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Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord

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Neural Regeneration Research 2025年第7期20卷 2095-2107页

作者： Emily A.Hibbard Liwen Zhou Cathy Z.Yang karthik Venkudusamy Yessenia Montoya Alexa Olivarez George d.Bittner dale R.Sengelaub Program in Neuroscience Indiana UniversityBloomingtonINUSA department of Neuroscience University of Texas at AustinAustinTXUSA

Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically *** used a plasmalemmal fusogen,polyethylene glycol(PEG),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic *** have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration,and PEG-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor ***,our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target *** this study,we examined the consequences of PEG-fusion for sensory axons of the sciatic *** adult male and female rats(Sprague–dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of *** action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury *** success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days *** 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish ***-fusion repair reestablished axonal *** to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal ***,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repa

关键词： axotomy dorsal horn peripheral nerve injury plasticity polyethylene glycol(PEG) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase

Enhanced strength in novel nanocomposites prepared by reinforcing graphene in red soil and fly ash bricks

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International Journal of Minerals,Metallurgy and Materials 2019年第10期26卷 1322-1328页

作者： Jit Sarkar d.k.das department of Metallurgical and Materials Engineering Indian Institute of TechnologyKharagpur 721302West BengalIndia department of Mechanical Engineering Indian Institute of Technology(Indian School of Mines)Dhanbad 826004JharkhandIndia

Low-dimensional nanomaterials such as graphene can be used as a reinforcing agent in building materials to enhance the strength and durability. Common building materials burnt red soil bricks and fly ash bricks were reinforced with various amounts of graphene, and the effect of graphene on the strength of these newly developed nanocomposites was studied. The fly ash brick nanocomposite samples were cured as per their standard curing time, and the burnt red soil brick nanocomposite samples were merely dried in the sun instead of being subjected to the traditional heat treatment for days to achieve sufficient strength. The water absorption ability of the fly ash bricks was also discussed. The compressive strength of all of the graphene-reinforced nanocomposite samples was tested, along with that of some standard (without graphene) composite samples with the same dimensions, to evaluate the effects of the addition of various amounts of graphene on the compressive strength of the bricks.

关键词： graphene burnt red soil brick fly ash brick nanocomposites compressive strength

Natural convection flow of a couple stress fluid between two vertical parallel plates with Hall and ion-slip effects

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Acta Mechanica Sinica 2012年第1期28卷 41-50页

作者： d.Srinivasacharya k.kaladhar department of Mathematics National Institute of Technology

The Hall and ion-slip effects on fully developed electrically conducting couple stress fluid flow between vertical parallel plates in the presence of a temperature dependent heat source are investigated. The governing non-linear partial differential equations are transformed into a system of ordinary differential equations using similarity transformations. The resulting equations are then solved using the homotopy analysis method （HAM）. The effects of the magnetic parameter, Hall parameter, ion-slip parameter and couple stress fluid parameter on velocity and temperature are discussed and shown graphically

关键词： Free convection Couple stress fluid Magneto- hydrodynamics Hall and ion-slip effects - HAM

Modelling two-layer nanofluid flow in a micro-channel with electro-osmotic effects by means of Buongiorno’s model

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Applied Mathematics and Mechanics(English Edition) 2020年第1期41卷 83-104页

作者： M.d.k.NIAZI Hang XU State key Lab of Ocean Engineering Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration (CISSE)School of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong University

A fully developed steady immiscible flow of nanofluid in a two-layer microchannel is studied in the presence of electro-kinetic ***’s model is employed for describing the behavior of *** from the previous studies on two-layer channel flow of a nanofluid,the present paper introduces the flux conservation conditions for the nanoparticle volume fraction field,which makes this work new and unique,and it is in coincidence with practical *** governing equations are reduced into a group of ordinary differential equations via appropriate similarity *** highly accurate analytical approximations are *** physical quantities and total entropy generation are analyzed and discussed.A comparison is made to determine the significance of electrical double layer(EdL)effects in the presence of an external electric *** is found that the Brownian diffusion,the thermophoresis diffusion,and the viscosity have significant effects on altering the flow behaviors.

关键词： electrical double layer(EdL) entropy generation micro-channel nanofluid

Effect of Nd^(3+) on spectroscopic properties of lithium borate glasses

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Journal of Rare Earths 2014年第12期32卷 1148-1153页

作者： d.d.Ramteke k.Annapurna V.k.deshpande R.S.Gedam department of Applied Physics Visvesvaraya National Institute of Technology Glass Science and Technology Section CSIR-Central Glass and Ceramic Research Institute

The spectroscopic properties of lithium borate glasses as a function of Nd3＋ ions concentration were *** absorption spectra of these glasses showed a number of absorption bands in ultra violet and visible *** absorption edge was found to shift towards the longer wavelength（red shift） with increase in *** spectra revealed three major bands at 902, 1063 and 1334 nm which was due to 4F3/2→4I9/2, 11/2 ＆13/2 transitions of Nd3＋ *** intensity was maximum for 1 mol.% Nd2O3 and further increase in Nd2O3 resulted in luminescence *** luminescence quenching behavior at higher concentration of Nd2O3 was attributed to the Nd3＋-Nd3＋ interaction in the glass *** absorption and emission property of these glasses suggested that these glasses could be useful for 1.06 μm infrared laser applications.

