系统中在考虑相空间填充因子情况下光的线性极化率进行了计算,在理论上证明了强激子-声子的相互作用对产生电磁感应透明起着重要作用,当信号光场频率与激子频率的失谐量等于光学声子的频率时,... 详细信息

应用Dyson-M aleev变换,对强耦合激子—声子系统中在考虑相空间填充因子情况下光的线性极化率进行了计算,在理论上证明了强激子-声子的相互作用对产生电磁感应透明起着重要作用,当信号光场频率与激子频率的失谐量等于光学声子的频率时,会出现电磁感应透明现象,并对考虑与不考虑相空间填充因子的两种情况作了比较,发现相空间填充因子对产生电磁感应透明现象没有实质的影响,只是使超慢光效应略有减弱。

关键词：量子光学电磁感应透明激子声子相空间填充因子

Design and Analysis of Novel ka Band NOMA Uplink Relay System for Lunar Farside Exploration

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中国通信：英文版 2020年第7期17卷 1-14页

作者： Jian Jiao Yizhi He Ye Wang Shaohua wu School of Electronic and Information Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Peng Cheng Laboratory Shenzhen 518055China

This paper proposes a novel ka band non-orthogonal multiple access(NOMA)uplink relay system for Lunar farside exploration,where a satellite relay node with the help of NOMA scheme,amplifies and forwards the signal from the Earth Base Station(EBS)to a Lunar rover and a *** assume that the signal undergoes shadowed-Rician fading for the source-relay link and Rayleigh fading for the relay-destination ***,the analytical expressions for the outage probability(OP)and ergodic capacity are derived for the satellite relay node equipped with single and multiple antennas,*** addition,we obtain the optimal power allocation coefficients by maximizing the sum ergodic capacity of the system,and we calculate the power consumption of the NOMA uplink relay system to achieve the same OP performance of OMA system and provide some useful guides for the design of the Earth-to-Lunar communication *** are provided to confirm the reliability of our analytical results and show the impact of various parameters on the system performance.

关键词： NOMA system Earth

Active learning accelerated Monte-Carlo simulation based on the modified K-nearest neighbors algorithm and its application to reliability estimations

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Defence Technology（防务技术） 2023年第10期28卷 306-313页

作者： Zhifeng Xu Jiyin Cao Gang Zhang Xuyong Chen Yushun wu School of Civil Engineering and Architecture Wuhan Institute of TechnologyWuhan430200PR China School of Mechanical and Electrical Engineering Wuhan Institute of TechnologyWuhan430200PR China Failure Mechanics&Engineering disaster Prevention and Mitigation Key Laboratory of Sichuan ProvinceSichuan UniversityChengdu610065PR China

This paper proposes an active learning accelerated Monte-Carlo simulation method based on the modified K-nearest neighbors *** core idea of the proposed method is to judge whether or not the output of a random input point can be postulated through a classifier implemented through the modified K-nearest neighbors *** to other active learning methods resorting to experimental designs,the proposed method is characterized by employing Monte-Carlo simulation for sampling inputs and saving a large portion of the actual evaluations of outputs through an accurate classification,which is applicable for most structural reliability estimation ***,the validity,efficiency,and accuracy of the proposed method are demonstrated *** addition,the optimal value of K that maximizes the computational efficiency is ***,the proposed method is applied to the reliability estimation of the carbon fiber reinforced silicon carbide composite specimens subjected to random displacements,which further validates its practicability.

关键词： Active learning Monte-carlo simulation K-nearest neighbors Reliability estimation Classification

龙川江流域近20年土壤侵蚀时空变化及驱动因素分析

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水土保持学报 2024年第4期38卷 29-37页

作者：彭大力张斌吴林蓬邹介石罗君刘辉王磊西华师范大学地理科学学院四川南充637009 西华师范大学四川省干旱河谷土壤侵蚀监测与控制工程实验室四川南充637009 大小凉山干旱河谷土壤侵蚀与生态修复野外科学观测研究站四川喜德616753

[目的]探究龙川江流域土壤侵蚀时空变化及其主控因子并掌握当地水土保持情况,有利于筑牢长江上游生态屏障。[方法]采用通用土壤流失方程RUSLE,结合GIS和RS技术,研究龙川江流域2000—2020年的土壤侵蚀时空变化特征,同时利用最优参数地理... 详细信息

[目的]探究龙川江流域土壤侵蚀时空变化及其主控因子并掌握当地水土保持情况,有利于筑牢长江上游生态屏障。[方法]采用通用土壤流失方程RUSLE,结合GIS和RS技术,研究龙川江流域2000—2020年的土壤侵蚀时空变化特征,同时利用最优参数地理探测器(OPGD)模型,量化驱动因子对龙川江流域土壤侵蚀时空动态变化的影响力和相互作用。[结果](1)龙川江流域土壤侵蚀主要以微度和中度侵蚀为主,面积占比分别为2000年49.17%,2010年50.29%,2020年59.29%。2000—2010年土壤侵蚀变化较小,2010—2020年,共有9.01%的中度及以上侵蚀区域转为微度和轻度侵蚀。(2)最优参数地理探测器结果显示,在选取的影响因子中土地利用类型对研究区土壤侵蚀时空动态变化解释力最强,q值为0.18。土地利用类型与坡度的交互作用对龙川江流域土壤侵蚀解释力最强,q值达到0.45。[结论]龙川江流域的土壤侵蚀主要以微度和轻度侵蚀为主,整体呈好转趋势,但元谋盆地土壤侵蚀仍较剧烈。土地利用类型对流域内土壤侵蚀的影响最强,而研究区最主要的土地利用类型为植被,占总面积的67.02%,因此未来需重点关注植被覆盖区域变化,继续推进生态保护政策,警惕地形复杂区域水土流失加剧风险。

关键词：土壤侵蚀 RUSLE模型最优参数地理探测器植被覆盖龙川江流域