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Turbulent hydrodynamics experiments in high energy density plasmas： scientific case and preliminary results of the TurboHEdp project

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High power Laser Science and Engineering 2018年第3期6卷 50-64页

作者： A. Casner G. Rigon B. Albertazzi Th. Michel T. pikuz A. Faenov p. Mabey N. Ozaki Y. Sakawa T. Sano J. Ballet p. Tzeferacos d. Lamb E. Falize G. Gregori M. koenig Universite de Bordeaux-CNRS-CEA CELIA (CEntre Lasers Intenses et Applications) UMR 5107 F-33405 Talence France LULi- CNRS Ecole Polytechnique CEA Universite Paris-Saclay UPMC Univ Paris 06 : Sorbonne Universites -F-91128 Palaiseau cedex France ENS Lyon Universite de Lyon CHELS 69342 Lyon France Open and Transdisciplinary Research initiatives Osaka University Suita Osaka 565-0871 Japan Joint institute for High Temperature RAS Moscow 125412 Russia Graduate School of Engineering Osaka University Suita Osaka 565-0871 Japan institute of Laser Engineering Osaka University Suita Osaka 565-0871 Japan Laboratoire AiM CEA-IRFU/CNRS/Universite Paris Diderot Departement d'Astrophysique CEA Saclay F-91191 Gif sur Yvette France Flash Center for Computational Science University of Chicago USA CEA DAM DIF F-91297 Arpajon France Clarendon Laboratory University of Oxford Parks Road Oxford OX1 3PU UK

The physics of compressible turbulence in high energy density(HEd) plasmas is an unchartered experimental *** of compressible and radiative flows relevant for astrophysics rely mainly on subscale parameters. Therefore,we plan to perform turbulent hydrodynamics experiments in HEd plasmas(TurboHEdp) in order to improve our understanding of such important phenomena for interest in both communities: laser plasma physics and astrophysics. We will focus on the physics of supernovae remnants which are complex structures subject to fluid instabilities such as the Rayleigh–Taylor and kelvin–Helmholtz instabilities. The advent of megajoule laser facilities, like the National ignition Facility and the Laser Megajoule, creates novel opportunities in laboratory astrophysics, as it provides unique platforms to study turbulent mixing flows in HEd plasmas. indeed, the physics requires accelerating targets over larger distances and longer time periods than previously achieved. in a preparatory phase, scaling from experiments at lower laser energies is used to guarantee the performance of future MJ experiments. This subscale experiments allow us to develop experimental skills and numerical tools in this new field of research, and are stepping stones to achieve our objectives on larger laser facilities. We review first in this paper recent advances in high energy density experiments devoted to laboratory astrophysics. Then we describe the necessary steps forward to commission an experimental platform devoted to turbulent hydrodynamics on a megajoule laser facility. Recent novel experimental results acquired on LULi2000, as well as supporting radiative hydrodynamics simulations, are presented. Together with the development of LiF detectors as transformative X-ray diagnostics, these preliminary results are promising on the way to achieve micrometric spatial resolution in turbulent HEd physics experiments in the near future.

关键词：高能密度湍流物理激光技术发展现状

preparation of some new arylseleno compounds and application in the oxidation of olefins

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Chinese Journal of Chemistry 1990年第3期8卷 274-280页

作者： BARTON d.H.R MiLLiET p. LUSiNCHi X. department of Chemistry Texas A.& M.UniversityCollege StationTexas 77843U.S.A. institut de Chimie des Substances Naturelles C.N.R.S.91190 Gif-sur-YvetteFrance

Fifteen pyridine and substituted benzene diselenides,seleninic acids and seleninic anhydrides have been *** them,4,4'-dipyridinediselenide,bis(2,4-dimethoxyphenyl)diselenide, 2,4-dimethoxyphenyl seleninic acid,2-pyridineseleninic acid,2-pyridineseleninic anhydride,4-pyridine- seleninic anhydride,2-nitrophenyl seleninic anhydride and 4-nitrophenyl seleninic anhydride were new *** regioselective oxidation or dehydrogenation of β-pinene,3β-benzoyloxycholest- 5-ene and androstan-3-one have been studied and compared.2-pyridineseleninic anhydride is a more efficient oxidant than the others;most of the substituted benzeneseleno derivatives did not give the expected products.

