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A Study into Digital Dermatitis Transmission and Bacterial Associated Pathological Changes Involved in the Disease

Open Journal of Veterinary Medicine 2013年第2期3卷 192-198页

作者： N.Capion M.Boye C.Ekstrom k.dupont T.k.Jensen Department of Large Animal Sciences Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark National Veterinary Institute Technical University of DenmarkCopenhagenDenmark Department of Biostatistics University of Southern DenmarkOdenseDenmark

Digital dermatitis is a highly prevalent painful lesion affecting the feet in dairy cattle. Even though the pathogenesis has been subject of investigation since 1974, there is still a lack of knowledge about the spread of the disease among cows within a herd as well as between herds. The purpose of this study was to monitor transmission of digital dermatitis under experimental conditions between naive heifers and affected animals, to monitor the changes in clinical appearance, microbial colonisation of the skin as lesions progressed and to apply a q-PCR for the detection of Treponema spp. in faecal samples. Eight heifers with clinical normal digital skin were housed with 5 heifers with severe digital dermatitis lesion for 8 weeks on a solid concrete floor with an accumulating layer of slurry. Digital skin was examined daily and lesions were clinically scored. Skin biopsies were taken from the healthy heifers at introduction and weekly from all lesions for histopathological evaluation and fluorescence in situ hybridization. None of the healthy heifers developed digital dermatitis and in 4 out of 5 infected heifers the lesions healed during the study. All samples from healthy skin were negative for Treponema spp. and one sample were positive for Dichelobacter nodosus. Colonization of healthy skin could not be identified in this study. There was no significant relation between clinical scoring of the lesions and histopathological score and the presence of Treponema spp. There were however a significant relation between the prevalence of Treponema spp. in the skin and severity of changes in epidermis and dermis. By qPCR all the healthy heifers were found to excrete Treponema spp. in their faeces.

关键词： Digital Dermatitis Treponema spp. Histopathology Infection Dynamics

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Residence time distribution of wood chips in a semi-industrial multiple hearth furnace using RFID tracers Author links open overlay panel

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Particuology 2024年第8期91卷 268-279页

作者： Elie Lacombe Muriel Marchand Capucine dupont Denis Maréchal Thierry Melkior Univ Grenoble Alpes CEALITENDTCHLaboratoire Réacteurs et ProcédésF-38000GrenobleFrance IHE Delft Department of Water Supply Sanitation and Environmental EngineeringDelftthe Netherlands John Cockerill SeraingBelgium

In continuous biomass torrefaction plants,the products'yields,composition and homogeneity highly depend on the residence time of particles.A characterization of particle residence time distribution(RTD)was therefore carried out in an industrial-scale multiple hearth furnace on poplar wood chips using radio frequency identification *** effects of operating conditions,namely,mass flow rate of biomass,shaft speed of the rabbling system and interdental length on the RTD were *** increase of shaft speed and mass flow rate reduces particles’mean residence *** the length between two successive teeth also increases the bed *** biomass accumulation(also called“bulldozing”)was observed during several *** phenomenon is favored by a high mass flow rate of resources,a small interdental length between the teeth and a low shaft *** measurements were compared to the axial dispersion *** all tests,the Peclet number is ranging between 20 and 62,indicating that the multiple hearth furnace cannot be modelled as an ideal plug flow reactor.

关键词： Biomass Multiple hearth furnace Residence time distribution RFID

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Machine learning approach to assess the association between anthropometric,metabolic,and nutritional status and semen parameters

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Asian Journal of Andrology 2024年第4期26卷 349-355页

作者： Guillaume Bachelot Antonin Lamaziere Sebastien Czernichow Celine Faure Chrystelle Racine Rachel Levy Charlotte dupont Nutrition and Fertility(ALIFERT)Group Author Information Sorbonne University School of Medicine Saint-Antoine Research CenterINSERM UMR 93827 rue ChalignyParis 75012France Reproductive Biology Department-CECOS Tenon HospitalAP-HP.Sorbonne UniversityParis 75020France Clinical Metabolomics Department Saint-Antoine HospitalAP-HP27 rue ChalignyParis 75012France Nutrition Department Obesity Specialist CentreGeorges Pompidou European HospitalAP-HPParis 75015France 不详

