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源于日常,归于寂静

现代装饰 2018年第6期 88-95页

作者： MOEBE Sonia Pedrazzini toumei studio note Swedish Ninja Anna Thorunn Zuzana Holaňová & Martina ?ílová bisqit Alberto Bellamoli Jonathan Hotz 朱妍澔 Bujnie ROY Stephen Roy Besler & Sons klong katriina Nuutinen Yoh komiyama 彭佳 UM Studio Stoft studio RINN Inc.

“不论世间如何动乱，最后终归于寂静；不论万法如何差别，最后终归于平等。”在这个错综复杂、瞬息流变的世界，我们在追求着怎样的设计？有些人无时无刻不在标榜“个性”，热衷于往自己身上贴上各式各样的“标签”，以“标新立异”作... 详细信息

“不论世间如何动乱，最后终归于寂静；不论万法如何差别，最后终归于平等。”在这个错综复杂、瞬息流变的世界，我们在追求着怎样的设计？有些人无时无刻不在标榜“个性”，热衷于往自己身上贴上各式各样的“标签”，以“标新立异”作为设计的目标：而有些人却选择沉淀内心，体察和感悟身边世界和日常生活的细微变化，在寂静中寻找设计的本质。

关键词：室内装饰设计方案设计风格设计师

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使用表皮肌电监测来检测全面强直-阵挛发作

癫痫杂志 2018年第3期4卷 249-256页

作者： Jonathan J Halford Michael R Sperling Dileep R Nair 童馨高慧慕洁 Dlugos DJ Tatum WO Harvey J French JA Pollard JR Faught E Noe kH Henry TR Jetter GM Lie ov Morgan LC Girouard MR Cardenas DP Whitmire LE Cavazos JE

该前瞻性多中心Ⅲ期临床试验的目的在于评估在癫痫监测单元(Epilepsy monitoring unit,EMU)中使用可穿戴的表皮肌电图(surface electromyographic,s EMG)监测系统来检测全面强直-阵挛发作(Generalized tonic–clonic seizures,GTCS)的性能和耐受性。199例有GTCS病史的患者被收入11个Ⅳ级癫痫中心的EMU中,在进行临床视频脑电图(VEEG)监测的同时,也通过在肱二头肌上佩戴可穿戴设备接受了s EMG监测。所有s EMG数据记录都使用先前开发的检测算法在中心站点处理。将s EMG检测到的GTCS与3名评审专家验证的发作事件进行比较。在所有受试者中,检测算法共检测到了46次GTCS中的35次[76%,95%CI(0.61,0.87)],阳性预测值(Positive predictive value,PPV)为0.03,平均误报率(False alarm rate,FAR)为2.52/24 h。对于在肱二头肌中线上方记录到的数据,系统检测到了全部的29例GTCS[100%,95%CI(0.88,1.00)],检测时间平均延迟7.70 s,PPV为6.2%,平均FAR为1.44/24 h。28%(55/199)报告了轻至中度的不良事件,并导致9%的研究中止(17/199)。这些不良事件主要是电极贴片引起的皮肤刺激反应,这种情况未经治疗即可缓解。研究中无严重不良事件报告。在肱二头肌上使用s EMG监测装置来检测GTCS是可行的。正确放置该装置对于检测准确性至关重要,但是对于一些患者而言,减少误报数仍有一定难度。

关键词：临床试验癫痫监测全面性癫痫发作痉挛大发作可穿戴

Corrigendum to “Introgression of sharp eyespot resistance from Dasypyrum villosum chromosome 2VL into bread wheat” [Crop J. 11 (2023) 1512–1520]

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Introgression of sharp eyespot resistance from Dasypyrum villosum chromosome 2VL into bread wheat

The Crop Journal 2023年第6期

作者： Caiyun Liu Wei Guo Yang Wang Bisheng Fu Jaroslav Dolezˇel Ying Liu Wenling Zhai Mahmoud Said IstvánMolnár katerˇinaHolušová Ruiqi Zhang Jizhong Wu

来源：博看期刊评论

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微阵列技术的临床应用:卵巢上皮癌中表达上调的肌酸激酶B可成为血清学标记物

The Crop Journal 2023年第5期

作者： Caiyun Liu Wei Guo Yang Wang Bisheng Fu Jaroslav Dolezel Ying Liu Wenling Zhai Mahmoud Said István Molnár katerina Holu?ová Ruiqi Zhang Jizhong Wu

