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Acute phase reaction and acute phase proteins

journal of Zhejiang University-science B(Biomedicine & Biotechnology) 2005年第11期6卷 1045-1056页

作者： GRUYs E. TOUssAINT M.j.M. NIEWOLD T.A. koopmans s.j. Department of Pathobiology Faculty of Veterinary Medicine Utrecht University Utrecht the NetherlandsDepartment of Pathobiology Faculty of Veterinary Medicine Utrecht University Utrecht the NetherlandsAnimal Sciences Group Wageningen University Research Lelystad the NetherlandsAnimal Sciences Group Wageningen University Research Lelystad the Netherlands

A review of the systemic acute phase reaction with major cytokines involved, and the hepatic metabolic changes, negative and positive acute phase proteins (APPs) with function and associated pathology is given. It appears that APPs represent appropriate analytes for assessment of animal health. Whereas they represent non-specific markers as biological effect reactants, they can be used for assessing nutritional deficits and reactive processes, especially when positive and negative acute phase variables are combined in an index. When such acute phase index is applied to separate healthy animals from animals with some disease, much better results are obtained than with single analytes and statistically acceptable results for culling individual animals may be reached. Unfortunately at present no cheap, comprehensive and easy to use system is available for assessing various acute phase proteins in serum or blood samples at the same time. Protein microarray or fluid phase microchip technology may satisfy this need; and permit simultaneous analysis of numerous analytes in the same small volume sample and enable integration of information derived from systemic reactivity and nutrition with disease specific variables. Applying such technology may help to solve health problems in various countries not only in animal husbandry but also in human populations.

关键词： Acute phase protein Acute phase reaction Animal health Assessment Cytokine Index Nutrition

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Women in visual neural regeneration research

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Neural Regeneration Research 2025年第2期20卷 489-490页

作者： Tonia s.Rex David j.Calkins Vanderbilt Eye Institute Vanderbilt University Medical CenterNashvilleTNUSA

The year 2024 marks the 60^(th)anniversary of Title IX and 25 years since the New York Times revealed bias against female faculty members at the Massachusetts Institute of *** take an opportunity here to examine the state of gender bias in a relatively new yet already prominent field,neural regeneration in the visual system,for which there is a well-defined context useful for this *** National Eye Institute(NEI)provided the first round of research funding for its Audacious Goals Initiative(AGI)on visual neural regeneration in 2013 and the last round in ***,we focus on this *** sources included PubMed,the National science Foundation(NsF),the NEI,the Blue Ridge Institute for Medical Research and data from the major professional organization for eye and vision research,the Association for Research in Vision and Ophthalmology(ARVO).

关键词： neural visual Times

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Combinatorial therapies for spinal cord injury repair

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Neural Regeneration Research 2025年第5期20卷 1293-1308页

作者： Carla s.sousa Andreia Monteiro António j.salgado Nuno A.silva Life and Health sciences Research Institute(ICVs) School of MedicineUniversity of MinhoCampus de Gualtar-gualtarBragaPortugal ICVs/3B’s Associate Lab PT Government Associated LabCampus de Gualtar-gualtarBragaPortugal

spinal cord injuries have profound detrimental effects on individuals, regardless of whether they are caused by trauma or non-traumatic events. The compromised regeneration of the spinal cord is primarily attributed to damaged neurons, inhibitory molecules, dysfunctional immune response, and glial scarring. Unfortunately, currently, there are no effective treatments available that can fully repair the spinal cord and improve functional outcomes. Nevertheless, numerous pre-clinical approaches have been studied for spinal cord injury recovery, including using biomaterials, cells, drugs, or technological-based strategies. Combinatorial treatments, which target various aspects of spinal cord injury pathophysiology, have been extensively tested in the last decade. These approaches aim to synergistically enhance repair processes by addressing various obstacles faced during spinal cord regeneration. Thus, this review intends to provide scientists and clinicians with an overview of pre-clinical combinatorial approaches that have been developed toward the solution of spinal cord regeneration as well as update the current knowledge about spinal cord injury pathophysiology with an emphasis on the current clinical management.

