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The effect of downstream resistance on flow diverter treatment of a cerebral aneurysm at a bifurcation: A joint computational-experimental study

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Journal of Hydrodynamics 2018年第5期30卷 803-814页

作者： ANDerson C.O.Tsang Billy Y.S.Yiu Abraham Y.S.Tang w.C.Chung Gilberto k.k.Leung AlexANDer k.k.Poon Alfred C.H.Yu Simon S.M.Lai k.w.chow Department of Surgery Li Ka Shing Faculty of Medicine University of Hong Kong Department of Electrical and Computer Engineering University of Waterloo Department of Mechanical Engineering University of Hong Kong Department of Electrical and Electronic Engineering University of Hong Kong

Intracranial aneurysm can lead to hemorrhagic stroke upon rupture. Deployment of flow diverters can restrict the blood flow into aneurysm and mitigate the rupture risk. Computational fluid dynamics（CFD） and ultrasonography with pulse-wave and color Doppler ultrasound measurements were employed jointly to investigate the complex flow pattern in cerebral aneurysms, both before and after the deployment of flow diverters. Patient-specific configurations of both bifurcation and side-wall aneurysms were selected. The effect of downstream flow resistance was investigated by adjusting the volume flow rate and pressure at the outlet vessels computationally and experimentally. Velocity profiles in the aneurysm measured from ultrasonography showed good agreement with those from computer simulations. The discrepancy in velocity between the computational and experimental sets of data is less than 10%. The downstream resistance can alter the volume flux into a bifurcation aneurysm with a flow diverter deployed by 236%, while the corresponding value of a side-wall aneurysm is negligible. The vorticity of the aneurysmal flow was reduced by more than 80% in both cases after stenting. This study demonstrated that careful investigation of downstream flow resistance of a bifurcation aneurysm is essential to provide an accurate assessment of the aneurysmal flow dynamics after flow diverter deployment.

关键词： Intracranial aneurysms computational fluid dynamics (CFD) doppler ultrasound

Computational Fluid Dynamics Study of a Cardiovascular Disease:Thoracic Aortic Dissection

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Computational Fluid Dynamics Study of a Cardiovascular Disea...

The 16th Annual Conference of Hong kong Society of Theoretical and Applied Mechanics 2012、The 1st Mainland-Hong kong Youth Forum on Mechanics 2012、The 8th Shanghai-Hong kong Forum on Mechanics and Its Application 2012

作者： Y.S.Tang S.k.Lai Stephen w.k.Cheng k.w.chow Department of Mechanical Engineering the University of Hong Kong Department of Surgery the University of Hong Kong

An aortic dissection occurs when blood intrudes into the layers of the vascular wall, creating an artificial *** is a severe pathological situation,since the weakened vessel wall may expand and be subject to the risk of rupture and massive internal bleeding,resulting in high *** is believed that biomechanical factors would play a role in this disease condition. Endovascular repair has now become a frequently employed practice in the clinical treatment and management.A stent graft is deployed to cover the tears and restrict the flow from entering the artificial *** this study,computational fluid dynamics analysis is performed to study the hemodynamics of a dissected aorta(Fig.1).Simplified aortic geometries with realistic dimensions are *** velocity and pressure waveforms are prescribed at the inlet and outlet respectively. Blood flow configuration and biomechanical forces are ***-operation and post-operation conditions are also *** quantitative analysis can provide valuable information for clinicians to making therapeutic decision.

关键词： Computational Fluid Dynamics Study of a Cardiovascular Disease:Thoracic Aortic Dissection

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鱼类配合饵料生产中的质量控制

国外水产 1985年第1期 28-30页

作者： k.w.chow 梁亚全

配合饵料工业中的质量控制不仅包括每一饵料成分经过加工过程变成贮藏品时对质量标准进行的检验,而且包括在整个贮藏期间对各种成分的质量进行严密的监测.质量控制还包括:在混合过程中各种组分的均匀化以及使它们最终变成贮藏品形式的... 详细信息

配合饵料工业中的质量控制不仅包括每一饵料成分经过加工过程变成贮藏品时对质量标准进行的检验,而且包括在整个贮藏期间对各种成分的质量进行严密的监测.质量控制还包括:在混合过程中各种组分的均匀化以及使它们最终变成贮藏品形式的配合饵料.质量控制程序应包括原料、产品和贮藏三个方面.原料发展中国家的食品业比起发达国家来是

关键词：配合饵料最终产品鱼类水生动物质量控制质量管理

A Computational Fluid Dynamics Study on the Endovascular Treatment of Intracranial Aneurysms

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A Computational Fluid Dynamics Study on the Endovascular Tre...

