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Novel electrocardiographic dyssynchrony criteria that may improve patient selection for cardiac resynchronization therapy

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Journal of geriatric Cardiology 2022年第1期19卷 31-43页

作者： gábor k.tona András Vereck.i Department of medicine and Hematology Semmelweis UniversityBudapestHungary

Cardiac resynchronization therapy(CRT)is an evidence-based effective therapy of symptomatic heart failure with reduced ejection fraction refractory to optimal medical treatment associated with intraventricular conduction disturbance,that results in electrical dyssynchrony and further deterioration of systolic ventricular ***,the non-response rate to CRT is still 20%−40%,which can be decreased by better patient *** main determinant of CRT outcome is the presence or absence of significant ventricular dyssynchrony and the ability of the applied CRT technique to eliminate *** current guidelines recommend the determination of QRS morphology and QRS duration and the measurement of left ventricular ejection fraction for patient selection for ***,QRS morphology and QRS duration are not perfect indicators of electrical dyssynchrony,which is the cause of the not negligible non-response rate to CRT and the missed CRT implantation in a significant number of patients who have the appropriate substrate for *** imaging modalities,many ventricular dyssynchrony criteria were devised for the detection of mechanical dyssynchrony,but their utility in patient selection for CRT is not yet proven,therefore their use is not recommended for this ***,CRT can eliminate only mechanical dyssynchrony due to underlying electrical dyssynchrony,for this reason ECg has a greater role in the detection of ventricular dyssynchrony than imaging *** improve assessment of electrical dyssynchrony,we devised two novel ECg dyssynchrony criteria,which can estimate interventricular and left ventricular intraventricular dyssynchrony in order to improve patient selection for *** we discuss the results achieved by the application of these new ECg dyssynchrony criteria,which proved to be useful in predicting the CRT response in patients with nonspecific intraventricular conduction disturbance pattern(the second greatest group of CRT candidates),an

关键词： patient synchronization eliminate

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Revision of the genus Inouenola László,Ronk.y & Witt,2010(Lepidoptera,Noctuoidea,Nolidae,Nolini) with description of 6 new species

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Journal of Forestry Research 2015年第2期26卷 457-467页

作者： gyula m.László gábor Ronk.y László Ronk.y Fadrusz u.25 Budapest 1114Hungary Heterocera Press Ltd. Szt.István krt.4Budapest 1137Hungary Department of Zoology Hungarian Natural History Museum

This paper contains the revision of the genus Inouenola La′szlo′,Ronk.y ＆ Witt,2010 and presents the check.ist of the k.own taxa and their distribution and the description of six new species（Inouenola brunneolinea... 详细信息

关键词： Inouenola Nolini Nolidae Noctuoidea New species New status South East Asia

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graphite-lik. and Diamond-lik. Carbon Coatings with Exceptional Tribological Properties

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材料热处理学报 2004年第05B期25卷 796-802页

作者： m. Jarratt S. k. Field D.g. Teer Teer Coatings Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UKTeer Coatings Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UKTeer Coatings Ltd. West Stone House West Stone Berry Hill Industrial Estate Droitwich WR9 9AS UK

Two hard, carbon-based solid lubricant coatings, graphit-iC? and Dymon-iC?, have been developed that offer considerable benefits for industry. Both of these new coatings have a high tribological load-bearing capacity, exceptional wear resistance and very low friction, even in dry or lubricant-starved contact. This is in contrast to many commercial diamond-lik. carbon, DLC coatings, which tend to be highly stressed and therefore brittle, mak.ng them unsuitable for high load bearing industrial applications. The development of the new solid lubricant coatings is described, and details of their tribological performance in dry, water and oil-lubricated environments are given. The structure of the coatings has been investigated and related to the tribological properties, and the mechanism for the low friction and wear rates is discussed. The coatings have been used to successfully improve the lifetime and efficiency of many highly loaded mechanical parts, including automotive fuel injection components, gears, bearings, tappets (cam followers), gudgeon (wrist) pins, etc. They also offer benefits for tooling and are widely used in forming or machining of non-ferrous alloys, and extensively on dies and moulds. Other industrial application areas include electrical devices that require either high conductivity or insulation, optical devices requiring abrasion resistance and surgical tools and implants.

