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Waveguide electro-optic modulators based on self-assembled material systems

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光学精密工程 2005年第5期13卷 554-560页

作者： LIU Zhi-fu MA Jing SUN De-gui XU Guo-yang HO Seng-Tiong Zhu Pei wang kang hu Antonio Facchetti Tobin J. Marks Department of Electrical and Computer Engineering Northwestern University Evanston IL 60208 USA Department of Chemistry and Materials Research Center Northwestern University Evanston IL 60208 USA

Fabrication and characterization of electro-optic modulators based on the novel organic electro-optic materials composed of self-assembled superlattices (SAS) were presented, both wet-dipping self-assembly and vapor phase deposition approaches were discussed. Prototype waveguide electro-optic modulators were fabricated using SAS films integrated with low-loss polymeric materials functioning as partial guiding and cladding *** electro-optic thin film materials including DTPT and PEPCOOH grown from the vapor phase were used for fabrication and test of electro-optic prototype modulators. Finally,the EO coefficient of tens of pm/V was obtained,which can sufficiently support high-speed and small size EO modulators.

关键词：电子波导光电子调节器 SAS 薄膜

Association between the frontoparietal network,clinical symptoms and treatment response in individuals with untreated anorexia nervosa

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General Psychiatry 2024年第3期37卷 364-374页

作者： Qianqian He hui Zheng Jialin Zhang Ling Yue Qing kang Cheng Lian Lei Guo Yan Chen Yanran hu Yuping Wang Sufang Peng Zhen Wang Qiang Liu Jue Chen Department of Clinical Psychology Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Clinical Psychology Shanghai Pudong New Area Mental Health CenterTongji University School of MedicineShanghaiChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research Bejing Normal UniversityBeijingChina

Background Anorexia nervosa(AN)has been characterised as a psychiatric disorder associated with increased ***,it remains difficult to predict treatment response in patients with *** cognitive abilities are known to be resistant to *** has been established that the frontoparietal control network(FPCN)is the direct counterpart of the executive control ***,the resting-state brain activity of the FPCN may serve as a biomarker to predict treatment response in *** The study aimed to investigate the association between resting-state functional connectivity(RSFC)of the FPCN,clinical symptoms and treatment response in patients with *** In this case-control study,79 female patients with AN and no prior treatment from the Shanghai Mental Health Center and 40 matched healthy controls(HCs)were recruited from January 2015 to March *** participants completed the Questionnaire Versionof the Eating Disorder Examination(version 6.0)to assess the severity of their eating disorder ***,RSFC data were obtained from all participants at baseline by functional magnetic resonance *** with AN underwent routine outpatient treatment at the 4th and 12th week,during which time their clinical symptoms were evaluated using the same measures as at *** Among the 79 patients,40 completed the 4-week follow-up and 35 completed the 12-week *** RSFC from the right posterior parietal cortex(PPC)and dorsolateral prefrontal cortex(diPFC)increased in 79 patients with AN vs 40 HCs after controlling for depression and anxiety *** multiple linear regression,the RSFC of the PPC to the inferior frontal gyrus was found to be a significant factor for self-reported eating disorder symptoms at baseline and the treatment response to cognitive preoccupations about eating and body image,after controlling for age,age of onset and body mass *** RSFC in the dIPFC to the middle temporal gyrus and the

关键词： symptoms routine prevention

我国化妆品原料安全信息库的建立及其应用展望

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日用化学工业（中英文） 2022年第11期52卷 1221-1228页

作者：苏哲胡康王钢力路勇中国食品药品检定研究院北京100050

在新修订的《化妆品监督管理条例》背景下,国家药监局构建了全新的化妆品法规和技术体系,加强了化妆品原料管理和安全评估,并提出化妆品原料安全信息报送相关要求。中检院结合法规要求和监管实际需求,围绕化妆品原料的精细化管理开展一... 详细信息

