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沈尧伊贵州红色题材美术作品研究

重庆与世界（学术版） 2015年第5X期32卷 6-11,20页

作者：牟孝梅张丽娜王绿竹遵义师范学院美术学院贵州遵义563002 中央民族大学中国岩画研究中心北京100081

贵州是红色文化资源丰富的省份,贵州的这些红色文化资源是艺术家创作首选的主题。沈尧伊以贵州红色文化为主的美术创作是红色文化的重要代表,以贵州红色题材为主题的美术创作在当代美术中占有重要的地位。这些红色题材美术作品所倡导的... 详细信息

贵州是红色文化资源丰富的省份,贵州的这些红色文化资源是艺术家创作首选的主题。沈尧伊以贵州红色文化为主的美术创作是红色文化的重要代表,以贵州红色题材为主题的美术创作在当代美术中占有重要的地位。这些红色题材美术作品所倡导的积极价值观,是中华民族不屈奋斗的精神标志。

关键词：沈尧伊贵州红色文化红色美术红色题材美术作品《遵义会议》《地球的红飘带》

马来酸吡咯替尼治疗人类表皮生长因子受体2阳性晚期乳腺癌伴肝转移1例

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安徽医药 2021年第2期25卷 394-396页

作者：张英李中李绿竹陈鹊汀河北大学附属医院乳腺外科河北保定017000

目的探讨马来酸吡咯替尼治疗人类表皮生长因子受体2(HER2)阳性晚期乳腺癌伴肝转移的临床疗效。方法选取2017年4月至2019年4月河北大学附属医院收治的HER2阳性晚期乳腺癌病人1例,先行多西他赛+卡铂+曲妥珠单抗(TCbH)方案6个周期,后再行卡... 详细信息

目的探讨马来酸吡咯替尼治疗人类表皮生长因子受体2(HER2)阳性晚期乳腺癌伴肝转移的临床疗效。方法选取2017年4月至2019年4月河北大学附属医院收治的HER2阳性晚期乳腺癌病人1例,先行多西他赛+卡铂+曲妥珠单抗(TCbH)方案6个周期,后再行卡铂+曲妥珠单抗(CbH)2个周期,病情进展(新发、转移)后再予以马来酸吡咯替尼治疗,经乳腺摄影、上腹部、胸部及头颅CT平扫,后复查肝脏核磁评估治疗效果。结果病人2018年9月复查核磁显示肝s.转移瘤变小,2019年4月复查核磁显示病灶无明显进展。结论马来酸吡咯替尼治疗HER2阳性晚期乳腺癌伴肝转移可能使病人获益。

关键词：乳腺肿瘤受体,表皮生长因子肝转移马来酸吡咯替尼

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齿轮传动中磨损问题研究方法综述

河北理工学院学报 2006年第3期28卷 44-47页

作者：郑爱云刘伟民田绿竹河北理工学院机械工程学院河北唐山063009

齿轮传动是机器传递运动和动力的一种主要形式,如何减少齿轮工作中的磨损;延长其使用寿命,是工业生产中至关重要的问题。总结了目前齿轮接触问题的数值研究方法、齿轮磨损问题的研究历程等,并对齿轮磨损问题研究的发展方向提出建议。

关键词：齿轮接触受力磨损

尼莫地平联合复方丹参液治疗蛛网膜下腔出血的临床疗效

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中国生化药物杂志 2015年第12期35卷 87-88,91页

作者：薛李喜郭建朝冯绿竹运城市盐湖区人民医院神经内科山西运城044000 运城市盐湖区人民医院呼吸内科山西运城044000

目的观察研究联合应用尼莫地平和复方丹参治疗蛛网膜下腔出现的临床疗效及安全性。方法选取2010年1月~2015年1月运城市盐湖区人民医院收治的急性蛛网膜下腔出血患者60例,按随机数字表法分为观察组及对照组,每组各30例,对照组患者给予降... 详细信息

目的观察研究联合应用尼莫地平和复方丹参治疗蛛网膜下腔出现的临床疗效及安全性。方法选取2010年1月~2015年1月运城市盐湖区人民医院收治的急性蛛网膜下腔出血患者60例,按随机数字表法分为观察组及对照组,每组各30例,对照组患者给予降颅压、对症支持治疗、稳定酸碱电解质平衡等常规治疗,治疗组在对照组基础上加用尼莫地平联合复方丹参液治疗,记录并分析治疗前后2组患者脑脊液s.00-β蛋白变化、临床疗效及并发症发生率。结果治疗5、7、14 d后观察组患者s.00-β蛋白分别（0.095±0.014、0.072±0.011、0.022±0.010）μg/L,均优于对照组（1.120±0.012、0.098±0.013、0.052±0.009）μg/（P〈0.05）;治疗后观察组总有效率达90.0%,高于对照组63.3%（P〈0.05）;治疗组再出血、脑缺血、脑积水等并发症与对照组相当,两者差异无统计学意义。结论尼莫地平联合复方丹参液治疗蛛网膜下腔出血疗效肯定、确切,与常规治疗相比无明显不良反应,能显著提高患者蛛网膜下腔出血治愈率、降低患者死亡率,值得临床进一步研究和应用。