关键词： preparation of some new arylseleno compounds and application in the oxidation of olefins

involvement of Met receptor pathway in aggressive behavior of colorectal cancer cells induced by parathyroid hormone-related peptide

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World Journal of Gastroenterology 2022年第26期28卷 3177-3200页

作者： María Belén Novoa díaz pedro Carriere Graciela Gigola Ariel Osvaldo Zwenger Natalia Calvo Claudia Gentili departamento de Biología Bioquímica y FarmaciaUniversidad Nacional del Sur(UNS)-INBIOSUR(CONICET-UNS)Bahía Blanca 8000Buenos AiresArgentina Centro de Estudios Clínicos SAGA CEC SAGASantiago de Chile 8320000Chile

BACkGROUNd parathyroid hormone-related peptide(pTHrp)plays a key role in the development and progression of many *** found that in colorectal cancer(CRC)HCT116 cells,the binding of pTHrp to its receptor pTHR type 1(pTHR1)activates events associated with an aggressive *** HCT116 cell xenografts,pTHrp modulates the expression of molecular markers linked to tumor *** evidence suggests that the Met receptor is involved in the development and evolution of *** on these data,we hypothesized that the signaling pathway trigged by pTHrp could be involved in the transactivation of Met and consequently in the aggressive behavior of CRC *** To elucidate the relationship among pTHR1,pTHrp,and Met in CRC *** For in vitro assays,HCT116 and Caco-2 cells derived from human CRC were incubated in the absence or presence of pTHrp(1-34)(10-8 M).Where indicated,cells were pre-incubated with specific kinase inhibitors or dimethylsulfoxide,the vehicle of the *** protein levels were evaluated by Western blot ***-time polymerase chain reaction(RT-qpCR)was carried out to determine the changes in gene *** healing assay and morpho logical monitoring were performed to evaluate cell migration and changes related to the epithelialmesenchymal transition(EMT),*** number of viable HCT116 cells was counted by trypan blue dye exclusion test to evaluate the effects of irinotecan(CpT-11),oxaliplatin(OXA),or doxorubicin(dOXO)with or without *** in vivo tests,HCT116 cell xenografts on 6-wk-old male N:NiH(S)_nu mice received daily intratumoral injections of pTHrp(40μg/kg)in 100μL phosphate-buffered saline(pBS)or the vehicle(pBS)as a control during 20 *** slaughter was carried out and the tumors were removed,weighed,and fixed in a 4%formaldehyde solution for subsequent treatment by *** evaluate the expression of molecular markers in human tumor samples,we studied 23 specimens ob

关键词： pTHrp MET receptor tyrosine kinase parathyroid hormone receptor type 1 Colorectal cancer drug resistance

in vitro antiplasmodial activity of crude extracts from Togolese medicinal plants

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Asian pacific Journal of Tropical Medicine 2011年第2期4卷 129-132页

作者： koffi koudouvo Simplice d.karou denise p.ilboudo kouami kokou kodjo Essien kodjo Aklikokou Comlan de Souza Jacques Simpore Mensavi Gbeassor Centre de Recherche et de Formation sur les plantes Medicinales(CERFOpLAM) Universite de LomeTogo Laboratoire de Botanique et d'Ecologie Vegetale Faculte des SciencesUniversite de LomeTogo Centre de recherche Biomoleculaire pietro Annigoni(CERBA) OuagadougouBurkina Faso