Sungai Lembing’s green tourism: Pioneering the future of resourcebased urban renewal

作者： S.k.Lai Abraham Y.S.Tang k.M.Leung Gilberto k.k.Leung k.w.chow Department of Mechanical Engineering University of Hong Kong Division of Neurosurgery Department of SurgeryLi Ka Shing Faculty of MedicineUniversity of Hong KongQueen Mary Hospital

Intracranial aneurysm,a localized dilation of arterial blood vessels in the brain,is a severe cerebrovascular *** appropriate medical treatment,the rupture of intracranial aneurysms will result in high mortality rate due to excessive bleeding into the cavity surrounding the *** modern technological advances,endovascular stenting technique has now proven to be one effective technique in the clinical management of intracranial *** prime advantage of endovascular intervention over traditional open surgery is that the former procedure is less invasive,and thus a shorter recovery time will *** a mechanical point of view,a metallic stent,serving as a flow diverter,can be deployed to cover the entire aneurysm *** the blood flow inside the aneurysmal sac becomes stagnant,and thrombus formation is likely to *** is expected that a larger extent of thrombosis is capable of reducing the risk of growth and rupture of *** assess this clinical objective quantitatively,we construct a three-dimensional(3D) aneurysm model (see Fig.1) to investigate the blood flow patterns in stented and non-stented *** many idealized models with straight or curved parent blood vessel,the aneurysm of the current model is placed at the bifurcation point of cerebral arteries,a geometric configuration occurring frequently for many *** fluid dynamics techniques are applied to perform the blood flow *** inlet and outlet boundary conditions of this model are subjected to pulsatile velocity and pressure waveforms *** on the present study,the impact of hemodynamic and biomechanical factors on the aneurysm can be *** quantitative findings can also provide valuable information for clinical practitioners to understand and predict the hemodynamic behaviour in patient-specific cases.

关键词： A Computational Fluid Dynamics Study on the Endovascular Treatment of Intracranial Aneurysms

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The Innovation 2024年第3期5卷 19-20页

作者： Haoxuan Yu Ginura Gunaratna Izni Zahidi chow Ming Fai Department of Civil Engineering School of EngineeringMonash University MalaysiaBandar SunwaySelangor 47500Malaysia

HOw DID SUNGAI LEMBING PAVE ITS PATH TO A GREEN EVOLUTION?Sungai Lembing,a resource-based town situated in Pahang,Malaysia,has historically positioned itself as a pivotal hub in the global tin mining ***,Sungai Lembing’s history dates back to the Paleozoic and Mesozoic *** eras were marked by the closure of the Tethyan Ocean and the convergence of continental landmasses from the eastern part of the Gondwana *** complex geological background resulted in a wide variety of mineral resources.

关键词： situated eastern Pioneer

A Dynamic Network Game of the Fintech Industry

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Journal of the Operations Research Society of China 2024年第1期12卷 5-33页

作者： David w.k.Yeung Leon A.Petrosyan Ying-Xuan Zhang SRS Consortium for Advanced Study in Cooperative Dynamic Games Shue Yan UniversityHong KongChina Center of Game Theory St Petersburg State UniversitySaint PetersburgRussia Department of Finance Asia UniversityTaichung CityTaiwanChina Faculty of Applied Mathematics-Control Processes and Center of Game Theory St Petersburg StateUniversitySaint PetersburgRussia

Economies of scale,economies of scope,and technology spillover are decisive eco-nomic elements that are crucial to the development in the Fintech *** externalities are often realized through network *** this paper,we presenta dynamic network ofﬁnancialﬁrms which exhibits these decisive *** game equilibria are characterized.A Pareto efﬁcient solution involving col-laboration of allﬁrms is *** obtain a fair-share distribution of cooperativegains,the Shapley value is adopted as the sharing *** distributionmechanisms which guarantee the fulﬁlment of the Shapley value distribution in eachstage of the cooperation duration are derived.

关键词： Network game Network equilibria Shapley value Pareto efﬁcientcooperation

Detecting fake reviewers in heterogeneous networks of buyers and sellers:a collaborative training-based spammer group algorithm

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Cybersecurity 2024年第2期7卷 44-67页

作者： Qi Zhang Zhixiang Liang Shujuan Ji Benyong Xing Dickson k.w.Chiu Shandong Provincial key Laboratory of wisdom Mine Information Technology Shandong University of Science and TechnologyQingdao 266590ShandongChina Zhejang University-University of linois at Urbana-Champaign Institute Haining 314499ZhejiangChina School of Civil Engineering Beijing Jiaotong UniversityBeijing 100044China Faculty of Education The University of Hong KongPok Fu LamHong KongChina

It is not uncommon for malicious sellers to collude with fake reviewers(also called spammers)to write fake reviews for multiple products to either demote competitors or promote their products'reputations,forming a gray industry *** detect spammer groups in a heterogeneous network with rich semantic information from both buyers and sellers,researchers have conducted extensive research using Frequent Item Mining-based and graph-based ***,these methods cannot detect spammer groups with cross-product attacks and do not jointly consider structural and attribute features,and structure-attribute correlation,resulting in poorer detection ***-fore,we propose a collaborative training-based spammer group detection algorithm by constructing a heterogene-ous induced sub-network based on the target product set to detect cross-product attack spammer *** jointly consider all available features,we use the collaborative training method to learn the feature representations of *** addition,we use the DBSCAN clustering method to generate candidate groups,exclude innocent ones,and rank them to obtain spammer *** experimental results on real-world datasets indicate that the overall detection performance of the proposed method is better than that of the baseline methods.

