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Rare Metals 2015年第12期34卷 844-850页

作者： Xiang-Hong Xu yan-Qing yang Xian Luo Lin Qin Ju-Hong lou Qing Sun Shazhou Polytechnic Institute of Technology State key Laboratory of Solidification Processing Northwestern Polytechnical University

The consolidation process of SiCf/Ti-6Al-4V composites by matrix-coated fiber (MCF) method via hot pressing was investigated using finite element modeling (FEM). By analyzing the elastic–plastic contact deformation of the representative aligned coated fibers, the consolidation maps delineating the time–temperature–pressure relationship for full densification were constructed. Both the flow coefficient and the contact area coefficient used to describe the contact deformation were calculated according to the model. In addition, the effect of fiber content on matrix stress distribution was analyzed. The results show that fiber content is a significant factor that influences the densification process. Higher fiber content will lower the consolidation rate.

关键词： Titanium matrix composites Consolidation Finite element modeling Matrix-coated fiber

Effect of Heat Treatment on Microstructure and Stress Rupture Properties of a Ni–Mo–Cr–Fe Base Corrosion-Resistant Superalloy

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Acta Metallurgica Sinica(English Letters) 2019年第1期32卷 116-126页

作者： Tao Liu Mei yang Jun-Song Wang Jia-Sheng Dong Li Wang Lang-Hong lou Jiangsu University of Technology Harbin Engineering University Institute of Metal Research Chinese Academy of Sciences

The influences of heat treatment and test condition on the microstructure and stress rupture properties of a Ni–Mo–Cr–Fe base corrosion-resistant superalloy have been investigated in this paper. Optical microscope and scanning electron microscope were employed for the microstructure observation, and X-ray diffraction, electron probe micro-analyzer, and transmission electron microscope were used for phase determination. It was found that the grain size increased and the volume fractions of initial M_6C carbides decreased along with the increase in solution treatment temperature. When tested at 650 °C/320 MPa, the stress rupture lives decreased with the increase in solution treatment temperature, but the stress rupture lives increased slightly at first and then decreased for the samples solution heat treated at 1220 °C when tested at 700 °C/240 MPa. The elongations showed the descendent trends under these two conditions. The stress rupture life and elongation for the aged samples all showed a noticeable improvement at 650 °C/320 MPa, but there was no noticeable improvement at 700 °C/240 MPa. The reasons can be attributed to the grain size, test conditions, and the initial and secondary carbides.

关键词： Corrosion-resistant superalloy Heat treatment Stress rupture properties Secondary carbides

Effect of magnetic fields on pulse plating of cobalt films

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Rare Metals 2012年第2期31卷 125-129页

作者： yu, yundan Li, Wei lou, Junwei Ge, Hongliang Sun, Lixia Jiang, Li Wei, Guoying College of Material Science and Engineering China Jiliang University Hangzhou 310018 China

Magnetic fields parallel to the electrodes were introduced during a pulse plating process to obtain cobalt thin films from alkaline baths. Ef-fects of different magnetic intensities on the composition, microstructure, and magnetic properties of cobalt thin films were investigated. It was found that the deposition speed increased gradually with the increase of magnetic intensity. Almost all of the deposited films were crys-talline and showed Co(002), Co(100) peaks. With the rise on the magnetic intensity, the intensity of Co (002) peak raised gradually. Mag-netic fields would induce cobalt growing along (002) orientation. The films were densely covered with typical nodular structure. Films of smaller grain size and smooth surface could be formed under high magnetic intensity (1 T) as a result of magnetic force and MHD effects. Moreover, higher magnetic intensity induced larger saturation magnetization and lower coercivity. With the rise on magnetic intensity, cobalt contents in the films increased gradually, which led to the rise of saturation magnetization.

