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Serum Intestinal Fatty Acid Binding Protein in Patients with Small Bowel Obstruction

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Surgical Science 2013年第6期4卷 302-307页

作者： kaoru Sakamoto Tatsuo kanda takeo Bamba Hiroyuki Funaoka Shin-ichi kosugi kazuhito Yajima Takashi Ishikawa Division of Digestive and General Surgery Niigata University Graduate School of Medical and Dental Sciences Niigata Japan DS Pharma Biomedical Co. Ltd. Osaka Japan

Purpose: The aims of this pilot study were to reveal the biological characteristics of serum I-FABP and explore its clinical utility as a biomarker in patients with small bowel obstruction (SBO). Methods: Serum I-FABP levels were measured in 37 consecutive patients with SBO between 2007 and 2008. Serum I-FABP levels were compared between ischemia (n = 10) and non-ischemia (n = 27) groups. Serum I-FABP levels were longitudinally analyzed in 21 patients who showed high (>2.0 ng/ml) serum I-FABP levels. The relationship between serum I-FABP level and length of damaged bowel was also analyzed. Results: Median serum I-FABP levels were 9.2 ng/ml in the ischemia group and 1.9 ng/ml in the non-ischemia group (p ker for detecting small-bowel ischemia.

关键词： Biomarker I-FABP Small Bowel Obstruction Strangulation

膜孔中有线形接枝链的微囊的分子识别型控制释放特性研究(英文)

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四川大学学报（工程科学版） 2002年第5期34卷 80-84页

作者：褚良银朱家骅陈文梅 takeo Yamaguchi Shin-ichi Nakao 四川大学化工学院四川成都610065 Dept.of Chem.System Eng.The Univ.of Tokyo

研制出了一种用于环境刺激感应型控制释放的分子识别型微囊。该微囊具有核壳结构多孔膜、并在膜孔中接枝有作为分子识别开关的聚 [异丙基丙烯酰胺 -共 - (苯并 - 1 8-冠 - 6 -丙烯酰胺 ) ] (poly(NIPAM co BCAm) )线形链。采用了界面聚... 详细信息

研制出了一种用于环境刺激感应型控制释放的分子识别型微囊。该微囊具有核壳结构多孔膜、并在膜孔中接枝有作为分子识别开关的聚 [异丙基丙烯酰胺 -共 - (苯并 - 1 8-冠 - 6 -丙烯酰胺 ) ] (poly(NIPAM co BCAm) )线形链。采用了界面聚合法制备核壳结构多孔微囊膜 ,并采用了等离子体接枝填孔聚合法在膜孔内接枝poly(NIPAM co BCAm)线形链。囊内溶质从该微囊中的释放特性明显受环境溶液中Ba2 + 离子的存在与否状态所控制。当环境溶液中没有BaCl2 分子存在时 ,由于微囊膜孔内接枝的poly(NIPAM co BCAm)聚合物链呈收缩状态而使膜孔开启 ,所以释放速度快 ;相反 ,当环境溶液中有BaCl2 分子存在时 ,微囊膜孔内接枝的poly(NIPAM co BCAm)链呈膨胀状态 ,于是膜孔关闭 ,从而导致释放速度变得很慢。该具有poly(NIPAM co BCAm)

关键词：膜孔线形接枝链微囊分子识别控制释放刺激感应相变可逆性可重复性

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Fabrication and Characterization of Poly[Decaphenylcyclopentasilane]-Based Solar Cells

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Advances in Materials Physics and Chemistry 2012年第3期2卷 121-125页

作者： Makoto Iwase takeo Oku Atsushi Suzuki Tsuyoshi Akiyama katsuhisa Tokumitsu Masahiro Yamada Mika Nakamura Department of Materials Science The University of Shiga Prefecture Hikone Japan Osaka Gas Chemicals Co. Ltd. Osaka Japan

Poly[decaphenylcyclopentasilane] (PDPS)-based photovoltaic cells were fabricated by using mixture solution of PDPS including boron and phosphorous elements. A doping effect of phosphorus and boron into PDPS was investigated on the performance of the photovoltaic devices. The solar cell provided short-circuit current density of 0.11 mA/cm2 and open-circuit voltage of 0.81 V under simulated sunlight. Microstructural analysis indicated that PDPS had an amor-phous structure, which would result in the photovoltaic properties.

