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Stepped-up development of accelerator mass spectrometry method for the detection of ^(60)Fe with the HI-13 tandem accelerator

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Nuclear Science and Techniques 2024年第4期35卷 136-143页

作者： Yang zhang Sheng-Quan Yan Ming He Qing-zhang Zhao Wen-Hui zhang Chao-Xin Kan jian-Ming Zhou kang-Ning Li xiao-Fei Wang jian-Cheng Liu Zhao-Hua Peng Zhuo Liang Ai-Ling Li jian Zheng Qi-Wen Fan Yun-Ju Li You-Bao Wang Zhi-Hong Li Yang-Ping Shen Ding Nan Wei Nan Yu-Qiang zhang Jia-Ying-Hao Li jun-Wen Tian jiang-Lin Hou Chang-Xin Guo Zhi-Cheng zhang Ming-Hao Zhu Yu-Wen Chen Yu-Chen jiang Tao Tian Jin-Long Ma Yi-Hui Liu Jing-Yu Dong Run-Long Liu Mei-Yue-Nan Ma Yong-Shou Chen Wei-Ping Liu Bing Guo China Institute of Atomic Energy P.O.Box 275(10)Beijing 102413China College of Science Southern University of Science and TechnologyShenzhen 518055China School of Physics Xi’an Jiaotong UniversityXi’an 710049China

The Moon provides a unique environment for investigating nearby astrophysical events such as *** samples retain valuable information from these events,via detectable long-lived“fingerprint”radionuclides such as^(60)*** this work,we stepped up the development of an accelerator mass spectrometry(AMS)method for detecting^(60)Fe using the HI-13tandem accelerator at the China Institute of Atomic Energy(CIAE).Since interferences could not be sufficiently removed solely with the existing magnetic systems of the tandem accelerator and the following Q3D magnetic spectrograph,a Wien filter with a maximum voltage of±60 kV and a maximum magnetic field of 0.3 T was installed after the accelerator magnetic systems to lower the detection background for the low abundance nuclide^(60)Fe.A 1μm thick Si_(3)N_(4) foil was installed in front of the Q3D as an energy *** particle detection,a multi-anode gas ionization chamber was mounted at the center of the focal plane of the ***,an^(60)Fe sample with an abundance of 1.125×10^(-10)was used to test the new AMS *** results indicate that^(60)Fe can be clearly distinguished from the isobar^(60)*** sensitivity was assessed to be better than 4.3×10^(-14)based on blank sample measurements lasting 5.8 h,and the sensitivity could,in principle,be expected to be approximately 2.5×10^(-15)when the data were accumulated for 100 h,which is feasible for future lunar sample measurements because the main contaminants were sufficiently separated.

关键词： Accelerator mass spectrometry Wien filter Isobar separation Supernovae Chang'e-5 lunar samples

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10B-doped MCP detector developed for neutron resonance imaging at Back-n white neutron source

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Nuclear Science and Techniques 2024年第8期35卷 58-68页

作者： Qiang Li Li‑Jiao Wang Jing‑Yu Tang xiang‑Biao Qiu Zhen Chen Mao‑Yuan Zhao Chang‑jun Ning Kai Pan Wei Xu Tao Li Su‑Peng Lu Han Yi rui‑rui Fan Chang‑Qing Feng Rong zhang xiao‑Yang Sun Qi An Hao‑Fan Bai jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping Chen Yong‑Hao Chen Zeng‑Qi Cui An‑Chuan Fan Fan‑Zhen Feng Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei jiang Zhi‑Jie jiang Zheng‑Yao Jin Ling kang Bo Li Gong Li xiao Li Yang Li Jie Liu Rong Liu Shu‑Bin Liu Yi‑Na Liu Guang‑Yuan Luan Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song kang Sun Zhi‑Xin Tan Sheng‑Da Tang Jin‑Cheng Wang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑Guang Wu Xuan Wu Cong xia Yong‑Ji Yu Guo‑Hui zhang Hang‑Chang zhang Lin‑Hao zhang Qi‑Wei zhang xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑Yong zhang Zhi‑Hao Zhou Ke‑jun Zhu Chong Zou Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China North Night Vision Science and Technology(Nanjing)Research Institute Co.Ltd Nanjing 211106China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Modern Physics Fudan UniversityShanghai 200433China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China China Academy of Engineering Physics Institute of Nuclear Physics and ChemistryMianyang 621900China USTC archaeometry lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China China Shipbuilding Trading Co. LtdBeijing 100044China

