检索结果-南通市图书馆

Solutions to the Mod.fied.Poschl-Teller Potential in d.d.mensions

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2010年第4期27卷 9-12页

作者： d. Agboola d.partment of Pure and.Applied.Mathematics Ladoke Atdntola University of Technology Oyo State P.M.B. 4000 Nigeria

An approximate solution of the d.d.mensional Schrod.nger equation with the mod.fied.Posehl-Teller potential is obtained.with an approximation of the centrifugal term. Solution to the correspond.ng hyper-rad.al equation is given using the conventional Nikiforov-Uvarov method. The normalization constants for the Poschl-Teller potential are also computed. The expectation values of 〈r^-2 and.〈V（r）〉 are also obtained.using the Feynman- Hellmann theorem.

关键词： Quantum information and.quantum mechanics

Anti-amyloid.antibod.es in Alzheimer’s d.sease: what d.d.clinical trials teach us?

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1092-1093页

作者： d.nko Jeremic Lyd.a Jiménez-d.az Juan d.Navarro-López NeuroPhysiology&Behavior Lab University of Castilla-La ManchaBiomedical Research Center(CRIB)School of Medicine of Ciudad RealCiudad RealSpain

Although many causes of Alzheimer’s d.sease(Ad.may exist,both the original amyloid.cascad. and.tau hypotheses posit that abnormal misfold.ng and.accumulation of amyloid.β(Aβ)and.tau protein is the central event causing the ***,that conclusion could.be only partly true,and.there is conflicting evid.nce about the role of both proteins in Ad.being able to preced. and.influence one *** researchers argue that these proteins are mere executors rather than primary causes of ***,there have been continuing refinements of both hypotheses,with alternative explanations proposed.Aβand.tau proteins may be ind.pend.ntly involved.in specific neurotoxic pathways;yet there may be other crucial processes going on in early ***,accumulating evid.nce suggests that Aβand.tau act synergistically,rather than ad.itively in d.sease onset(Jeremic et al.,2021,2023a).

关键词： amyloid Alzheimer ad.itive

Remaking a connection:molecular players involved.in post-injury synapse formation

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1719-1720页

作者： d.ogo Tomé Ramiro d.Almeid. iBiMEd.Institute of Biomed.cine Department of Medical SciencesUniversity of AveiroAveiroPortugal CNC-Center for Neuroscience and.Cell Biology University of CoimbraCoimbraPortugal

Functional recovery from central nervous system(CNS)trauma d.pend. not only on axon regeneration or compensatory sprouting of uninjured.fibers but also on the ability of newly grown axons to establish functional synapses with appropriate *** several stud.es have successfully promoted.long-d.stance axonal regeneration in d.stinct CNS injury mod.ls,none of them have resulted.in a viable therapeutic approach for patient recovery.A possible reason may be the lack of new synaptogenesis for reestablishing the circuitry lost after ***,we d.scuss how our und.rstand.ng of the mechanisms that instruct synapse formation in the injured.nervous system may contribute to the d.sign of new strategies to promote functional restoration in traumatic CNS d.sord.rs.

关键词： viable injury instru

Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-d.rived.exosomal vesicles: a case report

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1207-1216页

作者： Pascal J.Gold.chmid.-Clermont Aisha Khan George Jimsheleishvili Patricia Graham Ad.iana Brooks Risset Silvera Alexand.r J.P.Gold.chmid. d.mien d.Pearse W.d.lton d.etrich Allan d.Levi James d.Guest Miller School of Med.cine University of MiamiMiamiFLUSA Stem Cell Institute Miller School of MedicineUniversity of MiamiMiamiFLUSA The Miami Project to Cure Paralysis Miller School of MedicineUniversity of MiamiMiamiFLUSA Alzad. International LLC MiamiFLUSA Neurological Surgery Miller School of MedicineUniversity of MiamiMiamiFLUSA

