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国际感染病学（电子版） 2019年第1期8卷 1-7页

作者： S.m.Adnan Ali Yumna mirza m.Ozair Awan k.m.inam pal Zubair Ahmad Office of Academia and Research in Surgery Department of SurgeryAga Khan University Hospital medical College Aga Khan University Hospital Section of General Surgery Department of SurgeryAga Khan University Hospital Section of Histopathology Department of Pathology and Laboratory MedicinesAga Khan University Hospital

Objective To determine HPV infection status and expression of p16, cyclooxygenase-2(COX-2), Cyclin D1 and epidermal growth factor receptor(EGFR) in ESCC patients of Pakistan. methods 51 ESCC patients treated at Aga khan University Hospital(AkUH) were included. HPV infection status was confirmed via PCR while the expression of the four biomarkers was determined using immunohistochemistry. The correlation of all markers with patient clinicopathological features as well as each other was analyzed. Results HPV infection status and p16 overexpression was found to be negative in all the patients while COX-2, Cyclin D1 and EGFR were overexpressed in 56.9%, 62.7% and 49.0% of the patients respectively. COX-2 showed a significant correlation with tumor invasion while EGFR was shown to be significantly correlated with histological grading and COX-2 expression. Conclusion COX-2 and EGFR can be used as prognostic markers. HPV does not seem to be a causative agent for ESCC in Pakistan.

关键词： COX-2 Cyclin D1 EGFR ESCC HPV

Unraveling the role of dual Ti/mg metals on the ignition and combustion behavior of HTPB-boron-based fuel

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Defence Technology（防务技术） 2024年第2期32卷 134-143页

作者： Arijit Debnath Yash pal Sri Nithya mahottamananda Djalal Trache School of Aeronautical Science Hindustan Institute of Technology and ScienceChennai 603103India Department of Aerospace Engineering B S Abdur Rahman Crescent Institute of Science and TechnologyChennai 600048India Energetic materials Laboratory(EmLab) Teaching and Research Unit of Energetic ProcessesEcole Militaire PolytechniqueBP 17Bordj El-Bahri16046AlgiersAlgeria

metal additives play an essential role in explosive and propellant formulations. Boron(B) is widely used in propellant applications owing to its high energetic content. The addition of B to explosives and propellants increases their energy density, making them more efficient and powerful. Nevertheless, B forms oxide layers on its surface during combustion, slowing down the combustion rate and reducing rocket motor efficiency. To overcome this issue, other metal additives such as aluminum(Al), magnesium(mg),and titanium(Ti) are revealed to be effective in boosting the combustion rate of propellants. These additives may improve the combustion rate and therefore enhance the rocket motor’s performance. The present study focused on preparing and investigating the ignition and combustion behavior of pure hydroxyl-terminated polybutadiene(HTPB)-B fuel supplemented with nano-titanium and nanomagnesium. The burn rates of HTPB-B fuel samples were evaluated on the opposed flow burner(OFB)under a gaseous oxygen oxidizer, for which the mass flux ranges from 22 kg/(m^(2)·s) to 86 kg/(m^(2)·s). The addition of Ti and mg exhibited higher regression rates, which were attributed to the improved oxidation reaction of B due to the synergetic metal combustion effect. The possible combustion/oxidation reaction mechanism of B-mg and B-Ti by heating the fuel samples at 900℃ and 1100℃ was also examined in a Nabertherm burnout furnace under an oxygen atmosphere. The post-combustion products were collected and further subjected to X-ray diffraction(XRD) and field emission scanning electron microscopy(FE-SEm) analyses to inspect the combustion behavior of B-Ti and B-mg. It has been observed that the B oxide layer at the interface between B-Ti(B-mg) is removed at lower temperatures, hence facilitating oxygen transfer from the surroundings to the core B. Additionally, Ti and mg decreased the ignition delay time of B, which improved its combustion performance.