Many lifestyle factors,such as nutritional imbalance leading to obesity,metabolic disorders,and nutritional deficiency,have been identified as potential risk factors for male *** aim of this study was to evaluate the relationship between semen parameters and anthropometric,metabolic and nutritional *** was first assessed individually,then after the application of a previously constructed and validated machine learning score that allows their ***,metabolic,antioxidant,micronutrient,and sperm parameters from 75 men suffering from idiopathic infertility from four infertility centers in France(Jean-Verdier ART Center Hospital,Bondy;North Hospital ART Center,Saint-Étienne;Navarre Polyclinic ART Center,Pau;and Cochin Hospital ART Center,Paris)between September 2009 and December 2013 were *** assessing standard correlation analysis,a previously built machine learning model,providing a score ranging from 0(the poorest)to 1(the most favorable),was calculated for each man in the study *** machine learning model,which separates infertile/fertile men with unexplained infertility on the basis of their bioclinical signature,provides a more holistic evaluation of the influence of the considered markers(anthropometric,metabolic,and oxidative status).We observed a significant correlation of some anthropometric,metabolic,and nutritional disorders with some sperm ***,an unfavorable machine learning score was associated with a high level of sperm DNA *** anthropometric,metabolic,and oxidative patterns,which may reflect an appropriate lifestyle,appear to positively impact overall health,in particular reproductive *** study,consistent with previous publications,suggests that beyond semen quality parameters,in an essential assessment of male fertility,other key factors should be taken into *** this regard,the application of emerging artificial intelligence t

关键词： lifestyle machine learning metabolism nutrition sperm DNA fragmentation

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Apoptosis in skeletal muscle and its relevance to atrophy

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World Journal of Gastroenterology 2006年第46期12卷 7463-7466页

作者： Esther E dupont-Versteegden University of Arkansas for Medical Sciences Departments of Geriatrics and Physiology and Biophysics 4301 West Markham #807 Little Rock AR 72205 and University of Kentucky Department of Rehabilitation Sciences Division of Physical Therapy 900 S Limestone Lexington KY 40536-0200 United States

Apoptosis is necessary for maintaining the integrity of proliferative tissues, such as epithelial cells of the gastrointestinal system. The role of apoptosis in post mitotic tissues, such as skeletal muscle, is less well defined. Apoptosis during muscle atrophy occurs in both myonuclei and other muscle cell types. Apoptosis of myonuclei likely contributes to the loss of muscle mass, but the mechanisms underlying this process are largely unknown. Caspase-dependent as well as -independent pathways have been implicated and the mode by which atrophy is induced likely determines the apoptotic mechanisms that are utilized. It remains to be determined whether a decrease in apoptosis will alleviate atrophy and distinct research strategies may be required for different causes of skeletal muscle loss.

关键词： Skeletal muscle Apoptosis Disuse atrophy Aging

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三轴形变核^(131)Ba中的奇异集体激发模式

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物理学报 2024年第11期73卷 89-100页

作者：韦锐周厚兵王思成丁兵强赟华贾晨旭陈红星郭松 C.M.Petrache D.Mengoni A.Astier E.dupont 吕冰锋 D.Bazzacco A.Boso A.Goasduff F.Recchia D.Testov F.Galtarossa G.Jaworski D.R.Napoli S.Riccetto M.Siciliano J.J.Valiente-Dobon C.Andreoiu F.H.Garcia k.Ortner k.Whitmore A.Ataç-Nyberg T.Bäck B.Cederwall E.A.Lawrie I.kuti D.Sohler T.Marchlewski J.Srebrny A.Tucholski 广西师范大学物理科学与技术学院桂林541004 广西核物理与核技术重点实验室桂林541004 中国科学院近代物理研究所兰州730000 中国科学院大学北京100049 巴黎萨克雷大学 CNRS/IN2P3IJCLab奥赛91405 帕多瓦大学物理和天文学系帕多瓦I-35131 意大利国家核物理研究所帕多瓦分部帕多瓦I-35131 意大利国家核物理研究所莱尼亚罗国家实验室莱尼亚罗(帕多瓦)I-35020 费拉拉大学理学与自然科学院费拉拉西蒙菲莎大学化学系本拿比BC V5A 1S6 皇家理工学院物理系斯德哥摩尔S-10691 国家研究基金会iThemba加速器科学实验室西萨默塞特7123 西开普大学物理与天文系贝尔维尔ZA-7535 HUN-REN原子核研究所德布勒森4001 华沙巴斯德拉大学重离子实验室华沙02-093