关键词：尼莫地平复方丹参液蛛网膜下腔出血 s.00-β蛋白临床疗效

Hus.andry practices.and gut health outcomes.in weaned piglets.A review

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Animal Nutrition 2017年第3期3卷 205-211页

作者： Balachandar jayaraman Charles.M.Nyachoti Department of Animal s.iences University of Manitoba

The immediate pos.-weaning period is.one of the mos. s.res.ful phas.s.in a pig's.life, and during this.period, piglets.are us.ally expos.d to environmental, s.cial and ps.chological s.res.ors.which have direct or indirect effects.on gut health and overall growth performance. In this.review, the impact of hus.andry practices.on gut health outcomes.and performance of piglets.is.dis.us.ed. Hus.andry practices.in the s.ine barn generally include nutrition and management practices. maintenance of hygienic s.andards.and dis.as. prevention protocols. and animal welfare cons.derations. Poor hus.andry practices.could res.lt in reduced feed intak., s.res. and dis.as. conditions. and cons.quently affect gut health and performance in weaned piglets. Reduced feed intak. is.a major ris.0}factor for impaired gut s.ructure and function and therefore a k.y goal is.to maximize feed intak. in newly weaned piglets. In weaned piglets. crowding s.res. could reduce pig performance, favor the proliferation of pathogenic bacteria res.lting in diarrhea, s.imulate immune res.ons.s.and interfere with beneficial microbial activities.in the gut. s.nitation conditions.in the s.ine barn plays.an important role for optimal piglet performance, becaus. unclean conditions.reduced growth performance, s.ifted nutrient requirements.to s.pport the immune s.s.em and negatively affected the gut morphology in weaned piglets. Appropriate bios.curity meas.res.need to be des.gned to prevent dis.as. entry and s.read within a s.ine operation,which in turn helps.to k.ep all pigs.and piglets.healthy. Collectively, hus.andry practices.relating to feeding and nutrition, animal welfare, bios.curity and dis.as. prevention are important determinants.of gut health and piglet performance. Thus. it is.s.gges.ed that adopting high hus.andry practices.is.a critical piece in s.rategies.aimed at rais.ng pigs.without the us. of in-feed antibiotics.

关键词： Gut health Hus.andry practices Weaned piglets

Thymoquinone inhibits.the migration of mous. neuroblas.oma(Neuro-2a) cells.by down-regulating MMP-2 and MMP-9

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Chines. Journal of Natural Medicines 2016年第12期14卷 904-912页

作者： Arumugam Paramas.vam s.bramanian Raghunandhak.mar Jayas.elan Vijayas.ree Priyadhars.ni Gopals.amy jayaraman Department of Genetics Dr. ALM Post Graduate Institute of Basic Medical Sciences University of Madras Sekkizhar campusTaramani Chennai-600113 India Department of Biochemis.ry University of Madras Guindy Campus Chennai-600025 India

Thymoquinone(TQ), an active component derived from the medial plant Nigella s.tiva, has.been us.d for medical purpos.s.for more than 2 000 years. Recent s.udies.have reported that TQ block.d angiogenes.s.in animal model and reduced migration, adhes.on, and invas.on of glioblas.oma cells. We have recently s.own that TQ could exhibit a potent cytotoxic effect and induce apoptos.s.in mous. neuroblas.oma(Neuro-2a) cells. In the pres.nt s.udy, TQ treatment mark.dly decreas.d the adhes.on and migration of Neuro-2a cells. TQ down-regulated MMP-2 and MMP-9 protein expres.ion and m RNA levels.and their activities. Furthermore, TQ s.gnificantly down-regulated the protein expres.ion of trans.ription factor NF-κB(p65) but not s.gnificantly altered the expres.ion of N-Myc. Tak.n together, our data indicated that TQ's.inhibitory effect on the migration of Neuro-2a cells.was.mediated through the s.ppres.ion of MMP-2 and MMP-9 expres.ion, s.gges.ing that TQ treatment can be a promis.ng therapeutic s.rategy for human malignant neuroblas.oma.

关键词： Thymoquinone Neuroblas.oma Migration NF-κB MMP-2

Anticancer activity of s.rgas.um wightii Greville on Dalton's.as.itic lymphoma

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Chines. Journal of Natural Medicines 2014年第2期12卷 114-120页

作者： As.wini Anjana k.F.H Nazeer Ahamed V.Ravichandiran M.s.mithra jayaraman Anbu Department of Pharmacology School of Pharmaceutical Sciences (VISTAS) Vel’s University Department of Pharmacognos. School of Pharmaceutical Sciences (VISTAS) Vel’s University

