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Liver transplantation following two conversions in a patient with huge hepatocellular carcinoma and portal vein invasion:A case report

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World Journal of Gastroenterology 2024年第36期30卷 4071-4077页

作者： Li-Cong Liang Wen-Sou Huang Zhao-Xiong Guo Hong-Ji You Yong-Jian Guo Ming-Yue Cai Li-Teng Lin Guo-Ying Wang kang-shun Zhu Department of Minimally Invasive Interventional Radiology The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260Guangdong ProvinceChina Department of Nuclear Medicine The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260Guangdong ProvinceChina Department of Hepatobiliary Surgery The First Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510120Guangdong ProvinceChina

BACKGROUND Surgical resection and liver transplantation(LT)are the most effective curative options for hepatocellular carcinoma(HCC).However,few patients with huge HCC(>10 cm in diameter),especially those with portal vein tumor thrombus(PVTT),can receive these *** internal radiation therapy(SIRT)can be used as a conversion therapy for them because it has the dual benefit of shrinking tumors and increasing residual hepatic ***,in patients with huge HCC,high lung absorbed dose often prevents them from receiving *** SUMMARY A 35-year-old man was admitted because of emaciation and pain in the hepatic region for about 1 *** computed tomography scan showed a 20.2 cm×19.8 cm tumor located in the right lobe–left medial lobes with right portal vein and right hepatic vein *** the pathological type of HCC was confirmed by biopsy,two conversions were *** first one was drug-eluting bead transarterial chemoembolization plus hepatic arterial infusion chemotherapy and lenvatinib and sintilimab,converted to SIRT,and the second one was sequential SIRT with continued systemic *** tumor size significantly decreased from 20.2 cm×19.8 cm to 16.2 cm×13.8 cm,then sequentially to 7.8 cm×6.8 *** the meantime,the ratio of spared volume to total liver volume increased gradually from 34.4%to 55.7%,then to 62.9%.Furthermore,there was visualization of the portal vein,indicating regression of the tumor ***,owing to the new tumor in the left lateral lobe,the patient underwent LT instead of resection without major *** Patients with inoperable huge HCC with PVTT could be converted to SIRT first and accept surgery sequentially.

关键词： Hepatocellular carcinoma Two conversions Liver transplantation Yttrium-90 resin microspheres Transarterial chemoembolization Hepatic arterial infusion chemotherapy Case report

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AN APPLICATION OF TOPOLOGICAL METHOD TO ANALYSING THE THREE-DIMENSIONAL FLOW IN CASCADES(Ⅱ)-TOPOLOGICAL ANALYSIS ON THE VECTOR FIELD PATTERNS OF SKINFRICTIONS AND SECTION STREAMLINES

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Applied Mathematics and Mechanics(English Edition) 1990年第12期11卷 1119-1127页

作者： kang shun Wang Zhongqi Harbin Instilule of Technology Harbin

With an application of topological analysis,in this paper the skin-friction line patterns on compressor and turbine cascade surfaces are depicted and the streamline patterns of the secondary flow fields in the cross-section of a curved pipe and a turbine cascade are drawn under given *** addition the structures of vortices within three-dimensional viscous flow fields in cascades are analysed.

关键词： topological analysis separation flow three-dimensional flow visualization turbine compressor vortex

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Effect of DBD plasma excitation characteristics on turbulent separation over a hump model

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Plasma Science and Technology 2018年第10期20卷 135-145页

作者： Lu MA Xiaodong WANG Jian ZHU shun kang Key Laboratory of Condition Monitoring and Control for Power Plant Equipment Ministry of EducationNorth China Electric Power UniversityBeijing 102206People＇s Republic of China

In this paper, the effect of dielectric-barrier discharge plasma excitation characteristics on turbulent boundary layer separation over a hump is investigated using computational fluid dynamics. Four different turbulence models were used for verification. The Reynolds stress model showed the best agreement with the experimental data, in general. Based on the verification and validation, the effect of duty cycle and excitation frequency on the turbulent flow separation were investigated. The results showed that the pulsed plasma excitation could effectively suppress the flow separation by mixing augmentation. With increasing duty cycle and excitation frequency, the flow separation first increased, then decreased again. The optimal duty cycle was 0.75 and the optimal excitation frequency was 50 Hz.