关键词： Boron B_(2)O_(3) Opposed flow burner Combustion magnesium

Evaluating Ignition and Combustion Performance with Al-metal- Organic Frameworks and Nano-Aluminum in HTPB Fuel

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火炸药学报 2024年第5期47卷 413-421,I0003页

作者： Sri Nithya mahottamananda Yash pal Yarravarapu Sai Sriram Subha S Djalal Trache Department of Aerospace Engineering B S Abdur Rahman CrescentInstitute of Science and TechnologyChennai-600048India School of Aeronautical Science Hindustan Institute of Technologyand ScienceChennai-603103India Energetic materials Laboratory(EmLab) Teaching and ResearchUnit of Energetic ProcessesEcole Militaire PolytechniqueBP 17Bordj El-Bahri16046AlgiersAlgeria

Incorporating aluminum metal-organic frameworks(Al-mOFs)as energetic additives for solid fuels presents a promising avenue for enhancing combustion *** study explores the potential benefits of Al-mOF(mIL-53(Al))energetic additive on the combustion performance of hydroxyl-terminated polybutadiene(HTPB)*** HTPB-mOF fuel samples were manufactured using the vacuum-casting technique,followed by a comprehensive evaluation of their ignition and combustion properties using an opposed flow burner(OFB)setup utilizing gaseous oxygen as an *** gauge the effectiveness of Al-mOFs as fuel additives,their impact is compared with that of nano-aluminum(nAl),another traditional additive in HTPB *** results indicate that the addition of 15%(mass fraction)nAl into HTPB resulted in the shortest ignition delay time(136 ms),demonstrating improved ignition performance compared to pure HTPB(273 ms).The incorporation of Al-mOF in HTPB also reduced ignition delay times to 227 ms and 189 ms,***,under high oxidizer mass flux conditions(79—81 kg/(m^(2)s)),HTPB fuel with 15%nAl exhibited a substantial 83.2%increase in regression rate compared to the baseline HTPB fuel,highlighting the positive influence of nAl on combustion *** contrast,HTPB-mOF with a 15%Al-mOF additive showed a 32.7%increase in regression rate compared to pure *** results suggest that HTPB-nAl outperforms HTPB-mOF in terms of regression rates,indicating a more vigorous and rapid burning behavior.

关键词： ignition combustion enhancement mOF HTPB regression rate

Improved reservoir characterization by means of supervised machine learning and model-based seismic impedance inversion in the Penobscot field,Scotian Basin

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Energy Geoscience

Energy Geoscience 2024年第2期5卷 183-201页

作者： Satya Narayan Soumyashree Debasis Sahoo Soumitra kar Sanjit kumar pal Subhra kangsabanik Oil and Natural Gas Corporation(ONGC)Limited DehradunIndia Department of Applied Geophysics IIT(ISM)DhanbadIndia

The present research work attempted to delineate and characterize the reservoir facies from the Dawson Canyon Formation in the Penobscot field,Scotian *** integrated study of instantaneous frequency,P-impedance,volume of clay and neutron-porosity attributes,and structural framework was done to unravel the Late Cretaceous depositional system and reservoir facies distribution patterns within the study *** strikes were found in the EW and NEE-SWW directions indicating the dominant course of tectonic activities during the Late Cretaceous period in the region.P-impedance was estimated using model-based seismic *** properties such as the neutron porosity(NPHI)and volume of clay(VCL)were estimated using the multilayer perceptron neural network with high ***,a combination of low instantaneous frequency(15-30 Hz),moderate to high impedance(7000-9500 gm/cc*m/s),low neutron porosity(27%-40%)and low volume of clay(40%-60%),suggests fair-to-good sandstone development in the Dawson Canyon *** calibration with the welllog data,it is found that further lowering in these attribute responses signifies the clean sandstone facies possibly containing *** present study suggests that the shale lithofacies dominates the Late Cretaceous deposition(Dawson Canyon Formation)in the Penobscot field,Scotian *** faults and overlying shale facies provide structural and stratigraphic seals and act as a suitable hydrocarbon entrapment mechanism in the Dawson Canyon Formation's *** present research advocates the integrated analysis of multi-attributes estimated using different methods to minimize the risk involved in hydrocarbon exploration.

