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Testicular sperm extraction(TESE)outcomes in the context of malignant disease:a systematic review

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Asian Journal of Andrology 2022年第6期24卷 584-590页

作者： Ludmilla Ogouma Isabelle Berthaut Rachel Lévy Rahaf Haj Hamid marie Prades marie Audouin Nathalie Sermondade Charlotte Dupont Fertility Center(Service de Biologie de la Reproduction CECOS) Tenon Hospital(AP-HPSorbonne-Universite)Paris F-75020France Sorbonne University Saint Antoine Research CenterInserm Us938Paris F-75012France Fertility Center Diaconesses HospitalParis F-75012France

Advances in the oncology field have led to improved survival ***,quality of life after remission is anticipated,which includes the possibility to conceive *** cancer treatments are potentially gonadotoxic,fertility preservation must be *** fertility preservation is mainly based on ejaculated sperm *** this is not possible,testicular sperm extraction(TESE)may be *** identify situations in which TESE has been beneficial,a systematic review was *** search was carried out on the PubMed,Scopus,Google Scholar,and CISMeF databases from 1 January 2000 to 19 March *** Reporting Items for Systematic Reviews and Meta-Analyses(PRISMA)recommendations were followed in selecting items of ***-four articles were included in the systematic review,including 15 articles on oncological testicular sperm extraction(oncoTESE),18 articles on postgonadotoxic treatment TESE and 1 article on both oncoTESE and postgonadotoxic treatment *** sperm freezing was possible for 42.9%to 57.7%of patients before gonadotoxic treatment and for 32.4%to 75.5%of patients after gonadotoxic treatment,depending on the type of malignant *** no formal conclusion could be drawn about the chances to obtain sperm in specific situations,our results suggest that TESE can be proposed before and after gonadotoxic *** treatment,TESE is more often proposed for men with testicular cancer presenting with azoospermia since TESE can be performed simultaneously with tumor removal or *** chemotherapy,TESE may be planned if the patient presents with persistent azoospermia.

关键词： cancer fertility preservation oncological testicular sperm extraction spermatozoa testicular sperm extraction

Improved outcome with standardized plan for clinical management of acute decompensated chronic heart failure

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Journal of Geriatric Cardiology 2019年第1期16卷 12-18页

作者： marie-Louise Edvinsson Albin Stenberg karin Astrom-Olsson Department of Emergency and Internal Medicine University'Hospital of LundSweden Institute of Clinical Sciences L und UniversityL undSweden Department of Cardiology University>Hospital of MalmoSweden

Background Our overall goal is to improve clinical care for inpatients with chronic heart failure(CHF).A retrospective assessment of CHF patients admitted to our hospital over the past decade(2005 vs.2014)indicated a need for better strategies to evaluate clinical treatment,implement best practices and achieve optimal patient *** that purpose,we developed a standardized plan to improve in-hospital treatment of acute decompensated CHF ***&Results Retrospective chart reviews were conducted to compare three cohorts of CHF patients admitted to the University Hospital of Lund at different time points over a 12-year period:2005(365 patients),2014(172 patients)and 2017-2018(57 patients).Little improvement was seen between 2005 and 2014 with respect to one-year mortality(35%vs.34%)and adequate treatment with recommended medications,e.g.,use of renin-angiotensin system blockers(45%vs.51%).A standardized treatment plan was devised to improve outcomes.A third cohort,treated under the plan(2017-2018),was compared with the 2014 ***-year mortality(18%vs.34%)and 30-day readmission(5%vs.30%)were dramatically decreased,and adherence to medication guidelines was *** elements of the plan included well-defined treatment procedures,enhanced communication and teamwork,education,adequate time for treatment(5 days)and post-discharge follow-up as *** peptide(NT-proBNP)levels were useful for assessing patient status,prognosis and response to *** Developmeof a standard plan for clinical management of acute decompensated CHF patients resulted in significant improvements in patient outcome,as reflected in decreased rates of 30-day readmission and one-year mortality.

关键词： Chronic heart failure Medication NT-proBNP Prognosis

Respiratory supercomplexes:structure,function and assembly

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Protein & Cell 2013年第8期4卷 582-590页

作者： Rasika Vartak Christina Ann-marie Porras Yidong Bai Department of Cellular and Structural Biology University of Texas Health Science Center at San AntonioSan AntonioTX 78229USA

The mitochondrial respiratory chain consists of 5 enzyme complexes that are responsible for ATP *** paradigm of the electron transport chain as discrete enzymes diffused in the inner mitochondrial membrane has been replaced by the solid state supercomplex model wherein the respiratory complexes associate with each other to form supramolecular *** in these supercomplexes,which have been shown to be functionally active and required for forming stable respiratory complexes,have been associated with many genetic and neurodegenerative disorders demonstrating their biomedical signifi *** this review,we will summarize the functional and structural signifi cance of supercomplexes and provide a comprehensive review of their assembly and the assembly factors currently known to play a role in this process.