Neutron resonance imaging(NRI)has recently emerged as an appealing technique for neutron *** complexity surpasses that of conventional transmission imaging,as it requires a high demand for both a neutron source and ***,the progression of NRI technology has been sluggish since its inception in the 1980s,particularly considering the limited studies analyzing the neutron energy range above *** white neutron source(Back-n)at the China Spallation Neutron Source(CSNS)provides favorable beam conditions for the development of the NRI technique over a wide neutron energy range from eV to ***-sensitive microchannel plates(MCP)have emerged as a cutting-edge tool in the field of neutron detection owing to their high temporal and spatial resolutions,high detection efficiency,and low *** this study,we report the development of a 10B-doped MCP detector,along with its associated electronics,data processing system,and NRI experiments at the *** heavy elements such as gold,silver,tungsten,and indium can be easily identified in the transmission images by their characteristic resonance peaks in the 1–100 eV energy range;the more difficult medium-weight elements such as iron,copper,and aluminum with resonance peaks in the 1–100 keV energy range can also be *** particular,results in the neutron energy range of dozens of keV(Aluminum)are reported here for the first time.

关键词： Neutron resonance imaging 10B doped MCP detector White neutron source Sample nuclide identification

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Application of alginate in inflammatory bowel disease

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Biomedical Engineering Communications 2024年第2期3卷 10-16页

作者： rui-Xue kang Ying Zhuang Ming-Jie Liu Qi Han Wei-Li zhang Wei-Yu Fan Xue Gao Jia-Zheng Zhou jian-Bin zhang Collage of Pharmacy Dalian Medical UniversityDalian 116044China Laboratory Animal Center Dalian Medical UniversityDalian 116044China

Inflammatory bowel disease(IBD)represents a chronic inflammatory condition profoundly impacting the gastrointestinal *** prevalence has markedly risen in both developed and developing nations over recent *** the absence of definitive etiological elucidation,therapeutic strategies predominantly revolve around pharmacological interventions aimed at symptom ***(AG)is a polysaccharide of marine origin that has garnered significant attention due to its inherent biocompatibility,pH sensitivity,and *** exploration within drug delivery systems for IBD treatment stems from its natural sourcing,non-cytotoxic nature,and economic ***,AG demonstrates facile interpolymeric cross-linking,facilitating the formation of a cohesive network conducive to sustained drug release ***-based carrier systems for sustained drug release,and targeted drug delivery have been widely *** article reviews the pathogenesis of IBD and the current drugs,AG-based drug delivery systems and their properties in alleviating *** prospect of further development of AG in the field of biopharmaceutical and drug delivery is prospected.

关键词： alginate inflammatory bowel disease drug delivery

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废旧三元锂电池石墨负极电化学除杂及其性能研究

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新型炭材料（中英文） 2024年第3期39卷 573-582页

作者：张锐田勇张维丽宋佳音闵杰庞博陈建军深圳清华大学研究院广东深圳518057 深圳清研锂业科技有限公司广东深圳518057

随着新能源汽车迅速发展,动力锂离子电池应用越来越广泛,大量锂电池也迎来退役高峰期,废旧锂电池的回收综合利用引起各国高度关注。废旧锂电池石墨负极层状结构基本未变化,因此回收时不需高温石墨化,只需关注其内部杂质的去除。本文将... 详细信息