关键词： Reservoir characterization model-based inversion multilayer perceptron(mLP) Impedance Petrophysical properties Scotian Basin

multi-Band metamaterial Antenna for Terahertz Applications

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Computers, materials & Continua 2023年第1期74卷 1765-1782页

作者： Adel Y.I.Ashyap m.inam m.R.kamarudin m.H.Dahri Z.A.Shamsan k.Almuhanna F.Alorifi Faculty of Engineering Technology Universiti Tun Hussein Onn Malaysia(UTHM)Batu Pahat86400JohorMalaysia Centre for Telecommunication Research&Innovation(CETRI) Faculty of Electrical and Electronic Engineering TechnologyUniversiti Teknikal Malaysia Melaka(UTeM)Melaka76100Malaysia Department of Electronic Engineering Dawood University of Engineering and Technology74800KarachiPakistan Electrical Engineering Department College of EngineeringImam Mohammad Ibn Saud Islamic UniversityRiyadhSaudi Arabia

A multi-band metamaterial antenna is proposed to operate at the terahertz(THz)band for medical *** proposed structure is designed on a polyimide as a support layer,and its radiating elements are made of ***,the design is started with a conventional shape showing a single operating frequency at 1.1 *** achieve a multi-band operating frequency,the conventional shape was replaced with the proposed metamaterial as a radiating patch that has properties not exist in *** multi-band frequencies are obtained without compromising the overall size of the *** overall size is 600×600×25μm^(3).The operating frequencies are 0.36,0.49,0.69,0.87,and 1.04 THz.A full ground plane is used to behave as isolation between the design and the human body *** proposed design is investigated on free space and on the human body model,showing excellent performance in both *** achieved gains for the following frequencies 0.36,0.49,0.69,0.87,and 1.04 THz are 4.81,6.5,8.41,6.02,and 7.96 dB,respectively,while the efficiencies are 83.91%,96.28%,90.80%,91.71%,and 92.99%,*** conventional design was modified to have a partial ground to show the benefit of using the full *** design is loaded on the human body model and its performance is *** efficiency and gain are 6.61 dB and 95.58.7%for the case of no human body model,and 4.26 dB and 40.30%for the case of using a human body ***,the proposed metamaterial antenna will be useful for future medical applications in the THz band.

关键词： THz 5G a multi-band metamaterials 6G WBAN

Incidence of urinary incontinence following endoscopic laser enucleation of the prostate by en-bloc and non-en-bloc techniques:a multicenter,real-world experience of 5068 patients

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Asian Journal of Andrology 2024年第3期26卷 233-238页