Objective:To investigate the antimalarial effect of a few plants in Togo folk medicine. Methods:After ethnobotanical survey,Opilia celtidifolia,pavetta corymbosa（***） and Tamarindus indica（***） were selected for *** vitro antimalarial tests were performed on crude extracts against fresh clinical isolates of plasmodium falciparum using the semi ***:different iC50,values of the extracts ranged from 2.042 to 100.000μg/mL. According to the results,the methanol extract of aerial part of *** followed by aqueous extract of fruit of *** were the most active(iC50 of 2.042 and 4.786μg/mL,respectively). Qualitative test revealed the presence of alkaloids in the leaves of *** that may be responsible for the activity of the ***:Our study provides scientific evidence for usage of plant in the folk medicine,and further studies are needed for identification and purification of the active principles.

关键词： Medicinal plants in vitro Screening plasmodium falciparum

缓蚀离子存在条件下阳极氧化提高Ti-6Al-4V合金的耐蚀性

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Transactions of Nonferrous Metals Society of China 2022年第6期32卷 1896-1909页

作者： A.L.MARTiNEZ d.O.FLAMiNi S.B.SAidMAN instituto de ingeniería Electroquímica y Corrosión(iNiEC) Departamento de Ingeniería Química(DIQ)Universidad Nacional del Sur(UNS)Argentina Consejo Nacional de investigaciones Científicas y Técnicas(CONiCET) Bahía BlancaArgentina

通过恒电流阳极氧化在Ti−6Al−4V合金表面制备彩色氧化物薄膜。采用3种不同的含有腐蚀无机缓蚀剂的水溶液(Na_(2)MoO_(4),NaH_(2)pO_(4)和NH_(4)VO_(3))进行阳极化处理,研究缓蚀剂阴离子对合金在Ringer溶液中腐蚀行为的影响。采用开路电... 详细信息

通过恒电流阳极氧化在Ti−6Al−4V合金表面制备彩色氧化物薄膜。采用3种不同的含有腐蚀无机缓蚀剂的水溶液(Na_(2)MoO_(4),NaH_(2)pO_(4)和NH_(4)VO_(3))进行阳极化处理,研究缓蚀剂阴离子对合金在Ringer溶液中腐蚀行为的影响。采用开路电位(OCp)、Tafel极化、线性扫描伏安(LSV)和计时电流(CA)等手段,评估处理后电极的腐蚀性能。通过释放的Mo、V和p,采用iCp-AES技术检测缓蚀剂离子的掺入。利用扫描电子显微镜(SEM)、X射线衍射(XRd)和X射线光电子能谱(XpS)对形成的氧化物进行表征。结果表明,无论采用何种溶液,均获得无孔或裂纹的致密无定形氧化物。在Na_(2)MoO_(4)溶液中阳极氧化样品的腐蚀电流密度最低(0.11μA/cm^(2)),即使在Ringer溶液中浸泡168 h,仍能保护合金,而未检测到裂纹或腐蚀产物。XpS分析结果显示,钼以Mo^(6+)和Mo^(4+)的形式掺入氧化膜中。

关键词： Ti−6Al−4V合金阳极氧化无机缓蚀剂腐蚀防护

Energy calibration of HpGe detector using the high-energy characteristic γ rays in 13C formed in 6Li + 12C reaction

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Nuclear Science and Techniques 2020年第5期31卷 57-63页

作者： Jia-Tai Li Xue-dou Su Gao-Long Zhang Guang-Xin Zhang Shi-peng Hu Jing-Bin Lu Yi-Feng Lv Hui-Bin Sun Huan-Qiao Zhang d.Testov p.R.John J.J.Valiente-dobon A.Goasduff M.Siciliano F.Galtarossa F.Recchia d.Mengoni d.Bazzacco School of physics Beihang UniversityBeijing 100191China Shenyuan Honors College Beihang UniversityBeijing 100191China Beijing Advanced innovation Center for Big data-Based precision Medicine School of Medicine and EngineeringBeihang University and Key Laboratory of Big Data-Based Precision Medicine(Beihang University)Ministry of Industry and Information TechnologyBeihang UniversityBeijing 100191China dipartimento di Fisica Astronomia dell’Universit'a di PadovaPaduaItaly istituto Nazionale di Fisica Nucleare Sezione di PadovaPaduaItaly College of physics Science and Technology Shenzhen UniversityShenzhen 518060China College of physics Jilin UniversityChangChun 130012China China institute of Atomic Energy Beijing 102413China Laboratori Nazionali di Legnaro INFNLegnaroPaduaItaly irfu/CEA Universit de Paris-SaclayGif-sur-YvetteFrance