随着新能源汽车迅速发展,动力锂离子电池应用越来越广泛,大量锂电池也迎来退役高峰期,废旧锂电池的回收综合利用引起各国高度关注。废旧锂电池石墨负极层状结构基本未变化,因此回收时不需高温石墨化,只需关注其内部杂质的去除。本文将废旧石墨负极进行热处理、超声分离和酸浸处理后,创新性地采用电化学处理将内部金属杂质深度去除。对比不同回收阶段的石墨,发现石墨中有机杂质的存在会严重影响各项电化学性能,微量Cu、Fe等无机杂质的存在对初始放电比容量影响不大,但会降低石墨的循环稳定性。最终回收的石墨内部主要金属杂质含量低于20 mg/kg,在0.1 C倍率下放电比容量达到358.7 mAh/g,循环150圈后容量保持率为95.85%。对比已报道的废旧石墨回收方法,此方法可深度去除石墨负极内部杂质,解决了目前酸碱用量大、除杂不彻底、能耗高等问题,回收再生石墨负极电化学性能较好,为废旧锂电池石墨负极提供了一条新的回收再生路径。

关键词：电池回收废旧石墨电化学除杂电化学性能杂质影响

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人造黑色素染发材料

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高分子学报 2024年第2期55卷 192-201页

作者：杨磊张小康张键华胡俊飞张婷顾志鹏李乙文四川大学高分子科学与工程学院高分子材料工程国家重点实验室成都610065

传统仿生人造黑色素聚多巴胺(PDA)染发过程中涉及的过强碱性会使毛发粗糙影响发质,大量的金属离子则存在安全性问题.本工作利用黑色素单体5,6-二羟基吲哚(DHI)能够在温和条件下仅通过空气氧化发生快速聚合的特点,报道了一种通过温和条... 详细信息

传统仿生人造黑色素聚多巴胺(PDA)染发过程中涉及的过强碱性会使毛发粗糙影响发质,大量的金属离子则存在安全性问题.本工作利用黑色素单体5,6-二羟基吲哚(DHI)能够在温和条件下仅通过空气氧化发生快速聚合的特点,报道了一种通过温和条件在头发表面和内部原位聚合的人造黑色素染发材料.染发色度值L=21,与自然黑发基本一致,洗涤30次后L=25,耐洗涤性良好,染色后头发拉伸强度189 MPa,断裂伸长率51%,相比染色前发质有所改善.研究结果表明,此类染发剂染发条件温和(空气氧化),色度自然,固色持久,有助于改善发质,生物安全性良好,为开发新一代染发剂提供了创新的设计策略和可靠的工具平台.

关键词：人造黑色素聚二羟基吲哚染发剂仿生材料

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Luspatercept enhances hemoglobin levels in a Chinese boy with congenital sideroblastic anemia:A case report

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World Journal of Clinical Cases 2024年第19期12卷 3978-3984页

作者： Yuan Li Lei Ye kang Zhou Hui-Hui Fan jian-Ping Li You-Zhen Xiong Yang Yang Guang-Xin Peng Wen-rui Yang Xin Zhao Li-Ping Jing Li zhang Feng-Kui zhang Anemia Therapeutic Center Institute of Hematology and Blood Diseases HospitalChinese Academy of Medical SciencePeking Union Medical CollegeTianjin 300020China

BACKGROUND Congenital sideroblastic anemia(CSA)is a rare and heterogeneous group of genetic *** treatment include pyridoxine(vitamin B6)and allogeneic hematopoietic stem cell transplantation(allo-HSCT),and can alleviate anemia in the majority of ***,some CSA cases remain unresponsive to pyridoxine or are unable to undergo *** management approaches is necessary to be *** explore the response of luspatercept in treating congenital sideroblastic *** SUMMARY We share our experience in luspatercept in a 4-year-old male patient with *** was administered subcutaneously at doses of 1.0 mg/kg/dose to 1.25 mg/kg/dose every 3 wk,three consecutive doses,evaluating the hematological *** leading to a significant improvement in the patient's *** median hemoglobin during the overall treatment with three doses of luspatercept was 90(75-101)g/L,the median absolute reticulocyte count was 0.0593(0.0277-0.1030)×10^(12)/L,the median serum ferritin was 304.3(234.4-399)ng/mL,and the median lifespan of mature red blood cells was 80(57-92)***,no adverse reactions,such as headaches,dizziness,vomiting,joint pain,or back pain,were observed during the treatment *** We believe that luspatercept might emerge as a viable therapeutic option for the maintenance treatment of CSA or as a bridging treatment option before hematopoietic stem cell transplantation.