关键词： PDPS Polysilane Solar Cell Amorphous Silicon

Enhancement of Ethanol Production from Napiergrass (<i>Pennisetum purpureum</i>Schumach) by a Low-Moisture Anhydrous Ammonia Pretreatment

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Journal of Sustainable Bioenergy Systems 2013年第3期3卷 179-185页

作者： Masahide Yasuda keisuke takeo Hayato Nagai Takuya Uto Toshifumi Yui Tomoko Matsumoto Yasuyuki Ishii kazuyoshi Ohta Center for Collaborative Research and Community Cooperation University of Miyazaki Miyazaki Japan Department of Animal and Grassland Sciences Faculty of Agriculture University of Miyazaki Miyazaki Japan Department of Applied Chemistry Faculty of Engineering University of Miyazaki Miyazaki Japan Department of Biochemistry and Applied Biosciences Faculty of Agriculture University of Miyazaki Miyazaki Japan

Napiegrass (Pennisetum purpureum Schumach) was treated with a low-moisture anhydrous ammonia (LMAA) pretreatment by adding an equal weight of water and keeping it under atmospheric ammonia gas at room temperature for four weeks. After the removal of ammonia and washing with water, a simultaneous saccharification and fermentation (SSF) was conducted for the LMAA-pretreated napiergrass (1.33 g) in a buffer solution (8 mL) using a mixture of a cellulase (80 mg) and a xylanase (53 mg) as well as the cell suspension (0.16 mL) of Saccharomyces cerevisiae. Ethanol and xylose resulted in 91.2% and 62.9% yields, respectively. The SSF process was scaled up using LMAA-pretreated napiergrass (100.0 g) to give ethanol (77.2%) and xylose (52.8%). After the removal of ethanol, the pentose fermentation of the SSF solution (40 mL), which contained 1.00 g of xylose, using cell suspension of Escherichia coli kO11 (70 mL) gave 86.3% yield of ethanol. Total ethanol yield reached 68.9% based on xylan (21.4 wt%) and glucan (39.7 wt%) of the LMAA-pretreated napiergrass.

关键词： LMAA SSF Cellulase Xylanase Saccharomyces cerevisiae Escherichia coli kO11

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活性N-甲基氨基甲酸酯的简易合成法

农药译丛 1993年第6期15卷 32-35页

作者： takeo konakahara 韩金庆日本东京科技大学

近年来,三氯甲基氯代甲酸酯(1)或双-(三氯甲基)碳酸酯(2)经常作为光气资源用于有机合成中。较之高毒的光气,这些液态或结晶状的光气同效体则具有更易贮存的优点。通常,化合物(1)和(2)用于羟基或氨基的氯甲基化或羧化反应、羧酸的氯化反... 详细信息

近年来,三氯甲基氯代甲酸酯(1)或双-(三氯甲基)碳酸酯(2)经常作为光气资源用于有机合成中。较之高毒的光气,这些液态或结晶状的光气同效体则具有更易贮存的优点。通常,化合物(1)和(2)用于羟基或氨基的氯甲基化或羧化反应、羧酸的氯化反应,以及由醛制取α-氯代氯甲酸酯。以此类反应为基础,可以合成许多重要的中间体,其中一些化合物在肽类化合物的合成等得到了广泛的应用。在药物的研究中,作者合成了烷基亚硝基脲。其利用相应的氨烷基氨基酸与活化的N-甲基-N-亚硝基琥珀酰基氨基甲酸酯的耦合反应,用于嵌入到DNA甲基铃结构。

关键词：甲基氨基甲酸酯合成

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二苯醚类除草剂中间体的合成

农药译丛 1991年第4期13卷 44-52,9页

作者： takeo Yoshimoto 吴佩文日本三井东压化学公司

二苯醚类化合物作为除草剂早已引起人们的注意。六十年代初期,Robm&Haas公司在二苯醚类除草剂除草醚和甲草醚的商品化开发方面取得了成功,世界上各大化学公司由此而对这类化合物产生了兴趣。这一领域的研究开发工作已得以继续,并已开发... 详细信息

二苯醚类化合物作为除草剂早已引起人们的注意。六十年代初期,Robm&Haas公司在二苯醚类除草剂除草醚和甲草醚的商品化开发方面取得了成功,世界上各大化学公司由此而对这类化合物产生了兴趣。这一领域的研究开发工作已得以继续,并已开发出许多除草剂品种。它们都具有相同的二苯醚骨架,但作用机理和杀草谱却不相同。此类化合物仍值得进一步研究。

