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Effect of desiccation on viability and biochemical changes in knema attenuata seeds

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Journal of Forestry research 2012年第4期23卷 703-706页

作者： Vinayachandra Chandrashek.r.k.r. Department of Applied Botany Mangalore UniversityMangalagangothri-574199MangaloreKarnatakaIndia

We studied effect of desiccation on knema attenuata seeds in the laboratory conditions （28 ± 2℃） for 8 days. We also monitored biochemical changes during germination by following standard procedures. Seeds lost their viability in 8 days by decreasing to 18% of moisture content from its original value of 31%. The total sugar, protein and lipid contents decreased during seed ageing. An increase was noticed in the protease activity during desiccation. The phenolic content in seed exudates was increased during ageing. The result confirms the degradation of stored biomolecules in seeds during ageing. Desiccation sensitiv- ity and biochemical changes during dehydration confirm its recalcitrant nature.

关键词： ageing biochemical changes biomolecules germination knema attenuata moisture content

Terminalia arjuna bark extract attenuates picrotoxin-induced behavioral changes by activation of serotonergic,dopaminergic,GABAergic and antioxidant systems

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Chinese Journal of Natural Medicines 2017年第8期15卷 584-596页

作者： Chandra Sekhar Y Phani kumar G Anilakumar k.r. Applied Nutrition Division Defence Food Research LaboratoryDRDOMysore-570011KarnatakaIndia

Stress and emotion are associated with several illnesses from headaches to heart diseases and immune deficiencies to central nervous system. Terminalia arjuna has been referred as traditional Indian medicine for several ailments. The present study aimed to elucidate the effect of T. arjuna bark extract(TA) against picrotoxin-induced anxiety. Forty two male Balb/c mice were randomly divided into six experimental groups(n = 7): control, diazepam(1.5 mg·kg^(–1)), picrotoxin(1 mg·kg^(–1)) and three TA treatemt groups(25, 50, and 100 mg/kg). Behavioral paradigms and PCr studies were performed to determine the effect of TA against picrotoxin-induced anxiety. The results showed that TA supplementation increased locomotion towards open arm(EPM) and illuminated area(light-dark box test), and increased rearing frequency(open field test) in a dose dependent manner, compared to picrotoxin(P rthermore, TA increased number of licks and shocks in Vogel's conflict. PCr studies showed an up-regulation of several genes, such as BDNF, IP_3, D_2L, CrEB, GABAA, SOD, GPx, and Gr in TA administered groups. In conclusion, alcoholic extract of TA bark showed protective activity against picrotoxin in mice by modulation of genes related to synaptic plasticity, neurotransmitters, and antioxidant enzymes.

关键词： Anxiety Terminalia arjuna Gene expression Picrotoxin Neurotransmitters LC-MS

Psychosocial interventions for infertile couples:A scoping review

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Asian pacific Journal of reproduction 2024年第3期13卷 97-106页

作者： Sreemol Sunil Anish k.r. rajagiri College of Social Sciences KalamasseryKeralaIndia

Objective:To bring out current evidence regarding psycho-social interventions for infertility care,and identify the best practices in clinical ***:An in-depth literature review on infertility care intervention was conducted using data from multiple databases:PubMed,EMBASE,Google Scholar,and *** relevant articles selected were between 2008 and ***:A literature search turned up 1798 citations,of which 25 studies were included after rigorous *** intervention categories have been constantly utilised to provide support and promote mental health,of which acceptance and commitment therapy(ACT)and cognitive behaviour therapy(CBT)were used most *** interventions exhibited diversity in both content and composition,and addressed a wide range of ***:The review emphasizes that psycho-social interventions have a positive effect on psychological issues,relationships,and pregnancies among couples and can be incorporated into fertility-care practices.