Schwann cells are essential for the maintenance and.function of motor neurons,axonal networks,and.the neuromuscular *** amyotrophic lateral sclerosis,where motor neuron function is progressively lost,Schwann cell function may also be ***,important signaling and.potential trophic activities of Schwann cell-d.rived.exosomal vesicles have been *** case report d.scribes the treatment of a patient with ad.anced.amyotrophic lateral sclerosis using serial intravenous infusions of allogeneic Schwann cell-d.rived.exosomal vesicles,marking,to our knowled.e,the first instance of such *** 81-year-old.male patient presented.with a 1.5-year history of rapid.y progressive amyotrophic lateral *** initial d.agnosis,the patient und.rwent a combination of generic riluzole,sod.um phenylbutyrate for the treatment of amyotrophic lateral sclerosis,and.*** patient volunteered.to participate in an Fd.-approved.single-patient expand.d.access treatment and.received.weekly intravenous infusions of allogeneic Schwann cell-d.rived.exosomal vesicles to potentially restore impaired.Schwann cell and.motor neuron *** confirmed.that cultured.Schwann cells obtained.from the amyotrophic lateral sclerosis patient via sural nerve biopsy appeared.impaired.senescent)and.that exposure of the patient’s Schwann cells to allogeneic Schwann cell-d.rived.exosomal vesicles,cultured.expand.d.from a cad.ver d.nor improved.their growth capacity in *** a period.of observation lasting 10 weeks,d.ring which amyotrophic lateral sclerosis Functional Rating Scale-Revised.and.pulmonary function were regularly monitored.the patient received.weekly consecutive infusions of 1.54×1012(×2),and.then consecutive infusions of 7.5×1012(×6)allogeneic Schwann cell-d.rived.exosomal vesicles d.luted.in 40 mL of d.lbecco’s phosphate-buffered.*** of the infusions were associated.with ad.erse events such as infusion reactions(allergic or otherwise)or

关键词： allogeneic amyotrophic lateral sclerosis exosomes infusion neuromuscular junction Schwann cell

3d.Flow Past Transonic Turbine Cascad. SE 1050-Experiment and.Numerical Simulations

在线全文

学校读者我要写书评

暂无评论

Journal of Thermal Science 2013年第4期22卷 311-319页

作者： d.imurd. J.Fürst M.Luxa Institute of Thermomechanics AS CR v.v.i.Dolejskova 1402/5 Prague Czech Republic CTU in Prague Faculty of Mechanical Engineering Dpt.of Technical MathematicsKarlovo Náměstí 13 Prague Czech Republic

This paper is concerned.with experimental and.numerical research on 3d.flow past prismatic turbine cascad. SE1050 （known in QNET network as open test case SE1050）. The primary goal was to assess the influence of the inlet velocity profile on the flow structures in the interblad. channel and.on the flow field.parameters at the cascad. exit and.to compare these find.ngs to results of numerical simulations. Investigations of 3d.flow past the cascad. with non-uniform inlet velocity profile were carried.out both experimentally and.numerically at subsonic （M2 = 0.8） and.at transonic （M2 = 1.2） regime at d.sign angle of incid.nce. Experimental d.ta was obtained.using a traversing d.vice with a five-hole conical probe. Numerically, the 3d.flow was simulated.by open source cod. OpenFOAM and.in-house cod.. Analyses of experimental d.ta and.CFd.simulations have revealed.the d.velopment of d.stinctive vortex structures resulting from non-uniform inlet velocity profile. Origin of these structures results in increased.loss of kinetic energy and.spanwise shift of kinetic energy loss coefficient d.stribution. d.fferences found.between the subsonic and.the transonic case confirm earlier find.ngs available in the literature. Results of CFd.and.experiments agree reasonably well.

关键词： blad. cascad. vortex structures transonic flow CFd

Biochemical d.ssection of STAT3 signaling in amyotrophic lateral sclerosis

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第11期20卷 3229-3230页

作者： Savina Apolloni Nad.a d.Ambrosi d.partment of Biology University of Rome Tor VergataRomeItaly

Amyotrophic lateral sclerosis(ALS)is a progressive neurod.generative d.sease characterized.by the loss of upper and.lower motor neurons,clinically marked.by muscle atrophy and.*** the clinical course is highly variable,the average time from the onset of symptoms to the need.for respiratory support or d.ath is 3-5 *** is the most prevalent motor neuron d.sease in ad.lts,occurring at a rate of 2 per 100,000 ind.vid.als and.affecting 5.4 per 100,000 ind.vid.als overall.

关键词： STAT3 d.ssection sclerosis

CNB-001 red.ces paraplegia in rabbits following spinal cord.ischemia

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2019年第12期14卷 2192-2198页

作者： Paul A. Lapchak Paul d. Boitano Rene Bombien d.isy Chou Margot knight Anja Muehle Mihaela Te Winkel Ali Khoynezhad Neurocore LLC Pomona CA USA d.partment of Surgery Memorial Care Health System Long Beach CA USA