关键词： supercomplex mitochondrial respiration

Safe acupuncture and dry needling during pregnancy:New Zealand physiotherapists' opinion and practice

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Journal of Integrative Medicine 2019年第1期17卷 30-37页

作者： Jillian marie McDowell Susan Heather Kohut Debra Betts Prohealth Physiotherapy School of Clinical Sciences Faculty of Health and Environmental Sciences Auckland University of Technology New Zealand School of Acupuncture and Traditional Chinese Medicine

Objective: Acupuncture guidelines have advised caution when treating women during pregnancy,because historical ‘‘forbidden" acupuncture points are believed to stimulate miscarriage or early *** recent research demonstrating that acupuncture is a useful and safe treatment tool for pregnancy-related low-back pain(LBP) and pelvic girdle pain(PGP), it is postulated that fear of miscarriage and subsequent blame by association, restricts its provision. More recently, an increase in dry needling(DN) courses for physiotherapists has potentiated the rapid growth in DN practice in New Zealand(NZ). Many dry needlers do not consider DN to be a form of acupuncture; it is unknown if they have similar safety ***: NZ registered physiotherapists practicing acupuncture and/or DN were invited to participate in an electronic survey to examine their practice and level of understanding in regard to safe needling during ***: Of 124 respondents, only 60(48%) would needle pregnant women, with a further 66% of those still expressing safety concerns. NZ physiotherapists practicing DN only, were more likely to needle areas related to ‘‘forbidden" points in all trimesters. However, overall, NZ physiotherapists were less likely to needle ‘‘forbidden" points than their UK ***: Conflicting literature and a ‘‘fear of blame" influences NZ physiotherapists' decisions to offer needling(both acupuncture and DN) during pregnancy. Further training in this field is recommended to ensure safe practice and adequate provision of acupuncture treatment options for pregnant women suffering musculoskeletal pain, such as LBP and PGP. Further research, particularly into DN, for women during pregnancy, is warranted.

关键词： Physiotherapy Acupuncture Dry needling Safety Pregnancy Trigger point therapy

Gender-specific associations between coronary heart disease and other chronic diseases: cross-sectional evaluation of national survey data from adult residents of Germany

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Journal of Geriatric Cardiology 2019年第9期16卷 663-670,I0002-I0005页

作者： marie-Isabel K Murray Kerstin Bode Peter Whittaker Department of Cardiology University Hospital Frankfurt am Main Frankfurt Germany Department of Electrophysiology Heart Center Leipzig Leipzig Germany Cardiovascular Research Institute and Department of Emergency Medicine Wayne State University Detroit MI USA

Background Combinations of coronary heart disease(CHD) and other chronic conditions complicate clinical management and increase healthcare costs. The aim of this study was to evaluate gender-specific relationships between CHD and other comorbidities. Methods We analyzed data from the German Health Interview and Examination Survey(DEGS1), a national survey of 8152 adults aged 18-79 years. Female and male participants with self-reported CHD were compared for 23 chronic medical conditions. Regression models were applied to determine potential associations between CHD and these 23 conditions. Results The prevalence of CHD was 9%(547 participants): 34%(185) were female CHD participants and 66%(362) male. In women, CHD was associated with hypertension(OR = 3.28(1.81-5.9)), lipid disorders(OR = 2.40(1.50-3.83)), diabetes mellitus(OR = 2.08(1.24-3.50)), kidney disease(OR = 2.66(1.101-6.99)), thyroid disease(OR = 1.81(1.18-2.79)), gout/high uric acid levels(OR = 2.08(1.22-3.56)) and osteoporosis(OR = 1.69(1.01-2.84)). In men, CHD patients were more likely to have hypertension(OR = 2.80(1.94-4.04)), diabetes mellitus(OR = 1.87(1.29-2.71)), lipid disorder(OR = 1.82(1.34-2.47)), and chronic kidney disease(OR = 3.28(1.81-5.9)). Conclusion Our analysis revealed two sets of chronic conditions associated with CHD. The first set occurred in both women and men, and comprised known risk factors: hypertension, lipid disorders, kidney disease, and diabetes mellitus. The second set appeared unique to women: thyroid disease, osteoporosis, and gout/high uric acid. Identification of shared and unique gender-related associations between CHD and other conditions provides potential to tailor screening, preventive, and therapeutic options.