关键词： Spammer group Heterogeneous network Collaborative training DBSCAN

The magnetosheath at high spectral resolution

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Earth and Planetary Physics 2024年第1期8卷 234-246页

作者： k.D.küntz D.koutroumpa w.R.Dunn A.Foster F.S.Porter D.G.Sibeck B.walsh The Henry A.Rowland Department of Physics and Astronomy Johns Hopkins University3701 San Martin DriveBaltimoreMD21218USA NASA Goddard Space Flight Center 8800 Greenbelt RoadGreenbeltMD 20771USA LATMOS-OVSQ CNRSUVSQ Paris-SaclaySorbonne Université11 Boulevard d’Alembert78280GuyancourtFrance Department of Physics and Astronomy University College LondonLondonUK The Centre for Planetary Science at UCL/Birkbeck Gower StreetLondon WC1E 6BTUK Center for Astrophysics Harvard University&Smithsonian Institution60 Garden StreetCambridgeMA 02138USA Center for Space Physics Boston University110 Cummington MallBostonMAUSA

while we eagerly anticipate SMILE’s(Solar wind Magnetosphere Ionosphere Link Explorer)unprecedented X-ray observations of the Earth’s magnetosheath and the initiation of a new era of magnetospheric research,it seems appropriate to look ahead to the abilities of the next generation of astrophysics *** these,the Line Emission Mapper(LEM),a large aperture micro-calorimeter based mission,is currently planned to be able to observe the magnetosheath at high spectral resolution(~2 eV).with a field of view of~30′,LEM will allow higher spatial resolution and higher cadence measurement of the motion of a very small portion of the magnetopause over relatively short periods of time(multiple hours),complementing SMILE’s global ***’s strength is its spectral *** will be able to measure the abundance of a broad range of elements and ionization states,many of which are inaccessible to current in situ instruments,and will be able to separate the emission from the magnetosheath from the emission from the cosmic X-ray background using the difference in their relative velocities.

关键词： magnetosheath charge exchange solar wind abundances

Reduction of epinephrine in the lumbar spinal cord following repetitive blast-induced traumatic brain injury in rats

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Neural Regeneration Research 2024年第7期19卷 1548-1552页

作者： Shigeharu Tsuda Mustafa Golam Jiamei Hou kevin k.w.wang Floyd J.Thompson Prodip Bose Brain Rehabilitation Research Center Malcom Randall VA Medical CenterNorth Florida/South Georgia Veterans Health SystemGainesvilleFLUSA Department of Anesthesiology College of MedicineUniversity of FloridaGainesvilleFLUSA Department of Emergency Medicine University of FloridaGainesvilleFLUSA Department of Neuroscience University of FloridaGainesvilleFLUSA Department of Neurology University of FloridaGainesvilleFLUSA

Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined the epinephrine level in the central nervous system after traumatic brain *** has been shown to regulate the activities of spinal motoneurons as well as increase the heart rate,blood pressure,and blood flow to the hindlimb ***,the purpose of the present study was to determine the impact of repeated blast-induced traumatic brain injury on the epinephrine levels in seve ral function-s pecific central nervous system regions in *** three repeated blast injuries at 3-day intervals,the hippocampus,motor cortex,locus coeruleus,vestibular nuclei,and lumbar spinal cord were harvested at post-injury day eight and processed for epinephrine assays using a high-sensitive electrochemical detector cou pled with high-performance liquid *** results showed that the epinephrine levels were significantly decreased in the lumbar spinal cord tissues of blast-induced traumatic brain injury animals compared to the levels detected in age-and sex-matched sham *** other function-specific central nervous system regions,although the epinephrine levels were slightly altered following blast-induced tra u matic brain injury,they were not statistically *** results suggest that blast injury-induced significant downregulation of epinephrine in the lumbar spinal cord could negatively impact the motor and cardiovascular *** is the first repo rt to show altered epinephrine levels in the spinal cord following repetitive mild blast-induced traumatic brain injury.

关键词： balance blood flow cardiovascular system central nervous system epinephrine ischemic damage lumbar spinal cord muscle tone repeated blast spasticity traumatic brain injury