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Notably Accelerated Nano-Bainite Transformation via Increasing Undissolved Carbides Content on GCr15Si1Mo Bearing Steel

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Acta Metallurgica Sinica(English Letters) 2024年第4期37卷 703-712页

作者： Yan-Hui Wang hua-Qiang Sun Wen-Jing Feng Lei-Jie Zhao xiang Chen Qing-An Chen Hai-Tao Sun Jian-Jun Wang Zhi-Nan Yang Key Laboratory of Intelligent Industrial Equipment Technology of Hebei Province School of Mechanical and Equipment EngineeringHebei University of EngineeringHandan056038China Collaborative Innovation Center for Modern Equipment Manufacturing of Jinan New Area Hebei University of EngineeringHandan056038China School of Materials Science and Engineering Tsinghua UniversityBeijing100084China Avic Shang da Superalloys Company Limited Xingtai054800China National Engineering Research Center for Equipment and Technology of Cold Strip Rolling Yanshan UniversityQinhuangdao066004China

In this study, a high-carbon nano-bainitic GCr15Si1Mo bearing steel was investigated. Specifically, the effects of content and size of undissolved carbides on the microstructure and transformation kinetics of nano-bainite were analyzed. The results demonstrated that after prolonged austempering at low temperatures, the mixed microstructure composed of nano-bainite (NB), undissolved carbides (UC), and retained austenite (RA) was obtained in GCr15SiMo steel. When the experimental steel was austenitized at 900 ℃, the undissolved carbides gradually dissolved until reaching a stable state with increasing holding time. Furthermore, at the same austempering temperature, despite different volume fractions of undissolved carbides in the substrate, the volume fractions of nano-bainite in the final microstructures remained essentially the same. Moreover, the higher the content of undissolved carbides in steel, the faster the transformation rate of nano-bainite and the shorter the total transformation time.

关键词： Nano-bainite Undissolved carbides Bainitic transformation kinetics Carbon concentration

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Biological Evaluation of Lysionotin:a Novel Inhibitor of 5-Lipoxygenase for Anti-glioma

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Chinese Journal of Integrative Medicine 2024年第9期30卷 826-834页

作者： SHAO Xin-xin CHEN Cong LIU Jie LI Qing-jun HE Shan QI xiang-hua FU Xian-jun WANG Zhen-guo The First Clinical College of Medicine Shandong University of Traditional Chinese MedicineJinan250355China Institute for Literature and Culture of Chinese Medicine Shandong University of Traditional Chinese MedicineJinan250355China Key Laboratory of Classical Theory of Traditional Chinese Medicine Ministry of EducationShandong University of Traditional Chinese MedicineJinan250355China College of Pharmacy Shandong University of Traditional Chinese MedicineJinan250355China Experimental Center Shandong University of Traditional Chinese MedicineJinan250355China Neurology Department Affiliated Hospital of Shandong University of Traditional Chinese MedicineJinan250014China Marine Traditional Chinese Medicine Research Center Qingdao Academy of Traditional Chinese MedicineShandong University of Traditional Chinese MedicineQingdao266114Shandong ProvinceChina

