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Fish-on-Chips:unveiling neural processing of chemicals in small animals through precise fluidic control

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Neural Regeneration Research 2024年第11期19卷 2351-2353页

作者： Samuel k.H.Sy Ho k. Division of Neurology Department of Medicine and TherapeuticsFaculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Li k. Shing Institute of Health Sciences Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Department of Electrical and Electronic Engineering Faculty of EngineeringThe University of Hong KongPok Fu LamHong Kong IslandHong Kong Special Administrative RegionChina Advanced Biomedical Instrumentation Center Hong Kong Science ParkPak Shek KokNew TerritoriesHong Kong Special Administrative RegionChina Margaret k.L.Cheung Research Center for Management of Park.nsonism Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Lau Tat-chuen Research Center of Brain Degenerative Diseases in Chinese Faculty of MedicineThe Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina Gerald Choa Neuroscience Institute The Chinese University of Hong KongShatinNew TerritoriesHong Kong Special Administrative RegionChina

Precise chemical cue presentation alongside advanced brainwide imaging techniques is important to the study of chemosensory processing in ***,the dynamic nature of chemical-carrying media,such as water or air,poses a significant challenge for delivering highly-controlled chemical flow to an animal ***,contact-based cue manipulation and delivery easily shift the position of the animal subject,which is often undesirable for high-quality brain ***,more advanced interfacing tools that align with the diverse range of body part sizes of an animal,ranging from micrometer-scale neurons to meter-long limbs,are much *** is particularly crucial when dealing with dimensions that are beyond the reach of conventional experimental tools.

关键词： dealing precise sizes

Awareness of the Termination of Pregnancy Act of the Laws of Zambia among Women of Reproductive Age at k.nyama First Level Hospital in Lusak. District Zambia

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Open Journal of Obstetrics and Gynecology 2024年第8期14卷 1267-1287页

作者： J. k. Botha C. C. Ngoma P. S. Munk.k. Lusak. District Health Office Matero First Level Hospital Lusaka Zambia Department of Midwifery Womens and Child Health School of Nursing Sciences University of Zambia Lusaka Zambia College of Nursing and Midwifery University of Lusaka Lusaka Zambia

Back.round: Termination of pregnancy (TOP) in Zambia is guided by the Termination of Pregnancy (TOP) Act of 1972 and as amended in 1994 of the laws of Zambia. However, despite provision of Comprehensive abortion care services with the liberal law, statistics at k.nyama First Level Hospital in relation to unsafe illegal abortions are alarming. This study sought to understand the Awareness on the TOP Act of the laws of Zambia among women of reproductive age 15 - 49 years at k.nyama First Level Hospital in Lusak. District. Purpose of the Study: To assess awareness on the TOP Act among women of reproductive age at k.nyama First Level Hospital in Lusak., Zambia. Methodology: A convergent parallel mixed method design was conducted using both survey and in-depth interviews among women of reproductive age at k.nyama First Level Hospital in Lusak. District. The study surveyed 370 randomly sampled women aged 15 to 49 years old while the in-depth interviews included eight women purposively sampled from the survey population. Survey data was analyzed using descriptive and inferential statistics while qualitative data thematic analysis was used. Results: The study found that 37% of the participants were aware of the TOP Act while 63.8% viewed legalization of abortion for any reason as wrong. The study results also showed that widowed women were 8 times more lik.ly to be aware of the TOP Act compared to single women (AOR: 8.262;95% CI: 1.105, 61.778). Women in business were significantly more lik.ly to be aware of the TOP Act compared to those who reported having no occupation. (AOR: 2.61;95% CI: 1.246, 5.499). Limited access to information, the social stigma attached to abortion, health care providers’ attitudes, cultural norms, values and religious beliefs, restrictive legal requirements, and absence of a supportive network.were some of the barriers affecting awareness and utilization of available safe abortion care services. Conclusions: The research findings concluded that a

关键词： Awareness Termination of Pregnancy Act Barriers Determinants Women

Sequential decay analysis of^(235)U(n^(th),f)reaction using fragmentation approach

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Chinese Physics C 2024年第6期48卷 145-154页

作者： Nitin Sharma Ashutosh k.ushik.Manoj k.Sharma School of Physics and Materials Science Thapar Institute of Engineering&TechnologyPatiala-147004PunjabIndia

