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Applied Biofloc Technology for Target Species in the Mekong Delta in Vietnam： A Review

The 8th International congress on SLE

作者： Amy H.kao Jeannine S.Navratil Margie J.Ruffing chau-ching Liu Douglas Hawkins Andras Varadi kathleen M. Mckinnon Joseph M.Abearn Susan Manzi University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine School of Statistics University of MinnesotaMinneapolisMinnesotaUSA University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine University of Pittsburgh School of Medicine University of Pittsburgh Graduate School of Public HealthPittsburghPennsylvaniaUSA

＜正＞Purpose:Disease activity monitoring in patients with systemic lupus erythematosus（SLE）is challenging,and traditionally has utilized serum c3 and c4 as an indirect measure of complement ***,these proteins have ...

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Journal of Environmental Science and Engineering(B) 2017年第4期6卷 165-175页

作者： Nguyen Van Hoa Ta Van Phuong Tran Ngoc Hai chau Tai Tao Le Quoc Viet Nguyen Thi Hong Van Huynh Thanh Toi Tran Huu Le Vo Nam Son Pham Quoc Anh Duy college of Aquaculture and Fisheries (cAF) Cantho University Cantho 270000-910000 Vietnam college of Applied Biology Tay Do University Cantho 270000-910000 Vietnam

BFT （Biofloc Technology） has been currently applied in cantho University to a number of targeted species from fresh-to marine and saline water species in the Mekong Delta, e.g. striped catfish （Pangasianodon hypophthalmus）, white leg shrimp （Litopenaeus vannamei）, tiger shrimp （Penaeus monodon） and Artemia Vinhchau strain （Artemia franciscana） for both in the lab-scales or production scales. The best growth and survival rate of striped catfish was obtained in 6%o. For white leg shrimp, the results indicated：（1） c （carbon） source e.g. rice-flour or molasses supplementary based on the feed provided to promote survival, growth and shrimp biomass harvested; （2） it was fed less than 20% as usual but showed similar to those in the control; （3） combination of rice-flour and molasses at a ratio of 70：30 by weight of c and N （Nitrogen） in a ration of 15：1 enhanced shrimp survival and growth; （4） in intensive culture, shrimp could be against the infection of disease and end up with higher survival, growth in earthen ponds. For tiger shrimp, a set up for larvae till post larvae at different ratios of c and N and c：N of 30 PLI5 displayed with better survival rate （49.73 ± 7.07%） and production （74,596 ± 10.608 PL/m3）. Artemiafranciscana was set up at c：N = 10：1 and salinities from 35, 60, 80 and 100 ppt. After two weeks, there were no significant difference among treatment and the control （without biofloc） in term of survival and growth. Moreover, total embryos per female was not significant different with the control and even the number of embryos as cysts tended to be higher. BFT displayed its advantages when applied on culture system of different targeted species and there is no doubt that it could help to sustain aquaculture and save environment in the Mekong Delta in near future.

关键词： Biofloc techology striped catfish white leg shrimp tiger shrimp Artemia Vinhchau strain.

(R)-乙基-2-吡啶亚砜与(4R,5R)-TADDOL包结晶体[c_7H_9NOS·c_(31)H_(30)O_4]的晶体结构分析

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高等学校化学学报 1999年第7期20卷 1081-1084页

作者：朱槿周忠远付芳敏邓金根宓爱巧蒋耀忠邱太源中国科学院成都有机化学研究所不对称合成联合开放实验室中兴大学化学系

（Ｒ）－乙基－２－吡啶亚砜与（４Ｒ，５Ｒ）－二（羟基－二苯基－甲基）－２，２－二甲基－１，３－二氧戊环（ＴＡＤ－ＤＯＬ）可以形成物质的量比为１∶１的手性包结晶体，Ｘ射线衍射分析确定该晶体属单钭晶系，Ｐ２１空间群，ａ＝... 详细信息