关键词： pulse plating magnetic field magnetization cobalt thin films

Preparation, characterization and release of methyl viologen from a novel nanoparticle delivery system with double shells of silica and PLGA

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Chinese Science Bulletin 2010年第3期55卷 263-267页

作者： yANG Hong MIyOSHI Hirokazu lou ChangChun REN ZhengLong LIU yiyao Department of Biophysics School of Life Science and Technology University of Electronic Science and Technology of China Chengdu 610054 China Radioisotope Research Center University of Tokushima Kuramoto-cho 3-18-15 Tokushima 770-8503 Japan

The use of nanotechnology in drug delivery is a rapidly expanding field. Biodegradable or nontoxic nanomaterials have the most promising application potentials in nanomedicine. Herein, we report a novel core-shell nanoparticle with double shell coatings (silica and poly(D,L-lactide-co-glycolide) (PLGA)) with the total shell thickness of (8.7 ± 1.3) nm. The outer shell of PLGA is biodegradable and used for controlled and sustained release, and the inner shell of silica is mesoporous for the preservation of the chemical radiation therapeutic of methyl viologen (MV), an oxidant that produces reactive oxygen species during cancer radiation therapy. The dissolution time course data and transmission electron microscopy images showed that the novel nanoparticles (Au@SiO2&PLGA) have been successfully prepared, and silica and PLGA coated well the gold (Au) template surfaces. Nano- capsules (MV@SiO2&PLGA) were obtained after the gold templates were dissolved using sodium cyanide. The sustained release property was characterized through detecting fluorescence quenching time course of fluorescent isothiocyanate after mixing with MV@SiO2&PLGA nanocapsules that encapsulate MV molecules. The sustained release of MV molecules could be extended to approximately four weeks. This novel delivery system has high potential in future application for the delivery of therapeutic drugs, particularly for the treatment of cancer by radiation therapy.

关键词：二氧化硅纳米粒子甲基紫精输送系统 PLGA 双壳透射电子显微镜可生物降解

环境对玻璃纤维增强PPS压制复合材料的影响作用

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宇航材料工艺 1989年第6期19卷 46-52页

作者： A.y.lou T.P.Murtha 罗金富

聚合物复合材料在工程结构件中可否应用取决于它们在湿/热环境中长期使用后的性能保持程度和尺寸稳定性。复合材料的力学性能会随着使用温度和湿度的增加而降低,并且性能降低的百分率常常和在环境中暴露的时间有关。本文对由长玻璃纤维... 详细信息

聚合物复合材料在工程结构件中可否应用取决于它们在湿/热环境中长期使用后的性能保持程度和尺寸稳定性。复合材料的力学性能会随着使用温度和湿度的增加而降低,并且性能降低的百分率常常和在环境中暴露的时间有关。本文对由长玻璃纤维和短玻璃纤维增强的压制聚苯硫醚复合材料在高温—空气、高温—水环境中长期暴露后的性能变化进行了评价。所测性能包括拉伸强度、压缩强度、弯曲强度、冲击强度和疲劳性能。在各种苛刻的湿热环境暴露试验中,PPS复合材料展示了良好的性能保留率和尺寸稳定性。单独的温度作用对PPS的影响可以忽略,但在高温—水环境暴露试验中,某些性能有一定的降低。此外还观察到,在一段较长的时间后,其性能将不再随时间继续变化。PPS复合材料暴露在高湿/热环境中,其疲劳性能基本不受影响。

关键词：玻璃纤维复合材料 PPS 环境

Phospholamban Antisense RNA Improves SR Ca^(2+)-ATPase Activity and Left Ventricular Function in STZ-induced Diabetic Rats

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Biomedical and Environmental Sciences 2013年第7期26卷 577-583页

作者： LI Jiang JIA Bao Hui SUN Jian lou Xiao Liang HU Shen Jiang Department of Emergency and ICU Fourth Affiliated Hospital of Nanchang University Zhengzhou Railway Vocational Technical College Institute of Cardiology First Affiliated Hospital Zhejiang University Medical College