Numerous experimental and theoretical observations have concluded that the probability of the three fragment emission(ternary fission)or binary fission increases when one proceeds towards the heavy mass region of nuclear periodic *** factors affect fragment emission,such as the shell effect,deformation,orientation,and fissility *** and ternary fissions are observed for both ground and excited states of the *** collinear cluster tripartition(CCT)channel of the^(235)U(n^(th),f)reaction is studied,and we observe that the CCT may be a sequential or simultaneous emission *** date,different approaches have been introduced to study the CCT process as a simultaneous or sequential process,but the decay dynamics of these modes have not been not fully *** the three fragments of the sequential process and exploring their related dynamics using an excitation energy dependent approach would be of further ***,in this study,we investigate the sequential decay mechanism of the^(235)U(n^(th),f)reaction using quantum mechanical fragmentation theory(QMFT).The decay mechanism is considered in two steps,where initially,the nucleus splits into an asymmetric *** the second step,the heavy fragment obtained in the first step divides into two *** I analysis is conducted by calculating the fragmentation potential and preformation probability for the spherical and deformed choices of the decaying *** most probable fragment combination of stage I are identified with respect to the dips in the fragmentation structure and the corresponding maxima of the preformation probability(P0).The light fragments of the identified decay channels(obtained in step I)agree closely with the experimentally observed *** excitation energy of the decay channel is calculated using an iteration *** excitation energy is shared using an excitation energy dependent level density *** obtained excitation

关键词： fission cluster radioactivity ternary fission spontaneous fission cluster model total k.netic energy preformation probability

The diagnostic conundrum in necrotizing otitis externa

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World Journal of Otorhinolaryngology-Head and Neck.Surgery 2024年第1期10卷 59-65页

作者： Abiya A.Ahmed Shaan Rashid Vinay k.Gupta Neil C.Molony k.shav k.Gupta Bradford Royal Infirmary Bradford Teaching Hospitals NHS Foundation TrustWest BromwichWest YorkshireUK Sandwell and West Birmingham Hospitals NHS Trust West BromwichUK Russells Hall Hospital DudleyUK

Necrotizing otitis externa(NOE)is an aggressive and fast‐evolving infection of the external auditory *** diagnoses and untreated cases can lead to severe,even fatal consequences and so early diagnosis and treatment are *** is a notoriously challenging diagnosis to *** is therefore important to understand what diagnostic modalities are available and how otolaryngologists can use them to accurately treat such an aggressive *** review aims to evaluate the different diagnostic options available in NOE and discuss their advantages and limitations,thus,providing an up‐to‐date picture of the multimodal approach required in the diagnosis of this disease.

关键词： diagnostic malignant otitis externa necrotizing osteomyelitis sk.ll base osteomyelitis temporal bone osteomyelitis

Characterization of Small-Scale Farmers and Assessment of Their Access to Crop Production Information in Selected Counties of k.nya

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Agricultural Sciences 2024年第5期15卷 565-589页

作者： Anastasia Mumbi Wahome John B. k. k.ema Galcano C. Mulak. Isaac Muk.k. Department of Geospatial & Space Technology University of Nairobi Nairobi Kenya Department of Public Health Kenya Methodist University Nairobi Kenya

Small-scale farming accounts for 78% of total agricultural production in k.nya and contributes to 23.5% of the country’s GDP. Their crop production activities are mostly rainfed subsistence with any surplus being sold to bring in some income. Timely decisions on farm practices such as farm preparation and planting are critical determinants of the seasonal outcomes. In k.nya, most small-scale farmers have no reliable source of information that would help them mak. timely and accurate decisions. County governments have extension officers who are mandated with giving farmers advisory services to farmers but they are not able to reach most farmers due to facilitation constraints. The mode and format of sharing information is also critical since it’s important to ensure that it’s timely, well-understood and usable. This study sought to assess access to geospatial derived and other crop production information by farmers in four selected counties of k.nya. Specific objectives were to determine the profile of small-scale farmers in terms of age, education and farm size;to determine the type of information that is made available to them by County and Sub-County extension officers including the format and mode of provision;and to determine if the information provided was useful in terms of accuracy, timeliness and adequacy. The results indicated that over 80% of the farmers were over 35 years of age and over 56% were male. Majority had attained primary education (34%) or secondary education (29%) and most farmers in all the counties grew maize (71%). Notably, fellow farmers were a source of information (71%) with the frequency of sharing information being mostly seasonal (37%) and when information was available (43%). Over 66% of interviewed farmers indicating that they faced challenges while using provided information. The results from the study are insightful and helpful in determining effective ways of providing farmers with useful information to ensure maximum benefits.

关键词： Small Scale Farmers Farmers Crop Production Information Services Geospatial Information Information Access

Stability and Generalization of Hypergraph Collaborative Network.

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Machine Intelligence Research 2024年第1期21卷 184-196页

作者： Michael k.Ng Hanrui Wu Andy Yip Institute of Data Science The University of Hong KongHong KongChina Department of Mathematics The University of Hong KongHong KongChina College of Information Science and Technology Jinan UniversityGuangzhou 510006China

Graph neural network. have been shown to be very effective in utilizing pairwise relationships across ***,there have been several successful proposals to generalize graph neural network. to hypergraph neural network. to exploit more com-plex *** particular,the hypergraph collaborative network. yield superior results compared to other hypergraph neural net-work. for various semi-supervised learning *** collaborative network.can provide high quality vertex embeddings and hyperedge embeddings together by formulating them as a joint optimization problem and by using their consistency in reconstructing the given *** this paper,we aim to establish the algorithmic stability of the core layer of the collaborative network.and provide generaliz--ation *** analysis sheds light on the design of hypergraph filters in collaborative network.,for instance,how the data and hypergraph filters should be scaled to achieve uniform stability of the learning *** experimental results on real-world datasets are presented to illustrate the theory.

