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Genomic Characterization of the First Sequenced Clinical Legionella micdadei Isolate from China

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Biomedical and Environmental Sciences 2023年第2期36卷 185-190页

作者： CHEN Ai ping ZHANG Yong jun Chongqing Medical and Pharmaceutical College Chongqing 401331China Chongqing Municipal Key Laboratory for High Pathogenic Microbes Chongqing 400042China

Since Legionella pneumophila(***)was identified in 1976 as the causative microorganism for severe pneumonia termed Legionnaires Disease(LD),more than 65 species belonging to the genus Legionella have been isolated worldwide[1].Approximately 20 Legionella *** been documented to be pathogenic in humans,primarily leading to transient flu-like illness(Pontiac fever)or rapid and potentially fatal pneumonia(LD).

关键词： Clinical primarily transient

Nanoplatform-based cellular reactive oxygen species regulation for enhanced oncotherapy and tumor resistance alleviation

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Chinese Chemical Letters 2023年第9期34卷 85-99页

作者： Meifang Wang ping’an Ma jun Lin State Key Laboratory of Rare Earth Resource Utilization Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun 130022China

The cancer cells realize their proliferation and metastasis activities based on the special redox adaptation to increased reactive oxygen species(ROS)level,which inversely makes them sensitive to external interference with their redox *** view of this,in recent decades,researchers have made great efforts to construct a series of novel nanoplatform-based ROS-mediated cancer therapies through increasing ROS generation and inhibiting the ROS ***,the multidrug resistance and thermoresistance of tumor are closely related to tumor redox ***,numerous works have shown that ROS regulation in cancer cells can intervene in the expression,function and stability of related proteins to achieve reversal of tumor *** this review,the recent researches about ROS-regulating nanoagents on cancer therapy and tumor resistance alleviation have been well ***,the challenges and research directions of ROS-regulating nanoagents for future clinical translation are also discussed.

关键词： Nanoagents ROS regulation ROS-mediated cancer therapy Multidrug resistance Thermoresistance

Selection of female parents with high fertility and high combining abilities for cross-breeding Populus tomentosa

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Journal of Forestry Research 2019年第2期30卷 445-450页

作者： Feng-ying Bai Ning kang ping-dong Zhang Xiang-yang kang National Engineering Laboratory for Tree Breeding Beijing Advanced Innovation Center for Tree Breeding by Molecular Design Beijing Laboratory of Urban and Rural Ecological Environment Beijing Forestry University

To select maternal parents with high fertility and high combining ability during cross breeding of Populus tomentosa Carr., the ploidy level of 75 female clones was determined using flow cytometry. In addition, genetic variations and phenotypic correlations of seed traits and early growth traits, as well as the general combining ability(GCA) for seedling height(SH) and basal diameter(BD) of all diploid half-sib families were examined. A total of 26 natural triploid clones were identified. For all diploid families, family effects were significant for inflorescence length(IL), thousand kernel weight(TKW), seedling emergence rate(SER), and for SH and BD. There was a positive correlation between TKW and other traits,excluding IL. The seed-bearing coefficient(NS 9 SER)ranged from zero to 32.4%. Clones 3-10-2, 2-8, 3119,3206, and 3-10-1 had the best performance of the GCA for SH and BD. Based on the fertility and GCA for SH and BD, clone 3-10-2 and clone 3119 could be used as female parents for controlled cross-breeding of P. tomentosa.

关键词： Fertility ability General combining ability Genetic variation Half-sib family Populus tomentosa

A synthesizing control model of networked control systems to guarantee QoP and QoS

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控制理论与应用（英文版） 2008年第4期6卷 379-384页

作者： jun kang Guanzhong DAI College of Automation Northwestern Polytechnical University Xi＇an Shannxi 710072 China

The whole performance of the networked control system （NCSs） depends on two interaction factors, namely the quality of control performance （QoP） and quality of network service （QoS）. So, to optimize the whole perfor-mance of NCSs, the problem of guaranteeing QoP and QoS plays an important role in the design of NCSs. However, up to now, little work has been done in this field. In this paper, a synthesizing control model of NCSs to guarantee QoP and QoS is proposed, and a feasible condition of optimizing whole performance of NCSs is also suggested. Finally, the simulation results show that the proposed model is effective.