作者： Daniele Castellani Vineet Gauhar khi Yung Fong mario Sofer moisés Rodríguez Socarrás Azimdjon N Tursunkulov Lie kwok Ying Sarvajit Biligere Ho Yee Tiong Dean Elterman Abhay mahajan mark Taratkin Sorokin Nikolai Ivanovich Tanuj pal Bhatia Dmitry Enikeev Nariman Gadzhiev mohammed Taif Bendigeri Jeremy Yuen-Chun Teoh marco Dellabella Fernando Gómez Sancha Bhaskar kumar Somani Thomas Reinhard William Herrmann Urology Unit IRCCS INRCAAncona 60127Italy Urology Unit Marche University HospitalLe Marche Polytechnic UniversityAncona 60126Italy Department of Urology Ng Teng Fong General HospitalSingapore 609606Singapore Yong Loo Lin School of medicine National University of SingaporeSingapore 117597Singapore Department of Urology Tel Aviv Sourasky Medical CenterAffiliated to the Sackler School of MedicineTel Aviv UniversityTel Aviv 6423906Israel Department of Urology and Robotic Surgery ICUA-Clínica CEMTROMadrid 28701Spain Urology Division Akfa Medline HospitalTashkent 100211Uzbekistan Advanced Urology Gleneagles HospitalSingapore 258499Singapore Department of Urology National University HospitalSingapore 119228Singapore Divisionof Urology Department of SurgeryUniversity of TorontoOntarioToronto M5G 2C4Canada Department of Urology Mahatma Gandhi Mission’s Medical College and HospitalAurangabad 431003India Institute for Urology and Reproductive Health Sechenov UniversityMoscow119435Russian Federation Department of Urologyand Andrology Lomonosov Moscow State UniversityMoscow 119992Russian Federation Department of Urology Sarvodaya Hospital and Research CentreFaridabadHaryana 121006India Department of Urology Medical University of ViennaVienna 1090Austria Department of Urology Saint-Petersburg State University HospitalSaint-Petersburg 199034Russian Federation Department of Urology Asian Institute of Nephrology and UrologyHyderabad 500082India S.H.Ho UrologyCentre Department of SurgeryFaculty of MedicineThe Chinese University of Hong KongHong Kong 96H2+Q9China Department of Urology University Hospitals Southampton NHS TrustSouthampton SO166YDUnited Kingdom Department of Urology Cantonal Hospital Thurgau AGFraunfeld 8500Switzerland

We aim to evaluate the incidence of incontinence following laser endoscopic enucleation of the prostate(EEP)comparing en-bloc(Group 1)versus 2-lobe/3-lobe techniques(Group 2).We performed a retrospective review of patients undergoing EEP for benign prostaticenlargement in 12 centers between January 2020 and January *** were presented as median and interquartile range(IQR).Univariable and multivariable logistic regression analysis was performed to evaluate factors associated with stress urinary incontinence(SUI)and mixed urinary incontinence(mUI).There were 1711 patients in Group 1 and 3357 patients in Group *** in Group 2were significantly younger(68[62–73]years vs 69[63–74]years,P=0.002).median(interquartile range)prostate volume(PV)wassimilar between the groups(70[52–92]ml in Group 1 vs 70[54–90]ml in Group 2,P=0.774).There was no difference in preoperativeInternational Prostate Symptom Score,quality of life,or maximum flow ***,morcellation,and total surgical time weresignificantly shorter in Group *** 1 month,overall incontinence rate was 6.3%in Group 1 versus 5.3%in Group 2(P=0.12),and urge incontinence was significantly higher in Group 1(55.1%vs 37.3%in Group 2,Pmonths,the overall rate ofincontinence was 1.7%in Group 1 versus 2.3%in Group 2(P=0.06),and SUI was significantly higher in Group 2(55.6%vs 24.1%in Group 1,P=0.002).At multivariable analysis,PV and IPSS were factors significantly associated with higher odds of transient SUI/***,surgical time,and no early apical release technique were factors associated with higher odds of persistent SUI/mUI.

关键词： benign prostatic hyperplasia en-bloc enucleation endoscopic enucleation of the prostate laser therapy stress urinaryincontinence urge urinary incontinence

Asymmetric Patch Element Reflectarray with Dual Linear and Dual Circular Polarization

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Computers, materials & Continua 2022年第12期73卷 6085-6101页

作者： m.Hashim Dahri m.H.Jamaluddin m.inam m.R.kamarudin F.C.Seman A.Y.I.Ashyap Z.A.Shamsan k.Almuhanna F.Alorifi Department of Electronic Engineering Dawood University of Engineering and TechnologyKarachiSindh74800Pakistan Wireless Communication Centre Universiti Teknologi Malaysia81301Johor BahruMalaysia Centre for Telecommunication Research&Innovation(CETRI) Faculty of Electrical and Electronic Engineering TechnologyUniversiti Teknikal Malaysia Melaka(UTeM)Melaka76100Malaysia Faculty of Electrical and Electronic Engineering Universiti Tun Hussein Onn MalaysiaBatu Pahat86400JohorMalaysia Electrical Engineering Department College of EngineeringImam Mohammad Ibn Saud Islamic UniversityRiyadhSaudi Arabia