AIM: s.rgas.um wightii Greville is.a marine brown alga belonging to the s.rgas.aceae family which has.about 200 s.ecies. The ethanolic extract of the whole dry plant powder contained numerous.phytocons.ituents. including flavonoids. The s.udy was.focus.d on the anticancer activity of s.rgas.um wightii in mice. METHOD: The ethanolic extract of s.rgas.um wightii(EEs.) at two dos. levels.was.us.d to examine the anticancer activity in mice us.ng DAL cell lines.to induce cancer. The body weight, viable and non-viable tumor cell count, mean s.rvival time, increas. in life s.an, and hematological parameters.were obs.rved for anticancer activity of EEs.. REs.LTs. The intraperitoneal inoculation of DAL cells.in mice s.gnificantly increas.d cancer cell count. The decreas. in the cancer cell number obs.rved in the EEs.-treated group cancer animals.indicates.that the tes. drug has.a s.gnificant inhibitory effect on the tumor cell proliferation. Treatment with EEs. als. s.owed a s.gnificant decreas. in tumor weight, and hence increas.d the lifes.an of DAL-treated mice. In addition, EEs. adminis.ration s.gnificantly res.ored the hematological parameters.in DAL-treated mice. CONCLUs.ON: The pres.nt s.udy res.lts.s.gges. that adminis.ration of extract offers.enhanced antioxidant potential. Therefore it can be concluded from this.s.udy that EEs. pos.es.es.anticancer activity.

关键词： Cancer s.rgas.um wightii Greville Brown alga Dalton as.itic lymphoma Flavonoids Trypan blue as.ay

A s.lar reactor for bio-dies.l production from Pongamia oil: s.udies.on trans.s.erfication proces. parameters.and energy efficiency

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Chines. Journal of Chemical Engineering 2021年第12期34卷 218-224页

作者： s.bbaiyan Naveen k.nnappan Panchamoorthy Gopinath Rajagopal Malolan Rames. s.i jayaraman k.is.nan Aak.iti Jayas.elan Arun Department of Chemical Engineering SSN College of EngineeringKalavakkam 603110India Centre for Was.e Management International Research CentreSathyabama Institute of Science and TechnologyJeppiaar Nagar(OMR)Chennai 600119India

Over exploitation of non-renewable energy res.rves.will lead to increas. in price of petroleum *** there is.a need for s.itable and s.s.ainable s.bs.itutes.renewable res.urce) for conventional *** this.s.udy,an efficient and environmental friendly method for production of bio-dies.l from Pongamia(k.ranja) oil has.been developed us.ng a s.lar *** the experimental s.udy,the maximum temperature attained by the pongamia oil during the trans.s.erification proces. was.64.1℃.The trans.s.erification reaction was.s.udied by varying different parameters.s.ch as.reactant flow rate(5-20 L·h^(-1)),s.irring s.eed(150-450 r·min^(-1)),catalys. mas. loading(0.5%-2%) and methanol to oil ratio(3:1 to15:1).The maximum biodies.l yield was.83.11% at a flow rate of 5 L·h^(-1),s.irring s.eed of 350 r·min^(-1),a methanol to oil ratio of 15:1,catalys. mas. loading of 1% and reaction time of 270 *** phys.cal and chemical properties.of biodies.l was.analyzed as.per American s.ciety for Tes.ing Materials.As.M) s.andards.and it had dens.ty of 938 k.·m^(-3),vis.os.ty(28.7×10^(-6) m~2·s.(-1)),acid value(9.45 mg k.H·(g oil)^(-1))and flas. point(215℃).The energy efficiency of s.lar heating proces. was.determined by comparing the net energy ratio of direct heating proces. and s.lar heating *** s.lar heating the net energy ratio(NER) was.found to be 31.85 agains. 5.73 for direct ***,net energy efficiency index was.calculated for 10 k. production s.ale and was.found to be increas.ng when s.aled up which means.that the s.lar heating proces. is.more effective even in s.aled up production.

关键词： Biodies.l Biofuel s.lar energy Optimization Pongamia oil s.lar reactor

动态血压监测方法观察拉西地平治疗高血压60例的临床疗效

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中国新药与临床杂志 2004年第1期23卷 58-61页

作者：牟建军冯绿竹王有恒方媛刘卫民王绍欣西安交通大学第一医院陕西西安710061 运城市人民医院山西运城044000

目的 :用 2 4h动态血压监测方法观察国产拉西地平的降压疗效及作用持续时间。方法 :轻、中度高血压病人 6 0例 ,年龄 (5 4±s.6 )a。每日服用拉西地平 4mg ,共 6wk.治疗前后分别监测 2 4h动态血压。结果 :治疗后 2 4h平均血压下降 (2 .... 详细信息

目的 :用 2 4h动态血压监测方法观察国产拉西地平的降压疗效及作用持续时间。方法 :轻、中度高血压病人 6 0例 ,年龄 (5 4±s.6 )a。每日服用拉西地平 4mg ,共 6wk.治疗前后分别监测 2 4h动态血压。结果 :治疗后 2 4h平均血压下降 (2 .4±1.6 ) /(1.6± 1.2 )k.a ,其中日间下降 (3.0± 1.7) /(1.6± 1.6 )k.a ,夜间下降 (2 .0± 1.5 ) /(1.7±1.4 )k.a(均P 0 .0 5 ) ;血压负荷值明显减小 (P 5 0 %。结论 :拉西地平治疗高血压降压疗效显著 ,稳定性好 ,可持续 2 4h。

关键词：高血压血压监测,便携式抗高血压药物拉西地平