关键词： Anemia Sideroblastic anemia Luspatercept Congenital Lifespan of mature red blood cells Microcytic anemia Case report

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Study of the response of 10B-doped MCP to wide-energy range neutrons from eV to MeV

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Nuclear Science and Techniques 2024年第8期35卷 132-141页

作者： Qiang Li Li‑Jiao Wang xiang‑Biao Qiu Jing‑Wen Li Wei Xu Tao Li Ze‑Bin Lin Chang‑jun Ning Yong‑Hao Chen rui‑rui Fan kang Sun Jing‑Yu Tang Rong zhang Han‑Tao Jing Bo Mei Qi An Hao‑Fan Bai jiang‑Bo Bai Jie Bao Ping Cao Qi‑Ping Chen Zhen Chen Zeng‑Qi Cui An‑Chuan Fan Chang‑Qing Feng Fan‑Zhen Feng Ke‑Qing Gao Min‑Hao Gu Chang‑Cai Han Zi‑Jie Han Guo‑Zhu He Yong‑Cheng He Yang Hong Yi‑Wei Hu Han‑Xiong Huang Wei‑Hua Jia Hao‑Yu jiang Wei jiang Zhi‑Jie jiang Zheng‑Yao Jin Ling kang Bo Li Chao Li Gong Li Jia‑Wen Li xiao Li Yang Li Jie Liu Rong Liu Shu‑Bin Liu Guang‑Yuan Luan Bin‑Bin Qi Jie Ren Zhi‑Zhou Ren Xi‑Chao Ruan Zhao‑Hui Song Zhi‑Xin Tan Sheng‑Da Tang Peng‑Cheng Wang Zhao‑Hui Wang Zhong‑Wei Wen xiao‑Guang Wu Xuan Wu Li‑Kun Xie Yi‑Wei Yang Han Yi Yong‑Ji Yu Guo‑Hui zhang Lin‑Hao zhang Mo‑Han zhang Qi‑Wei zhang xian‑Peng zhang Yu‑Liang zhang Yue zhang Zhi‑Yong zhang Mao‑Yuan Zhao Lu‑Ping Zhou Zhi‑Hao Zhou Ke‑jun Zhu Institute of High Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Dongguan Songshan Lake Future School Dongguan 523808China North Night Vision Science&Technology(Nanjing)Research Institute Co.Ltd. Nanjing 211106China Sino‑French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230027China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China USTC Archaeometry Lab University of Science and Technology of ChinaHefei 230026China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Neutron-sensitive microchannel plates(nMCPs)have applications in neutron detection,including energy spectrum measurements,neutron-induced cross sections,and neutron imaging.10B-doped MCPs(B-MCPs)have attracted significant attention owing to their potential for exhibiting a high neutron detection efficiency over a large neutron energy *** spatial and temporal resolutions are useful for neutron energy-resolved ***,their practical applications still face many technical *** this study,a B-MCP with 10 mol%10B was tested for its response to wide-energy neutrons from eV to MeV at the Back-n white neutron source at the China Spallation Neutron *** neutron detection efficiency was calibrated at 1 eV,which is approximately 300 times that of an ordinary MCP and indicates the success of 10 B *** factors that caused the reduction in the detection efficiency were simulated and *** neutron energy spectrum obtained using B-MCP was compared with that obtained by other measurement methods,and showed very good consistency for neutron energies below tens of *** response is more complicated at higher neutron energy,at which point the elastic and nonelastic reactions of all nuclides of B-MCP gradually become *** is beneficial for the detection of neutrons,as it compensates for the detection efficiency of B-MCP for high-energy neutrons.

