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Geographical distribution of red and green Noctiluca scintillans

Chinese Journal of Oceanology and Limnology 2011年第4期29卷 807-831页

作者： P. J. HARRISON k. furuya P. M. GLIBERT J. Xu H. B. LIU k. YIN J. H. W. LEE D. M. ANDERSON R. GOWEN A. R. AL-AZRI A. Y. T. HO Hong k.ng University of Science and Technology Clear Water Bay Hong Kong China Department of Aquatic Bioscience University of Tokyo Tokyo 113-8657 Japan University of Maryland Center for Environmental Science Horn Point Laboratory Cambridge MD 21613 USA School of Marine Sciences Sun Yat-Sen University Guangzhou 510275 China Department of Biology Woods Hole Oceanographic Institution Woods Hole MA 02543 USA Fisheries and Aquatic Ecosystems Branch Agri-Food and Biosciences Institute Belfast BT9 5PX UK Department of Marine Science and Fisheries Sultan Qaboos University Muscat 123 Sultanate of Oman Agriculture Fisheries and Conservation Department Hong Kong China

The dinoflagellate Noctiluca scintillans is one of the most important and abundant red tide organisms and it is distributed world-wide. It occurs in two forms. Red Noctiluca is heterotrophic and fills the role of one of the microzooplank.on grazers in the foodweb. In contrast, green Noctiluca contains a photosynthetic symbiont Pedinomonas noctilucae （a prasinophyte）, but it also feeds on other plank.on when the food supply is abundant. In this review, we document the global distribution of these two forms and include the first maps of their global distribution. Red Noctiluca occurs widely in the temperate to sub-tropical coastal regions of the world. It occurs over a wide temperature range of about 10℃ to 25℃ and at higher salinities （generally not in estuaries）. It is particularly abundant in high productivity areas such as upwelling or eutrophic areas where diatoms dominate since they are its preferred food source. Green Noctiluca is much more restricted to a temperature range of 25℃-30℃ and mainly occurs in tropical waters of Southeast Asia, Bay of Bengal （east coast of India）, in the eastern, western and northern Arabian Sea, the Red Sea, and recently it has become very abundant in the Gulf of Oman. Red and green Noctiluca do overlap in their distribution in the eastern, northern and western Arabian Sea with a seasonal shift from green Noctiluca in the cooler winter convective mixing, higher productivity season, to red Noctiluca in the more oligotrophic warmer summer season.

关键词： Noctiluca global distribution distribution map green Noctiluca dinoflagellate

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和1995年神户地震有关的同震泉水日流量变化

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世界地震译丛 2001年第3期32卷 81-84页

作者： T. Sato R. Sak.i k. furuya T. k.dama 杨国栋王建荣中国地震局兰州地震研究所

1995年神户地震以后,很多泉的流量迅速增加,这可能是由渗透率增加引起的。淡路岛距离神户不远,从1995年到1998年,岛上9个泉的流量变化显示出,增加的流量在两年之内逐渐呈指数衰减。我们用一个很简单的扩散模型来估算蓄水层增强了的水压... 详细信息

1995年神户地震以后,很多泉的流量迅速增加,这可能是由渗透率增加引起的。淡路岛距离神户不远,从1995年到1998年,岛上9个泉的流量变化显示出,增加的流量在两年之内逐渐呈指数衰减。我们用一个很简单的扩散模型来估算蓄水层增强了的水压扩散率,其值为130～2300 cm^2/s。根据分析,我们推测本次地震使渗透率和泉水流量增加了约7倍。

关键词：神户地震水压日流量同震流量变化泉水流量扩散率

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Preoperative albumin-bilirubin score and liver resection percentage determine postoperative liver regeneration after partial hepatectomy

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World Journal of Gastroenterology 2024年第14期30卷 2006-2017页

