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The Ti-TAN plasmid toolbox for TurboID-based proximity labeling assays in Nicotiana benthamiana

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Journal of Integrative Plant Biology 2024年第2期66卷 166-168页

作者： Huang Tan Yu Zhou Erik Dinius Rosa lozano-Durán Department of Plant Biochemistry Center for Plant MolecularBiology(ZMBP)Eberhard Karls UniversityTubingenD‐72076Germany

Protein-protein interactions and the formation of protein complexes play a central role in the regulation of virtually all aspects of *** identification and characterization of interactions between proteins is the bas... 详细信息

关键词： proximity complexes enable

Exercise benefits meet the esophagus

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Journal of Sport and Health Science 2024年第5期13卷 685-686页

作者： Alejandro Santos-lozano Pedro L.Valenzuela Carmen Fiuza-Luces Alejandro Lucia i+HeALTH European University Miguel de CervantesValladolid 47012Spain Research Institute of the Hospital 12 de Octubre(“imas12”) Madrid 28041Spain Department of Systems Biology University of AlcalaAlcala de Heranes 28801Spain Faculty of Sport Sciences Universidad Europea de MadridVillaviciosa de Odon(Madrid)28670Spain

Gastroesophageal reflux disease(GERD)is defined by recurrent and troublesome heartburn and effortless regurgitation or by the specific complications of this condition—that is,esophagitis,esophageal peptic strictures,and Barrett esophagus.1Although GERD is caused by gastric contents'reaching the esophagus,gastric juices can also reach other anatomical locations(pharynx,mouth,larynx,and airways),leading to(or worsening)extra-esophageal conditions(notably asthma)or symptoms(e.g.,wheezing,cough).1 Together with obesity,GERD is the main risk factor for gastroesophageal malignancies.

关键词： esophagus esophageal Barrett

Chloroplast immunity: A cornerstone of plant defense

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Molecular Plant 2024年第5期17卷 686-688页

作者： Jie Liu Pan Gong Ruobin Lu Rosa lozano-Duran Xueping Zhou Fangfang Li State key Laboratory for Biology of Plant Diseases and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100081China State key Laboratory of Rice Biology Institute of BiotechnologyZhejiang UniversityHangzhouZhejiang 310058China Department of Plant Biochemistry Centre for Plant Molecular Biology(ZMBP)Eberhard Karls UniversityTubingen 72076Germany

Increasing evidence supports the notion that pattern-recognition-receptor-mediated immunity goes beyond plasma membrane-to-nucleus *** the findings of the pathways linking plasma membrane and chloroplasts and the functions of stromules and perinuclear chloroplast clustering(PCC)in plant defense,chloroplast immunity has emerged as a cornerstone of plant defense and a target of plant pathogens.

关键词： plant immunity corners

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由水溶性聚合物制备多功能碳纳米纤维垫

国际纺织导报 2016年第11期44卷 16-18,20页

作者： L.D.Cremar J.Acosta-Martinez A.Villarreal A.Salinas L.Wei Y.B.Mao k.lozano 钟晓慧(译) 王依民(校) 格兰德山谷Texas-Rio大学美国不详

聚合物前驱体成本高、碳化后处理工艺中有机溶剂的应用,以及能源消耗等问题,限制了碳纤维在日常生活中的应用。采用离心力纺丝技术及在酸蒸气中脱水的方法制备非织造纳米纤维垫,并采用低温碳化工艺(t<800℃)制备多功能碳纳米纤维。这种... 详细信息

聚合物前驱体成本高、碳化后处理工艺中有机溶剂的应用,以及能源消耗等问题,限制了碳纤维在日常生活中的应用。采用离心力纺丝技术及在酸蒸气中脱水的方法制备非织造纳米纤维垫,并采用低温碳化工艺(t<800℃)制备多功能碳纳米纤维。这种方法可以制备微孔与中孔的多孔非织造碳纤维织物或纱线。纤维的直径可在几百纳米到几微米之间变化。热物理和微观结构表征表明,化学和热处理过程中的碳化形成了石墨。所制备的纤维表现出较高的导电性和比表面积,以及良好的热稳定性、疏水性和亲油性。

关键词：碳纳米纤维多功能水溶性聚合物离心力纺丝

Hepatic rupture secondary to HELLP syndrome: outcomes in three cases

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World Journal of Emergency Medicine 2024年第1期15卷 56-58页

作者： Salvador Gomez-Carro Ruben R.lozano-Salazar kassandra Santos-Zaldívar Victor Andres Villasuso-Alcocer Nina Méndez-Domínguez O'Horan General Hospital Merida 97000Mexico Highly Specialized Hospital of the Yucatan Peninsula Merida 97134Mexico National Institute of Perinatology.Mexico City 11000 Mexico

Hypertensive disorders of pregnancy,including chronic hypertension,gestational hypertension,and preeclampsia,are the most common complications in pregnant women,affecting approximately 15%of pregnancies.[1,2]Hemolysis,elevated liver enzymes,and low platelet count(HELLP syndrome)can occur in 0.2%-0.6%of all pregnancies,and 10%-15%of patients are diagnosed with preeclampsia.[3,4]Among its severe complications,liver hematoma is remarkable and may lead to liver *** identification of HELLP syndrome is crucial for proper therapeutic management and to avoid fatal outcomes[4,5]since when a hepatic hematoma occurs,the risk of rupture increases to 12%.[3,5]

关键词： rupture HELLP hypertension pregnancy

The Limits of Domestic Spatiality in the Information Age-A Secondary Publication

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Journal of World Architecture 2024年第1期8卷 76-82页

作者： Juan Manuel lozano de Poo Autonomous University of San Luis Potosí San Luis PotosíMexico

The limits of spatiality have blurred in the information age;a phenomenon that can be observed through the socio-spatial implications of Internet use in the domestic *** and why are the use and organization of space-time around the Internet shaping a new domestic spatiality that intertwines the digital space with the production of social space through the practice of habits,presence,and interaction of individuals?What are the repercussions of the superimposition of digital space on human existence?The units of analysis were integrated through the sum of people and middle-class housing in the face of the digitalization process in the city of San Luis Potosi,*** questionnaire consisted of 35 questions designed from the Likert scale under the thematic order of presence,interaction,and *** data were analyzed using SPSS *** research contributes to explaining the current period in the history of inhabitable space,dominated by the simultaneous interrelationships between individuals,digital space,and architecture,which result in the detachment and devaluation of physical domestic space,while also highlighting the lack of control and regulation of individuals over the Internet.