利用意大利Legnaro实验室串列静电加速器提供的65 MeV^(13)C束流与122Sn靶的熔合蒸发反应布居了^(131)Ba的高自旋态,并搭建了新的能级纲图.新的能级纲图由15条转动带组成,包括三对手征双重带,其中两对正宇称手征带为赝自旋-手征四重带.... 详细信息

利用意大利Legnaro实验室串列静电加速器提供的65 MeV^(13)C束流与122Sn靶的熔合蒸发反应布居了^(131)Ba的高自旋态,并搭建了新的能级纲图.新的能级纲图由15条转动带组成,包括三对手征双重带,其中两对正宇称手征带为赝自旋-手征四重带.正负宇称手征带通过一系列增强的E1跃迁连接,表明它们之间存在八极关联.在低自旋区域搭建了一条新的转动带,通过一系列γ跃迁向νh1_(1/2)晕带退激.这种能级结构与摇摆带相似,但基于现有的实验证据还难以将它确认为摇摆带,不能排除其他集体激发机制,如γ振动的影响.

关键词：高自旋态手征带赝自旋八极关联摇摆运动

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Parentage analysis in Gabonese colonies of soil-feeding termites belonging to the Cubitermes sp. affinis subarquatus complex of species （Termitidae＂ Termitinae）

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Insect Science 2010年第2期17卷 84-90页

作者： Virginie Roy Lise dupont Myriam Harry Unite Mixte de Recherche 7618 Bioemco Universite Paris 12-Val de Mame 61 avenue du Gen6ral de Gaulle 94010 Creteil cedex Laboratoire Evolution Genomes et Speciation UPRg034 Centre National de la Recherche Scientifique 91198 Gif sur YvetteFrance

Cubitermes spp. are widely distributed soil-feeding termite species in sub- Saharan Africa which play a fundamental role in soil structure and fertility. A complex of at least four cryptic species （i.e., Cubitermes sp. affunis subarquatus complex of species） has been recently described using molecular markers. In order to investigate the breeding system of these species, five microsatellite markers were used to carry out parentage and re- latedness analyses in 15 Gabonese colonies. Monogamy was confirmed as the predominant reproductive organization in Cubitermes spp. （76% of the colonies）. Within 30% of these monogamous colonies, a high relatedness between reproductives was shown, suggesting that mating between related individuals occurs. However, Cubitermes colonies can deviate from monogamy. Indeed, parental contributions by at least two related reproductives of the same sex were revealed in four colonies and polyandry was demonstrated in two of them. Infiltration of reproductives in the colony is the most plausible explanation for such cases of polygamy in Cubitermes spp.

关键词： breeding system Cubitermes spp. microsatellite markers monogamy soil- feeding termites

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Numerical and experimental comparison of the vaned diffuser interaction inside the impeller velocity field of a centrifugal pump

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Science China(Technological Sciences) 2011年第2期54卷 286-294页

作者： ATIF Abdelmadjid BENMANSOUR Saad BOIS Gerard dupont Patrick Laboratory of Advanced Mechanics FGMGP/USTHBBP32 El Alia16111AlgerAlgeria Laboratory of Mechanics of Lille ENSAM-Lille8 Bd Louis XIV59046LilleFrance Laboratory of Mechanics of Lille EC-LilleBP48 Villeneuve d’Ascq59651LilleFrance

The paper refers to the analysis of interactions between the impeller and the vaned diffuser based on the air model of a radial flow *** study deals with a numerical simulation of the flow for a full 360°entire impeller and *** task is carried out closely under the design operating conditions and for one particular position of the impeller blade with respect to the diffuser *** all the results,the focus is mainly on the flow pattern at the exit part inside the impeller facing the diffuser *** results are compared to the available PIV measurements.

关键词： centrifugal pump impeller vaned diffuser rotor-stator interaction

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Impacts of ocean acidification under multiple stressors on typical organisms and ecological processes

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Marine Life Science & Technology 2020年第3期2卷 279-291页

作者： kunshan Gao Guang Gao Youji Wang Sam dupont State key Laboratory of Marine Environmental Science and College of Ocean and Earth Sciences Xiamen UniversityXiamen 361005China International Research Center for Marine Biosciences at Shanghai Ocean University Ministry of Science and TechnologyShanghai 201306China Department of Biological and Environmental Sciences(BioEnv) University of GothenburgThe Sven Loven Centre for Marine Infrastructure-Kristineberg45178 FiskebackskilSweden