Objective:To explore the potential mechanism of lysionotin in treating ***:First,target prediction based on Bernoulli Naïve Bayes profiling and pathway enrichment was used to predict the biological activity of *** binding between 5-lipoxygenase(5-LO)and lysionotin was detected by surface plasmon resonance(SPR)and molecular docking,and the inhibitory effects of lysionotin on 5-LO and proliferation of glioma were determined using enzyme inhibition assay in vitro and cell viability analysis,***,the pharmaceutical effect of lysionotin was explored by cell survival rate analysis and liquid chromatography with tandem mass spectrometry(LC-MS/MS).The protein expression,intracellular calcium ion concentration and cytoskeleton detection were revealed by Western blot,flow cytometry and fluorescence labeling,***:Target prediction and pathway enrichment revealed that lysionotin inhibited 5-LO,a key enzyme involved in the arachidonic acid metabolism pathway,to inhibit the proliferation of *** docking results demonstrated that 5-LO can be binding to lysionotin through hydrogen bonds,forming bonds with His600,Gln557,Asn554,and *** analysis further confirmed the interaction between 5-LO and ***,enzyme inhibition assay in vitro and cell survival rate analysis revealed that 50%inhibition concentration of lysionotin and the median effective concentration of lysionotin were 90 and 16.58µmol/L,respectively,and the results of LC-MS/MS showed that lysionotin inhibited the production of 5S-hydroperoxy-eicosatetraenoic acid(P<0.05),and moreover,the LC-MS/MS results indicated that lysionotin can enter glioma cells well(P<0.01)and inhibit their *** blot analysis demonstrated that lysionotin can inhibit the expression of 5-LO(P<0.05)and downstream leukotriene B4 receptor(P<0.01).In addition,the results showed that lysionotin affected intracellular calcium ion concentration by inh

关键词： 5-lipoxygenase inhibitor lysionotin 5-lipoxygenase leukotriene B4 calcium ion cytoskeleton

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浅谈舞蹈教学对学生感受力和表现力的培养

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湖南科技学院学报 2006年第7期27卷 280-281页

作者：孔湘华永州职院师范学院艺术系湖南永州425006

舞蹈的感受力和表现力,是通过对学生外部形态动作和内部情态的培养而派生出来的。因此,要培养学生的舞蹈感受力和表现力,就必须注意对学生外部形态动作和内部情态的双重培养。

关键词：舞蹈教学感受力表现力

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关于计算机技术在课堂教学中应用的思考

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佳木斯大学社会科学学报 2005年第4期23卷 111-112页

作者：孔祥华黑龙江建筑职业技术学院黑龙江哈尔滨150008

数学是集严密性、逻辑性、精确性和创造性与想象力于一身的科学,数学教学则要求学生在教师设计的教学活动或提供的环境中通过积极的思维不断了解、理解和掌握这门科学,于是揭示思维过程、促进学生思考就成为数学教育的特殊要求。计算机... 详细信息

数学是集严密性、逻辑性、精确性和创造性与想象力于一身的科学,数学教学则要求学生在教师设计的教学活动或提供的环境中通过积极的思维不断了解、理解和掌握这门科学,于是揭示思维过程、促进学生思考就成为数学教育的特殊要求。计算机是信息处理的有效工具,学科教学的经验使计算机技术在数学教学中发挥了特殊的功能。

关键词：数学教学计算机技术课堂教学

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汽车尾气三元催化转化器的数值模拟

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科学技术与工程 2011年第5期11卷 1018-1021页

作者：孔祥华宝鸡文理学院灾害监测与机理模拟陕西省重点实验室宝鸡721013

针对三元催化转化器的起燃特性,建立转化器的数学模型。给出化学反应速率方程和传热传质系数。讨论了在起燃阶段转化器内温度的分布和污染物质的转化情况。对催化转化器的优化设计提供参考。

关键词：催化转化器数学模型温度分布尾气转化率

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造纸废水灌溉的可行性及发展前景分析

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现代农业科技 2010年第24期 307-308页

作者：孔祥华宝鸡文理学院陕西省灾害监测与机理模拟重点实验室陕西宝鸡721013

分析造纸废水灌溉存在的一些问题及其可行性和发展前景,指出:污水灌溉要因地制宜、合理规划,灌溉前要对水质进行监测,且使用污水中的含量不能超过所灌溉土壤的净化能力。同时,要结合当地水源情况、土壤质地、作物种植的种类及生长阶段... 详细信息

分析造纸废水灌溉存在的一些问题及其可行性和发展前景,指出:污水灌溉要因地制宜、合理规划,灌溉前要对水质进行监测,且使用污水中的含量不能超过所灌溉土壤的净化能力。同时,要结合当地水源情况、土壤质地、作物种植的种类及生长阶段等情况,合理利用污水进行灌溉,这对缓解我国水资源日益紧张的供需矛盾,保护生态环境,提高经济效益有重要意义。