关键词： Graffiti Urban image Legislation Regulations South America

Bloom-forming cyanobacteria and dinoflagellates in five Argentinian reservoirs:Multi-year sampling

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Water Biology and Security 2024年第1期3卷 28-36页

作者： Florencia Soledad Alvarez Dalinger Borja Claudia Nidia Veronica Laura lozano Liliana Beatriz Morana María Monica Salusso Facultad de Ciencias Naturales Universidad Nacional de SaltaAvenida Bolivia 5150Salta4400Argentina Consejo Nacional de Investigaciones Científicas y T'ecnicas(CONICET) Godoy Cruz 2290Ciudad Autonoma de Buenos AiresArgentina

Harmful algal blooms are important threats to reservoir *** a 15-year period,we sampled five Argentinian reservoirs to identify the responsible species for harmful algal blooms and determine the water quality factors driving their *** reservoirs exhibit diverse morphological and hydrological characteristics and are distributed across varying climatic *** blooms included an array of species,including toxin producers such as Raphidiopsis raciborskii,Aphanizomenon gracile,and Microcystis *** contrast,dinoflagellate blooms were predominantly characterized by *** cyanobacterial blooms primarily occurred in the shallower reservoirs located in warmer regions,whereas dinoflagellate blooms occurred where temperatures were *** most intense blooms occurred during the summer,and although cyanobacterial and chlorophyte blooms co-occurred,they never coexisted with dinoflagellate *** identified cyanotoxins in the reservoirs over the past three years,a phenomenon previously unreported in the *** that these reservoirs are drinking water sources for human populations,ongoing and systematic monitoring is needed to protect public *** the proliferation of algae and cyanobacteria in reservoirs requires resource management at the watershed level,and in the case of the Itiyuro and El Limon,requires binational management with Bolivia.

关键词： HABs Freshwater South America Toxins

From Simulation to Reality: A Comprehensive Study on the Efficacy of a Rotating Monopolar and Bipolar Radiofrequency System through In-Silico Modeling and Pre-Clinical and Clinical Validation

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Journal of Biomedical Science and Engineering 2024年第6期17卷 107-128页

作者： Gregorio Viera Mármol Ana Lorena Urbano Bojorge Alicia Robledo Jorge José Antonio Ferrández Martínez Olalla Calvo lozano High Technology Products S.L.U. (Sinclair) Barcelona Spain

Background: Skin aging is an unavoidable process aggravated by environmental agents. Among other energy devices, non-invasive radiofrequency (RF) technology is widely used for skin tightening and body contouring as it is simpler and more affordable than other technologies that also minimize pain and side-effects. However, most of the current RF devices do not provide automatic skin temperature control and it is difficult to achieve controlled, deep, and harmless thermal increase, so treatment performance and safety is dependent on the operator’s movements and expertise. Objective: To show the potential of numerical simulations for optimizing the design of monopolar and bipolar RF electrodes that are capable of providing homogeneous, deep and controlled heating. Materials and methods: In-silico models were developed and analyzed using Comsol Multiphysics software to simulate the RF effect produced in tissue by rotating monopolar and bipolar electrodes with different geometries from the Sculpt & Shape RF device (Sinclair, Spain), operating at frequencies of 0.5 and 1 MHz. Ex-vivo and in-vivo proof-of-concept tests were carried out to validate the simulations. Finally, treatments were performed on 16 subjects and a total of 78 body areas to assess the clinical results generated by the RF electrodes for skin tightening and body contouring. Results: In-silico studies emulated the superficial and deep dispersion of heat due to the release of RF energy into human skin tissue. The rotating electrodes (monopolar and bipolar) and the selected RF frequency (0.5 and 1 MHz) determined the homogeneity of the thermal distribution, the penetration depth (between 4.37 mm and 25.0 mm) and the heating dynamics (between 30 and 100 seconds to reach the target skin temperature), which were confirmed by ex-vivo and in-vivo tests. In addition, real treatments on facial and body areas using skin temperatures of between 43˚C and 44˚C showed consistent results with good clinical efficacy for

关键词： Comsol Multiphysics Simulations Radiofrequency Skin Tightening Fat Reduction Body Contouring Cellulite

Restoring p53 in cancer:the promises and the challenges

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Journal of Molecular Cell Biology 2019年第7期11卷 615-619页

作者： Guillermina lozano Department of Genetics University of Texas MD Anderson Cancer CenterHoustonTX 77030USA

A tribute to Dr Arnold *** This perspective was written in celebration of Dr Arnold ***'s 80th birthday.I chose to write this prospective about restoration of p53 activity in tumors for two reasons:Arnie (as we all know him) has become interested in restoring p53 activity in tumor cells and such a review did not *** was also my postdoctoral advisor and writing this perspective is just a small tribute for the huge impact he has had on my research career (and that of many others),from supporting me when I left his laboratory for a faculty position before I had even published a paper,to serving as a sounding board for numerous ideas.

关键词： tribute written ideas