关键词：除草剂二苯醚中间体

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Feasibility Study for Biweekly Administration of Cisplatin plus Vinorelbine as Adjuvant-Chemotherapy for Completely Resected Non-Small Cell Lung Cancer Patients in a Japanese Population

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Advances in Lung Cancer 2014年第1期3卷 1-9页

作者： Shuichi Tsukamoto koji Yamazaki Ryo Mori Masakazu katsura Hidenori kouso Daigo kawano Chie Ushijima Sadanori takeo Division of General Thoracic Surgery Respiratory Center and Clinical Research Institute National Hospital Organization Kyushu Medical Center Fukuoka City Japan

Purpose: To evaluate the feasibility of biweekly administration of cisplatin and vinorelbine as adjuvant chemotherapy for patients with completely resected non-small cell lung cancer (NSCLC). Patients and Methods: This was a single-arm, single-institutional study. Patients with completely resected NSCLC (p-Stage IB-IIIA) with no previous chemotherapy or radiotherapy were eligible. Simon’s optimal two-stage design was applied. Both cisplatin (50 mg/m2) and vinorelbine (25 mg/m2) were given on days 1 and 15, every 28 days. The primary endpoint of this study was the feasibility of this combination in the four cycles of treatment. Results: Twenty patients (19 lobectomies and 1 pneumonectomy) were enrolled in this study. 10 (50%) of patients had grade 3/4 neutropenia, and 3 (15%) had grade 3/4 anemia. Severe non-hematologic toxicities were uncommon in this series. No treatment-related death was encountered. 18 (90%) patients completed the planned 4 cycles of chemotherapy. The median intensity was 24.3 (range 18.1 to 25) mg/m2/week with an average of 23.6 (21 - 25) mg/m2/week cisplatin and 12.5 (range 10 to 12.5) mg/m2/week with an average of 12.3 (10 - 12.5) mg/m2/week vinorelbine. The median relative dose intensity of cisplatin was 97.5% (range 72.5% to 100%) with an average of 94.6% (72.5% - 100%) and that of vinorelbine was 100% (range 80% to 100%) with an average of 97.8% (80% - 100%). Conclusion: This regimen is feasible in the treatment of patients with completely resected NSCLC. A phase III trial is warranted to assess the efficacy of this regimen at promoting survival and preventing recurrence.

关键词： NSCLC Adjuvant Chemotherapy Cisplatin and Vinorelbine Biweekly

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kCI衬底增透膜

激光与红外 1987年第10期 42-43+23页

作者： takeo Miyata 王尚铎

本发明所述kCl衬底三层耐潮增透膜,吸收10.6μm波长CO2气体激光束很小,能透足量的0.6328μm波长He-Ne激光束。第一层（紧贴衬底）是As2S3层,光学厚度是2.438～2.65μm,第二层是PbF2层,1.259～1.363μm,第三层是AS2S3层,0.959～1.03882μ... 详细信息

本发明所述kCl衬底三层耐潮增透膜,吸收10.6μm波长CO2气体激光束很小,能透足量的0.6328μm波长He-Ne激光束。第一层（紧贴衬底）是As2S3层,光学厚度是2.438～2.65μm,第二层是PbF2层,1.259～1.363μm,第三层是AS2S3层,0.959～1.03882μm。图2是第二层As2S3（即第三层）的光学厚度从预调的光学厚度增大和减小4％时,本膜系的反射与波长的关系。

关键词：增透膜 kCI 三层抗反射膜光学薄膜衬底基片光学厚度

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光学式轮廓传感器

中国检验检测 1980年第4期 9-11页

作者： takeo Sawatari 夏永健

一、引言在许多场合下,表面轮廓的测量是很重要的。使用钻石测针的机械式轮廓仪,是为此用的一种标准仪器。测针式仪器要使针尖与被测表面接触。接触测量会使针尖磨损或划伤被测表面。而另一方面,光学技术通常是非接触式的方法。已经提... 详细信息

一、引言在许多场合下,表面轮廓的测量是很重要的。使用钻石测针的机械式轮廓仪,是为此用的一种标准仪器。测针式仪器要使针尖与被测表面接触。接触测量会使针尖磨损或划伤被测表面。而另一方面,光学技术通常是非接触式的方法。已经提出过许多光学技术用以测量各种

关键词：光学式仪器测针轮廓传感器显微物镜