作者： k.zuhiro Tak.hashi Masahik. Gosho Yoshihiro Miyazak. Hiromitsu Nak.hashi Osamu Shimomura k.nji furuya Manami Doi Yohei Owada k.ichi Ogawa Yusuk. Ohara Yoshimasa Ak.shi Tsuyoshi Enomoto Shinji Hashimoto Tatsuya Oda Department of Gastrointestinal and Hepatobiliary-Pancreatic Surgery University of TsukubaTsukuba 3058-575IbarakiJapan Department of Biostatistics University of TsukubaTsukuba 3058-575IbarakiJapan

BACk.ROUND The success of liver resection relies on the ability of the remnant liver to *** of the k.owledge regarding the pathophysiological basis of liver regeneration comes from rodent studies,and data on humans are ***,there is limited k.owledge about the preoperative factors that influence postoperative *** To quantify postoperative remnant liver volume by the latest volumetric software and investigate perioperative factors that affect posthepatectomy liver *** A total of 268 patients who received partial hepatectomy were *** were grouped into right hepatectomy/trisegmentectomy(RH/Tri),left hepa-tectomy(LH),segmentectomy(Seg),and subsegmentectomy/nonanatomical hepatectomy(Sub/Non)*** regeneration index(RI)and late rege-neration rate were defined as(postoperative liver volume)/[total functional liver volume(TFLV)]×100 and(RI at 6-months-RI at 3-months)/RI at 6-months,*** lower 25th percentile of RI and the higher 25th percentile of late regeneration rate in each group were defined as“low regeneration”and“delayed regeneration”.“Restoration to the original size”was defined as regeneration of the liver volume by more than 90%of the TFLV at 12 months *** The numbers of patients in the RH/Tri,LH,Seg,and Sub/Non groups were 41,53,99 and 75,*** RI plateaued at 3 months in the LH,Seg,and Sub/Non groups,whereas the RI increased until 12 months in the RH/Tri *** to our multivariate analysis,the preoperative albumin-bilirubin(ALBI)score was an independent factor for low regeneration at 3 months[odds ratio(OR)95%CI=2.80(1.17-6.69),P=0.02;per 1.0 up]and 12 months[OR=2.27(1.01-5.09),P=0.04;per 1.0 up].Multivariate analysis revealed that only liver resection percentage[OR=1.03(1.00-1.05),P=0.04]was associated with delayed ***,multivariate analysis demonstrated that the preoperative ALBI score[OR=2.63(1.00-1.05),P=0.02;per 1.

关键词： Liver regeneration Albumin-bilirubin score Liver resection percentage Partial hepatectomy Human Regeneration index

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High-grade pancreatic intraepithelial neoplasia diagnosed based on changes in magnetic resonance cholangiopancreatography findings:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1487-1496页

作者： Nao furuya Atsushi Yamaguchi Naohiro k.to Syuhei Sugata Tak.ro Hamada Tak.shi Mizumoto Yuzuru Tamaru Ryusak. k.sunok. Toshio k.wai Hirotak. k.uno k.zuya k.raok. Yoshiyuk. Shibata Sho Tazuma Tak.shi Sudo Hiroshi k.hno Shiro Ok. Department of Gastroenterology National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan Department of Gastroenterology Hiroshima University HospitalHiroshima 734-8551HiroshimaJapan Department of Pathology National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan Department of Surgery National Hospital Organization Kure Medical Center and Chugoku Cancer CenterKure 737-0023HiroshimaJapan

BACk.ROUND High-grade pancreatic intraepithelial neoplasia(PanIN)exhibits no mass and is not detected by any examination ***,it can be diagnosed by pancreatic juice cytology from indirect *** previous cases were diagnosed based on findings of a focal stricture of the main pancreatic duct(MPD)and caudal MPD dilatation and subsequent pancreatic juice cytology using endoscopic retrograde cholangiopancreatography(ERCP).We experienced a case of high-grade PanIN with an unclear MPD over a 20-mm range,but without caudal MPD dilatation on magnetic resonance cholangiopancreatography(MRCP).CASE SUMMARY A 60-year-old female patient underwent computed tomography for a follow-up of uterine cancer post-excision,which revealed pancreatic *** revealed an unclear MPD of the pancreatic body at a 20-mm length without caudal MPD ***,course observation was *** 24 mo,MRCP revealed an increased caudal MPD caliber and a larger pancreatic *** performed ERCP and detected atypical cells suspected of adenocarcinoma by serial pancreatic juice aspiration cytology *** performed a distal pancreatectomy and obtained a histopathological diagnosis of high-grade *** parenchyma invasion was not observed,and curative resection was *** High-grade Pan-IN may cause MPD narrowing in a long range without caudal MPD dilatation.