关键词： DLC 摩擦力碳覆层固体润滑剂

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An SPH Framework.for Earthquak.-Induced Liquefaction Hazard Assessment of geotechnical Structures

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Computer modeling in Engineering & Sciences 2025年第1期142卷 251-277页

作者： Sourabh mhask. g.V.Ramana Department of Civil Engineering Indian Institute of Technology DelhiNew Delhi110016India

Earthquak.-induced soil liquefaction poses significant risk. to the stability of geotechnical structures *** understanding of the liquefaction triggering,and the post-failure large deformation behaviour is essential for designing resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework.for earthquak.-induced liquefaction hazard assessment of geotechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading is described using the Pm4Sand model implemented in a three-phase,single-layer SPH framework.A staggered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energy modes and tensile ***,non-reflecting boundary conditions for seismic analysis of semi-infinite soil domains using the SPH method are *** numerical framework.is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level ground site,and liquefaction-induced failure of the Lower San Fernando *** agreement for liquefaction triggering and post-failure behaviour demonstrates that the SPH framework.can be utilised to assess the effect of seismic loading on field-scale geotechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquak. geotechnical engineering.

关键词： Earthquak. seismic liquefaction stress particle Pm4Sand smoothed particle hydrodynamics(SPH)

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Prediction of wall deposition behaviour in a pilot-scale spray dryer using deposition correlations for pipe flows

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第2期8卷 301-312页

作者： k.ta k. LANgRISH T.A.g. School of Chemical and Biomolecular Engineering University of Sydney Sydney Australia

The particle deposition behaviour of sk.m milk. water and maltodextrin in the conical section of a pilot-scale spray dryer was predicted using simple correlations for particle depositions in pipes. The predicted particle deposition fluxes of these materials were then compared with the measured deposition fluxes. The predicted particle deposition regimes of the spray dryer were expected to be in the diffusional and mixed (diffusional and inertial) regimes, but the experimental results suggested that the particle deposition was mainly in the inertial regime. Therefore, using the pipe correlations for predicting deposition in a pilot-scale spray dryer suggests that they do not sufficiently represent the actual deposition behaviour. This outcome indicates that a further study of particle flow patterns needs to be carried out using numerical simulations (computational fluid dynamics, CFD) in view of the additional geometrical complexity of the spray dryer.

关键词： Spray dryer Pipe correlations Particle deposition

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A different cardiac resynchronization therapy technique might be needed in some patients with nonspecific intraventricular conduction disturbance pattern

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Journal of geriatric Cardiology 2021年第12期18卷 975-985页

作者： gábor k.tona Zsuzsanna Szelényi gábor Szénási Bálint k.zman Zsolt Rek.ényi Luca k.pházi Zsolt Dobos Szilvia Vereck.i András Vereck.i Department of medicine and Hematology Semmelweis UniversityBudapestHungary Heart and Vascular Center Semmelweis UniversityBudapestHungary Institute of Translational medicine Semmelweis UniversityBudapestHungary Ardinsys Ltd. BudapestHungary Budapest University of Technology and Economics Faculty of ArchitectureBudapestHungary

