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Tailored nutritional interventions: A precision approach to managing gestational diabetes mellitus

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World Journal of Diabetes 2024年第5期15卷 1045-1047页

作者： Babita Pande Henu kumar Verma LVkS bhaskar Department of Physiology All India Institute of Medical ScienceChhattisgarhRaipur 492001India Lung Health and Immunity Helmholtz Zentrum MunichBayrenMunich 85764Germany Department of Zoology Guru Ghasidas VishwavidyalayaChhattisgarhBilaspur 495001India

Gestational diabetes mellitus(GDM)is a risk to maternal-fetal health due to uncertain diagnostic criteria and treatment ***'s study demonstrated the efficacy of customized nutritional therapies in controlling *** strategies led to significant body weight loss,improved glucolipid metabolism,and fewer prenatal and newborn *** holistic approach,which emphasizes the notion of’chrononutrition’,takes into account optimal meal timing that is in sync with circadian rhythms,as well as enhanced sleep *** tailored dietary therapy,managing meal timing,and ensuring appropriate sleep may improve results for women with GDM,opening up a possible avenue for multi-center trials.

关键词： Gestational diabetes mellitus Metabolism Nutrition Maternal-fetal health Dietary therapy

Diagnosing upper tract urothelial carcinoma: A review of the role of diagnostic ureteroscopy and novel developments over last two decades

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Asian Journal of Urology 2024年第2期11卷 242-252页

作者： Paul Gravestock Daniel Cullum bhaskar Somani Rajan Veeratterapillay Urology Department Freeman HospitalNewcastle Upon TyneUK Department of Urology University Hospital SouthamptonSouthamptonUK

Objective: The role of ureteroscopy in the diagnosis of upper tract urothelial carcinoma is yet to be fully determined. We aimed to provide an up to date evaluation of its role and the emerging technologies in the ***: A literature search of the last two decades (from 24th May, 2001 to 24th May, 2021) was carried out identifying 147 papers for potential inclusion within this narrative ***: Diagnostic ureteroscopy is undeniably useful in its ability to visualise and biopsy indeterminate lesions, and to risk stratify malignant lesions that may be suitable for kidney sparing surgery. However, an increased risk of intravesical recurrence following nephroureterectomy when a prior diagnostic ureteroscopy has been performed, inadequate sampling at biopsy, complications from the procedure, and difficult ureteric access are all potential drawbacks. Furthermore, whilst generally an accurate diagnostic procedure, it risks missing carcinoma in-situ lesions. Despite this, evidence shows that routine use of ureteroscopy changes the management of patients in a large proportion of cases, preventing unnecessary surgery or facilitating kidney sparing surgery. The overall rate of complications is low, and improved biopsy techniques and the use of tissue biomarkers for improved staging and grading are encouraging. The risks of delays to definitive management and post-ureteroscopy intravesical recurrence do not seem to affect survival, and trials are in progress to determine whether intravesical therapy can mitigate the latter. Further promising techniques are being investigated to improve shortcomings, particularly in relation to improved diagnosis of carcinoma in situ and preoperative ***: Ureteroscopy has a role in the diagnosis of upper tract malignancy, though whether it should be used routinely is yet to be determined.

关键词： Ureteroscopy Carcinoma Transitional cell Ureteralneoplasms Urinary bladder neoplasms Carcinomainsitu Biopsy

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公牛尿道骨盆区尿道切开术

动物医学进展 1980年第4期 34-36页

作者： k.bhaskar Singh 杨平川

公牛尿道骨盆区结石的清除、膀胱结石的移除和膀胱内部及膀胱壁的检查,需用仪器,例如复回器(Rao 1975)、碎石器或膀胱镜(Marekand Mocsy 1956,RosCnberser 1970)等,依情况而定,插入骨盆

关键词：尿道肛门骨盆区骨盆部泌尿生殖系统魄门躯干切开术阴茎海绵体公牛

Synthesis of plant-based biogenic jarosite nanoparticles using Azadirachta indica and Eucalyptus gunni leaf extracts and its application in Fenton degradation of dicamba

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Water Science and Engineering 2024年第2期17卷 157-165页

