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Progress in Physics and Technology Developments for the Modification of JT-60

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Plasma Science and Technology 2004年第1期6卷 2141-2150页

作者： H.Tamai M.Matsukawa G.kurita N.Hayashi k.Urata Y.M.Miura k.kizu k.tsuchiya A.Morioka Y.kudo S.Sakurai k.Masaki T.Suzuki M.Takechi Y.kamada A.Sakasai S.Ishida k.Abe A.Ando T.Cho T.Fujii T.Fujita S.Goto k.Hananda A.Hatayama T.Hino H.Horiike N.Hosogane M.Ichimura Tsuji-Iio S.Itoh M.katsurai M.kikuchi A.kohyama H.kubo M.kuriyama M.Matsuoka Y.Miura N.Miya T.Mizuuchi k.Nagasaki H.Ninomiya N.Nishino Y.Ogawa k.Okano T.Ozeki M.Saigusa M.Sakamoto M.Satoh M.Shimada R.Shimada M.Shimizu T.Takagi Y.Takase T.Tanabe k.Toi Y.Ueda Y.Uesugi k.Ushigusa Y.Yagi T.Yamamoto k.Yatsu k.Yoshikawa Japan Atomic Energy Research Institute Naka Ibarahi 311-0193 Japan Tohoku University University of Tsukuba Osaka University kyushu University keio University Hokkaido University Tokyo Institute of Technology the University of Tokyo kyoto University Mie University Hiroshima University Central research Institute of Electric Power Industry Ibaraki University ITER JCT Nagoya University National Institute for Fusion Science kanazawa University National Institute of Advanced Industrial Science and Technology

Recent progress in the physics and engineering design study for themodification programme of JT-60 is presented. In order to achieve a steady state high-βplasmaoperation, which is the dominant issue of this programme, physics design for the MHD control and thestability analysis is investigated. Engineering design and the R & D for the superconducting coils,irradiation shield are performed well towards the mission of programme.

关键词： modification of JT-60 physics design technology developments

Development on In-Reactor Observation System Using Cherenkov Light

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Development on In-Reactor Observation System Using Cherenkov...

评估数字相位对比乳腺X线摄影系统的乳腺X线片计算机辅助检测病变的能力

作者： k.tsuchiya S.kitagishi Y.Nagao N.Takemoto M.Naka A.kimura T.Sano H.Unezaki T.Yoshimoto k.Nakajima Y.Fujiwara Y.Okumura S.Yamamoto Neutron Irradiation and Testing Reactor Center JAEA

INTRODUCTION:The Cherenkov light is a faint emission accompanying the passage of charged particles through a transparent medium at speeds faster than the speed of light in that *** high-energy gamma rays can generate high-velocity electrons by Compton scattering,Cherenkov light can be emitted as a result of gamma radiation fields as ***,the Cherenkov Viewing Device(CVD) was developed as an instrument specifically designed to form an image of the UV portion of this glow and it is used routinely by the

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国际医学放射学杂志 2010年第1期 98-98页

作者： T.Tanaka N.Nitta S.Ohta T.kobayashi A.kano k.tsuchiya 朱慧玲 Department of Radiology Shiga University of Medical ScienceTsukinowa-choSetaOtsuShiga 520-2192Japan

评价计算机辅助检测(CAD)系统对数字相位对比乳腺X线摄影(PCM)系统摄片图像中检测微小钙化和肿块的能力,PCM系统是以相位对比和25μm像素的高分辨率乳腺X线摄影提供的清晰图像为特征。从大约3500例乳腺X线片中收集50例正常的和50例异常... 详细信息

评价计算机辅助检测(CAD)系统对数字相位对比乳腺X线摄影(PCM)系统摄片图像中检测微小钙化和肿块的能力,PCM系统是以相位对比和25μm像素的高分辨率乳腺X线摄影提供的清晰图像为特征。从大约3500例乳腺X线片中收集50例正常的和50例异常的乳腺X线摄影打印成胶片并在观片灯上阅片。7名有

关键词：辅助检测相位对比乳腺乳房计算机

Ab Initio Two-Phase Molecular Dynamics on the Melting Curve of SiO_2

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Journal of Earth Science 2010年第5期21卷 801-810页