（Ｒ）－乙基－２－吡啶亚砜与（４Ｒ，５Ｒ）－二（羟基－二苯基－甲基）－２，２－二甲基－１，３－二氧戊环（ＴＡＤ－ＤＯＬ）可以形成物质的量比为１∶１的手性包结晶体，Ｘ射线衍射分析确定该晶体属单钭晶系，Ｐ２１空间群，ａ＝０．９７０１（２）ｎｍ，ｂ＝０．９９５３（２）ｎｍ，ｃ＝１．７３９２（２）ｎｍ；β＝９２．０７９°（１４），Ｖ＝１．６７８１（５）ｎｍ３，Ｚ＝２，Ｄｃ＝１．２３０ｇ／ｃｍ３，分子式Ｃ３８Ｈ３９ＮＯ５Ｓ，Ｍｒ＝６２１．７６，最终偏离因子Ｒ＝０．０３５１，ＲＷ２＝０．０７７２，Ｆｌａｃｋ值为０．１（２）．结构分析表明，主客体存在分子间氢键．光学纯的ＴＡＤＤＯＬ与消旋的乙基吡啶亚砜（１）作用时，ＴＡＤＤＯＬ对１具有很好的手性识别能力，选择性地与１的一个对映体形成氢键，长成晶体．

关键词：手性亚砜 TADDOL 包结晶体乙基吡啶亚砜拆分

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5—碘—3—氧杂—八氟戊磺酸—2’,2’,3’,3’—四氟丙酯与二甲亚砜的反应及结晶产物的晶体结构测定

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化学学报 1984年第2期42卷 120-124页

作者：李宗珍倪朝周马益林中国科学院上海有机化学研究所

标题反应产生三个已知化合物2,3,4和两个新的化合物cH3ScH2cF2cF2H（5）和I（cF2）2O（cF2）2SO3-+S（cH3）3（6）。6的结构经X射线衍射测定得到验证。 6的晶体属单斜晶系,空间群为P21/c;晶胞参数a=9.399A,b=15.651A,c=10.934A,β=94.80°;V=1602.8A3;Z=4;Dm=2.072gcm-3,Dc=2.073gcm-3。结构由重原子法解出,经各向同性和各向异性块对角矩阵最小二乘修正,对1999个可观察衍射点,最终R值为0.054。三甲基锍中的三个S-c键形成三棱锥体,其键长分别为1.814,1.800,1.818A,三个c-S-c键角为101.06°,101.52°,102.53°。三甲基锍中的S原子与磺酸根中三个O原子的距离分别为3.79,3.64,3.43A,大大超过S-O共价键的键长范围。整个晶体是由[（cH3）3S]+和[I（cF2）2O（cF2）2SO3]-组成的离子晶体。

关键词：晶体结构测定二甲四氟结晶学晶体学地质学产物磺酸硫化合物反应

L-胱氨酸与铅、镉、银、锰、钙、锶、钡等金属离子络合物稳定常数的测定

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暨南理医学报 1982年第2期 90-106页

作者：冯德雄周端赐黄洁心林雪辉暨南大学化学系

近年来,生物体中的化学现象的研究已涉及到许多领域,随着学科的互相渗透,尤其是在化学,生物和医学等学科的结合研究方面,已愈加密切和重要.特别是对于人体中的氨基酸与金属离子络合物的性质及其常数测定的研究方面,业已引起人们的广泛重... 详细信息

近年来,生物体中的化学现象的研究已涉及到许多领域,随着学科的互相渗透,尤其是在化学,生物和医学等学科的结合研究方面,已愈加密切和重要.特别是对于人体中的氨基酸与金属离子络合物的性质及其常数测定的研究方面,业已引起人们的广泛重视.胱氨酸具有促进机体细胞的氧化与还原机能,增加白血球及抑制细菌生长等作用,在人

关键词：金属离子平均配位数曲线图络合物稳定常数配位体

关节液中抗环瓜氨酸肽抗体在类风湿关节炎诊断和评估中的意义

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诊断学理论与实践 2006年第4期5卷 301-303页