作者： Shivaswamy bhaskar Basavaraju Manu Marikunte Yanjarappa Sreenivasa Arlapadavu Manoj Department of Civil Engineering National Institute of Technology CalicutKozhikode 673601KeralaIndia Deparment of Civil Engineering National Instute of Techogy KamatakaSurahalP.Srinivasnaga Mangaore5725Indi Department of Studies in Microbiology University of MysoreMysuru 570006KarnatakaIndia Department of Civil Enginering Siddaganga Institute of TechnologyTumkur 572103India

Bio-jarosite,an iron mineral synthesized biologically using bacteria,is a substitute for iron catalysts in the Fenton oxidation of organic *** nanocatalysts have been widely used as Fenton catalysts because they have a larger surface area than ordinary catalysts,are highly recyclable,and can be treated *** study aimed to explore the catalytic properties of bio-jarosite iron nanoparticles syn-thesized with green methods using two distinct plant species:Azadirachta indica and Eucalyptus *** focus was on the degradation of dicamba via Fenton *** synthesized nanoparticles exhibited different particle size,shape,surface area,and chemical composition *** particles were effective in removing dicamba,with removal efficiencies of 96.8%for *** bio-jarosite iron nano-particles(ABFeNPs)and 93.0%for *** bio-jarosite iron nanoparticles(EBFeNPs)within 120 min of *** the catalyst dosage by 0.1 g/L resulted in 7.6%and 43.0%increases in the dicamba removal efficiency for EBFeNPs and ABFeNPs with rate constants of 0.025 min^(-1) and 0.023 min^(-1),respectively,confrming their catalytic ***,the high efficiency of both catalysts was demonstrated through five consecutive cycles of linear pseudo-first-order Fenton oxidation reactions.

关键词： Acidithiobacillus ferrooxidans Fenton process Jarosite Herbicide Dicamba Azadirachta indica Eucalyptus gunni

An Extensive Review of Vitiligo-Associated Conditions

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International Journal of Dermatology and Venereology 2024年第1期7卷 44-51页

作者： Madhavi Premkumar Iyshwarya bhaskar kalarani Vajagathali Mohammed Ramakrishnan Veerabathiran Human Cytogenetics and Genomics Laboratory Faculty of Allied Health SciencesChettinad Hospital and Research InstituteChettinad Academy of Research and EducationKelambakkamTamil Nadu 603103India

Vitiligo is an autoimmune disorder caused by the destruction of melanocytes in various body *** diseases may accompany *** prevalence of vitiligo varies among geographical regions and shows no relation to sex or ***,vitiligo most commonly affects people aged 10 to 30 *** clinical symptoms of vitiligo include irregular patches on the skin and various diseases associated with this *** present review focuses on the clinical effects and risk factors of vitiligo-associated conditions and the current therapeutics for treating *** systematic review was performed based on the PRISMA guidelines and articles published from 2000 to 2023 in Web of Science,PubMed,PsycINFO,and *** most clinically significant diseases associated with vitiligo are alopecia areata,autoimmune thyroid disease,Addison disease,and type 1 diabetes *** targeted population is specifically prone to vitiligo;it does not affect any particular race or ***,awareness of the diseases associated with vitiligo is necessary to control them through various medical and surgical treatments with the proper facilities.

关键词： vitiligo autoimmune disorder melanocyte Addison disease atopic dermatitis

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Transurethral resection of bladder tumor: A systematic review of simulator-based training courses and curricula

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Asian Journal of Urology 2024年第1期11卷 1-9页

作者： Panagiotis kallidonis Angelis Peteinaris Gernot Ortner kostantinos Pagonis Costantinos Adamou Athanasios Vagionis Evangelos Liatsikos bhaskar Somani Theodoros Tokas Department of Urology University Hospital of RionPatrasGreece Department of Urology and Andrology General Hospital Hall I.T.Hall in TirolAustria Medical University of Vienna ViennaAustria Department of Urology University Hospital Southampton NHS Foundation TrustSouthamptonUK