在新修订的《化妆品监督管理条例》背景下,国家药监局构建了全新的化妆品法规和技术体系,加强了化妆品原料管理和安全评估,并提出化妆品原料安全信息报送相关要求。中检院结合法规要求和监管实际需求,围绕化妆品原料的精细化管理开展一系列相关研究,包括原料分类和关键特征、原料基本信息、原料鉴别和特征性指标、风险信息和控制指标、安全信息使用等,并据此建设“化妆品原料安全信息登记平台”,用于化妆品原料安全信息的规范化填报和管理。通过对化妆品原料安全信息的收集、利用和分析,同时对化妆品法规标准相关数据库不断研究整合,将在我国逐步构建起科学高效的“化妆品原料安全信息库”,在化妆品技术监管工作中提供有力的大数据支撑,不断提高我国的化妆品监管和安全性评价水平。

关键词：化妆品原料安全信息数据库安全评估监管

Postnatal development of rat retina:a continuous observation and comparison between the organotypic retinal explant model and in vivo development

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Neural Regeneration Research 2025年第3期20卷 900-912页

作者： Baoqi hu Rui Wang Hanyue Zhang Xiou Wang Sijia Zhou Bo Ma Yan Luan Xin Wang Xinlin Chen Zhichao Zhang Qianyan kang Department of Ophthalmology The First Affiliated Hospital of Xi’an Jiaotong UniversityXi’anShaanxi ProvinceChina Department of Ophthalmology The First Affiliated Hospital of Northwest UniversityXi’anShaanxi ProvinceChina Institute of Neurobiology Xi’an Jiaotong University Health Science CenterXi’anShaanxi ProvinceChina

The organotypic retinal explant culture has been established for more than a decade and offers a range of unique advantages compared with in vivo experiments and cell ***,the lack of systematic and continuous comparison between in vivo retinal development and the organotypic retinal explant culture makes this model controversial in postnatal retinal development ***,we aimed to verify the feasibility of using this model for postnatal retinal development studies by comparing it with the in vivo *** this study,we showed that postnatal retinal explants undergo normal development,and exhibit a consistent structure and timeline with retinas in ***,we used SOX2 and PAX6 immunostaining to identify retinal progenitor *** then examined cell proliferation and migration by immunostaining with Ki-67 and doublecortin,***-67-and doublecortin-positive cells decreased in both in vivo and explants during postnatal retinogenesis,and exhibited a high degree of similarity in abundance and distribution between ***,we used Ceh-10 homeodomain-containing homolog,glutamate-ammonia ligase(glutamine synthetase),neuronal nuclei,and ionized calcium-binding adapter molecule 1 immunostaining to examine the emergence of bipolar cells,Müller glia,mature neurons,and microglia,*** timing and spatial patterns of the emergence of these cell types were remarkably consistent between in vivo and explant *** study showed that the organotypic retinal explant culture model had a high degree of consistency with the progression of in vivo early postnatal retina *** findings confirm the accuracy and credibility of this model and support its use for long-term,systematic,and continuous observation.

关键词： bipolar cells differentiation in vivo microglia Müller glia organotypic retinal explant culture postnatal retina development proliferation retinal progenitor cells

Preoperative serum cortisone levels are associated with cognition in preschool‑aged children with tetralogy of Fallot after corrective surgery:new evidence from human populations and mice

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World Journal of Pediatrics 2024年第2期20卷 173-184页

作者： Si-Yu Ma Yu-Ting Liu Yue-Shuang Cun Qiang Wang Ming-Cui Fu Ke-De Wu Xin-Yu Cai Shu-Ting Cheng Nishant Patel Min Da Liang hu Zhuoga Deqin Xue-Jun kang Ming Yang Xu-Ming Mo Department of Cardiothoracic Surgery Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Department of Radiology Children’s Hospital of Nanjing Medical University72 Guangzhou RoadNanjing 210008China Key Laboratory of Child Development and Learning Science Research Center For Learning ScienceSchool of Biological Sciences&Medical EngineeringMinistry of EducationSoutheast UniversityNanjing 210096China Medical School of Nanjing University Nanjing 210093China