作者： Yusuke Usui Taku tsuchiya Geodynamics Research Center Ehime University

Ab initio two-phase molecular dynamics simulations were performed on silica at pressures of 20-160 GPa and temperatures of 2 500-6 000 k to examine its solid-liquid phase boundary. Results indicate a melting temperature （Tin） of 5 900 k at 135 GPa. This is 1 100 k higher than the temperature considered for the core-mantle boundary （CMB） of about 3 800 k. The calculated melting temperature is fairly consistent with classical MD （molecular dynamics） simulations. For liquid silica, the O-O coordination number is found to be 12 along the Tm and is almost unchanged with increasing pressure. The self-diffusion coefficients of O and Si atoms are determined to be 1.3×10^-9-3.3×10^-9 m2/s, and the viscosity is 0.02-0.03 Pa＇s along the Tin. We find that these transport properties depend less on pressure in the wide range up of more than 135 GPa. The eutectic temperatures in the MgO-SiO2 systems were evaluated and found to be 700 k higher than the CMB temperature, though they would decrease considerably in more realistic mantle compositions.

关键词： Ab Initio Two-Phase Molecular Dynamics on the Melting Curve of SiO2 SiO CMB MgO than

Crystal orientation-dependent fatigue characteristics in micrometer-sized single-crystal silicon

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Microsystems & Nanoengineering 2016年第1期2卷 154-162页

作者： Tsuyoshi Ikehara Toshiyuki tsuchiya National Institute of Advanced Industrial Science and Technology(AIST) 1-2 NamikiTsukubaIbaraki 305-8564Japan Department of Micro Engineering Graduate School of EngineeringKyoto UniversityKyotodaigaku-Katsura C3Nishikyo-kuKyoto 615-8540Japan

Repetitive bending fatigue tests were performed using five types of single-crystal silicon specimens with different crystal orientations fabricated from{100}and{110}*** lifetimes in a wide range between 100 and 1010 were obtained using fan-shaped resonator test *** surface observation via scanning electron microscope(SEM)revealed that the{111}plane was the primary fracture *** crack propagation exponent n was estimated to be 27,which was independent of the crystal orientation and dopant concentration;however,it was dependent on the surface conditions of the etched *** fatigue strengths relative to the deflection angle were orientation dependent,and the ratios of the factors obtained ranged from 0.86 to *** strength factors were compared with those obtained from finite element method stress *** calculated stress distributions showed strong orientation dependence,which was well-explained by the elastic *** comparison of the strength factors suggested that the first principal stress was a good criterion for fatigue *** include comparisons with specimens tested in our previous report and address the tensile strength,initial crack length,volume effect,and effects of surface roughness such as scallops.

关键词： fatigue fracture lifetime MEMS reliability resonator single-crystal silicon

Expanding-contracting Earth

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Geoscience Frontiers 2013年第3期4卷 341-347页

作者： Taku tsuchiya kenji kawai Shigenori Maruyama Geodynamic Research Center Ehime UniversityMatsuyamaEhime 790-8577Japan Department of Earth and Planetary Sciences Tokyo Institute of TechnologyMeguroTokyo 152-8551Japan Department of Earth Science University of CaliforniaSanta Barbara 93106CAUSA

The Earth was born from a giant impact at 4.56 Ga. It is generally thought that the Earth subsequently cooled, and hence shrunk, over geologic time. However, if the Earth＇s convection was double-layered, there must have been a peak of expansion during uni-directional cooling. We computed the expansion- contraction effect using first principles mineral physics data. The result shows a radius about 120 km larger than that of the present Earth immediately after the consolidation of the magma-ocean on the surface, and subsequent shrinkage of about 110 km in radius within about 10 m.y., followed by gradual expansion of 11 km in radius due to radiogenic heating in the lower mantle in spite of cooling in the upper mantle in the Archean. This was due to double-layered convection in the Archean with final collapse of overturn with contraction of about g km in radius, presumably by the end of the Archean. Since then, the Earth has gradually cooled down to reduce its radius by around 12 km. Geologic evidence supports the late Archean mantle overturn ca. 2.6 Ga, such as the global distribution of super-liqnidus flood basalts on nearly all cratonic fragments （〉35 examples）. If our inference is correct, the surface environment of the Earth must have undergone extensive volcanism and emergence of local landmasses, because of the thin ocean cover （3-5 km thickness）. Global unconformity appeared in cratonic fragments with stromatolite back to 2.9 Ga with a peak at 2.6 Ga. The global magmatism brought extensive crustal melting to yield explosive felsic volcanism to transport volcanic ash into the stratosphere during the catastrophic mantle overturn. This event seems to be recorded by sulfur mass-independent fractionation （SMIF） at 2.6 Ga. During the mantle overturn, a number of mantle plumes penetrated into the upper mantle and caused local upward doming of by ca. 2-3 km which raised local landmasses above sea-level. The consequent increase of atmospheric oxygen enabled life evolutio