关键词： Networked control system (NCSs) Synthesizing control Quality of control performance (QoP) Quality of network service (QoS)

A Full-Scale Optimization of a Crop Spatial Planting Structure and its Associated Effects

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Engineering 2023年第9期28卷 139-152页

作者： Qi Liu jun Niu Taisheng Du Shaozhong kang Center for Agricultural Water Research in China China Agricultural UniversityBeijing 100083China State Key Laboratory of Efficient Utilization of Agricultural Water Resources Beijing 100083China National Field Scientific Observation and Research Station on Efficient Water Use of Oasis Agriculture in Wuwei of Gansu Province Wuwei 733000China Key Laboratory of Agricultural Water Saving of the Ministry of Water Resources Beijing 100083China

Driven by the concept of agricultural sustainable development,crop planting structure optimization(CPSO)has become an effective measure to reduce regional crop water demand,ensure food security,and protect the ***,traditional optimization of crop planting structures often ignores the impact on regional food supply–demand relations and interprovincial food ***,using a system analysis concept and taking virtual water output as the connecting point,this study proposes a theoretical CPSO framework based on a multi-aspect and full-scale evaluation index *** this end,a water footprint(WF)simulation module denoted as soil and water assessment tool–water footprint(SWAT-WF)is constructed to simulate the amount and components of regional crop WFs.A multi-objective spatial CPSO model with the objectives of maximizing the regional economic water productivity(EWP),minimizing the blue water dependency(BWFrate),and minimizing the grey water footprint(GWFgrey)is established to achieve an optimal planting *** various benefits,a fullscale evaluation index system based on region,province,and country scales is *** an entropy weight technique for order preference by similarity to an ideal solution(TOPSIS)comprehensive evaluation model,the optimal plan is selected from a variety of CPSO *** proposed framework is then verified through a case study of the upper–middle reaches of the Heihe River Basin in Gansu province,*** combining the theory of virtual water trading with system analysis,the optimal planting structure is *** sacrificing reasonable regional economic benefits,the optimization of the planting structure significantly improves the regional water resource benefits and ecological benefits at different scales.

关键词： Planting structure optimization Full-scale evaluation index system Water footprint SWAT-WF module Interprovincial food trade Entropy weight TOPSIS

Microstructural evolution of titanium matrix composite coatings reinforced by in situ synthesized TiB and TiC by laser cladding

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International Journal of Minerals,Metallurgy and Materials 2010年第4期17卷 481-488页

作者： jun Li Zhi-shui Yu Hui-ping Wang Man-ping Li School of Materials Engineering Shanghai University of Engineering Science Shanghai 201620 China

Titanium-based composite coatings reinforced by in situ synthesized TiB and TiC particles were successfully fabricated on Ti6Al4V by laser cladding using Ti-B_4C-Al or Ti-B_4C-C-Al powders as the precursor *** microstructural and metallographic analyses were made by X-ray diffraction（XRD）,optical microscope（OM）,scanning electron microscopy（SEM）,and electron probe microanalysis （EPMA）.The results show that the coatings are mainly composed ofα-Ti cellular dendrites and a eutectic transformation product in which a large number of coarse and fine needle-shaped TiB and a few equiaxial TiC particles are homogeneously embedded.A thin dilution zone with a thickness of about 100μm is present at the interface,and it consists of a few TiB and TiC reinforcements and a large number of lamella grains growing parallel to the heat flux direction in which a thin needle-shaped microstructure exists due to the martensitic transformation. The microstructural evolution can be divided into four stages：precipitation and growth of primaryβ-Ti phase,formation of the binary eutecticumβ-Ti＋TiB,formation of the ternary eutecticumβ-Ti＋TiB＋TiC,and solid transformation fromβ-Ti toα-Ti.

关键词： coating laser cladding in-situ synthesis microstructure

A novel method of constructing high-dimensional digital chaotic systems on finite-state automata

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Chinese Physics B 2020年第9期29卷 233-243页

作者： jun Zheng Han-ping Hu School of Artificial Intelligence and Automation Huazhong University of Science and TechnologyWuhan 430074China Key Laboratory of Image Information Processing and Intelligent Control Ministry of EducationWuhan 430074China

When chaotic systems are implemented on finite precision machines, it will lead to the problem of dynamical degradation. Aiming at this problem, most previous related works have been proposed to improve the dynamical degradation of low-dimensional chaotic maps. This paper presents a novel method to construct high-dimensional digital chaotic systems in the domain of finite computing precision. The model is proposed by coupling a high-dimensional digital system with a continuous chaotic system. A rigorous proof is given that the controlled digital system is chaotic in the sense of Devaney's definition of chaos. Numerical experimental results for different high-dimensional digital systems indicate that the proposed method can overcome the degradation problem and construct high-dimensional digital chaos with complicated dynamical properties. Based on the construction method, a kind of pseudorandom number generator (PRNG) is also proposed as an application.