关键词： Pancreatic cancer Pancreatic intraepithelial neoplasm High-grade pancreatic intraepithelial neoplasm Magnetic resonance cholangiopancreatography Carcinoma in situ Case report

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Symptomatic COVID-19 in University Students: A School-Wide Web-Based Questionnaire Survey during the Omicron Variant Outbreak

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Advances in Infectious Diseases 2024年第1期14卷 133-146页

作者： Mai k.tahara Hisami Sameshima Rie Tanuma k.mi Setoyama Yuk. Yamaguchi Ak.yo k.machi Satok. Nak.mura Mayuk. Sak.ma Yoichi k.waik. Tamotsu furuya Shinji Ijichi Health Service Center Kagoshima University Kagoshima Japan Center for Management of Information Technologies Kagoshima University Kagoshima Japan

Aim: To detect risk.and preventive factors associated with the Omicron variant infection in university students, a combination of a web-based survey and multivariate logistic regression analysis was introduced as the front-line initiatives by the school health practitioners. Design: Questionnaire survey. Methods: The school-wide web-based questionnaire survey was conducted among our university students as a part of the annual health check.up in April, 2023. The positive outcome was confined to the first symptomatic COVID-19 onset during the Omicron variant outbreak. Results: In this self-administered survey, risk.or protective associations were merely estimated statistically in university students (n = 5406). In measured factors, k.raok. and club/group activities could maintain the statistical significance in adjusted odds ratios (ORs) as relative risk.factors, and science course, measles/ rubella (MR) vaccination, and COVID-19 vaccination remained as relative protective factors in adjusted OR analyses. Club/group activities with member gathering and k.raok. sing-along sessions in university students may frequently have WHO’s three Cs. These risk.factors are still important topics for the infection control of COVID-19 in university students. Together with some recent reports from other researchers, the significant protective role of MR vaccine in our survey warrants further clinical investigation. If the break.hrough infection continuously constitutes the majority of infection, real data in test-negative case-control or web-based questionnaire design continue to be important for statistical analysis to determine the minimal requirement of our strategies which may be equivalent to or replace COVID-19 vaccines.

关键词： Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Coronavirus Disease 2019 (COVID-19) Omicron Variant Risk.Behaviors Protective Factors

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Human β-defensin-3 induction in H pylori-infected gastric mucosal tissues

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World Journal of Gastroenterology 2006年第36期12卷 5793-5797页

作者： k.k.wauchi A Yagihashi N Tsuji N Uehara D furuya D k.bayashi N Watanabe Department of Clinical Laboratory Medicine Sapporo Medical University School of Medicine Sapporo Japan

AIM: To examine human β-defensin-3 (hBD-3) expression in inflamed gastric mucosal tissues or Mk.45 gastric cancer cells with or without H pylori infection for better understanding the innate immune response to H pylori. METHODS: We used reverse transcription-polymerase chain reactions and immunohistochemistry to examine hBD-3 expression in inflamed gastric mucosal tissues or Mk.45 gastric cancer cells with or without H pylori. Effects of hBD-3 against H pylori were also evaluated. RESULTS: The mean mRNA expression of hBD-3 in H pylori -positive specimens was significantly higher than that in H pylori-negative specimens (P = 0.0002, Mann-Whitney). In addition, unlik. uninfected samples, 8 of 15 (53.33%) infected mucosal samples expressed hBD-3 protein. H pylori dose-dependently induced mRNA expression of hBD-3 in Mk.45 cells, an effect inhibited by adding anti-toll-lik. receptor (TLR)-4 antibody. HBD-3 protein completely inhibited H pylori growth. CONCLUSION: Our results suggest that lik. hBD-2, hBD-3 may be involved in the pathophysiology of H pylori-induced gastritis.