作者：刘黎 Tran Thi To chau 陈晓翔吕良敬陆瑜陈顺乐鲍春德上海交通大学医学院附属仁济医院风湿科上海200001

目的:分析关节液中抗环瓜氨酸肽(ccP)抗体对类风湿关节炎(RA)的诊断和评估意义。方法:用ELISA法检测37例RA患者血清和关节液中的抗ccP抗体和13例对照组关节炎患者关节液中的抗ccP抗体,并测定类风湿因子(RF),记录RA患者的一些临床参数。... 详细信息

目的:分析关节液中抗环瓜氨酸肽(ccP)抗体对类风湿关节炎(RA)的诊断和评估意义。方法:用ELISA法检测37例RA患者血清和关节液中的抗ccP抗体和13例对照组关节炎患者关节液中的抗ccP抗体,并测定类风湿因子(RF),记录RA患者的一些临床参数。对检测结果及临床参数进行统计分析。结果:关节液中抗ccP抗体对RA诊断的敏感度为72.9%,特异度为92.3%。RA组和对照关节炎组患者的关节液中抗ccP抗体的差异有显著性。RA组血清与关节液中抗ccP抗体的浓度高度相关(PccP抗体与关节液中RF浓度有较高相关性(PccP抗体与病程相关,病程越长,抗ccP抗体滴度越高;而与肿胀关节数、压痛关节数、疾病活动评分(DAS28)、血清RF、红细胞沉降率(ESR)、c反应蛋白(cRP)和Steinbrocker放射线分级不相关。结论:关节液中抗ccP抗体对RA的诊断有高度特异性和较好敏感性,对其他关节炎有显著性差异,独立于一些临床参数,同时又与血清中抗ccP抗体及关节液中的RF相关。

关键词：抗环瓜氨酸肽抗体关节液类风湿关节炎

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Impact of adalimumab on disease burden in moderate-to-severe ulcerative colitis patients: The one-year, real-world UcanADA study

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World Journal of Gastroenterology 2022年第34期28卷 5058-5075页

作者： Talat Bessissow Geoffrey c Nguyen Osman Tarabain Laurent Peyrin-Biroulet Nathalie Foucault kevin McHugh Joannie Ruel Department of Medicine McGill University Health CenterMontreal H3G 1A4QuebecCanada Mount Sinai Hospital Inflammatory Bowel Disease centre Toronto M5T 3L9OntarioCanada Dr.O.Tarabain clinic Windsor N8W 1E6OntarioCanada Department of Gastroenterology University of LorraineCHRUNancyNancy F-54000France AbbVie corporation Saint-Laurent H4S 1Z1QuebecCanada Department of Medicine Sherbrooke University Hospital CenterSherbrooke J1H 5N4QuebecCanada

BAckGROUND A gap remains in documenting the impact of anti-tumor necrosis factor therapy on disease burden in ulcerative colitis(Uc)patients treated in a real-world *** use of patient-reported outcomes(PROs)has been discussed as a primary endpoint in the context of the FDA PRO Guidance,for labelling ***,the efficacy and safety of adalimumab have been demonstrated in pivotal trials;however,data are needed to understand how clinical results translate into improvements in key aspects of the daily lives of Uc patients,such as symptoms,health-related quality of life(HRQoL),and *** To assess real-world effectiveness of adalimumab on PRO measures in patients with moderate-to-severe *** UcanADA was a single arm,prospective,1-year multicenter canadian post-marketing observational study in which multiple PRO questionnaires were completed—with psychologic distress/depression symptoms as the primary endpoint—by patients with moderate-to-severe *** were performed during patients’routine care visit schedule,which was at the initiation of adalimumab(baseline),after induction(approximately 8 wk),and 52 wk after *** optional assessments between weeks 8 and 52 were collected at least once but no more than two times during this *** safety events and per-protocol adverse events were *** From 23 canadian centres,100 patients were enrolled and 48 completed the *** with the Patient Health Questionnaire–9 items at week 52,61.5%(40/65)[95%confidence interval(cI):49.7%-73.4%]of the patients improved in psychologic distress/depression symptoms,which was slightly higher in completers[65.9%(29/44);95%cI:51.9%-79.9%].At week 52,clinical response and clinical remission were achieved respectively by 65.7%(44/73)and 47.8%(32/73)of the *** odds of improving depressive symptoms for those achieving a clinical remission at week 52 was 7.94 higher compared with those not achieving a clinic