关键词： electric stimulation neural tissue regeneration neuroprotection polytherapy spinal cord injury

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Mitigating Hotspot Problem Using Northern Goshawk Optimization Based Energy Aware Multi-Hop Communication for Wireless sensor Networks

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China Communications 2025年第2期22卷 283-298页

作者： s.Leones sherwin Vimalraj j.Lydia Department of Electronics and Communication Engineering Panimalar Engineering CollegeChennai 600123India Department of Electrical and Electronics Engineering Easwari Engineering CollegeChennai 600089India

Wireless sensor Network(WsN)comprises a set of interconnected,compact,autonomous,and resource-constrained sensor nodes that are wirelessly linked to monitor and gather data from the physical *** are commonly used in various applications such as environmental monitoring,surveillance,healthcare,agriculture,and industrial *** the benefits of WsN,energy efficiency remains a challenging problem that needs to be *** and routing can be considered effective solutions to accomplish energy efficiency in *** studies have reported that metaheuristic algorithms can be applied to optimize cluster formation and routing *** study introduces a new Northern Goshawk Optimization with boosted coati optimization algorithm for cluster-based routing(NGOBCO-CBR)method for *** proposed NGOBCO-CBR method resolves the hot spot problem,uneven load balancing,and energy consumption in *** NGOBCO-CBR technique comprises two major processes such as NGO based clustering and BCO-based *** the initial phase,the NGObased clustering method is designed for cluster head(CH)selection and cluster construction using five input variables such as residual energy(RE),node proximity,load balancing,network average energy,and distance to Bs(DBs).Besides,the NGOBCO-CBR technique applies the BCO algorithm for the optimum selection of routes to *** experimental results of the NGOBCOCBR technique are studied under different scenarios,and the obtained results showcased the improved efficiency of the NGOBCO-CBR technique over recent approaches in terms of different measures.

关键词： clustering energy efficiency metaheuristics multihop communication network lifetime wireless sensor networks

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INTRODUCTION TO INCONEL ALLOY 740: AN ALLOY DEsIGNED FOR sUPERHEATER TUBING IN COAL-FIRED ULTRA sUPERCRITICAL BOILERs

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Acta Metallurgica sinica(English Letters) 2005年第4期18卷 479-488页

作者： s.j. Patel special Metals Corporation Huntington WV 25705 USA

Chinese utilities as well as those worldwide are facing increased demand for additional electricity, reduced plant emissions and greater efficiency. To meet this challenge will require increasing boiler temperature, pressure and coal ash corrosion resistance of the materials of boiler construction of future coal-fired boilers. A new nickel-based tube alloy, INCONEL^R alloy 740, is described aiming at meeting this challenge. Emphasis will be on describing the alloy＇ s mechanical properties, coal-ash and steam corrosion resistance. Microstructural stability as a function of temperature and time is addressed as well as some of the early methodology em- ployed to arrive at the current chemical composition.

关键词： ultrasupercritical boiler tubing INCONEL coal-fired

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Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

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Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William j.Flerlage Mark L.Dell’Acqua Brian M.Cox Fereshteh s.Nugent Uniformed services University of the Health sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

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Analysis of convective-radiative heat transfer in dovetail longitudinal fins with shape-dependent hybrid nanofluids: a study using the Hermite wavelet method

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Applied Mathematics and Mechanics(English Edition) 2025年第2期46卷 357-372页

作者： C.G.PAVITHRA B.j.GIREEsHA s.sUsHMA K.j.GOWTHAM Department of PG studies and Research in Mathematics Kuvempu University

A distinguished category of operational fluids, known as hybrid nanofluids,occupies a prominent role among various fluid types owing to its superior heat transfer properties. By employing a dovetail fin profile, this work investigates the thermal reaction of a dynamic fin system to a hybrid nanofluid with shape-based properties, flowing uniformly at a velocity U. The analysis focuses on four distinct types of nanoparticles,i.e., Al2O3, Ag, carbon nanotube (CNT), and graphene. specifically, two of these particles exhibit a spherical shape, one possesses a cylindrical form, and the final type adopts a platelet morphology. The investigation delves into the pairing of these *** examination employs a combined approach to assess the constructional and thermal exchange characteristics of the hybrid nanofluid. The fin design, under the specified circumstances, gives rise to the derivation of a differential equation. The given equation is then transformed into a dimensionless form. Notably, the Hermite wavelet method is introduced for the first time to address the challenge posed by a moving fin submerged in a hybrid nanofluid with shape-dependent features. To validate the credibility of this research, the results obtained in this study are systematically compared with the numerical simulations. The examination discloses that the highest heat flux is achieved when combining nanoparticles with spherical and platelet shapes.