The oceans are taking up over one million tons of fossil CO_(2) per hour,resulting in increased/ρCO_(2) and declining pH,leading to ocean acidification(OA).At the same time,accumulation of CO_(2) and other greenhouse gases is causing ocean warming,which enhances stratification with thinned upper mixed layers,exposing planktonic organisms to increasing levels of daytime integrated UV *** warming also reduces dissolved oxygen in seawater,resulting in ocean *** these ocean global changes are impacting marine ecosystems and effects are well documented for each individual driver(pH,oxygen,temperature,UV).However,combined effects are still poorly understood,strongly limiting our ability to project impacts at regional or local *** regions are often exposed(and often adapted)to contrastingly different physical and chemical environmental conditions and organisms,and ecosystems from different parts of the world will be exposed to unique combinations of stressors in the *** the modulating role of adaptation,species niche and stressors’interaction is *** review,being a non-exhaustively explored *** to provide an overview on understandings of ecophysiological effects of OA and its combination with covarying drivers,mainly warming,deoxygenation and solar UV *** propose a testable hypothetical model as well as future research perspectives.

关键词： Algae Deoxygenation Ocean acidification Ocean warming Plankton UV radiation

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Exploring the potential impact of nutritionally actionable genetic polymorphisms on idiopathic male infertility:a review of current evidence

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Asian Journal of Andrology 2021年第5期23卷 441-449页

作者： Sinda Mahbouli Charlotte dupont Yaelle Elfassy Eric Lameignere Rachel Levy FabLife 104 Avenue Albert lerRueil-Malmaison 92500France Sorbonne University Saint Antoine Research CentreINSERM Genetic and Acquired Lipodystrophies TeamReproductive Biology and CECOSAP-HPTenon HospitalParis F-75020France Reproductive Biology and CECOS AP-HPTenon HospitalParis F-75020France

Infertility affects about 15%of the world's *** 40%-50%of infertile couples,a male factor underlies the problem,but in about 50%of these cases,the etiology of male infertility remains *** clinical data show that lifestyle interventions may contribute to male reproductive *** of unhealthy habits is suggested for preserving male fertility;there is growing evidence that most preexisting comorbidities,such as obesity and metabolic syndrome,are highly likely to have an impact on male *** analysis of genetic polymorphisms implicated in metabolic activity represents one of the most exciting areas in the study of genetic causes of male *** these polymorphisms are not directly connected with male infertility,they may have a role in specific conditions associated with it,that is,metabolic disorders and oxidative stress pathway genes that are potentially associated with an increased risk of male infertility due to DNA and cell membrane *** studies have examined the impact of individual genetic differences and gene-diet interactions on male infertility,but their results have not been *** review the current research to identify genetic variants that could be tested to improve the chances of conceiving spontaneously through personalized diet and/or oral vitamin and mineral supplementation,by examining the science of genetic modifiers of dietary factors that affect nutritional status and male fertility.

关键词： energy metabolism genetic polymorphisms idiopathic male infertility lifestyle factors nutrition oxidative stress semen quality

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Effect of Virtual Team Collectivism on Shared Leadership:Examining the Moderating Roles of Transformational Leadership and Team Trust

Effect of Virtual Team Collectivism on Shared Leadership:Exa...

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作者： Tanguy dupont 上海交通大学

学位级别：硕士

These last decades have witnessed simultaneously evolving and influencing each other the internet with faster ways to communicate around the globe,as well as large multinational companies and *** is unclear whether the internet has allowed and forced organizations to grow global,or if the need to grow global has influenced research in this *** can easily admit that they both influenced each *** evolution has brought new ways of working,researching and bringing creativity and *** central pillar on which organizations now rely is not a single talented leader,as it has become impossible to hold this position in a traditional way and make the best possible decision in such complex ***,global organizations rely mostly on working teams,which have become the most effective way to optimize output for organizations,as teams can share and challenge themselves to make a better contribution,using diversified talents and several nationalities that better fit the *** an international level and using the multiple means of communication that we have today,those teams are often *** with the traditional face to face teams,they are globally *** way virtual teams function and react to different situations is a frequently raised topic in all organizations *** become more common and research is still at its very *** generation is facing the challenge of making individuals from different culture work together,not only having to overcome the cultural gap,but also the virtual gap as they work on different sites,different countries and connect together through the *** research investigates how team collectivism affects shared leadership in a virtual *** topic enlightens the factors that influence shared leadership;based on previous studies,it is known that shared leadership in teams is strongly correlated to team performance,which is the main focus of organizations.I also l

关键词：虚拟团队集体主义共享领导变革型领导团队信任

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