Objective:Transurethral resection of bladder tumor is one of the most common everyday urological *** kind of surgery demands a set of skills that need training and *** this review,we aimed to investigate the current literature to find out if simulators,phantoms,and other training models could be used as a tool for teaching ***:A systematic review was performed according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses statement and the recommendations of the European Association of Urology guidelines for conducting systematic *** out of 932 studies met our inclusion criteria and are presented in the current ***:The UroTrainer(karl Storz GmbH,Tuttlingen,Germany),a virtual reality training simulator,achieved positive feedback and an excellent face and construct validity by the *** inspection of bladder mucosa,blood loss,tumor resection,and procedural time was improved after the training,especially for inexperienced urologists and medical *** construct validity of UroSim®(VirtaMed,Zurich,Switzerland)was *** simulator(Samed GmbH,Dresden,Germany)was found to be a realistic and useful tool by experts and urologists with intermediate *** test objective competency model based on SIMBLA simulator could be used for evaluating *** porcine model of the Asian Urological Surgery Training and Education Group also received positive feedback by the participants that tried *** Simulation and Technology Enhanced Learning Initiative Project had an extraordinary face and content validity,and 60%of participants would like to use the simulators in the *** 5-day multimodal training curriculum“Boot Camp”in the United kingdom achieved an increase of the level of confidence of the participants that lasted months after the ***:Simulators and courses or curricula based on a simulator training could be a valuable learning tool fo

关键词： Simulator Train Curriculum Transurethral resection Vaporesection Laser Bladder

Role of virtual reality in improving the spatial perception of the kidney during flexible ureteroscopy:A feasibility study using virtual reality simulators and 3D models

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Current Urology 2024年第1期18卷 24-29页

作者： Ali Talyshinskii Bm Zeeshan Hameed Ulanbek Zhanbyrbekuly Mesrur Selcuk Silay Nithesh Naik Milap Shah Anshuman Singh Bakhman Guliev Patrick Juliebø-Jones bhaskar kumar Somani Department of Urology Astana Medical UniversityAstanaKazakhstan Department of Urology Father Muller Medical CollegeMangaloreKarnatakaIndia Department of Urology Istanbul Medeniyet UniversityIstanbulTurkey Department of Mechanical and Industrial Engineering Manipal Institute of TechnologyManipal Academy of Higher EducationManipalKarnatakaIndia Department of Urology Aarogyam Hospital AhmedabadIndia Department of Urology Kasturba Medical CollegeManipalManipal Academy of Higher EducationManipalKarnatakaIndia Department of Urology Maninsky HospitalSaint PetersburgRussia Department of Urology Haukeland University HospitalBergenNorway Department of Urology University Hospital Southampton NHS TrustSouthamptonUK

Background:The aims were to describe a software-based reconstruction of the patient-specific kidney cavity intraluminal appearance via a head-mounted device and to estimate its feasibility for training *** and methods:In total,15 novices were *** novice was shown a three-dimensional reconstruction of a patient's computed tomography scan,whose kidney was *** then joined the surgeon in the operating room and assisted them in detecting the stone during flexible ureteroscopy on the printed ***,each participant did a 7-day virtual reality(VR)study followed by virtual navigation of the printed kidney model and came to the operating room to help the surgeon with ureteroscope *** length of the procedure and the number of attempts to find the targeted calyx were ***:With VR training,the length of the procedure(p=0.0001)and the number of small calyces that were incorrectly identified as containing stones were significantly reduced(p=0.0001).All the novices become highly motivated to improve their endourological skills *** noticed minimal values for nausea and for ***,oculomotor-related side effects were defined as *** specialists noticed a good similarity between the VR kidney cavity representation and the real picture,strengthening the potential for the novice's education via VR ***:Virtual reality simulation allowed for improved spatial orientation within the kidney cavity by the novices and could be a valuable option for future endourological training and curricula.