关键词： high-dimensional digital chaotic system dynamical degradation anti-control pseudorandom number generator

Novel synthesis of aluminum hydroxide gel-coated nano zero-valent iron and studies of its activity in flocculation-enhanced removal of tetracycline

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Journal of Environmental Sciences 2020年第3期32卷 194-205页

作者： Xiangyu Wang Binbin Zhang jun Ma ping Ning Faculty of Environmental Science and Engineering Kunming University of Science and TechnologyKunming 650500China School of Environment Harbin Institute of TechnologyHarbin 150090China

A newly designed aluminum hydroxide gel-coated nanoscale zero-valent iron(AHG@NZVI)with enhanced activity and dispersibility of NZVI was successfully *** AHG@NZVI composite was synthesized via control of the surface AHG ***@NZVI-1,AHG@NZVI-2 and AHG@NZVI-3 were prepared under centrifugal mixing speeds of 1000,2000 and 4000 r/min,*** activity of AHG@NZVI was evaluated by its tetracycline(TC) removal *** effects of AHG content,pH value,reaction temperature,and presence of competitive anions on TC removal were *** could be removed by both adsorption and chemical reduction on AHG@NZVI-2(centrifugal speed 2000 r/min) in a short time with high removal efficiency(≥98.1%) at the optimal *** excellent performance can be attributed to a synergistic interaction between aluminum hydroxide gel and NZVI:(1) AHG could enhance the stability and dispersity of NZVI;(2) aluminum hydroxide gel could absorb a certain amount of TC and Fe^2+/Fe^3+,which facilitated the mass transfer of TC onto the NZVI surface,resulting in acceleration of the reduction rate of TC by the AHG@NZVI composite;and(3) AHG-Fe^2+/Fe^3+could absorb a certain amount of TC by *** kinetics of TC removal by AHG@NZVI composite was found to follow a two-parameter pseudo-first-order *** presence of competitive anions slightly inhibited the activity of AHG@NZVI systems for TC ***,this study provides a promising alternative material and environmental pollution management option for antibiotic wastewater treatment.

关键词： Nanoscale zerovalent iron Aluminum hydroxide gel Synergistic effect Tetracycline Flocculation

Static Schedule Generation for Time-Triggered Ethernet Based on Fuzzy Particle Swarm Optimization

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Chinese Journal of Electronics 2019年第6期28卷 1250-1258页

作者： CHEN Huang WANG Lide SHEN ping DI jun School of Electrical Engineering Beijing Jiaotong University

In time-triggered ethernet(TTEthernet),designing and optimizing the static scheduling of TT messages to improve the real-time performance of the whole network control system is important. When there is a high load on TTEthernet network communication,the conventional static scheduling policy introduces certain problems, such as increased packet loss rate,load imbalance, and transmission delay. Meanwhile,basic artificial intelligence algorithms generally features convergence within only a few steps, leading to higher probability to fall into a local optimal solution. To realize these targets, Fuzzy particle swarm optimization(FPSO)based on population diversity is established. By combining Particle swarm optimization(PSO) with a fuzzy algorithm,setting the adjustment of the inertia weight and the regulation of the mutation factor as the controlled variables of the Fuzzy logic controller(FLC), and adjusting the FLC inference rules, a novel static schedule generation for TTEthernet is proposed. Simulation results prove that,compared to the conventional rate-monotonic scheduling algorithm and the PSO algorithm, FPSO has a strong global search capability when the communication of the TTEthernet system is in a high-load state. FPSO improves the load balancing of the network and reduces the transmission delay of TT message packets. FPSO shows excellent ability to optimize scheduling tables and guarantee the real-time performance of the TTEthernet system.

关键词： Time-triggered ethernet(TTEthernet) Static schedule generation Fuzzy particle swarm optimization(FPSO) Fuzzy logic controller(FLC) Mutation factor Real-time performance Load balancing Transmission delay