A reflectarray antenna consisting of asymmetrical patch elements is proposed,which is capable of producing dual linear and dual circular polarized operation at 26GHz *** main purpose of this design is to support four different polarizations using the same patch *** proposed reflectarray has a single layer configuration with a linearly polarized feed and circular ring slots in the ground *** patch element is designed from a square patch element by tilting its one vertical side to some optimized inclination.A wide reflection phase range of 600°is obtained with the asymmetric patch element during unit cell measurements.A 332 element circular aperture reflectarray is designed with the proposed configuration and experimentally validated with a linearly polarized prime feed *** different orientations of mirror and non-mirror asymmetric patch elements on the surface of reflectarray are *** linear polarization is obtained with the mirror orientation of the asymmetric patch elements on the surface of ***,asymmetric patch elements without mirror orientation are demonstrated to produce dual circular polarization with the same linearly polarized feed.A maximum measured gain of 24.4 dB and 26.1 dB is achieved for dual linear and dual circular polarization,*** respective measured efficiencies are 28%and 41.3%,which are supported by amaximum−3 dB gain bandwidth of 13.8%and 11.5%.The circular polarization operation of the reflectarray is also supported by a 6 dB axial ratio bandwidth of 9.2%.The proposed asymmetric patch reflectarray antenna with polarization diversity,wide bandwidth and high gain is suitable to be used in many high frequency applications of 5G communication.

关键词： 5G reflectarray polarization diversity circular polarization

Linearly Polarized millimeter Wave Reflectarray with mutual Coupling Optimization

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Computers, materials & Continua 2022年第8期72卷 2397-2410页

作者： m.inam m.H.Dahri m.R.kamarudin A.Y.I.Ashyap m.H.Jamaluddin N.H.Sulaiman m.A.khan Z.A.Shamsan k.Almuhanna F.Alorifi Centre for Telecommunication Research&Innovation(CETRI) Faculty of Electrical and Electronic Engineering TechnologyUniversiti Teknikal Malaysia Melaka(UTeM)Melaka76100Malaysia Dawood University of Engineering and Technology karachi City Sindh74800Pakistan Faculty of Electrical and Electronic Engineering Universiti Tun Hussein Onn MalaysiaBatu Pahat86400JohorMalaysia Wireless Communication Centre Universiti Teknologi MalaysiaJohor Bahru81301Malaysia Faculty of Computing and Engineering Quest International UniversityIpoh30250PerakMalaysia Balochistan University of Information Technology(FICT) Engineering and Management SciencesQuettaPakistan Electrical Engineering Department College of EngineeringImam Mohammad Ibn Saud Islamic UniversityRiyadhSaudi Arabia

This work provides the design and analysis of a single layer,linearly polarized millimeter wave reflectarray antenna with mutual coupling *** analysis was carried out at 26GHz design frequency using the simulations of the reflectarray unit cells as well as the periodic reflectarray *** simulated results were verified by the scattering parameter and far-fieldmeasurements of the unit cell and periodic arrays,*** agreement between the simulated and measured results was observed in all the *** from the unit cells and reflectarray,the waveguide and horn antenna were also fabricated to be used in the *** measured scattering parameter results of the proposed circular ring unit cells provided a maximum reflection loss of 2.8 dB with phase errors below 10°.On the other hand,the measured far-field results of the 20×20 reflectarray antenna provided a maximum gain of 26.45 dB with a maximum 3 dB beam width of 12°and 1 dB gain drop bandwidth of 13.1%.The performance demonstrated by the proposed reflectarray antenna makes it a potential candidate to be used in modern-day applications such as 5th Generation(5G)and 6th Generation(6G)communication systems.

