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Productivity of coalbed methane wells in southern of Qinshui Basin

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Mining Science and Technology 2010年第5期20卷 765-769,777页

作者： ZOU Mingjun WEI Chongtao PAN Haiyang SESAY k Santigie CAO Jia School of Resources and Geoscience China University of Mining & Technology Xuzhou 221116 China key Laboratory of CBM Resource and Reservoir-Generating Process Ministry of Education Xuzhou 221008 China

Based on regional CBM geological characteristics and drainage data of three typical Coalbed Methane(CBM) wells in the southern Qinshui Basin,history matching,productivity prediction and factor analysis of gas production control are conducted by using COMET3 reservoir modeling *** results show that in the next 20 years,the cumulative and average daily gas production of the QN01 well are expected to be 800×104 m3 and 1141.1 m3/d,for the QN02 well 878×104 m3 and 1202.7 m3/d and 97.5×104 m3 and 133.55 m3/d for the QN03 *** content and reservoir pressure are the key factors controlling gas production in the area;coal thickness,permeability and porosity are less important;the Langmuir volume,Langmuir pressure and adsorption time have relatively small *** the process of CBM recovery,the material source and driving force are the key features affecting gas productivity,while the permeation process is relatively important and the desorption process has some impact on gas recovery.

关键词： reservoir modeling history matching productivity prediction COMET3

Carbon dioxide-angiography for patients with peripheral arterial disease at risk of contrast-induced nephropathy

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World Journal of Cardiology 2020年第2期12卷 76-90页

作者： Amol Gupta Akinsansoye k Dosekun Vinod kumar Department of Cardiology HeartVascular and Leg CenterBakersfieldCA 93309United States Department of Nephrology University of TexasHoustonTX 77030United States

Patients with peripheral arterial disease(PAD)and critical limb ischemia are at risk for limb amputation and require urgent management to restore blood *** with PAD often have several comorbidities,including chronic kidney disease,diabetes mellitus,and *** and interventional angiography using iodinated contrast agents provides excellent image resolution but can be associated with contrast-induced nephropathy(CIN).The use of carbon dioxide(CO2)as a contrast agent reduces the volume of iodine contrast required for angiography and reduces the incidence of ***,CO2 angiography has been underutilized due to concerns regarding safety and image *** CO2 delivery systems with advanced digital subtraction angiography techniques and hybrid angiography have improved imaging accuracy and reduced the incidence of *** of the need for optimal imaging conditions,contraindications,and potential complications have improved the safety of CO2 *** review aims to highlight current technological advances in the delivery of CO2 in vascular angiography for patients with PAD and critical limb ischemia,which result in limb preservation while preventing kidney damage.

关键词： Endovascular procedures Angiography Digital subtraction Chronic kidney disease Peripheral artery disease Carbon dioxide

Intra-protein interactions of SARS-CoV-2 and SARS:a bioinformatic analysis for plausible explanation regarding stability,divergency,and severity

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Systems Microbiology and Biomanufacturing 2022年第4期2卷 653-664页

作者： Debanjan Mitra Aditya k.Pal Pradeep kr.Das Mohapatra Department of Microbiology Raiganj UniversityRaiganjWBIndia

The current nightmare for the whole world is *** occurrence of concentrated pneumonia cases in Wuhan city,Hubei province of China,was first reported on December 30,***-CoV first disclosed in 2002 but had not outspread *** 18 years,in 2020,it reemerged and outspread worldwide as SARS-CoV-2(COVID-19),as the most dangerous virus-creating disease in the *** it possible to create a favorable evolution within the short time(18 years)?If possible,then what are those properties or factors that are changed in SARS-CoV-2 to make it undefeated?What are the fundamental differences between SARS-CoV-2 and SARS?The study is one of the initiatives to find out all those ***,four types of protein sequences from SARS-CoV-2 and SARS were retrieved from the database to study their physicochemical and structural *** showed that charged residues are playing a pivotal role in SARS-CoV-2 evolution and contribute to the helix *** formation of the cyclic salt bridge and other intra-protein interactions specially network aromatic-aromatic interaction also play the crucial role in *** comparative study will help to understand the evolution from SARS to SARS-CoV-2 and helpful in protein engineering.