关键词： Disease burden Patient-reported outcome Depressive symptoms Ulcerative colitis Adalimumab Real-world data

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静脉应用硫酸镁治疗急性哮喘的meta分析

世界核心医学期刊文摘（儿科学分册） 2005年第5期1卷 21-21页

作者： cheuk D. k. L. chau T. c. H. Lee S. L. 高蕊 Dept. of Pediat. and Adol. Medicine Queen Mary Hospital University of Hong Kong 121 Pokfulam Road Hong Kong Hong KongDr.

Aim: To evaluate the effectiveness of intravenous magnesium sulphate in the tr eatment of acute asthmatic attacks in children by meta-analysis. Methods: A sys tematic and comprehensive search of the literature was performed to identify con trolled clinical trials of magnesiumsulphate in paediatric acute asthma which ev aluated outcomes of hospitalisation or short term pulmonary function tests or sy mptom scores. Unpublished data were searched by personal contacts with authors a nd specialists. Two reviewers independently assessed trial qualities and synthes ised data. Heterogeneity among studies was evaluated by the cochrane Q test. Out come data were pooled by random or fixed effect models depending on presence or absence of heterogeneity. Results: Five randomised placebo controlled trials inv olving a total of 182 patients were identified. They compared intravenous magnes ium sulphate to placebo in treating paediatric patients with moderate to severe asthmatic attacks in the emergency department, with co-therapies of inhaled β2 agonists and systemic steroids. The studies were of high quality with results j udged to be valid. Four studies showed that magnesium sulphate was effective, wh ile one study found it ineffective. There was no significant heterogeneity in th e primary outcome of hospitalisation. In the fixed effect model, magnesium sulph ate is effective in preventing hospitalisation (OR 0.290, 95%cI 0.143 to 0.5 89). The number needed to treat is 4 (95%cI 3 to 8). Secondary outcomes of shor t term pulmonary function tests and clinical symptom scores also showed signific ant improvement. conclusion: Intravenous magnesium sulphate probably provides ad ditional benefit in moderate to severe acute asthma in children treated with bro nchodilators and steroids.

关键词：硫酸镁治疗 meta分析急性哮喘肺功能检测肺功能检查重度哮喘自身对比随机对照试验临床症状评分安慰剂

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铅-谷氨酸络合物稳定常数的测定—pH滴定法

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暨南理医学报 1982年第1期 40-47页

作者：周端赐陈珍良冯德雄廖俊仪李素梅暨南大学化学系

测定络合物稳定常数,在理论和实践上都有重大意义。近廿年来,随着学科的互相渗透,特别在化学,生物,医学方面的深入研究,测定络合物稳定常数的工作显得更加重要,并已得到广泛重视。测定络合物稳定常数的方法很多,常用的有电位法,极谱法,... 详细信息

测定络合物稳定常数,在理论和实践上都有重大意义。近廿年来,随着学科的互相渗透,特别在化学,生物,医学方面的深入研究,测定络合物稳定常数的工作显得更加重要,并已得到广泛重视。测定络合物稳定常数的方法很多,常用的有电位法,极谱法,电流分析法,溶解度法等,其中PH滴定法、萃取法、极谱法有较多的研究和发展。在用离子选择性电极测定味精（谷氨酸的一钠盐）中微量元素时,我们发现在某个pH范围内,从仪器所读到的数值与实际含量有所不同,这是谷氨酸与pb2+络合的结果,鉴于谷氨酸在食品、生物化学、医药的广泛应用,而它与某些重金属元素的络合物稳定常数报导得很不完全,(如它与pb2+的络合物稳定常数未见报导)因此,进行对人体有害的重金属元素(如pb2+)与谷氨酸的络合物稳定常数的测定具有更大的现实意义。

关键词：络合物稳定常数谷氨酸 α-氨基戊二酸神经递体 NaOH 配位体滴定曲线滴定法化学法 pH