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世界核心医学期刊文摘（妇产科学分册） 2005年第5期1卷 42-43页

作者： Huddleston H.G Wong k.-k WelchW.R 朱国栋

(1) To identify and (2) validate genes that are up-regulated in ovarian cance r, and (3) to investigate whether the activity of a candidate gene, creatine kin ase B (CkB) is elevated in preoperative sera from ovarian cancer patients compar ed to patients with benign pelvic masses and normal controls. MICROMAX cDNA micr oarray system and RNA derived from pooled ovarian cancer cell lines and normal o vary surface epithelial cells (HOSE) were used to identify differentially expres sed genes. Using RNA from both cell lines and from tissue obtained through laser capture microdissection (LCM), we performed quantitative PCR in order to valida te up-regulation of one of these genes, creatine kinase B (CkB). Using a commer cially available enzyme assay, CkB activity was measured in pre-op-erative ser um samples obtained from 45 ovarian cancer patients, 49 patients with a benign p elvic mass, as well as 37 normal controls. Statistical analysis was preformed us ing an unpaired Students t test. Microarray technology revealed that CkB gene expression had a cancer to HOSE ratio of 18. RNA levels of CkB, measured by real -time PCR, were elevated a mean (and standard error) of 36-fold (8.4) in cance r cell lines compared with HOSEcells and 22.75-fold (10.45) in microdissected o varian cancer epithelial cells compared with normal ovarian epithelial cells. In serum, the mean (±standard error) of CkB enzyme activity in cancer cases was 24.7 U/L units (±5.1) compared to 9.6 U/L (±1.6) for benign mass cas es (P = 0.0088) and to 8.5 U/L (1.7) for normal controls (P = 0.0096). Microarra y technology offers a method to identify tumor biomarkers with potential clinica l usefulness. Our data indicated that CkB gene expression is up-regulated in ov arian cancer cells in vitro and in vivo and that CkB enzyme activity is signific antly elevated in sera from ovarian cancer patients, including those with stage I disease. These findings suggest a potential role for CkB as a marker for early diagn

关键词：卵巢上皮癌微阵列技术正常卵巢血清学盆腔包块临床应用肿瘤患者血清酶检测早期诊断活体试验

A High Performance 4H-SiC Normally-off VJFET

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A High Performance 4H-SiC Normally-off VJFET

第4届国际电力电子及运动控制国际会议

作者： k.Tone P.Alexandrov L.Fursin M.Weiner T.Burke SiCLAB ECE DepartmentRutgers University 94 Brett RoadPiscataway NJ 08854 USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA United Silicon Carbide Inc. New Brunswick Technology Center100 Jersey Ave. Building A New Brunswick NJ 08902USA U.S. Army TACOM AMSTA-TR-R MS-121 Warren MI 48397USA

＜正＞ This paper presents the design, fabrication and characterisation of a high performance 4H-SiC normally-off, trenched and implanted vertical junction field-effect transistor （VJFET）- Devices with different trenched mesa widths were designed and their performance investigated. The fabricated VJFETs demonstrated a 3.9Ωresistance at VG=5V （with negligible gate current） and JD= 154A/cm2, corresponding to a low specific on-rcsistance of 3.7mΩcm2 for a normally-off VJFET blocking voltage up to 1,734V （at VG=ov）. The specific on-resistance is more than 200 times smaller than that of the theoretical limit of Si FETs. The figure-of-merit （FOM, Vbl2/RON-sp）, is equal to 815MW/cm2 for the demonstrated VJFET, substantially surpassing the best FOM of any kind of unipolar and bipolar SiC power switches.

关键词： SiC JFET oil-resistance figure-of-mcrit

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熊脱氧胆酸的毛细管气相色谱法测定

中国医药工业杂志 2000年第11期31卷 504-506页

作者：张弛 CHENAlice-k 彭会明夏桂珠北京医科大学分析研究室北京100083 DepartmentofClinicalDieteticsandNutrition

:改进了熊脱氧胆酸 (1)的羧基甲酯化和羟基乙酰化的衍生化条件。 CGC采用 ov- 1柱 ,氢气作载气 ,2 6 0°C(保持 5 m in)～ 2 80°C程序升温 ,升温速率为 4°C/m in,FID检测。 1在 6 .0～ 14.0μg线性良好 ,r=0 .9977;1在熊胆粉和栓剂中... 详细信息