关键词： Hermite wavelet method radiation convection dovetail fin nanoparticle configuration O351.2

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solution of shallow-water equations using least-squares finite-element method

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Acta Mechanica sinica 2008年第5期24卷 523-532页

作者： s.j. Liang j,-H, Tang M.-s. Wu Department of Marine Environmental Informatics National Taiwan Ocean UniversityKeelung 20224 Taiwan China Department of Bioenvironmental Engineering Chung-Yuan Christian University Chung-Li 32023 Taiwan China Department of Geographic Information systems Feng Chia University Taichung 40724 Taiwan China

A least-squares finite-element method （LsFEM） for the non-conservative shallow-water equations is presented. The model is capable of handling complex topography, steady and unsteady flows, subcritical and supercritical flows, and flows with smooth and sharp gradient changes. Advantages of the model include：（1） sources terms, such as the bottom slope, surface stresses and bed frictions, can be treated easily without any special treatment; （2） upwind scheme is no needed; （3） a single approximating space can be used for all variables, and its choice of approximating space is not subject to the Ladyzhenskaya-Babuska-Brezzi （LBB） condition; and （4） the resulting system of equations is symmetric and positive-definite （sPD） which can be solved efficiently with the preconditioned conjugate gradient method. The model is verified with flow over a bump, tide induced flow, and dam-break. Computed results are compared with analytic solutions or other numerical results, and show the model is conservative and accurate. The model is then used to simulate flow past a circular cylinder. Important flow charac-teristics, such as variation of water surface around the cylinder and vortex shedding behind the cylinder are investigated. Computed results compare well with experiment data and other numerical results.

关键词： Least-square finite-element method,shallow-water equations Dam-break Vortex shedding

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Error resilient concurrent video streaming over wireless mesh networks

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journal of Zhejiang University-science A(Applied Physics & Engineering) 2006年第5期7卷 684-695页

作者： CHUAH Chen-nee YOO Ben s.j. Electrical and Computer Engineering Department University of California Davis 95616 USA Electrical and Computer Engineering Department

In this paper, we propose a multi-source multi-path video streaming system for supporting high quality concurrent video-on-demand (VoD) services over wireless mesh networks (WMNs), and leverage forward error correction to enhance the error resilience of the system. By taking wireless interference into consideration, we present a more realistic networking model to capture the characteristics of WMNs and then design a route selection scheme using a joint rate/interference-distortion optimiza- tion framework to help the system optimally select concurrent streaming paths. We mathematically formulate such a route selec- tion problem, and solve it heuristically using genetic algorithm. simulation results demonstrate the effectiveness of our proposed scheme.

关键词： Wireless mesh network, Concurrent video streaming, Interference

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La3+ substitution-adjusted magnetic and optical properties with enhanced photocatalytic activity and stability of copper zinc nickel ferrites for wastewater treatment applications

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journal of Rare Earths 2025年第2期43卷 319-328页

作者： N.s.Al-Bassami General studies Department Jubail Industrial College

Copper-zinc-nickel（Cu-Zn-Ni） ferrite nanoparticles are used for wastewater treatment ***,low degradation efficiency and stability are two main issues that make them unsuitable for actual production *** this paper,the citrate-nitrate auto-combustion method was applied for the formation of Cu0.5Zn0.25Ni0.25LaxFe2-xO4;（0≤x≤0.1;step 0.02）(CZNL) *** the substitution process entails the replacement of a small ion with a larger one,the lattice constant and crystallite size does not exhibit a consistent incremental *** behavior is.j.stified and *** size of all the CZNL ferrite nanoparticles is in the range of 8-12 nm,and the lattice constant is in the range of 8.6230 to 8.4865 *** morphological analysis conducted using field emission-scanning electron microscopy（FE-sEM） reveals that the CZNL exhibits agglomerated spherical *** energy dispersive X-ray spectrameter（EDAX） analysis was employed to confirm the elemental composition of CZNL *** the process entails the substitution of Fe3+magnetic ions with nonmagnetic ions La3+,the magnetic parameters of CZNL nanoferrites show a general decreasing trend as *** 20 K,saturation magnetization Ms shows an overall drop in its values from 59.302 emu/g at x=0.0-41.295 emu/g at x=0.1,the smallest value of 37.87 emu/g is recorded at x=*** highest coercivity（Hc=125.9 Oe） and remanence（Mr=13.32 emu/g） are recorded for x=0.08 and x=0.04 nanoferrite,*** band gap of all the CZNL nanoferrites was determined using the Kubelka-Munk function and Tauc plot for direct permitted *** doping modifies the band gap（within 1.86-1.75 eV）,increases light absorption,induces efficient e/h separation and charge migration to *** nanoferrite Cu0.5Zn0.25Ni0.25La0.06Fe1.94O4achieves a degradation efficiency of 97.3% for methylene blue（MB） dye removal after just 60 *** five recycling processes,the nanoc

关键词： Copper-zinc-nickel Ferrite Photocatalytic properties Rare earths Wastewater treatment

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