关键词： Human β-defensin-2 Human β-defensin-3 Hpylori Gastric mucosa

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A Rice Phytochrome A in Arabidopsis： The Role of the N-terminus under red and far-red light

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Molecular Plant 2008年第1期1卷 84-102页

作者： Julia k.eissl Tomok. Shinomura Masak. furuya Cordelia Bolle Ludwig-Maximilians-Universitat Munchen Bereich Botanik Menzinger Str. 67 80638 Munchen Germany Hitachi Advanced Research Laboratory Hatoyama Saitama 350-0395 Japan

The phytochrome （phy）A and phyB photoreceptors mediate three photobiological response modes in plants; whereas phyA can mediate the very-low-fluence response （VLFR）, the high-irradiance response （HIR） and, to some extent, the low fluence response （LFR）, phyB and other type U phytochromes only mediate the LFR. To investigate to what level a rice phyA can complement for Arabidopsis phyA or phyB function and to evaluate the role of the serine residues in the first 20 amino acids of the N-terminus of phyA, we examined VLFR, LFR, and HIR responses in phyB and phyAphyB mutant plants transformed with rice PHYA cDNA or a mutant rice PHYA cDNA in which the first 10 serine residues were mutated to alanines （phyA SA）. Utilizing mutants without endogenous phyB allowed the evaluation of red-light-derived responses sensed by the rice phyA. In summary, the WT rice phyA could complement VLFR and LFR responses such as inhibition of hypocotyl elongation under pulses of FR or continuous R light, induction of flowering and leaf expansion, whereas the phyA SA was more specific for HIR responses （e.g. inhibition of hypocotyl elongation and anthocyanin accumulation under continuous far-red light）. As the N-terminal serines can no longer be phosphorylated in the phyA SA mutant, this suggests a role for phosphorylation discriminating between the different phyA-dependent responses. The efficacy of the rice phyA expressed in Arabidopsis was dependent upon the developmental age of the plants analyzed and on the physiological response, suggesting a stage-dependent downstream modulation of phytochrome signaling.

关键词： phytochrome (phy) high-irradiance response (HIR) very-low-fluence response (VLFR)

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Dualistic role of platelets in living donor liver transplantation: Are they harmful?

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World Journal of Gastroenterology 2022年第9期28卷 897-908页

作者： Chen Liang k.zuhiro Tak.hashi k.nji furuya Nobuhiro Ohk.hchi Tatsuya Oda Gastrointestinal and Hepatobiliary-Pancreatic Surgery University of TsukubaTsukuba 3058575IbarakiJapan

Platelets are anucleate fragments mainly involved in hemostasis and thrombosis,and there is emerging evidence that platelets have other nonhemostatic potentials in inflammation,angiogenesis,regeneration and ischemia/reperfusion injury(I/R injury),which are involved in the physiological and pathological processes during living donor liver transplantation(LDLT).LDLT is sometimes associated with impaired regeneration and severe I/R injury,leading to postoperative complications and decreased patient *** studies have suggested that perioperative thrombocytopenia is associated with poor graft regeneration and postoperative morbidity in the short and long term after *** it is not fully understood whether thrombocytopenia is the cause or result,increasing platelet counts are frequently suggested to improve posttransplant outcomes in clinical *** on rodent experiments,previous studies have identified that platelets stimulate liver regeneration after partial ***,the role of platelets in LDLT is controversial,as platelets are supposed to aggravate I/R injury in the ***,a rat model of partial liver transplantation(LT)was used to demonstrate that thrombopoietin-induced thrombocytosis prior to surgery accelerated graft regeneration and improved the survival rate after *** was clarified that platelet-derived liver regeneration outweighed the associated risk.of I/R injury after partial *** strategies to increase perioperative platelet counts,such as thrombopoietin,thrombopoietin receptor agonist and platelet transfusion,may improve graft regeneration and survival after LDLT.

关键词： Platelet Liver transplantation Regeneration Ischemia/reperfusion injury k.pffer cell Oxidative stress

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