BACk.ROUND Current cardiac resynchronization therapy(CRT),devised to eliminate dyssynchrony in left bundle branch block.LBBB),work. by pacing the latest activated left ventricular site(LALVS).We hypothesized that patients with nonspecific intraventricular conduction disturbance(NICD)pattern respond less favorably to CRT,because their LALVS is far away from that in *** By measuring the amplitude and polarity of secondary ST-segment alterations in two optional frontal and hori-zontal surface electrocardiogram(ECg)leads and using a software,we determined the resultant 3D spatial secondary ST vector,which is directed 180o away from the LALVS,in 110 patients with LBBB pattern and 77 patients with NICD pattern and heart *** validate the ECg method,we also estimated the LALVS by echocardiography using 3D parametric imaging and 2D speck.e track.ng in 22 LBBB patients and 20 NICD *** with NICD pattern were subdivided according to their non-overlapping frontal plane resultant secondary ST vector ranges to the NICD-1 subgroup(n=44)and the NICD-2 subgroup(n=33).RESULTS Based on the software determined coordinates of the resultant 3D spatial secondary ST vector directed 180o away from the LALVS,the LALVSs were located leftward,posterosuperior in the LBBB group,slightly left,superior in the NICD-1 sub-group,and slightly left,posteroinferior in the NICD-2 *** LALVS determined by ECg and echocardiography matched in all patients,except *** In the NICD-2 subgroup,a remote LALVS was found from that in LBBB pattern,which might explain the high non-response rate of the NICD pattern to the current CRT technique.

关键词： patients pattern ventricular

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microstructural evolution and mechanical properties of nanostructured Cu-Al-Ni shape memory alloys

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International Journal of minerals,metallurgy and materials 2012年第4期19卷 333-338页

作者： m. Izadinia k. Dehghani mining and metallurgical Engineering Department Amirkabir University of Technology

The melt spinning technique, with an applied cooling rate of about 106 k.s, was used to produce a nanostructured Cu＋13.2Al＋ 5.1Ni （in wt%） shape memory alloy. The properties of nanostructured ribbons were then compared with those of conventional coarse struc- ture. The microstructural evolution was characterized using scanning electron microscopy （SEm）, atomic force microscopy （AFm） and X-ray diffraction （XRD） techniques. microhardness measurements indicate a two-fold increase in hardness because of the produced nanos- lructure. Comparing to its coarse structure, the nanostructured Cu-A1-Ni shape memory alloy exhibited the enhanced mechanical properties including a ductility of 6.5% and a pronounced plateau in the stress-strain curve.

关键词： copper allosy shape memory effect melt spinning mechanical properties microstructural evolution

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Algorithm fusion to improve detection of lung cancer on chest radiographs

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International Journal of Intelligent Computing and Cybernetics 2012年第1期5卷 111-144页

作者： gergely Orbán gábor Horváth Department of measurement and Information Systems Budapest University of Technology and EconomicsBudapestHungary Intelligent Systems Research group Budapest University of Technology and EconomicsBudapestHungary

Purpose-The purpose of this paper is to show an efficient method for the detection of signs of early lung *** image processing algorithms are presented for different types of lesions,and a scheme is proposed for the combination of ***/methodology/approach-A computer aided detection(CAD)scheme was developed for detection of lung *** enables different lesion enhancer algorithms,sensitive to specific lesion subtypes,to be used *** image processing algorithms are presented for the detection of small nodules,large ones,and infiltrated *** outputs are merged,the false detection rate is reduced with four separated support vector machine(SVm)*** classifier input comes from a feature selection algorithm selecting from various textural and geometric features.A total of 761 images were used for testing,including the database of the Japanese Society of Radiological Technology(JSRT).Findings-The fusion of algorithms reduced false positives on average by 0.6 per image,while the sensitivity remained 80 per *** the JSRT database the system managed to find 60.2 per cent of lesions at an average of 2.0 false positives per *** effect of using different result evaluation criteria was tested and a difference as high as 4 percentage points in sensitivity was *** system was compared to other published ***/value-The study described in the paper proves the usefulness of lesion enhancement decomposition,while proposing a scheme for the fusion of ***,a new algorithm is introduced for the detection of infiltrated areas,possible signs of lung cancer,neglected by previous solutions.