Background Tetralogy of Fallot(TOF)is the most common cyanotic congenital heart *** with TOF would be confronted with neurological impairment across their *** study aimed to identify the risk factors for cerebral morphology changes and cognition in postoperative preschool-aged children with *** We used mass spectrometry(MS)technology to assess the levels of serum metabolites,Wechsler preschool and primary scale of intelligence-Fourth edition(WPPSI-Ⅳ)index scores to evaluate neurodevelopmental levels and multimodal magnetic resonance imaging(MRI)to detect cortical morphological *** Multiple linear regression showed that preoperative levels of serum cortisone were positively correlated with the gyrification index of the left inferior parietal gyrus in children with TOF and negatively related to their lower visual spaces index and nonverbal ***,preoperative SpO_(2) was negatively correlated with levels of serum cortisone after adjusting for all ***,after intervening levels of cortisone in chronic hypoxic model mice,total brain volumes were reduced at both postnatal(P)11.5 and P30 *** Our results suggest that preoperative serum cortisone levels could be used as a biomarker of neurodevelopmental impairment in children with *** study findings emphasized that preoperative levels of cortisone could influence cerebral development and cognition abilities in children with TOF.

关键词： Cognition Cortisone MRI Neurodevelopment Tetralogy of Fallot

基于自适应卡尔曼滤波残差分析的雷击故障定位

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电力系统保护与控制 2020年第23期48卷 30-39页

作者：席燕辉胡康王康长沙理工大学电气与信息工程学院湖南长沙410114

雷击是引起电力传输和配电系统中瞬态、故障和停电的重要原因。为提高在含噪环境下雷击故障点检测的准确性与可靠性,提出了一种基于最大似然(KF-ML)卡尔曼滤波残差分析的雷击故障定位方法。首先通过比较短路故障电流与雷击故障电流之间... 详细信息

雷击是引起电力传输和配电系统中瞬态、故障和停电的重要原因。为提高在含噪环境下雷击故障点检测的准确性与可靠性,提出了一种基于最大似然(KF-ML)卡尔曼滤波残差分析的雷击故障定位方法。首先通过比较短路故障电流与雷击故障电流之间的瞬态特性差异来区分出短路故障和雷击故障。当行波波头到达时,估计的滤波残差呈现出尖锐的奇异性。通过比较初始行波到达两端的时间,确定雷击侧和故障侧,进一步根据双端测距法可以计算出雷击点距离。同时通过初始雷击行波到达故障侧的时间和来自故障点的反射波时间来获得故障点距离。通过模拟雷电流的仿真分析表明了该方法能有效检测到行波波头,并将其应用在不同条件下的雷击定位和故障定位测试中,且灵敏度高。

关键词：瞬态电流卡尔曼滤波最大似然滤波残差奇异性

Synthesis,characterization and catalytic performance of Mo based metal-organic frameworks in the epoxidation of propylene by cumene hydroperoxide

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Chinese Chemical Letters 2017年第5期28卷 1057-1061页

作者： Xiao-Lei Ni Jing Liu Ying-Ya Liu Karen Leus Hannes Depauw An-Jie Wang Pascal Van Der Voort Jian Zhang Yong-kang hu State Key Laboratory of Fine Chemicals Dalian University of TechnologyDalian 116024China Department of Inorganic and Physical Chemistry COMOC-Centerfor Ordered MaterialsOrganornetallics and CatalysisGhent UniversityKrijgslaan 281-53 9000 GhentBelgium Liaoning Key Laboratory of Petrochemical Technology and Equipments Dalian 116024China Dalian Institute of Chemical Physics Chinese Academy of SciencesDalian 116023China

Two types of Mo containing metal-organic frameworks,denoted as Mo@COMOC-4 and PMA@MIL-101（Cr）,were synthesized respectively by a post-synthetic modification and a ship-in-bottle *** catalytic performance of both compounds in the epoxidation of propylene using cumene hydroperoxide（CHP） as oxidant was compared with MoO3@SiO2.A higher conversion（46.2%） and efficiency（87.4%） of CHP was observed for Mo@COMOC-4,whereas the heteropoly acids supported MIL-101 resulted in the decomposition of CHP due to its strong acidic *** tests demonstrated that Mo@COMOC-4 could be reused for multiple runs without significant loss in both activity and stability.

