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中日岩土工程学术会议

作者： KIYOSHI OMINE HIDETOSHI OCHIAI NORIYUKI YASUFUKU TAIZO KOBAYASHI keiichirou kuroki MASUHITO SHIOZAK Associate Professor Department of Civil EngineeringKyushu University6-10-1 HakozakiHigashi-kuFukuoka 812-8581Japan Associate Professor Department of Civil Engineering Kyushu University 6-10-1 Hakozaki Higashi-ku Fukuoka 812-8581 Japan Deputy manager Kurimoto Ltd. Kyushu BrachHakata-kuFukuokaJapan

＜正＞ In order to improve the mechanical properties of volcanic cohesive soils, they are usually stabilized by adding cement or lime. However, this method has certain drawbacks such as insufficient hardening or the leaching of hexavalent chromium from cement. Each year, a large amount of mown grass is generated from embankments and river areas. Most of this grass is either burnt in a field or disposed, while a part of it is used in composting. A technique for the carbonization of mown grass has been developed. Carbide is a porous material with a high capacity for water absorption. Therefore, the mown grass carbide can be used for water purification and soil improvement. In this study, the strength and leaching properties of cement-treated soils mixed with charcoal are investigated by performing unconfined compression and by conducting leaching tests. Furthermore, a cone penetration test is performed on the volcanic cohesive soils using the carbide obtained from mown grass, and the improvement in trafficability by mixing carbide and lime is clarified.

关键词： Volcanic Cohesive Soils Carbide Cone Penetration Test Trafficability

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Correlation of N-myc downstream-regulated gene 1 expression with clinical outcomes of colorectal cancer patients of different race/ethnicity

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World Journal of Gastroenterology 2007年第20期13卷 2803-2810页

作者： Minori Koshiji Kensuke Kumamoto keiichirou Morimura Yasufumi Utsumi Michiko Aizawa Masami Hoshino Shinji Ohki Seiichi Takenoshita Max Costa Thérèse Commes David Piquemal Curtis C Harris Kam-Meng Tchou-Wong Department of Environmental Medicine New York University School of Medicine 57 Old Forge Road Tuxedo NY 10987 United States Shinji Ohki Seiichi Takenoshita Second Department of Surgery Fukushima Medical University 1 Hikarigaoka Fukushima 960-1295 Japan Curtis Harris National Institutes of Health National Cancer Institute Building 37 Bethesda MD 20892 United States Department of Pathology Osaka City University Osaka Japan Department of Pathology Ohara General Hospital 6-11 Ohmachi Fukushima 960-8611 Japan Department of Surgery Ohara General Hospital 6-11 Ohmachi Fukushima 960-8611 Japan David Piquemal University Montpellier Ⅱ Montpellier France

AIM： To evaluate the role of N-myc downstream- regulated gene 1 （NDRG1） expression in prognosis and survival of colorectal cancer patients with different ethnic backgrounds. METHODS： Because NDRG1 is a downstream target of p53 and hypoxia inducible factor-1α （HIF-1α）, we examined NDRG1 expression together with p53 and HIF-1α by irnmunohistochernistry. A total of 157 colorectal cancer specimens including 80 from Japanese patients and 77 from US patients were examined. The correlation between protein expression with clinicopathological features and survival after surgery was analyzed. RESULTS： NDRG1 protein was significantly increased in colorectal tumor compared with normal epithelium in both Japanese and US patient groups. Expression of NDRG1 protein was significantly correlated with lymphatic invasion, venous invasion, depth of invasion, histopathological type, and Dukes＇ stage in Japanese colorectal cancer patients. NDRG1 expression was correlated to histopathological type, Dukes＇ stage and HIF-1α expression in US-Caucasian patients but not in US-African American patients. Interestingly, Kaplan-Meier survival analysis demonstrated that NDRG1 expression correlated significantly with poorer survival in US-African American patients but not in other patient groups. However, in p53-positive US cases, NDRG1 positivity correlated significantly with better survival. In addition, NDRG1 expression also correlated significantly with improved survival in US patients with stages Ⅲ and IV tumors without chemotherapy. In Japanese patients with stages Ⅱ and Ⅲ tumors, strong NDRG1 staining in p53- positive tumors correlated significantly with improved survival but negatively in patients without chemotherapy. CONCLUSION： NDRG1 expression was correlated with various clinicopathological features and clinical outcomes in colorectal cancer depending on the race/ethnicity of the patients. NDRG1 may serve as a biological basis for the disparity of clinical outcomes of colorectal canc

关键词： NDRG1 expression Colorectal cancer Race Ethnicity Clinical outcomes

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日本海里号HB-E300系普通型混合动力观光动车组概况

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国外铁道机车与动车 2021年第4期 26-30页

作者： [日]安在惠一郎彭惠民(译) 石炜(校) 不详

东日本铁路客运公司为实现"变革2027"目标,积极开拓观光旅游市场以满足乘客旅游出行的需求。为配合新泻县庄内的地方旅游目的地宣传活动,新造了海里号HB-E300系新款观光列车。介绍该型动车组的设计理念、主要技术参数、客室结构布局、... 详细信息

东日本铁路客运公司为实现"变革2027"目标,积极开拓观光旅游市场以满足乘客旅游出行的需求。为配合新泻县庄内的地方旅游目的地宣传活动,新造了海里号HB-E300系新款观光列车。介绍该型动车组的设计理念、主要技术参数、客室结构布局、服务设施及相关技术与装备。

关键词：混合动力动车组技术参数车内服务设施结构

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