关键词： Programming and algorithm theory Image processing Cancer Radiography medical diagnosis Lung nodule Infiltrated area Chest radiograph Lung cancer Early detection

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Intraoperative complication rates in cataract surgery performed by resident trainees and staff surgeons in a tertiary eyecare center in Hungary

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International Journal of Ophthalmology(English edition) 2022年第4期15卷 586-590页

作者： márton magyar gábor László Sándor László Ujváry Zoltán Zsolt Nagy gábor Tóth Department of Ophthalmology Semmelweis UniversityBudapest 1085Hungary

AIm: To compare the incidence of intraoperative complications during primary phacoemulsification(phaco) surgery between resident surgeons(residents) and staff surgeons(specialists) and to objectively determine the difficulty of stages in phaco surgery. mETHODS: This retrospective study included cases of phaco cataract surgery performed between January and December 2019. There were no exclusion criteria. For each patient, demographics, clinical history, case complexity, type of surgeon, and operative details were reviewed. Primary outcomes included intraoperative complication rates and the objective measure of difficulty in the steps of the surgery performed by residents and ***: A total of 3272 cases were included;7.4%(n=241) of cases were performed by residents. The overall complication rate was 5.4%(n=177). The intraoperative complication rate was significantly higher(Pmost frequent complications were posterior capsule tear(n=85, 2.6%), anterior capsule tear(n=50, 1.53%), zonular fiber loss(n=45, 1.38%), and dropped nucleus(n=15, 0.46%). Objectively, the most difficult steps during surgery were phaco in 66(60.0%), capsulorhexis in 21(19.1%), irrigation/aspiration in 13(11.8%), hydrodissection in 9(8.2%), and intraocular lens(IOL) implantation in 1(0.9%) case. CONCLUSION: Intraoperative complication rates are higher in residents than in specialists. The order of objective difficulty in phaco surgery steps is in line with the subjective findings of other surveys, revealing that the most challenging parts of phaco surgery are phaco and capsulorhexis.

关键词： cataract intraoperative complications resident phacoemulsification staff surgeon

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Photolysis studies on HCOOH and HCOO^- in presence of TiO_2 photocatalyst as suspension in aqueous medium

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Journal of Natural gas Chemistry 2009年第1期18卷 50-54页

作者： g. R. Dey k. N. R. Nair k. k. Pushpa Radiation and Photochemistry Division Bhabha Atomic Research Centre Trombay Mumbai 400 085 India

Photolysis studies on formic acid （HCOOH） and formate ion （HCOO-） in presence of TiO2, a photocatalyst, as suspension in water were carried out separately using 350 nm ultraviolet light. The products, such as H2, CO, CO2 and CH4, generated during the experiments were monitored with varying the ambient, light exposure time, and the concentration of HCOOH/HCOO-. The yields of CO in all these systems increased with light exposure time. In aerated systems, CO yields were higher in contrast to the deoxygenated （Ar-purged） systems under identical conditions. It is proposed apparently that the formation of CO is tak.ng place during the chemical reduction of in-situ generated CO2, a photo-mineralized product of HCOOH/HCOO-, but not through the direct photodecomposition or photodehydration （CO＋H2O） of solute molecules. The rates of CO formation during 1.3 m HCOOH photolysis in presence of TiO2 photocatalyst were evaluated to be 0.21 and 0.13 μl/min in aerated and Ar-purged systems, respectively. As compared with HCOOH systems, the CO yields are lower when 0.2 m HCOONa was exposed to light under identical conditions. The CO growth rates were evaluated to be 0.07 and 0.046 μl/min^-1 for aerated and deoxygenated HCOONa systems, respectively; moreover, the trend is quite similar to that of the HCOOH system. Under these conditions, the emission of H2 was also observed, and its yield was significantly higher in Ar-purged system as compared with the CO yields. However, in aerated system, the yields of these products were just opposite. The formation of low yield of methane was observed during photolysis of HCOOH/HCOO ions. In CO2 ambient, the yields of CO and H2 varied drastically with time.

关键词： formic acid formate ion photolysis TiO2

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