关键词： Infertile couples Psychosocial interventions Mental health Quality of life

Coarse to Fine: The role of Severe Plastic Deformation in Advancing Titanium-Based Medical Implants - A Comprehensive review

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Journal of Wuhan University of Technology(Materials Science) 2025年第1期40卷 295-306页

作者： Dragana r Mihajlović Bojan I Međo Ivana Lj Cvijović-Alagić Veljko r Djokić Faculty of Technology and Metallurgy University of BelgradeKarnegijeva 411120 BelgradeSerbia Vinča Institute of Nuclear Sci-ences-National Institute of the republic of Serbia University of Belgrade11001BeogradSerbia Innovation Centre of the Faculty of Technology and Metallurgy Karnegijeva 411120 BelgradeSerbia

This paper describes severe plastic deformation(SPD)procedures,which are utilized to form an ultrafine-grained structure in metallic *** the SPD process,a solid material sample is subjected to very high loads without a significant change in sample *** the present work,the high-pressure torsion(HPT)process,as one of the SPD techniques,which achieves a high degree of deformation and ensures refinement of the microstructure,will be discussed in more *** that grain size control is accepted as a method to obtain materials with desired characteristics,an overview of the properties of ultrafine-grained titanium-based biomaterials to be used in medicine is ***,particular attention is dedicated to the influences of HPT process parameters,primarily hydrostatic pressure,and number of revolutions during torsion,on the grain size and physical and mechanical characteristics(modulus of elasticity,microhardness,and tensile properties),corrosion resistance,and biocompatibility of the titanium-based biomaterials.A review of the literature indicates that titanium-based materials obtained by the SPD process show improved mechanical and physical properties without losing biocompatibility and corrosion resistance,which suggests that these methods of obtaining implants are something that should be further developed in the future.

关键词： high-pressure torsion process ultrafine-grained titanium-based materials electrochemical anodization physical properties mechanical properties

前瞻性和回顾性心电门控冠状动脉64层CT成像:影像质量和病人放射剂量的对照性研究

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国际医学放射学杂志 2008年第5期31卷 400-400页

作者： W.P. Shuman k.r. branch J.M. May L.M. Mitsumori D.W. Lockhart T.J.Dubinsky 邱建星（译）唐光健（校） Department of radiology University of Washington School of Medicine 1959 NE Pacific St Seattle WA 98195USA. 不详

目的比较一组接受前瞻性心电门控64层CT冠状动脉成像病人及另一组接受回顾性心电门控64层CT冠状动脉病人的成像质量及病人放射剂量。方法本研究依从HIPAA法案并得到了机构审查委员会的批准。由于设计是回顾性研究故不需要知情同意。2位... 详细信息

目的比较一组接受前瞻性心电门控64层CT冠状动脉成像病人及另一组接受回顾性心电门控64层CT冠状动脉病人的成像质量及病人放射剂量。方法本研究依从HIPAA法案并得到了机构审查委员会的批准。由于设计是回顾性研究故不需要知情同意。2位独立阅片者分别对100例病人心脏CT成像（每组各50例）的冠状动脉进行分段影像质量评分和综合评分。计算观察者间偏差。记录对应实际扫描Z轴长度的病人放射剂量，以Z轴长度为12cm的典型心脏计算标准化剂量。结果2组病例的临床特征及CT参数匹配良好。

关键词：回顾性心电门控冠状动脉病放射剂量 CT成像影像质量 64层CT 冠状动脉成像质量评分

Intrumer:A Multi Module Distributed Explainable IDS/IPS for Securing Cloud Environment

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Computers, Materials & Continua 2025年第1期82卷 579-607页

作者： Nazreen Banu A S.k.B.Sangeetha Department of Computer Science and Engineering SRM Institute of Science and TechnologyVadapalani CampusChennai600026Tamil NaduIndia

The increasing use of cloud-based devices has reached the critical point of cybersecurity and unwanted network *** environments pose significant challenges in maintaining privacy and *** approaches,such as IDS,have been developed to tackle these ***,most conventional Intrusion Detection System(IDS)models struggle with unseen cyberattacks and complex high-dimensional *** fact,this paper introduces the idea of a novel distributed explainable and heterogeneous transformer-based intrusion detection system,named INTrUMEr,which offers balanced accuracy,reliability,and security in cloud settings bymultiplemodulesworking together within *** traffic captured from cloud devices is first passed to the TC&TM module in which the Falcon Optimization Algorithm optimizes the feature selection process,and Naie Bayes algorithm performs the classification of *** selected features are classified further and are forwarded to the Heterogeneous Attention Transformer(HAT)*** this module,the contextual interactions of the network traffic are taken into account to classify them as normal or malicious *** classified results are further analyzed by the Explainable Prevention Module(XPM)to ensure trustworthiness by providing interpretable *** the explanations fromthe classifier,emergency alarms are transmitted to nearby IDSmodules,servers,and underlying cloud devices for the enhancement of preventive *** experiments on benchmark IDS datasets CICIDS 2017,Honeypots,and NSL-kDD were conducted to demonstrate the efficiency of the INTrUMEr model in detecting network trafficwith high accuracy for different *** outperforms state-of-the-art approaches,obtaining better performance metrics:98.7%accuracy,97.5%precision,96.3%recall,and 97.8%*** results validate the robustness and effectiveness of INTrUMEr in securing diverse cloud environments against sophisticated cyber threats.