关键词： Metal-organic framework Molybdenum Cumene hydroperoxide Propylene epoxidation

镁单晶塑性变形行为的晶体塑性耦合孪晶相场模拟

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Acta Mechanica Sinica 2024年第3期40卷 123-144页

作者：胡佳晨徐波于超康国政 Applied Mechanics and Structure Safety Key Laboratory of Sichuan Province School of Mechanics and Aerospace EngineeringSouthwest Jiaotong UniversityChengdu611756China Failure Mechanics and Engineering Disaster Prevention Key Laboratory of Sichuan ProvinceSichuan UniversityChengdu610065China Institute of Applied Mechanics State Key Laboratory of Traction PowerSouthwest Jiaotong UniversityChengdu610031China

本文建立了一个晶体塑性-孪晶相场耦合模型来研究镁单晶的塑性变形行为.在晶体塑性模型中考虑了三种典型的滑移模式,即基面滑移、柱面滑移、锥面滑移,而在孪晶相场模型中考虑了化学能、梯度能和弹性能的作用.模拟结果表明:在沿孪生方向... 详细信息

本文建立了一个晶体塑性-孪晶相场耦合模型来研究镁单晶的塑性变形行为.在晶体塑性模型中考虑了三种典型的滑移模式,即基面滑移、柱面滑移、锥面滑移,而在孪晶相场模型中考虑了化学能、梯度能和弹性能的作用.模拟结果表明:在沿孪生方向剪切加载诱导孪晶的过程中,不同阶段的应力水平和不同方向孪晶界面的迁移率存在较大差异.孪晶在早期呈透镜状,而在侧向长大阶段呈平板状,并且孪晶出现后有基面滑移被激活;非基面滑移在基体完全转变为孪晶后被激活.在一个拉-压载荷周期内,不同取向的镁单晶中出现不同的塑性变形模式,当加载方向平行于c轴时,对应的变形模式为孪生-解孪-锥面滑移-复孪生;当加载方向垂直于c轴时,对应的变形模式为柱面滑移-柱面滑移孪生-孪生-解孪,这两种单晶均表现出强拉压不对称性;当加载方向与c轴夹角为45°时,仅发生基面滑移,不存在拉压不对称现象.

关键词： Magnesium single crystal Phase field model Twinning Dislocation slipping Crystalline orientation

High-timing-precision detection of single X-ray photons by superconducting nanowires

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National Science Review 2024年第1期11卷 194-203页

作者： Shuya Guo Jingrou Tan Hengbin Zhang Jinguang Wang Tianhao Ji Labao Zhang Xiaolong hu Jian Chen Jun Xie Kai Zou Yun Meng Xiaomin Bei Ling-An Wu Qi Chen Hao Wang Xuecou Tu Xiaoqing Jia Qing-Yuan Zhao Lin kang Peiheng Wu Research Institute of Superconductor Electronics Nanjing University Qian Xuesen Laboratory of Space Technology Beijing National Laboratory of Condensed Matter Physics Institute of Physics Chinese Academy of Sciences Hefei National Laboratory School of Precision Instrument and Optoelectronic Engineering Tianjin University Key Laboratory of Optoelectronic Information Science and Technology Ministry of Education

Precisely acquiring the timing information of individual X-ray photons is important in both fundamental research and practical applications. The timing precision of commonly used X-ray single-photon detectors remains in the range of one hundred picoseconds to microseconds. In this work, we report on high-timing-precision detection of single X-ray photons through the fast transition to the normal state from the superconductive state of superconducting nanowires. We successfully demonstrate a free-running X-ray single-photon detector with a timing resolution of 20.1 ps made of 100-nm-thick niobium nitride film with an active area of 50 μm by 50 μm. By using a repeated differential timing measurement on two adjacent X-ray single-photon detectors, we demonstrate a precision of 0.87 ps in the arrival-time difference of X-ray photon measurements. Therefore, our work significantly enhances the timing precision in X-ray photon counting, opening a new niche for ultrafast X-ray photonics and many associated applications.

关键词： single-photon detection timing precision superconductor ultrafast phenomenon pulsar X-ray navigation