An 6 Li+89Y experiment was conducted at the Laboratori Nazinali di Legnaro,iNFN,*** 550μg/cm^2 thick^89Y target was backed on a 340μg/cm^2 thick 12C *** severalγrays in the experiment with energies higher than 3000 keV can most likely be ascribed to the transitions in the 13C nuclei,which can be formed through various interactions between the 6 Li beam and the 12C *** high-energy properties ofγrays in 13C are employed for energy calibrating HpGe detectors,especially for the>3000 keV region,which is impossible to reach by common standard sources(152Eu,133Ba,etc.).Furthermore,γ-γand particle-γcoincidence measurements were performed to investigate the formation of 13C.

关键词： Energy calibration Coincidence measurement Weakly bound nuclei Reaction mechanism

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Chinese physics C 2014年第9期38卷 1-4页

作者： k.A.Olive k.Agashe C.Amsler M.Antonelli J.-F.Arguin d.M.Asner H.Baer H.R.Band R.M.Barnett T.Basaglia C.W.Bauer J.J.Beatty V.i.Belousov J.Beringer G.Bernardi S.Bethke H.Bichsel O.Biebe E.Blucher S.Blusk G.Brooijmans O.Buchmueller V.Burkert M.A.Bychkov R.N.Cahn M.Carena A.Ceccucci A.Cerr d.Chakraborty M.-C.Chen R.S.Chivukula k.Copic G.Cowan O.dahl G.d'Ambrosio T.damour d.de Florian A.de Gouvea T.deGrand p.de Jong G.dissertor B.A.dobrescu M.doser M.drees H.k.dreiner d.A.Edwards S.Eidelman J.Erler V.V.Ezhela W.Fetscher B.d.Fields B.Foster A.Freitas T.k.Gaisser H.Gallagher L.Garren H.-J.Gerber G.Gerbier T.Gershon T.Gherghetta S.Golwala M.Goodman C.Grab A.V.Gritsan C.Grojean d.E.Groom M.Grnewald A.Gurtu T.Gutsche H.E.Haber k.Hagiwara C.Hanhart S.Hashimoto Y.Hayato k.G.Hayes M.Heffner B.Heltsley J.J.Hernandez-Rey k.Hikasa A.Hocker J.Holder A.Holtkamp J.Huston J.d.Jackson k.F.Johnson T.Junk M.kado d.karlen U.F.katz S.R.klein E.klempt R.V.kowalewski F.krauss M.kreps B.krusche Yu.V.kuyanov Y.kwon O.Lahav J.Laiho p.Langacker A.Liddle Z.Ligeti C.-J.Lin T.M.Liss L.Littenberg k.S.Lugovsky S.B.Lugovsky F.Maltoni T.Mannel A.V.Manohar W.J.Marciano A.d.Martin A.Masoni J.Matthews d.Milstead p.Molaro k.Monig F.Moortgat M.J.Mortonson H.Murayama k.Nakamura M.Narain p.Nason S.Navas M.Neubert p.Nevski Y.Nir L.pape J.parsons C.patrignani J.A.peacock M.pennington S.T.petcov kavli ipMU A.piepke A.pomarol A.Quadt S.Raby J.Rademacker G.Raffel B.N.Ratcliff p.Richardson A.Ringwald S.Roesler S.Rolli A.Romaniouk L.J.Rosenberg J L.Rosner G.Rybka C.T.Sachrajda Y.Sakai G.p.Salam S.Sarkar F.Sauli O.Schneider k.Scholberg d.Scott V.Sharma S.R.Sharpe M.Silari T.Sjostrand p.Skands J.G.Smith G.F.Smoot S.Spanier H.Spieler C.Spiering A.Stahl T.Stanev S.L.Stone T.Sumiyoshi M.J.Syphers F.Takahashi M.Tanabashi J.Terning L.Tiator M.Titov N.p.Tkachenko N.A.Tornqvist d.Tovey G.Valencia G.Venanzoni M.G.Vincter p.Vogel A.Vogt S.p.Wakely W.Walkowiak C.W.Walter d.R.Ward G.Weiglein d.H.Weinberg E.J.Weinberg M.White L.R.Wiencke C.G.Wohl L.Wolfenstein J.Womersley C.L. University of Minnesota School of Physics and Astronomy116 Church St.S.E.MinneapolisMN 55455USA University of Maryland Department of PhysicsCollege ParkMD 20742-4111USA Albert Einstein Center for Fundamental