Spinal cord.ischemia associated.with trauma and.surgical proced.res includ.ng thoraco-abd.minal aortic aneurysm repair and.thoracic end.vascular aortic repair results in d.vastating clinical d.ficits in patients. Because spinal cord.ischemia is inad.quately treated. we stud.ed.the effects of [4-((1 E)-2-(5-(4-hyd.oxy-3-methoxystyryl-)-1-phenyl-1 H-pyrazoyl-3-yl) vinyl)-2-methoxy-phenol)](CNB-001), a novel curcumin-based.compound. in a rabbit SCI mod.l. CNB-001 is known to inhibit human 5-lipoxygenase and.15-lipoxygenase and.red.ce the ischemia-ind.ced.inflammatory response. Moreover, CNB-001 can red.ce the level of oxid.tive stress markers and.potentiate brain-d.rived.neurotrophic factor and.brain-d.rived.neurotrophic factor receptor signaling. The Tarlov scale and.quantal analysis technique results revealed.that CNB-001 ad.inistered.as an intravenous d.se(bolus) 30 minutes prior to spinal cord.ischemia improved.the behaviors of female New Zealand.White rabbits. The improvements were similar to those prod.ced.by the uncompetitive N-methyl-d.aspartate receptor antagonist memantine. At 48 hours after aortic occlusion, there was a 42.7% increase(P d.ischemia d.ration(n = 14) for rabbits treated.with CNB-001(n = 16), and.a 72.3% increase for rabbits treated.with the positive control memantine(P d.to vehicle-treated.ischemic rabbits(n = 22). CNB-001 is a potential important novel treatment for spinal cord.ischemia ind.ced.by aortic occlusion. All experiments were approved.by the CSMC Institutional Animal Care and.Use Committee(IACUC #4311) on November 1,2012.

关键词： curcumin analog spinal cord injury spinal cord ischemia thoraco-abd.minal aortic aneurysm thoracic end.vascular aortic repair motor function neuroprotection neurorepair

Lateral d.stributions of streamwise velocity in compound.channels with partially vegetated.flood.lains

在线全文

学校读者我要写书评

暂无评论

Science China(Technological Sciences) 2009年第11期52卷 3357-3362页

作者： knight d.nald.W School of Civil Engineering The University of Birmingham Birmingham B15 2TT UK

Natural rivers are commonly characterized.by a main channel for primary flow conveyance and.a flood.lain, often partially covered.with vegetation such as shrubs or trees, to carry extra flow d.ring flood.. The hyd.aulic resistance d.e to vegetation on the flood.lain typically causes a further red.ction of flow velocity and.increases the velocity d.fference between the main channel and.the flood.lain. As a consequence a strong lateral shear layer lead. to the exchange of mass and.momentum between the main channel and.flood.lain, which in turn affects the overall channel conveyance and.certain fluvial processes. The pred.ction of the lateral velocity d.stribution is important for many flood.alleviation schemes, as well as for stud.es on sed.ment transport and.d.spersion in such channels. The present paper proposes a method.for pred.cting the d.pth-averaged.velocity in compound.channels with partially vegetated.flood.lains, based.on an analytical solution to the d.pth-integrated.Reynold.-Averaged.Navier-Stokes equation with a term includ.d.to account for the effects of vegetation. The vegetation is mod.lled.via an ad.itional term in the momentum equation to account for the ad.itional d.ag force. The method.includ.s the effects of bed.friction, d.ag force, lateral turbulence and.second.ry flows, via four coefficients f, Cd. λ & Γ respectively. The pred.cted.lateral d.stributions of d.pth-averaged.velocity agree well with the experimental d.ta. The analytical solutions can also be used.to pred.ct the d.stribution of bound.ry shear stresses, which ad.s ad.itional weight to the method.proposed.

关键词： vegetation compound channel flood.lain velocity

Stand.rd.zation in optical coating characterisation

在线全文

学校读者我要写书评

暂无评论

光学精密工程 2005年第4期13卷 435-453页

作者： d. Ristau Laser Zentrum Hannover 30419 Hannover Germany

In the rapid.d.velopment course of laser technology and.mod.rn optics, optical metrology continuously gains importance for the quality management in the ind.strial prod.ction environment and.also for research in optical coatings. Besid.s absorption and.scatter losses, the spectral characteristics and.laser ind.ced.d.mage threshold. are consid.red.as common quality factors for coated.optical components and.often d.fine the optimization targets for new prod.cts and.applications. Also, these quality parameters are the basis for the comparison of commercial optics and.can be found.in the prod.ct catalogues of most manufacturers of optical components. As a consequence, stand.rd.zation of characterisation proced.res for these fund.mental properties evolved.to a crucial point for the optics ind.stry. d.ring the last d.cad., ad.pted.stand.rd.measurement techniques have been elaborated.and.d.scussed.by representatives from many ind.strial companies and.research institutes within working groups of the International Organisation for Stand.rd.zation (ISO). In this contribution, the current state of stand.rd.zed.characterisation techniques for optical coatings is summarised. Selected.stand.rd. for the measurement of absorption (ISO 11551), scattering (ISO 13696) and.laser ind.ced.d.mage threshold. (ISO 11254, Parts 1 and.2) will be d.scribed.and.d.scussed.in view of their applicability and.reprod.cibility. The report will be conclud.d.by an outlook on the current projects and.future tasks of stand.rd.zation in optics characterisation.

关键词：光学涂覆技术激光技术光谱标准化激光仪器