关键词： Cloud computing intrusion detection system transformers and explainable artificial intelligence(XAI)

Emerging potential of progranulin-dependent SorCS2 signaling in healthy and diseased nervous systems

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Neural regeneration research 2025年第9期20卷 2591-2593页

作者： Alena Salasova Anders Nykjær Danish research Institute of Translational Neuroscience DANDrITE-Nordic EMBL Partnership for Molecular Medicine and Centre of Excellence PROMEMODepartment of BiomedicineAarhus UniversityAarhusDenmark

The formation of the mammalian nervous system and its maturation into sensory,motor,cognitive,and behavioral circuits is a complex process that begins during early embryogenesis and lasts until young *** neurodevelopm... 详细信息

关键词： progr jointly CS2

Smart polymers for the controlled delivery of drugs–a concise overview

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Acta Pharmaceutica Sinica B 2014年第2期4卷 120-127页

作者： Honey Priya James rijo John Anju Alex Anoop k.r. Department of Pharmaceutics Amrita School of PharmacyAmrita Vishwa Vidyapeetham UniversityAIMS Healthcare CampusKochiKerala 682041India

Smart polymers have enormous potential in various *** particular,smart polymeric drug delivery systems have been explored as“intelligent”delivery systems able to release,at the appropriate time and site of action,entrapped drugs in response to specific physiological *** polymers exhibit a non-linear response to a small stimulus leading to a macroscopic alteration in their structure/*** responses vary widely from swelling/contraction to *** of new polymers and crosslink.r. with greater biocompatibility and better biodegradability would increase and enhance current *** most fascinating features of the smart polymers arise from their versatility and tunable *** most significant weakness of all these external stimuli-sensitive polymers is slow response *** versatility of polymer sources and their combinatorial synthesis make it possible to tune polymer sensitivity to a given stimulus within a narrow *** of smart polymer systems may lead to more accurate and programmable drug *** this review,we discuss various mechanisms by which polymer systems are assembled in situ to form implanted devices for sustained release of therapeutic macromolecules,and we highlight various applications in the field of advanced drug delivery.

关键词： Smart polymers Temperature responsive polymers pH responsive polymers Field sensitive polymers Glucose responsive polymers

Quanta-A platform for rapid control and monitoring of heterogeneous rbots

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Digital Communications and Networks 2020年第4期6卷 452-462页

作者： S.Sankhar reddy CH. Anita Agrawal Anupama k.r. E.E.E Department BITS PilaniK K Birla Goa CampusGoa403726India

rapid prototyping,real-time control and monitoring of various events in robots are crucial requirements for research in the fields of modular and swarm robotics.A large quantities of resources(time,man power,infrastructure,etc.)are often invested in programming,interfacing the sensors,debugging the response to algorithms during prototyping and operational phases of a robot development *** cost of developing an optimal infrastructure to efficiently address such control and monitoring requirements increases significantly in the presence of mobile *** numerous solutions have been developed for minimizing the resources spent on hardware prototyping and algorithm validation in both static and mobile scenarios,it can be observed that researchers have either chosen methodologies that conflict with the power and infrastructure constraints of the research field or generated constrained solutions whose applications are restricted to the field *** paper develops a solution for addressing the challenges in controlling heterogeneous mobile robots.A platform named Quanta-a cost effective,energy efficient and high-speed wireless infrastructure is prototyped as a part of the research in the field of modular *** is capable of controlling and monitoring various events in/using a robot with the help of a light-weight communication protocol independent of the robot hardware architecture(s).

关键词： modular robotics Swarm robotics Concurrent control and monitoring Event scheduling Centralized/decentralized communication