关键词： Reflectarray millimeter wave antenna mutual coupling antenna measurements

Insulin resistance and adipose tissue interactions as the cornerstone of metabolic(dysfunction)-associated fatty liver disease pathogenesis

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World Journal of Gastroenterology 2023年第25期29卷 3999-4008页

作者： Shreya C pal Nahum méndez-Sánchez Faculty of medicine National Autonomous University of MexicoMexico City 04510Mexico Liver Research Unit Medica Sur Clinic&FoundationMexico City 04510Mexico

The relationship between metabolic derangements and fatty liver development are undeniable,since more than 75% of patients with type 2 diabetes mellitus present with fatty *** is also significant epidemiological association between insulin resistance(IR)and metabolic(dysfunction)-associated fatty liver disease(mAFLD).For little more than 2 years,the nomenclature of fatty liver of non-alcoholic origin has been intended to change to mAFLD by multiple *** a myriad of reasons for which mAFLD is thought to be of metabolic origin could be exposed,the bottom line relies on the role of IR as an initiator and perpetuator of this *** is a reciprocal role in mAFLD development and IR as well as serum glucose concentrations,where increased circulating glucose and insulin result in increased de novo lipogenesis by sterol regulatory elementbinding protein-1c induced lipogenic enzyme stimulation;therefore,increased endogenous production of *** same effect is achieved through impaired suppression of adipose tissue(AT)lipolysis in insulin-resistant states,increasing fatty acid influx into the *** complementary reciprocal situation occurs when liver steatosis alters hepatokine secretion,modifying fatty acid metabolism as well as IR in a variety of tissues,including skeletal muscle,AT,and the *** aim of this review is to discuss the importance of IR and AT interactions in metabolic altered states as perhaps the most important factor in mAFLD pathogenesis.

关键词： metabolic(dysfunction)-associated fatty liver disease Insulin resistance Adipose tissue Fatty liver metabolic syndrome Adipokine

Improved Sequencing Heuristic DSDV Protocol Using Nomadic mobility model for FANETS

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Computers, materials & Continua 2022年第2期70卷 3653-3666页

作者： inam Ullah khan muhammad Abul Hassan muhammad Fayaz Jeonghwan Gwak muhammad Adnan Aziz Department of Electronic Engineering Isra University(SEAS)Islamabad44000Pakistan Department of Computing and Technology Abasyn University Peshawar25000Pakistan Deparment of Computer Engineering Jeju National UniversityJejuKorea Department of Software Korea National University of TransportationChungju27469Korea Department of Biomedical Engineering Korea National University of TransportationChungju27469Korea Department of AI Robotics Engineering Korea National University of TransportationChungju27469Korea Department of IT&Energy Convergence(Bk21 FOUR) Korea National University of TransportationChungju27469Korea

most interesting area is the growing demand of flying-IoT mergers with smart ***,aerial vehicles,especially unmanned aerial vehicles(UAVs),have limited capabilities for maintaining node energy *** order to communicate effectively,IoT is a key element for smart *** improving network performance,routing protocols can be deployed in flying-IoT to improve latency,packet drop rate,packet delivery,power utilization,and average-end-to-end ***,in literature,proposed techniques are verymuch complex which cannot be easily implemented in realworld *** issue leads to the development of lightweight energyefficient routing in flying-IoT *** paper addresses the energy conservation problem in *** paper presents a novel approach for the internet of flying vehicles using DSDV ***-DSDV gives the notion of bellman-ford algorithm consisting of routing updates,information broadcasting,and stale *** shows optimal results in comparison with other contemporary routing *** mobility model is utilized in the scenario of flying networks to check the performance of routing protocols.

关键词： Flying-IoT DSR smart cities UAV’s FANETS