关键词： Mantle overturn Expanding Earth Global unconformity Nutrients Eukaryotes

Field observations of debris-flow initiation processes on sediment deposits in a previous deep-seated landslide site

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Journal of Mountain Science 2016年第2期13卷 213-222页

作者： Fumitoshi IMAIZUMI Satoshi tsuchiya Okihiro OHSAkA Department of Environment and Forest Resources Science Faculty of AgricultureShizuoka University

Although information regarding the initiation processes of debris flows is important for the development of mitigation measures,field data regarding these processes are *** conducted field observations of debris-flow initiation processes in the upper Ichinosawa catchment of the Ohya landslide,central *** 19 June 2012,our videocamera monitoring systems recorded the moment of debris-flow initiation on channel deposits(nine surges) and talus slopes(eight surges).The initiation mechanisms of these surges were classified into three types by analyzing the video images: erosion by the surface flow,movement of deposits as a mass,and upward development of the fluid *** first type was associated with the progress of surface flow from the upper stream on unsaturated channel *** second type was likely caused by an increase in the pore water pressure associated with the rising in the groundwater level in channel deposits;a continuous water supply from the upper stream by the surface flow might have induced this *** third type was associated with changes in the downstream topography caused by *** flow velocity of most surges was less than 3 m s^(-1) and they usually stopped within 100 m from the initiation *** with abundant pore fluid had a higher flow velocity(about 3- 5 m s^(-1)) and could travel for alonger *** observations indicate that the surface flow plays an important role in the initiation of debris flows on channel deposits and talus slopes.

关键词： Debris flow Initiation zone Field monitoring Ohya landslide

Anticancer effect of adenosine on gastric cancer via diverse signaling pathways

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World Journal of Gastroenterology 2015年第39期21卷 10931-10935页

作者： Ayako tsuchiya Tomoyuki Nishizaki Division of Bioin- formation Department of Physiology Hyogo College of Medicine

Extracellular adenosine induces apoptosis in a variety of cancer cells via intrinsic and extrinsic pathways. In the former pathway, adenosine uptake into cells triggers apoptosis, and in the latter pathway, adenosine receptors mediate apoptosis. Extracellular adenosine also inducesapoptosis of gastric cancer cells. Extracellular adenosine is transported into cells through an adenosine transporter and converted to AMP by adenosine kinase. In turn, AMP activates AMP-activated protein kinase(AMPk). AMPk is the factor responsible for caspase-independent apoptosis of GT3-TkB gastric cancer cells. Extracellular adenosine, on the other hand, induces caspase-dependent apoptosis of MkN28 and MkN45 gastric cancer cells by two mechanisms. Firstly, AMP, converted from intracellularly transported adenosine, initiates apoptosis, regardless of AMPk. Secondly, the A3 adenosine receptor, linked to Gi/Gq proteins, mediates apoptosis by activating the Gq protein effector, phospholipase Cγ, to produce inositol 1,4,5-trisphosphate and diacylglycerol, which activate protein kinase C. Consequently, the mechanisms underlying adenosine-induced apoptosis vary, depending upon gastric cancer cell types. Understand the contribution of each downstream target molecule of adenosine to apoptosis induction may aid the establishment of tailor-made chemotherapy for gastric cancer.

关键词： Adenosine Apoptosis Intrinsic pathway Extrinsic pa

Liver stem cells:Plasticity of the liver epithelium

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World Journal of Gastroenterology 2019年第9期25卷 1037-1049页

作者： Atsunori tsuchiya Wei-Yu Lu Division of Gastroenterology and Hepatology Graduate school of medical and dental sciences Niigata University Centre for Liver and Gastrointestinal Research Institute of Immunology and Immunotherapy the University of Birmingham

The liver has a high regenerative capacity after acute liver injury, but this is often impaired during chronic liver injury. The existence of a dedicated liver stem cell population that acts as a source of regeneration during chronic liver injury has been controversial. Recent advances in transgenic models and cellular reprogramming have provided new insights into the plasticity of the liver epithelium and directions for the development of future therapies. This article will highlight recent findings about the cellular source of regeneration during liver injury and the advances in promoting liver regeneration.

关键词： Liver regeneration Stem cells Cellular plasticity