关键词：灌溉造纸废水可行性发展前景

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高氯代阻燃剂得克隆在环境中的分布与归趋

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江西农业学报 2011年第4期23卷 156-158页

作者：孔祥华宝鸡文理学院灾害监测与机理模拟陕西省重点实验室陕西宝鸡721013

得克隆(Dechlorane Plus,DP)是一类氯代脂肪族化合物,作为添加型阻燃剂广泛应用于电线电缆的涂层、电器的塑料高聚物、塑料屋顶材料领域。由于DP具有广泛的使用性和生物积累性,因此,现已成为环境中广泛存在的污染物,可能会对人体产生潜... 详细信息

得克隆(Dechlorane Plus,DP)是一类氯代脂肪族化合物,作为添加型阻燃剂广泛应用于电线电缆的涂层、电器的塑料高聚物、塑料屋顶材料领域。由于DP具有广泛的使用性和生物积累性,因此,现已成为环境中广泛存在的污染物,可能会对人体产生潜在的危害。从DP的理化特性和毒理学特性、环境中的浓度水平、异构体特性等方面进行了分析,并提出了今后的一些研究方向。

关键词：得克隆分布归趋环境

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The optimal atropine concentration for myopia control in Chinese children: a systematic review and network Metaanalysis

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International Journal of Ophthalmology(English edition) 2024年第6期17卷 1128-1137页

作者： Xiao-Yan Wang Hong-Wei Deng Jian Yang Xue-Mei Zhu Feng-Ling xiang Jing Tu Ming-Xue huang Yun Wang Jin-hua Gan Wei-hua Yang School of Nursing Southwest Medical UniversityLuzhou 646600Sichuan ProvinceChina Shenzhen Eye Institute Shenzhen Eye HospitalJinan UniversityShenzhen 518040Guangdong ProvinceChina Luzhou Traditional Chinese Medicine Hospital Luzhou 646000Sichuan ProvinceChina The Affiliated Hospital of Southwest Medical University Luzhou 646099Sichuan ProvinceChina

AIM:To figure out whether various atropine dosages may slow the progression of myopia in Chinese kids and teenagers and to determine the optimal atropine concentration for effectively slowing the progression of ***:A systematic search was conducted across the Cochrane Library,PubMed,Web of Science,EMBASE,CNKI,CBM,VIP,and Wanfang database,encompassing literature on slowing progression of myopia with varying atropine concentrations from database inception to January 17,*** extraction and quality assessment were performed,and a network Meta-analysis was executed using Stata version 14.0 *** were visually represented through ***:Fourteen papers comprising 2475 cases were included;five different concentrations of atropine solution were *** network Meta-analysis,along with the surface under the cumulative ranking curve(SUCRA),showed that 1%atropine(100%)>0.05%atropine(74.9%)>0.025%atropine(51.6%)>0.02%atropine(47.9%)>0.01%atropine(25.6%)>control in refraction change and 1%atropine(98.7%)>0.05%atropine(70.4%)>0.02%atropine(61.4%)>0.025%atropine(42%)>0.01%atropine(27.4%)>control in axial length(AL)***:In Chinese children and teenagers,the five various concentrations of atropine can reduce the progression of *** the network Meta-analysis showed that 1%atropine is the best one for controlling refraction and AL change,there is a high incidence of adverse effects with the use of 1%***,we suggest that 0.05%atropine is optimal for Chinese children to slow myopia progression.