关键词： Neutron radiation image 10B-doped MCP Neutron response Wide-energy range neutrons

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Nondestructive technique for identifying nuclides using neutron resonance transmission analysis at CSNS Back-n

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Nuclear Science and Techniques 2024年第1期35卷 178-187页

作者： Sheng-Da Tang Yong-Hao Chen Jing-Yu Tang rui-rui Fan Qiang Li Gong Li Dong Liu Zheng-Yao Jin Xing-Zhu Cui Tian-xiang Chen Yi-Wei Yang Rong Liu Han Yi Yang Li Zhen Yang Qi An Hao-Fan Bai jiang-Bo Bai Jie Bao Ping Cao Qi-Ping Chen Zhen Chen Zeng-Qi Cui An-Chuan Fan Chang-Qing Feng Fan-Zhen Feng Ke-Qing Gao Min-Hao Gu Chang-Cai Han Zi-Jie Han Guo-Zhu He Yong-Cheng He Yang Hong Yi-Wei Hu Han-Xiong Huang Wei-Hua Jia Hao-yu jiang Wei jiang Zhi-jie jiang Ling kang Bo Li Chao Li Jia-Wen Li xiao Li Jie Liu Shu-Bin Liu Guang-Yuan Luan Chang-jun Ning Bin-Bin Qi Jie Ren Zhi-Zhou Ren Xi-Chao Ruan Zhao-Hui Song kang Sun Zhi-Xin Tan Li-Jiao Wang Peng-Cheng Wang Zhao-Hui Wang Zhong-Wei Wen xiao-Guang Wu Xuan Wu Li-Kun Xie Yong-Ji Yu Guo-Hui zhang Lin-Hao zhang Mo-Han zhang Qi-Wei zhang xian-Peng zhang Yu-Liang zhang Yue zhang Zhi-Yong zhang Mao-Yuan Zhao Lu-Ping Zhou Zhi-Hao Zhou Ke-jun Zhu Sino-French Institute of Nuclear Engineering and Technology Sun Yat-sen UniversityZhuhai 519082China Institute of High-Energy Physics Chinese Academy of Sciences(CAS)Beijing 100049China Spallation Neutron Source Science Center Dongguan 523803China School of Nuclear Science and Technology University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Particle Detection and Electronics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China USTC Archaeometry Laboratory University of Science and Technology of ChinaHefei 230026China Institute of Nuclear Physics and Chemistry China Academy of Engineering PhysicsMianyang 621900China Department of Modern Physics University of Science and Technology of ChinaHefei 230026China State Key Laboratory of Nuclear Physics and Technology School of PhysicsPeking UniversityBeijing 100871China Key Laboratory of Nuclear Data China Institute of Atomic EnergyBeijing 102413China Northwest Institute of Nuclear Technology Xi’an 710024China University of Chinese Academy of Sciences Beijing 100049China

Nondestructive and noninvasive neutron assays are essential applications of neutron *** resonance transmission analysis(NRTA)is a powerful nondestructive method for investigating the elemental composition of an *** back-streaming neutron line(Back-n)is a newly built time-of-flight facility at the China Spallation Neutron Source(CSNS)that provides neutrons in the eV to 300 MeV range.A feasibility study of the NRTA method for nuclide identification was conducted at the CSNS Back-n via two test *** results demonstrate that it is feasible to identify different elements and isotopes in samples using the NRTA method at *** study reveals its potential future applications.