关键词： flow control numerical simulation DBD plasma excitation frequency

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Investigation of film cooling on the leading edge of turbine blade based on detached eddy simulation

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Science China(Technological Sciences) 2012年第9期55卷 2191-2198页

作者： LIANG JunYu kang shun Key Laboratory of Condition Monitor and Control for Power Plant Equipment of Ministry of Education North China Electric Power UniversityBeijing 102206China

In order to assess the influences of curved hole passage on cooling effectiveness and flow structure of turbine blade leading edge,the detached eddy simulation is applied to numerically investigate the AGTB turbine cascade under the condition of global blowing ratio M=*** straight or curved cooling holes are located at either the pressure or suction side near the leading *** analysis and discussion focus on the local turbulence structure;influence of pressure gradient on the structure,and distribution of cooling effectiveness on the blade *** numerical results show that cooling hole with curved passage could bring positive impact on the increase of the local cooling *** the suction side,the increased cooling effectiveness could be about 82% and about 77% on the pressure side,compared to the conventional straight hole.

关键词： film cooling blade leading edge detached eddy simulation cooling effectiveness coherent structure

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Exploration of Waterproofness of Concrete and Alkali-Aggregate Using Hydrophobic Impregnation and Coating

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Journal of Renewable Materials 2022年第12期10卷 3521-3538页

作者： shun kang Xun Yuan Changwu Liu Yulin Chen Xianliang Zhou Haikuan Wu Zhiguo Ma College of Water Resource and Hydropower Sichuan UniversityChengduChina School of Emergency Science Xihua UniversityChengduChina Sichuan Chuanjiao Road and Bridge Co. Ltd.GuanghanChina

Part of the tunnel spoil can not be used for concrete due to alkali aggregate reaction(AAR).Water is an indis-pensable condition for AAR,so separating the alkali-aggregate from water is of great benefit to controlling the *** paper investigates the modification of concrete and aggregate by hydrophobic impregnation and organic coating and then evaluates their waterproof and me chanical properties by dynamic contact angle(DCA),ultrasonic wave velocity,scanning electron microscope(SEM),nuclear magnetic resonance(NMR),and so *** waterproofness,hydrophobic impregnation and organic coating can both improve the waterproof-ness of concrete and *** organic coating is suitable for aggregate because it wrap aggregate *** aggregate coated by PVA can improve the interfacial transition zone(ITZ).For mechanical properties,both mate-rials will weaken the strength of the ***,concrete made by aggregate with organic coating shows plastic deformation and has a good correlation with the film thickness,a plastic estimation model based on flm thickness is *** paper evaluates the waterproof of concrete and aggregate and finds plastic con-crete with good aggregate waterproofness which provides a new idea for the application of alkali aggregate in see-page control facilities of water conservancy projects.

关键词： Alkali aggregate SEM NMR PVA

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Investigations on methane hydrate formation,dissociation,and viscosity in gas-water-sand system

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Petroleum Science 2022年第5期19卷 2420-2430页

作者： Shang-Fei Song shun-kang Fu Qing-Yun Liao Bo-Hui Shi Hong-Ju Chen Jing Gong State Key Laboratory of Natural Gas Hydrates/National Engineering Laboratory for Pipeline Safety China University of PetroleumBeijing102249China PipeChina West East Pipeline Company Shanghai200122China Key Lab of Deepwater Engineering CNOOC Research InstituteBeijing100028China

Understanding the kinetics and viscosity of hydrate slurry in gas-water-sand system is of great significance for the high-efficiency and high-safety development of natural gas *** effect of micronsized sands with various concentrations and particle sizes on the hydrate formation,dissociation,and viscosity in gas-water-sand system are investigated in this *** experimental results show that the hydrate induction time in the sandy system is slightly prolonged compared to the pure gas-water system,and the inhibition effect first strengthens and then weakens as the sand concentration increases from0 wt%to 5 wt%.Besides,the difference of hydrate formation amount in various cases is not *** concentration and particle size of sand have little effect on the kinetics of hydrate *** promoting and inhibiting effects on hydrate formation have been found in the sandy multiphase *** the viscosity characteristics,there are three variations of hydrate slurry viscosity during the formation process:Steep drop type,S-type and Fluctuation ***,appropriate sand size is helpful to reduce the randomness of slurry viscosity ***,even at the same hydrate volume fraction,the slurry viscosity in the formation process is significantly higher than that in dissociation process,which needs further *** work provides further insights of hydrate formation,dissociation,and viscosity in gas-water-sand system,which is of great significance for safe and economic development of natural gas hydrates.