关键词： atropine China children and adolescents myopia network Meta-analysis

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Plasmon-enhanced ultra-high photoresponse of single-wall carbon nanotube/copper/silicon near-infrared photodetectors

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Nano Research 2024年第7期17卷 5930-5936页

作者： Yi-Ming Zhao Xian-Gang Hu Chao Chen Zuo-hua Wang An-Ping Wu Hong-Wang Zhang Peng-xiang Hou Chang Liu Hui-Ming Cheng Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaShenyang 110016China National Engineering Research Center for Equipment and Technology of Cold Strip Rolling College of Mechanical EngineeringYanshan UniversityQinhuangdao 066004China Faculty of Materials Science and Engineering/Institute of Technology for Carbon Neutrality Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China

Single wall carbon nanotube(SWCNT)/Si heterojunction photodetectors have the advantages of high photoresponse ability and simple structure,however,their detection wavelength range are usually lower than 1100 nm,which limits their application in the infrared *** report a SWCNT/Cu/Si photodetector with both a high photoresponse and a detection range up to the infrared band by depositing a Cu nanoparticles(NPs)layer between a SWCNT film and a n-Si *** was found that the Cu NPs produce strong surface plasmon resonance(SPR)under laser irradiation,which breaks through the limitation of Si band gap and greatly improves the photoresponse of the SWCNT/Cu/Si photodetector in the near infrared *** responsivity(R)of the photodetector in the wavelength range of 1850–1200 nm reached 2.2–14.15 mA/W,which is the highest value in the reported plasmon enhanced n-Si based photodetectors,and about 20,000 times higher than that of a SWCNT/Si *** R value for 1550 nm wavelength used in optical communications reached~8.2 mA/W,which is 64%higher than the previously reported values of commonly used *** attribute the significant increase to the strong SPR and low Schottky barrier of Cu with n-Si,which facilitates the generation and transfer of the carriers.

关键词： single wall carbon nanotube photodetector silicon surface plasmon resonance copper

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Molecular solid solution of lanthanide-titanium-oxo clusters with enhanced photocatalytic hydrogen evolution

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Science China Chemistry 2024年第2期67卷 529-535页

作者： Rong Chen Chao-Long Chen Hui Zhang Zi-Han Wang Fu-Li Sun Ming-Hao Du Gui-Lin Zhuang Cheng Wang La-Sheng Long Lan-Sun Zheng xiang-Jian kong Collaborative Innovation Centre of Chemistry for Energy Materials State Key Laboratory of Physical Chemistry of Solid Surfaces and Department of Chemistry College of Chemistry and Chemical EngineeringXiamen UniversityXiamen361005China College of Chemical Engineering Zhejiang University of TechnologyHangzhou310032China

Molecular solid solutions of metal clusters containing different metal centers with well-defined structures can accurately regulate the HOMO-LUMO gap,but are rarely ***,a series of colorless lanthanide-titanium-oxo clusters Ln_(2)Ti_4(μ_(2)-O)_(2)(μ_(3)-O)_4(Piv)_(10)(THF)_(2)(Ln_(2)Ti_4,Ln = Eu,Gd,Tb,and Ce,HPiv = pivalic acid) were synthesized by the reaction of pivalic acid with Ln(Ac)_(3) and titanium *** light yellow crystal of cluster solid solutions Eu_(2)Ti_(4-x)Cd_(x),containing a mixture of Eu_(2)Ti_4 and Eu_(2)Ti_(3)Cd,was obtained by in situ doping Cd^(2+) and S^(2–).Eu_(2)Ti_(3.92)Cd_(0.08) displays efficient photocatalytic hydrogen evolution activity without a co-catalyst,which is up to 2.6 times that of Eu_(2)Ti_*** time-resolved transient absorption spectroscopy and spin-polarized density functional calculations showed that the enhanced photocatalytic performance of Eu_(2)Ti_(4-x)Cd_(x) can be attributed to the narrower HOMO-LUMO gap and lower LUMO position than that of Eu_(2)Ti_*** studyprovides an in situ doping method to realize the simple preparation of cluster solid solution.

关键词： molecular solid solution lanthanide-titanium-oxo clusters photocatalytic hydrogen evolution

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