关键词： COVID-19 Evolution Cyclic salt bridge Intra-protein interactions Protein engineering

Mass drug administration for lymphatic filariasis elimination in a coastal state of India: a study on barriers to coverage and compliance

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Infectious Diseases of Poverty 2014年第1期3卷 294-301页

作者： Mohammad A Hussain Ashok k Sitha Subhashisa Swain Shridhar kadam Sanghamitra Pati School of Population Health The University of QueenslandHerstonBrisbaneQLD 4006Australia Government of Odisha OdishaIndia Public Health Foundation of India Indian Institute of Public HealthBhubaneswarOdishaIndia

Background:Lymphatic filariasis is targeted for elimination in India through mass drug administration(MDA)with diethylcarbamazine(DEC)combined with albendazole(ABZ).For the strategy to be effective,>65%of those living in endemic areas must be covered by and compliant to *** the MDA 2011 campaign in the endemic district of Odisha,we conducted a survey to assess:(i)the filariasis knowledge in the community,(ii)the coverage and compliance of MDA from the community perspective,and(iii)factors affecting compliance,as well as the operational issues involved in carrying out MDA activities from the drug distributor’s ***:A sample of 691 participants-both male and female,aged two years or above-were selected through multistage stratified sampling and interviewed using a semi-structured ***,drug distributors and the medical officers in charge of the MDA were also interviewed to understand some of the operational issues encountered during ***:Ninety-nine percent of the study participants received DEC and ABZ tablets during MDA,of which only just above a quarter actually consumed the *** cause of non-compliance was mostly due to fear of side effects,lack of awareness of the benefits of MDA,and non-attendance of health staff in the *** of adequate training of drug distributors and poor health communication activities before the MDA campaign commenced and the absence of follow-up by health workers following MDA were a few of the operational difficulties encountered during the MDA ***:Currently MDA is restricted to the distribution of drugs only and the key issues of implementation in compliance,health education,managing side effects,and logistics are not given enough *** is therefore essential to address the issues linked to low compliance to make the program more efficient and achieve the goal of filariasis elimination.

关键词： Lymphatic filariasis Mass drug administration Compliance Consumption Elimination

Long-term behavior of positive solutions of an exponentially self-regulating system of difference equations

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International Journal of Biomathematics 2017年第3期10卷 285-297页

作者： N. Psarros G. Papaschinopoulos k. B. Papadopoulos School of Engineering Democritus University of Thrace Xanthi 67100 Greece American University of the Middle East Kuwait

In this paper, we study the asymptotic behavior of the positive solutions of a system of the following difference equations：xn＋1=ayn＋bxne^-xn-yn , yn＋1=cxn＋dyne^-xn-yn ,where a, b, c, d are positive constants and... 详细信息

关键词： Difference equations exponentially self-regulating system boundedness persistence asymptotic behavior.

Chronic Liver Failure-Sequential Organ Failure Assessment is better than the Asia-Pacific Association for the Study of Liver criteria for defining acute-on-chronic liver failure and predicting outcome

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World Journal of Gastroenterology 2014年第40期20卷 14934-14941页

作者： Radha k Dhiman Swastik Agrawal Tarana Gupta Ajay Duseja Yogesh Chawla Department of Hepatology Postgraduate Institute of Medical Education and Research Chandigarh 160012 India

AIM: To compare the utility of the Chronic Liver Failure-Sequential Organ Failure Assessment (CLIF-SOFA) and Asia-Pacific Association for the Study of Liver (APASL) definitions of acute-on-chronic liver failure (ACLF)... 详细信息

关键词： Cirrhosis Acute decompensation Mortality Prognosis Acute on chronic liver failure

Preparation and Application of Polymyxin B Affinity Membrane Cartridge

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Chinese Chemical Letters 1997年第8期8卷 745-746页