Objective To study the effect of phospholamban antisense RNA （asPLB） on sarcoplasmic reticulum Ca2＋-ATPase activity and cardiac function in rats with diabetes mellitus （DM） mediated by recombinant adeno-associated virus （rAAV） vector. Methods Six weeks after the induction of DM by streptozotocin injected intraperitoneally, the rats were divided into three groups, namely： DM-rAAV-asPLB group, DM-saline group and DM group （control group）. The rats in the DM-rAAV-asPLB group were intramyocardially injected with rAAV-asPLB, the rats in the DM-saline group were injected with saline, and those in the control group did not receive any treatment. Six weeks after gene transfer, the expressions of PLB protein and PLB phosphorylation were detected by Western-blot, while the activity of sarcoplasmic reticulum （SR） Ca2＋-ATPase and left ventricular function were measured. Results The PLB protein expression level was significantly higher whereas the PLB phosphorylation, SR Ca2＋-ATPase activity and left ventricular function were significantly lower in the DM-saline group than in the control group. No significant difference was found in PLB protein expression level, PLB phosphorylation or SR Ca2＋-ATPase activity between the DM-rAAV-asPLB group and the control group. The left ventricular function in the DM-rAAV-asPLB group was poorer than in the control group and was better than in the DM-saline group. Conclusion rAAV-asPLB can down-regulate PLB protein expression and up-regulate phosphorylation and SR Ca2＋-ATPase activity, thus contributing to the improvement of in vivo ventricutar function. PLB left

关键词： Diabetes mellitus Phospholamban Sarcoplasmic reticulum Ca2+-ATPase, Gene therapy

Crystal structure of a secreted lipase from Gibberella zeae reveals a novel “double-lock” mechanism

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Protein & Cell 2010年第8期1卷 760-770页

作者： Zhiyong lou Ming Li yuna Sun ye Liu Zheng Liu Wenping Wu Zihe Rao Laboratory of Structural Biology Tsinghua UniversityBeijing 100084China Novozymes China 14 Xinxi LuShangdi ZoneHaidian DistrictBeijing 100085China National Laboratory of Biomacromolecules Institute of BiophysicsChinese Academy of SciencesBeijing 100101China

Fusarium graminearum(sexual stage:Gibberella zeae)is the causative agent of Fusarium Head Blight(FHB),which is one of the most destructive plant disease of cereals,accounting for high grain yield losses,especially for wheat and *** other fungal pathogens,several extracellular enzymes secreted by *** are known to be involved in host *** these secreted lipases,*** lipase(GZEL),which is encoded by the FGL1 gene,was demonstrated to be crucial to *** ***,the precise mechanism of GZEL remains unclear due to a lack of detailed structural *** this study,we report the crystal structure of GZEL at the atomic *** structure of GZEL displays distinct structural differences compared to reported homologues and indicates a unique“double lock”enzymatic *** gain insight into substrate/inhibitor recognition,we proposed a model of GZEL in complex with substrate and the lipase inhibitor ebelactone B(based on the reported structures of GZEL homologues),which defines possible substrate binding sites within the catalytic cleft and suggests an“anti sn-l”binding *** results pave the way to elucidating the mechanism of GZEL and thus provide clues for the design of anti-FHB inhibitors.

关键词： lipase Gibberella zeae crystal structure mechanism inhibitor

Upper Paleozoic Marine Shale Characteristics and Exploration Prospects in the Northwestern Guizhong Depression,South China

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Journal of Ocean University of China 2018年第4期17卷 773-790页

作者： ZHU Zhenhong yAO Genshun lou Zhanghua JIN Aimin ZHU Rong JIN Chong CHEN Chao Ocean College Zhejiang UniversityZhoushan 310058China Hangzhou Institute of Petroleum Geology Hangzhou 310023China Zhejiang Institute of Geology and Mineral Rescource Hangzhou 310007China