关键词： Hydrate slurry Micron-sized sands Hydrate formation Hydrate dissociation Viscosity characteristics

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A STREAMLINE-BASED PREDICTIVE MODEL FOR ENHANCED-OIL-RECOVERY POTENTIALITY

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Journal of Hydrodynamics 2008年第3期20卷 314-322页

作者： HOU Jian ZHANG shun-kang DU Qing-jun LI Yu-bin College of Petroleum Engineering China University of Petroleum （East China） Dongying 257061 China Chemical and Petroleum Department University of Calgary Calgary T2N 1N4 Canada

A pseudo-three-dimensional model of potentiality prediction is proposed for enhanced oil recovery, based on the streamline method described in this article. The potential distribution of the flow through a porous medium under a complicated boundary condition is solved with the boundary element method. Furthermore, the method for tracing streamlines between injection wells and producing wells is presented. Based on the results, a numerical solution can be obtained by solving the seepage problem of the stream-tube with consideration of different methods of Enhanced Oil Recovery（EOR）. The advantage of the method given in this article is that it can obtain dynamic calculation with different well patterns of any shape by easily considering different physicochemical phenomena having less calculation time and good stability. Based on the uniform theory basis-streamline method, different models, including CO2 miscible flooding, polymer flooding, alkaline/surfactant/polymer flooding and microbial flooding, are established in this article.

关键词： boundary element method streamline method Enhanced Oil Recovery(EOR) CO2 miscible flooding chemical flooding microbial flooding

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冷却孔附近三维流动的结构

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工程热物理学报 2006年第5期27卷 754-756页

作者：康顺华北电力大学电站设备状态监测与控制教育部重点实验室北京102206

本文简略综述了横流中射流研究的局部结构,并且采用数值模拟的方法,研究在给定横向流速和不同吹风比(0．5、1．0和1．5)条件下,圆形垂直射流孔附近区域三维定常流动的流场,以揭示局部流场的复杂涡系结构和形成机理。

关键词：气膜冷却横流中的射流旋涡 CFD

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Thorough liberation： A feminist analysis of How lfinally lost my heart

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Sino-US English Teaching 2008年第4期5卷 68-71页

作者： kang shun-li School of Foreign Languages Shanghai University Shanghai 200444 China

How lfinally lost my heart is a short story written by Doris Lessing, the winner of the 2007 Nobel Prize in Literature. This paper is intended to analyze this short story from the feminist perspective, and show the ex... 详细信息

关键词： How l finally lost my heart feminism patriarchy liberation

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Predicting disease progression in cirrhotic patients after transjugular intrahepatic portosystemic shunt implantation:A sexstratified analysis

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World Journal of Gastroenterology 2023年第42期29卷 5768-5780页

作者： Qian Zhang Li Long Hong-Lin Zhu Hong Peng Xin-Hua Luo kang-shun Zhu Rong-Pin Wang Department of Radiology Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina The Second Affiliated Hospital of Guangzhou Medical University Guangzhou 510260Guangdong ProvinceChina Department of Infectious Diseases Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina Department of Interventional Radiology Guizhou Provincial People’s HospitalGuiyang 550002Guizhou ProvinceChina Department of Interventional Radiology The Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhou 510260Guangdong ProvinceChina

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)has been extensively used to treat portal hypertension-associated complications,including *** prediction of post-TIPS prognosis is important for cirrhotic patients,as more aggressive liver transplantation is needed when the post-TIPS prognosis is *** To construct a nutrition-based model that could predict the disease progression of cirrhotic patients after TIPS implantation in a sex-dependent *** This study retrospectively recruited cirrhotic patients undergoing TIPS implantation for *** quality was assessed by measuring the skeletal muscle index(SMI)by computed *** Cox proportional hazard models were utilized to determine the association between SMI and disease progression in cirrhotic patients after TIPS *** This study eventually included 186 cirrhotic patients receiving TIPS who were followed up for 30.5±18.8 *** male patients,the 30-mo survival rate was significantly lower and the probability of progressive events was higher(3.257-fold)in the low-level SMI group than in the high-level SMI *** to the multivariate Cox analysis of male patients,SMI<32.8 was an independent risk factor for long-term adverse outcomes after TIPS implantation.A model was constructed,which involved creatinine,plasma ammonia,SMI,and acute-on-chronic liver failure and hepatic encephalopathy occurring within half a year after *** model had an area under the receiver operating characteristic curve of 0.852,sensitivity of 0.926,and specificity of *** to the results of the DeLong test,this model outperformed other models(Child-Turcotte-Pugh,Model for End-Stage Liver Disease,and Freiburg index of post-TIPS survival)(P<0.05).CONCLUSION SMI is strongly associated with poor long-term outcomes in male patients with cirrhosis who underwent TIPS implantation.

关键词： Transjugular intrahepatic portosystemic shunt Skeletal muscle index Nutrition Cirrhosis Sex stratified Prognosis

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