关键词： Chronic diseases Comorbidities Gender Heart disease Risk factors Survey data

The Wiseman and the Sage： Metaphysics as Wisdom in Aristotle and the Neo-Confucian School of Pdnciple

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Frontiers of Philosophy in China 2013年第1期8卷 120-139页

作者： Rina marie Camus Department of Philosophy National Chengehi University Taipei 11605 China

Among scholars of classical philosophy in the West, it is not uncommon to hesitate about the existence of metaphysics in non-Western philosophical traditions. At times, the dilemma seems due to culture-specific ideas or standards about what metaphysics is or how it should be done. Other times the problem seems to lie in a general lack of awareness about the methods and approaches of divergent philosophical traditions. This article explores an often ignored Aristotelian notion of metaphysics： That it is wisdom. If we acknowledge wisdom to be a common value or ideal found in different cultures, then characterizing metaphysics as wisdom promises to be more inclusive than prevalent ideas about it, being broad enough to allow for the appreciation of metaphysical insights and achievements in non-Western schools. I first examine Aristotle＇s account of what wisdom consists of. I shall then test the inclusivity of this conception of metaphysics by showing how its characteristic features are manifest in the Neo-Confucian ideal of sagely learning.

关键词： metaphysics wisdom principle theory Aristotle Neo-ConfucianSchool of Principle

“Athl-Ethics”:Virtue Training in Mencius and Aristotle

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Frontiers of Philosophy in China 2019年第1期14卷 152-170页

作者： Rina marie Camus General Education Centre The Hong Kong Polytechnic University Hong Kong China

The late Zhou of China and the Classical age of Greece both saw great impetus in intellectual thought and were marked by intense warfare. Being closely linked to warfare in antiquity, sports was a vital, commonplace activity whose jargon and practices naturally informed philosophical discourses. One can thus observe convergences between athletics and ethics in texts which took shape in these times and places, a phenomenon which I shall refer to as "athl-ethics." In this paper, I separately examine and then compare athl-ethic phenomenon in Mencius and in the Nicomachean Ethics. Both texts are rife with sports metaphors. I regard the use of sports-derived imagery as a thin form of athl-ethicism. Sports, however, did more than inspire useful analogies. Physical training and competition were considered occasions for nourishing and practicing virtue. This generated thicker forms of athl-ethicism.

关键词： athl-ethics sports moral philosophy Mencius Aristotle

From Yokohama to Sendai: Approaches to Participation in International Disaster Risk Reduction Frameworks

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International Journal of Disaster Risk Science 2015年第2期6卷 128-139页

作者： Arielle Tozier de la Poterie marie-Ange Baudoin Consortium for Capacity Building Institute of Arctic and Alpine Research (INSTAAR) University of Colorado Researcher & Course Convener African Climate & Development Initiative (ACDI) University of Cape Town

Taking the importance of local action as a starting point, this analysis traces the treatment of participation of local and community actors through the three international frameworks for disaster risk reduction(DRR): the Yokohama Strategy and Plan of Action for a Safer World, the Hyogo Framework for Action 2005–2015, and the Sendai Framework for Disaster Risk Reduction 2015–2030(SFDRR). The study finds a concerning shift away from valuing local community input and toward promoting technological advances. Community actors went from valued partners with their own expertise and relevant beliefs in Yokohama Strategy to ‘‘aid recipients’ ’ to whom tailored risk information must be transmitted(in SFDRR). This shift may reflect the top-down nature of negotiated international agreements or a broader shift toward investments in technological solutions. Whatever the cause, given widespread recognition of the importance of local knowledge and participation and growing recognition of the importance of intra-community differences in vulnerability, it suggests the need for reconsideration of both the discourse and the practice of involving community-level actors in DRR planning and implementation.

关键词： Community participation Disaster risk reduction Discourse analysis International frameworks

Do the microorganisms from laboratory culture spent growth medium affect house dust mite fitness and microbiome composition?

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Insect Science 2020年第2期27卷 266-275页

作者： Vit Molva marie Bostlova Marta Nesvorna Jan Hubert Crop Research Institute Prague 6-RuzyneCzechia Faculty of Science Department of ParasitologyCharles UniversityPrague 2Czechia

The interaction of house dust mites(HDM)and microorganisms is the key factor in the survival of these mites in human-made *** growth medium(SPGM)provides the rest of the dict,along with dead mite bodies and *** represents a source of microorganisms for the recolonization of mite food and the mite digestive *** experiment was performed to observe how adding SPGM to the HDM diet affects HDM population growth,the microbiome composition and the microbial respiration in *** analyzed American house dust mite(Dermatophagoides farinae)and European house dust mite(Dermatophagoides pleronyssinus)originating from control diets and diets treated with an extract of SPGM from 1-and 3-month-old mite *** microbiome was described using 16S and 18S barcode *** composition of the bacterial and fiungal microbiomes differed between the HDM species,but the SPGM treatment influenced only the bacterial profile of *** the *** microbiome of specimens on SPGM-treated dicts compared to those of the control situation,the Lactobacillus profile decreased,while the Candinium,Staphylococ-cus,Acinetobacter,and Sphingomonas profiles *** addition of SPGM extract decreased the microbial respiration in the microcosms with and without mites in almost all *** SPGM did not influence the population growth of ***,but it had a variable effect on *** results indicated that the HDM are marginally influenced by the microorganisms in their feces.

关键词： diet feces feeding house dust mites microbiome microorganisms mites