关键词： CSNS White neutron beam NRTA Nuclide identification Nondestructive method

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超声造影评估无症状性ICA重度狭窄患者CAS术后脑灌注改变的研究

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中国临床医学影像杂志 2024年第8期35卷 533-536页

作者：程令刚康睿君何文张巍张琳首都医科大学附属北京天坛医院超声科北京100160

目的:应用超声造影评估无症状性颈内动脉(ICA)重度狭窄患者行颈动脉支架置入术(CAS)后的脑灌注改变的价值。方法:选取2020年7月-2022年12月我院行CAS术的单侧ICA重度狭窄患者18例,男14例,女4例,平均年龄(62.6±7.3)岁。患者无临床症状... 详细信息

目的:应用超声造影评估无症状性颈内动脉(ICA)重度狭窄患者行颈动脉支架置入术(CAS)后的脑灌注改变的价值。方法:选取2020年7月-2022年12月我院行CAS术的单侧ICA重度狭窄患者18例,男14例,女4例,平均年龄(62.6±7.3)岁。患者无临床症状或仅表现为轻度头痛、头晕。分别于CAS术前、术后12 h内行双侧经颅超声造影检查,选取基底节区作为感兴趣区(ROI)进行时间-强度曲线分析,测量参数为达峰时间(TTP),平均通过时间(MTT),上升斜率(WIS),峰值强度(PI),曲线下面积(AUC),计算患侧与健侧参数的相对值rTTP,rMTT,rWIS,rPI,rAUC,及CAS术后改变量ΔrTTP,ΔrMTT,Δr WIS,Δr PI,ΔrAUC。比较CAS术前、术后参数绝对值与相对值,并对CAS术前相对值与术后改变量的相关性进行分析。结果:CAS术前,患侧TTP(22.17±3.34) s,MTT (33.73±5.88) s均较健侧延长,WIS (1.75±0.68) dB/s低于健侧(P<0.05),而PI,AUC双侧比较无统计学差异;CAS术后,患侧参数绝对值仅WIS (2.14±0.69) dB/s较术前增高(P<0.05);相对值rTTP (1.02±0.08),r MTT(0.96±0.10)低于术前,rWIS (1.02±0.17)较术前增高(P<0.05);CAS术前相对值rTTP,rMTT,rWIS分别与术后改变量ΔrTTP,Δr MTT,ΔrWIS存在负相关关系(r值分别为-0.592,-0.754及-0.730)。结论:超声造影可评估无症状性ICA重度狭窄患者CAS术后脑灌注的改变,术后双侧灌注差异性降低,且患侧术前脑灌注受损程度越重,术后改善越明显。

关键词：颈动脉狭窄超声检查,多普勒,彩色

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DNS信道传输加密技术:现状、趋势和挑战

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软件学报 2024年第1期35卷 309-332页

作者：张曼姚健康李洪涛董科军延志伟中国互联网络信息中心北京100190

DNS作为重要的互联网基础设施,其明文传输的特点带来很多隐私安全风险.DoH、DoT、DoQ等DNS信道传输加密技术致力于防止DNS数据被泄露或篡改,并保证DNS消息来源的可靠性.首先从DNS消息格式、数据存储和管理、系统架构和部署等6个方面分... 详细信息

DNS作为重要的互联网基础设施,其明文传输的特点带来很多隐私安全风险.DoH、DoT、DoQ等DNS信道传输加密技术致力于防止DNS数据被泄露或篡改,并保证DNS消息来源的可靠性.首先从DNS消息格式、数据存储和管理、系统架构和部署等6个方面分析明文DNS存在的隐私安全问题,并对已有的相关技术和协议进行总结.其次分析DNS信道传输加密技术的实现原理及应用现状,进而基于多角度评测指标对各加密协议在不同网络条件下的性能表现进行讨论.同时通过填充机制的局限性、加密流量识别和基于指纹的加密活动分析等方向探讨DNS信道传输加密技术的隐私保护效果.此外从部署规范、恶意流量对加密技术的利用和攻击、隐私和网络安全管理之间的矛盾,以及加密后影响隐私安全的其他因素等方面总结DNS信道传输加密技术存在的问题、挑战和相关解决方案.最后总结加密DNS服务的发现、递归解析器到权威服务器之间的加密、服务器端的隐私保护、基于HTTP/3的DNS等后续需要着重关注的研究方向.

关键词：隐私安全 QUIC TLS 1.3 DoH DoT DoQ

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