关键词： glasses optical properties luminescence laser rare earths

Modeling the Contemporary Stress Field and deformation Pattern of Eastern Mediterranean

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Journal of Earth Science 2010年第4期21卷 365-381页

作者： S k dwivedi d Hayashi Simulation Tectonics Laboratory Faculty of ScienceUniversity of the Ryukyus

The contemporary stress field in the earth＇s crust is important and provides insights into mechanisms that drive plate motions. In this study, elastic plane stress finite element modeling incorporating realistic rock parameters was used to calculate the stress field, displacement field, and defor- mation of the plate interactions in the eastern Mediterranean. Modeled stress data for the African- Arabian-Anatolian plate interactions with fixed European platform correlate well with observed contemporary stress indicator from the world stress map （WSM） and focal mechanism of earthquakes; while displacement field agrees qualitatively well with GPS vectors and sense of motion indicated by focal mechanisms for large crustal earthquakes （Ms〉6） and plate motion models. Modeling result shows the direction of maximum horizontal compressive stress （σHmax） toward the direction of absolute motion of these plates. Large perturbations in σHmax orientations are shown to occur in and around tectonic boundaries between those plates. It is observed that, although the African plate acts mostly as indenter, which transmits the collisional motion from the Arabian plate to the Anatolian plate, in the current situation, the far-field stress, probably from the subduction in Aegean Arc, is needed to satisfy the contemporary stress field in Anatolia.

关键词： finite element model maximum horizontal stress seismieity crustal deformation Anatolia eastern Mediterranean.

Machine learning enabled autonomous microstructural characterization in 3d samples

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npj Computational Materials 2020年第1期6卷 1654-1662页

作者： Henry Chan Mathew Cherukara Troy d.Loeffler Badri Narayanan Subramanian k.R.S.Sankaranarayanan Center for Nanoscale Materials Argonne National LaboratoryArgonneILUSA department of Mechanical Engineering University of LouisvilleLouisvilleKYUSA department of Mechanical and Industrial Engineering University of Illinois at ChicagoChicagoILUSA

We introduce an unsupervised machine learning(ML)based technique for the identification and characterization of microstructures in three-dimensional(3d)samples obtained from molecular dynamics simulations,particle tracking data,or *** technique combines topology classification,image processing,and clustering algorithms,and can handle a wide range of microstructure types including grains in polycrystalline materials,voids in porous systems,and structures from self/directed assembly in soft-matter complex *** technique does not require a priori microstructure description of the target system and is insensitive to disorder such as extended defects in polycrystals arising from line and plane *** demonstrate quantitively that our technique provides unbiased microstructural information such as precise quantification of grains and their size distributions in 3d polycrystalline samples,characterizes features such as voids and porosity in 3d polymeric samples and micellar size distribution in 3d complex *** demonstrate the efficacy of our ML approach,we benchmark it against a diverse set of synthetic data samples representing nanocrystalline metals,polymers and complex fluids as well as experimentally published characterization *** technique is computationally efficient and provides a way to quickly identify,track,and quantify complex microstructural features that impact the observed material behavior.

关键词： microstructure polycrystalline porosity

View Creation for Queriesin Object Oriented databases

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Journal of Computer Science & Technology 1999年第4期14卷 349-362页

作者： RajeshNarang k.d.Sharma departmentofComputerScience UniversityofDelhiDelhi110007，I departmentofComputerScience Universityof

A view in object oriented databases corresponds to virtual schemawith restructured generalization and decomposition hierarchies. Numbers of viewcreation methodologies have been proposed. A major drawback of existing method-ologies is that they do not maintain the closure property. That is, the result of aquery does not have the same semantics as embodied in the object oriented datamodel. Therefore, this paper presents a view creation methodology that derives aclass in response to a user's query, integrates derived class in global schema (i.e.,considers the problem of classes moving in class hierarchy) and selects the requiredclasses from global schema to create the view for user's query. Novel idea of viewcreation includes: (a) an object algebra for class derivation and customization (wherethe derived classes in terms of object instances and procedure/methods are studied),(b) maintenance of closure property, and (c) classification algorithm which providesmechanism to deal with the problem of a class moving in a class hierarchy.

关键词： object manipulation type level operation instance level operation,object algebra object operator operator syntax operator semantics derived class,class integration view creation algorithm

3d radiative convective flow of ZnO-SAE50nano-lubricant in presence of varying magnetic field and heterogeneous reactions

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Propulsion and Power Research 2019年第4期8卷 339-350页

作者： M.k.Nayak J.Prakash d.Tripathi V.S.Pandey department of Physics IHSESiksha"O"Anusandhan Deemed to be UniversityBhubaneswar751003OdishaIndia department of Mathematics Avvaiyar Government College for WomenKaraikal609602Puducherry-U.T.India department of Mathematics National Institute of TechnologyUttarakhand246174India department of Physics National Institute of Technology DelhiNew DelhiIndia

A numerical simulation is presented to investigate the effect of an exponentially varying magnetic field on three dimensional flow of Zinc Oxide-Society of Automotive Engineers 50 nanolubricant(ZnO-SAE50nano-lubricant)past a stretching *** the impact of homogenous and heterogeneous reactions on the flow of nanolubricant concerned has also taken into *** study has been strengthened by introducing the convection mechanism and the effect of thermal *** transformations are employed to transform the set of partial governing equations into the set of ordinary differential *** suitable boundary conditions are used to obtain the numerical *** numerical results are simulated using Matlab bvp4c solver and validated with the existing *** flow characteristics,thermal characteristics,nanoparticle concentration and some non-dimensional numbers are computed under the influence of the pertinent *** valuable outcome of the current study is that augmented magnetic field strength is the root cause of diminishing axial as well as transverse velocities and growing trend of fluid ***,the coeffi-cients of homogenous and heterogeneous reactions are boons for ascending concentration boundary layer.

关键词： MHd 3d flow ZnO-SAE50nanolubricant Exponential stretching sheet Convective heating mechanism Thermal radiation Heat generation/absorption