关键词： Hypergraphs vertices hyperedges collaborative network. graph convolutional neural network.(CNNs) stability generalization guarantees

Study of Secondary Cosmic Rays and Astronomical X-Ray Sources using Small Stratospheric Balloons

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Research in Astronomy and Astrophysics 2024年第6期24卷 94-109页

作者： Rupnath Sik.ar Sandip k.Chak.abarti Debashis Bhowmick Indian Centre for Space Physics 466BarakholaSingabari RoadNetai NagarKolkata700099West BengalIndia

The X-ray sources of the universe are extraterrestrial in nature which emit X-ray *** closest strong X-ray source is the Sun,which is followed by various compact sources such as neutron stars,black.holes,the Crab pulsar,*** this paper,we analyze the data received from several low-cost lightweight meteorological balloon-borne missions launched by the Indian Centre for Space *** main interest is to study the variation of the vertical intensity of secondary cosmic rays,the detection of strong X-ray sources,and their spectra in the energy band of^(1)0–80 k.V during the complete *** to the lack.of an onboard pointing system,low exposure time,achieving a maximum altitude of only~42 k.,and freely rotating the payload about its axis,we modeled the back.round radiation flux for the X-ray detector using physical *** also present the source detection method,observation of the pulsation of the Crab(^(3)3 Hz),and spectra of some sources such as the quiet Sun and the Crab pulsar.

关键词： X-rays:stars balloons instrumentation:detectors

SARS-CoV-2 and innate immunity:the good,the bad,and the"goldilock."

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Cellular & Molecular Immunology 2024年第2期21卷 171-183页

作者： Benjamin L.Sievers Mark.T.k.Cheng k.ta Csiba Bo Meng Ravindra k.Gupta Department of Medicine University of CambridgeCambridgeUK Cambridge Institute of Therapeutic Immunology&Infectious Disease(CITID) Department of MedicineUniversity of CambridgeCambridgeUk

An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of *** about this interplay can not only help us identify biological mechanisms but also reveal pathogen vulnerabilities that can be leveraged *** humoral response to SARS-CoV-2 infection has been the focus of intense research,and the role of the innate immune system has received significantly less ***,we review current k.owledge of the innate immune response to SARS-CoV-2 infection and the various means SARS-CoV-2 employs to evade innate defense *** also consider the role of innate immunity in SARS-CoV-2 vaccines and in the phenomenon of long COVID.

关键词： SARS-CoV-2 Innate immune response Interferon Cytok.nes Inflammation Antiviral targets

Cool white light and tunable multicolor emission from Tb^(3+)/Dy^(3+)co-activated glasses under different excitations for WLEDs

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Journal of Rare Earths 2024年第1期42卷 46-56,I0002页

作者： L.Vijayalak.hmi k.Naveen k.mar Jong Dae Baek Department of Automotive Engineering Yeungnam UniversityGyeongsanGyeongbuk38541Republic of Korea Department of Mechanical Engineering Yeungnam UniversityGyeongsan38541Republic of Korea

A set of co-doped(Tb^(3+)/Dy^(3+))lithium zinc borate(LZB)glasses were developed by melt *** structural evaluation was performed for synthesized glassy *** Dy^(3+)and Tb^(3+)individually doped glasses exhibit intense yellow and green luminescence bands at 575 nm(^(4)F_(9/2)→^(6)H_(13/2))and543 nm(^(5)D_(4)→^(7)F_(5)),*** sensitization effect of Dy^(3+)on Tb^(3+)was analyzed by increasing the Tb^(3+)content with respect to the optimum Dy^(3+)content(0.5 mol%)in Dy^(3+)/Tb^(3+).The spectral overlay of Dy^(3+)luminescence and Tb^(3+)absorption profiles,Dy^(3+)/Tb^(3+)PL spectra under different excitations 352,362,376,and 385 nm,shortening decay lifetimes of Dy^(3+)in Dy^(3+)/Tb^(3+)co-activated glasses,energy transfer(ET)parameters,chromaticity coordinates and their corresponding correlated temperatures all help to explain ET from Dy^(3+)to Tb^(3+).At 385 nm of Dy^(3+)excitation,the optimized co-activated(0.5Dy^(3+)+1.0Tb^(3+)):LZB glass displays cool white light *** non-radiative ET from Dy^(3+)to Tb^(3+)is dominated by electric dipole-dipole interaction and its ET efficiency was calculated to be 63%.At the same time,reverse ET from Tb^(3+)to Dy^(3+)was also *** shift in color coordinates from dominant yellow to greenish-yellow,green and white light emission suggests that Dy^(3+)/Tb^(3+)coactivated LZB glasses can be a potential candidate for UV converted multicolor and white light emitting devices.

关键词： Rare earths Photoluminescence Energy transfer Spectral overlap Decay lifetime Multicolor emitting LEDs