关键词： Ureteroscopy kidney calculi Virtual reality Endourology Training Nephroscopy 3D

Defining minimal invasive surgical therapy for benign prostatic obstruction surgery: Perspectives from a global knowledge, attitude, and practice survey

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Asian Journal of Urology 2024年第1期11卷 55-64页

作者： Bryan kwun-Chung Cheng Steffi kar-kei Yuen Daniele Castellani Marcelo Langer Wroclawski Hongda Zhao Mallikarjuna Chiruvella Wei-Jin Chua Ho-Yee Tiong Yiloren Tanidir Jean de la Rosette Enrique Rijo Vincent Misrai Amy krambeck Dean S.Elterman bhaskar k.Somani Jeremy Yuen-Chun Teoh Vineet Gauhar Department of Surgery United Christian HospitalHong KongChina S.H.Ho Urology Centre Department of SurgeryPrince of Wales HospitalThe Chinese University of Hong KongHong KongChina Department of Urology University Hospital“Ospedali Riuniti”and Polytechnic University of Marche RegionAnconaItaly Hospital Israelita Albert Einstein Sao PauloSPBrazil BP—A Beneficencia Portuguesa de Sao Paulo Sao PauloSPBrazil Faculdade de Medicina do ABC Santo AndreSPBrazil Department of Urology Asian Institute of Nephrology and UrologyHyderabadTGIndia Department of Urology National University HospitalSingapore Department of Urology Marmara University School of MedicineIstanbulTurkey Department of Urology Medipol Mega University HospitalIstanbul Medipol UniversityIstanbulTurkey Department of Urology Hospital Quiron BarcelonaBarcelonaSpain Department of Urology Clinique PasteurToulouseFrance Department of Urology Indiana University School of MedicineIndianapolisINUSA Division of Urology Department of SurgeryUniversity Health NetworkUniversity of TorontoTorontoCanada Department of Urology University Hospital Southampton NHS TrustSouthamptonUK Department of Urology Ng Teng Fong General HospitalNUHSSingapore

Objective:To scrutinize the definitions of minimal invasive surgical therapy(MIST)and to investigate urologists’knowledge,attitudes,and practices for benign prostatic obstruction ***:A 36-item survey was developed with a Delphi *** on definitions of MIST and attitudes and practices of benign prostatic obstruction surgeries were *** were invited globally to complete the online *** was achieved when more than or equal to 70%responses were“agree or strongly agree”and less than or equal to 15%responses were“disagree or strongly disagree”(consensus agree),or when more than or equal to 70%responses were“disagree or strongly disagree”and less than or equal to 15%responses were“agree or strongly agree”(consensus disagree).Results:The top three qualities for defining MIST were minimal blood loss(n=466,80.3%),fast post-operative recovery(n=431,74.3%),and short hospital stay(n=425,73.3%).The top three surgeries that were regarded as MIST were Urolift®(n=361,62.2%),Rezum®(n=351,60.5%),and endoscopic enucleation of the prostate(EEP)(n=332,57.2%).Consensus in the knowledge section was achieved for the superiority of Urolift®,Rezum®,and iTIND®over transurethral resection of the prostate with regard to blood loss,recovery,day surgery feasibility,and post-operative *** in the attitudes section was achieved for the superiority of Urolift®,Rezum®,and iTIND®over transurethral resection of the prostate with regard to blood loss,recovery,and day surgery *** on both sections was achieved for EEP as the option with the better symptoms and flow improvement,lower retreatment rate,and better suitable for prostate more than 80 ***:Minimal blood loss,fast post-operative recovery,and short hospital stay were the most important qualities for defining ***®,Rezum®,and EEP were regarded as MIST by most urologists.

关键词： Benignprostate hyperplasia Minimalinvasive surgical therapy Surgery Bladderoutlet obstruction

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黏弹性核组合夹芯梁的振动和热皱折

钢结构(中英文) 2008年第4期 94-94页

作者： V.Pradeep N.Ganesan k.bhaskar

对由聚合物面层与黏弹性核构成的夹芯梁的振动和热皱折性能进行了研究。比较了夹芯板和夹芯梁的单元。将每个组合层视为一个等价的单层,假定了稳定的温度区域。公式是一个解耦的热力学公式,首先计算了梁的区域和温度,然后用于进一步的... 详细信息

对由聚合物面层与黏弹性核构成的夹芯梁的振动和热皱折性能进行了研究。比较了夹芯板和夹芯梁的单元。将每个组合层视为一个等价的单层,假定了稳定的温度区域。公式是一个解耦的热力学公式,首先计算了梁的区域和温度,然后用于进一步的计算。研究了纤维角度、比率以及核芯厚度对单元性能的作用。研究显示,对某些纤维角度,梁单元和板单元的预测结果有很大不同。

关键词：振动弯曲热衰减