作者： Guo, W Shang, ZH Yu, YN Zhou, LM Zhou, k CHINESE ACAD SCI DALIAN INST CHEM PHYSDALIAN 116012PEOPLES R CHINA SHANGHAI MED UNIV ZHONGSHAN HOSPSHANGHAI 200032PEOPLES R CHINA

Affinity membrane was used for the endotoxin adsorption. The matrix macropore membrane was prepared from filterpaper by chemically crosslinking, and polymyxin B was immobilized as affinity ligand. The prepared membrane cartridge can be used for the removal of endotoxin from aqueous solutions. With a cartridge of 40 sheets affinity membrane containing, the endotoxin level of the processed solution can be reduced to a minimum of 4 pg/mL.

关键词： REMOVAL

Network rewiring,adaptive resistance and combating strategies in breast cancer

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Cancer Drug Resistance 2019年第4期2卷 1106-1126页

作者： Constance Gaya Cremers Lan k.Nguyen Department of Biochemistry and Molecular Biology School of Biomedical SciencesMonash UniversityClaytonVictoria 3800Australia Biomedicine Discovery Institute Monash UniversityClaytonVictoria 3800Australia

Resistance to targeted anti-cancer drugs is a complex phenomenon and a major challenge in cancer *** is becoming increasingly evident that a form of acquired drug resistance known as“adaptive resistance”is a common cause of treatment failure and patient relapse in many *** classical resistance mechanisms that are acquired via genomic alterations,adaptive resistance is instead driven by non-genomic changes involving rapid and dynamic rewiring of signalling and/or transcriptional networks following therapy,enabled by complex pathway crosstalk and feedback *** network rewiring allows tumour cells to adapt to the drug treatment,circumvent the initial drug challenge and continue to survive in the presence of the *** its great clinical importance,adaptive resistance remains largely under-studied and poorly *** review is focused on recent findings which provide new insights into the mechanisms underlying adaptive resistance in breast cancer,highlighting how breast tumour cells rewire intracellular signalling pathways to overcome the stress of initial targeted *** particular,we investigate adaptive resistance to targeted inhibition of two major oncogenic signalling axes frequently dysregulated in breast cancer,the PI3k-AkT-mTOR and RAS-MAPk signalling pathways;and discuss potential combination treatment strategies that overcome such *** addition,we highlight application of quantitative and computational modelling as a novel integrative and powerful approach to gain network-level understanding of network rewiring,and rationally identify and prioritise effective drug combinations.

关键词： Network rewiring adaptive resistance PI3k signalling MAPk signalling breast cancer mathematical modelling systems analysis

Harnessing coherence of area decomposition and semantic shared spaces for task allocation in a robotic fleet

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Information Processing in Agriculture 2014年第1期1卷 23-33页

作者： Domagoj Drenjanac Slobodanka Dana kathrin Tomic Lukas klausner Eva kühn The Telecommunications Research Center Vienna(FTW) Donau-City-Strasse 11220 ViennaAustria Institute of Computer Languages Vienna University of TechnologyArgentinierstrasse 81040 ViennaAustria

Task allocation is a fundamental problem in multi-robot systems where heterogeneous robots cooperate to perform a complex mission.A general requirement in a task allocation algorithm is to find an optimal set of robots to execute a certain *** paper presents the work that harnesses an area decomposition algorithm,and a space-based middleware to facilitate task allocation process in unstructured and dynamic *** reduce spatial interference between robots,area decomposition algorithm divides a working area into cells which are then dynamically assigned to *** addition,coordination and collaboration among distributed robots are realized through a space-based *** this purpose,the space-based middleware is extended with a semantic model of robot capabilities to improve task selection in terms of flexibility,scalability,and reduced communication overhead during task *** this way a framework which exploits the synergy of area decomposition and semantically enriched space-based approach is *** conducted performance tests in a specific precision agriculture use case focusing on the utilization of a robotic fleet for weed control introduced in the European Project RHEA–Robot Fleets for Highly Effective Agriculture and Forestry Management.

关键词： Task allocation Area decomposition Space-based computing Semantics Robotic fleet