:改进了熊脱氧胆酸 (1)的羧基甲酯化和羟基乙酰化的衍生化条件。 CGC采用 ov- 1柱 ,氢气作载气 ,2 6 0°C(保持 5 m in)～ 2 80°C程序升温 ,升温速率为 4°C/m in,FID检测。 1在 6 .0～ 14.0μg线性良好 ,r=0 .9977;1在熊胆粉和栓剂中的平均回收率分别为 98.1% (RSD=2 .3% )和 10 0 .3% (RSD =2 .6 % )

关键词：熊脱氧胆酸熊胆粉栓剂毛细管气相色谱法

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蜂斗菜(款冬)是一种有效预防偏头痛的药物

世界核心医学期刊文摘（神经病学分册） 2005年第5期1卷 34-35页

作者： Lipton R.B. Gbel H. Einhupl k.M. 袁海峰 H./Einhton A lbert Einstein College of Medicine Rousso Bldg. 1165 Morris Park Ave. Bronx NY 10461 United States Dr.

Objective: To evaluate the clinical efficacy of a standardized special root e xtract from the plant Petasites hybridus as a preventive therapy for migraine. M ethods: This is a three-arm, parallel-group, randomized trial comparing Peta sites extract 75 mg bid, Petasites extract 50 mg bid, or placebo bid in 245 pati ents with migraine. Eligible patients met International Headache Society criteri a for migraine, were ages 18 to 65, and had at least two to six attacks per mont h over the preceding 3 months. The main outcome measure was the decrease in migr aine attack frequency per month calculated as percentage change from baseline ov er a 4-month treatment period. Results: over 4 months of treatment, in the per -protocol analysis, migraine attack frequency was reduced by 48% for Petasit es extract 75 mg bid (p = 0.0012 vs placebo), 36% for Petasites extract 50 mg bid (p = 0.127 vs placebo), and 26% for the placebo group. The proportion of p atients with a ≥ 50% reduction in attack frequency after 4 months was 68% f or patients in the Petasites extract 75-mg arm and 49% for the placebo arm ( p < 0.05). Results were also significant in favor of Petasites 75 mg at 1, 2, an d 3 months based on this endpoint. The most frequently reported adverse reaction s considered possibly related to treatment were mild gastrointestinal events, pr edominantly burping. Conclusions: Petasites extract 75 mg bid is more effective than placebo and is well tolerated as a preventive therapy for migraine. Petasit es 50 mg PO bid was not significantly more effective than placebo on the primary study endpoints.

关键词：蜂斗菜头痛发作提取物国际头痛协会安慰剂临床疗效随机试验

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出生前被诊断为先天性心脏病的早产儿的转归

世界核心医学期刊文摘（儿科学分册） 2006年第8期2卷 40-41页

作者： Andrews R. E. Simpson J. M. Sharland G. k. 王一飞(译) - J. PEDIATR. 2006 148/2(213 -216) 不详

Objective:To determine outcome of delivery before 36 weeks gestation in babie s diagnosed antenatally with serious congenital heart disease(CHD).Study desig n:A retrospective database review at 2 tertiary care fetal cardiology *** of neonatal course and outcome were obtained for those antenatally diagn osed with serious CHD who were live born before 36 weeks ***:Bet ween January 1998 and December 2002,9918 women were referred for fetal echocard *** CHD was diagnosed in 1191 fetuses(12%),of which 46(4%)de livered *** gestation was 33(range 24-35)weeks,and median bi rth weight 1.56(0.50-3.59)***/karyotypic anomalies occurred in 23(50%).Twenty-six babies(57%)underwent neonatal surgery:16 a cardiac pr ocedure,5 a general surgical procedure,and 5 *** died during or after operation(31%).Two babies underwent interventional heart catheterization;bot h *** overall mortality rate was 72%.Extracardiac/karyotypic anomalies i ncreased the relative risk of death by a factor of *** hospital stay for those surviving to initial discharge was 46(2-137)***:There is a very high morbidity and mortality rate in this group,particularly for those with extracardiac/karyotypic *** should be reflected in decisions ov er elective preterm delivery and when counseling parents.

关键词：先天性心脏病出生前早产儿诊断转归平均出生体重胎儿心脏病心脏超声检查回顾性分析新生儿期