physics Universitat BernCH-3012 BernSwitzerland Lab.Nazionali di Frascati dell'iNFN CP 13via E.Fermi40I-00044 Frascati(Roma)Italy departement de physique Universite de MontrealC.P.6128succ.centre-villeMontreal(Quebec) H3C 3J7Canada pacific Northwest National Laboratory 902 Battelle BoulevardRichlandWA 99352USA department of physics and Astronomy University of OklahomaNormanOK 73019USA department of physics University of WisconsinMadisonWI 53706USA physics division Lawrence Berkeley National Laboratory1 Cyclotron RoadBerkeleyCA 94720USA CERN European Organization for Nuclear ResearchCH-1211 Geneve 23Switzerland department of physics The Ohio State University191 W.Woodruff Ave.ColumbusOH 43210 COMpAS Group Institute for High Energy PhysicsRU- 142284ProtvinoRussia LpNHE IN2P3-CNRS et Universites de Paris 6 et 7F-75252 ParisFrance Max-planck-institute of physics 80805 MunichGermany department of physics University of WashingtonSeattleWA 98195USA Ludwig-Maximilians-Universitat Fakultdt für PhysikSchellingstr.4D-80799 MünchenGermany Enrico Fermi institute and department of physics University of ChicagoChicagoIL 60637-1433USA department of physics Syracuse UniversitySyracuseNY13244USA department of physics Columbia University538 W.120th StreetNew YorkNY10027 USA High Energy physics Group Blackett LaboratoryImperial CollegePrince Consort RoadLondon SW7 2AZUK Jefferson Lab 12000 Jefferson Ave.Newport NewsVA 23606USA department of physics University of VirginiaPO Box 400714CharlottesvilleVA 22904USA Fermi National Accelerator Laboratory P.O.Box 500BataviaIL 60510USA kavli institute for Cosmological physics University of ChicagoChicagoIL 60637-1433USA department of physics and Astronomy University of SussexFalmerBrighton BN1 9QHUK department o

The Review summarizes much of particle physics and cosmology. Using data from previous editions, plus 3,283 new measurements from 899 papers, we list, evaluate, and average measured properties of gauge bosons and the recently discovered Higgs boson, leptons, quarks, mesons, and baryons. We summarize searches for hypothetical particles such as heavy neutrinos, supersymmetric and technicolor particles, axions, dark photons, etc. All the particle properties and search limits are listed in Summary Tables. We also give numerous tables, figures, formulae, and reviews of topics such as Supersymmetry, Extra dimensions, particle detectors, probability, and Statistics. Among the 112 reviews are many that are new or heavily revised including those on： dark Energy, Higgs Boson physics, Electroweak Model, Neutrino Cross Section Measurements, Monte Carlo Neutrino Generators, Top Quark, dark Matter, dynamical Electroweak Symmetry Breaking, Accelerator physics of Colliders, High-Energy Collider parameters, Big Bang Nucleosynthesis, Astrophysical Constants and Cosmological parameters. A booklet is available containing the Summary Tables and abbreviated versions of some of the other sections of this full Review. All tables, listings, and reviews （and errata） are also available on the particle data Group website： http ：//pdg. lbl. gov.