Multiple sets of organic-rich shales developed in the Upper Paleozoic of the northwestern Guizhong Depression in South China. However, the exploration of these shales is presently at a relatively immature stage. The Upper Paleozoic shales in the northwestern Guizhong Depression, including the Middle Devonian Luofu shale, the Nabiao shale, and the Lower Carboniferous yanguan shale, were investigated in this study. Mineral composition analysis, organic matter analysis(including total organic carbon(TOC) content, maceral of kerogen and the vitrinite reflection(Ro)), pore characteristic analysis(including porosity and permeability, pore type identification by SEM, and pore size distribution by nitrogen sorption), methane isothermal sorption test were conducted, and the distribution and thickness of the shales were determined, Then the characteristics of the two target shales were illustrated and compared. The results show that the Upper Paleozoic shales have favorable organic matter conditions(mainly moderate to high TOC content, type Ⅰ and Ⅱ_1 kerogen and high to over maturity), good fracability potential(brittleness index(BI) > 40%), multiple pore types, stable distribution and effective thickness, and good methane sorption capacity. Therefore, the Upper Paleozoic shales in the northern Guizhong Depression have good shale gas potential and exploration prospects. Moreover, the average TOC content, average BI, thickness of the organic-rich shale(TOC > 2.0 wt%) and the shale gas resources of the Middle Devonian shales are better than those of the Lower Carboniferous shale. The Middle Devonian shales have better shale gas potential and exploration prospects than the Lower Carboniferous shales.

关键词： shale gas shale characteristics exploration prospects Guizhong Depression South China

Recent advances in low-dimensional semiconductor nanomaterials and their applications in high-performance photodetectors

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InfoMat 2020年第2期2卷 291-317页

作者： Jingzhi Fang Ziqi Zhou Mengqi Xiao Zheng lou Zhongming Wei Guozhen Shen State key Laboratory of Superlattices and Microstructures Institute of SemiconductorsChinese Academy of Sciences&Center of Materials Science and Optoelectronics EngineeringUniversity of Chinese Academy of SciencesBeijingChina Beijing Academy of Quantum Information Sciences BeijingChina

Low-dimensional(including two-dimensional[2D],one-dimensional[1D],and zero-dimensional[0D])semiconductor materials have great potential in electronic/optoelectronic applications due to their unique structure and *** 2D(such as transition metal dichalcogenides and black phosphorus)and 1D(such as NWs)materials have demonstrated superior performance in field effect transistors,photodetectors(PDs),and some flexible *** in some hybrid structures of 0D materials and 1D or 2D materials,the modification of 1D and 2D devices by 0D materials is *** type of hybrid heterostructure has a larger performance optimization compared with the *** the application of PDs,the variety of lowdimensional materials and properties enable wide-spectrum detection from ultraviolet UV to infrared,which provide a potential option for PDs under various *** flexible electronic devices,high performance and mechanical stability are two important ***-dimensional materials offer unparalleled advantages in flexible *** this review,we will focus on the various low-dimensional materials that have been extensively studied and their applications in the electronics/optoelectronic and flexible *** the composition and lattice structure of materials(including alloys)to the construction of various devices and heterostructures,we will introduce their application and recent development under various *** works can provide valuable guidance for the construction and application of more highperformance and multifunctional devices.

关键词： flexible devices low-dimensional semiconductor materials photodetectors

New Measurements for ^(8)He Excited States

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Chinese Physics Letters 2012年第8期29卷 69-72页

作者： XIAO Jun yE yan-Lin CAO Zhong-Xin JIANG Dong-Xing ZHENG Tao HUA Hui LI Zhi-Huan LI Xiang-Qing GE yu-Cheng lou Jian-Ling PANG Dan-yang LV Lin-Hui LI Qi-Te QIAO Rui yOU Hai-Bo CHEN Rui-Jiu H.Sakurai H.Otsu M.Nishimura S.Sakaguchi H.Baba y.Togano k.yoneda LI Chen WANG Shuo WANG He LI kuo-Ang y.Nakayama y.kondo S.Deguchi y.Satou k.H.Tshoo School of Physics and State key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871 RIkEN 2-1HirosawaWakoSaitama 351-0198Japan Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000 Department of Physics Tokyo Institute of TechnologyJapan School of Physics Seoul National UniversityKorea

Breakup reactions of the double borromean nucleus ^(8)He were measured at 82.3 MeV/u on CH2 and C *** coincident detection of two decaying neutrons and the high performance for neutron cross talk rejection are realized in this *** relative energy spectrum for ^(8)He was reconstructed with good *** spectrum exhibits a structure of two resonant peaks,one at an excitation energy of about 3.0 and the other at about 4.14 MeV,*** larger cross section for the first resonance is observed in comparison to the results reported previously.

关键词： experiment MeV/u spectrum