关键词： REViEW OF pARTiCLE pHYSiCS

importance of Quercus *** diversity and biomass of vascular epiphytes in a managed pine-oak forest in Southern Mexico

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Forest Ecosystems 2022年第3期9卷 366-377页

作者： Nayely Martínez-Meléndez Neptalí Ramírez-Marcial José G. García-Franco Manuel Jesús Cach-pérez pablo Martínez-Zurimendi departamento de Conservacion de la Biodiversidad El Colegio de la Frontera Sur(ECOSUR)San Cristobal de Las Casas29290ChiapasMexico Red de Ecología Functional Instituto de EcologíaA.C.Xalapa91073VeracruzMexico departamento de Agricultura Sociedad y AmbienteEl Colegio de la Frontera Sur(ECOSUR)Villahermosa86280TabascoMexico

Background:Forestry management modifies the diversity,structure,and functioning of intervened *** extraction reduces tree density and basal area,leading to changes in the communities of vascular *** objective of this study was to evaluate the diversity and biomass of vascular epiphytes in Quercus trees remaining in two pine-oak forest stands that have been subjected to two stages of the Silvicultural development Method(release cutting,and thinning)in comparison with an unharvested old-secondary forest in southern *** each treatment,richness of epiphytes present on 60 oak trees was recorded and their dry biomass *** calculated the true diversity(Hill numbers)and beta diversity using the Jaccard coefficient of similarity,and generated rank abundance curves per taxonomic epiphyte group(bromeliads,orchids,ferns and others).For each treatment,the relationships between overall diversity and epiphyte biomass to the host trees basal area were analyzed using log linear ***:We recorded a total of 67 species of epiphytes species belonging to 10 families hosted by five species of *** greatest species richness(^(0)d)was recorded in the old-secondary *** common(^(1)d)and dominant(^(2)d)species were recorded in the release cutting than in the other *** diversity and biomass were both slightly related to host tree basal *** of epiphytes was similar(60%)among treatments,although orchids,bromeliads,and other families were more diverse in the old-secondary *** bromeliad species were shared across all treatments,although orchids presented the most exclusive species in the unharvested *** bromeliad Tillandsia seleriana provided the greatest contribution to biomass in all treatments,followed by the orchid Camaridium *** linear models indicated that epiphyte diversity was significantly related to treatment,and epiphyte biomass to basal area of host ***:Alt

关键词： Bromeliads Chiapas Ferns Orchids Richness Sierra Madre Silvicultural development method(SdM)

Human endogenous retroviruses: ammunition for myeloid cells in neurodegenerative diseases?

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Neural Regeneration Research 2020年第6期15卷 1043-1044页

作者： Joel Gruchot david kremer patrick küry department of Neurology NeuroregenerationMedical FacultyHeinrich-Heine-University

Activation of myeloid cells by human endogenous retroviral entities:While the exact causes of neurological diseases such as multiple sclerosis(MS)or amyotrophic lateral sclerosis(ALS)are still elusive,there is evidence of a new category of pathogenic elements called human endogenous retroviruses(HERVs)which seem to contribute to their evolution and progression by exerting inflammatory and degenerative effects(kury et al.,2018).HERVs are ancient retroviral elements which account for up to 8%of the human genome and it is known that environmental factors can trigger their(re-)expression(kury et al.,2018).The resulting production of viral particles and/or proteins,especially from members of the HERV-W and HERV-k family,is strongly correlated with the onset and progression of neurological diseases,such as MS and ALS(kury et al.,2018).

关键词： endogenous diseases al.