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在结核病人完成治疗疗程以前医生决定停止治疗的相关因素

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国际结核病与肺部疾病杂志 2008年第4期3卷 169-174页

作者： C-Y.Chiang D.A.Enarson k-t.luh 张天豪何广学 International Union Against tuberculosis and Lung Disease ParisFrance National tuberculosis Association Taipei

目的:调查肺结核病的诊断和在结核病人完成疗程以前医生决定停止治疗的相关因素。设计:调查台湾地区台北市所有居民医疗档案中,在2003年已经接受治疗的肺结核病人。结果:1 126例肺结核病人中,512例(45.5%)仅根据胸部X线检查结果立即开... 详细信息

目的:调查肺结核病的诊断和在结核病人完成疗程以前医生决定停止治疗的相关因素。设计:调查台湾地区台北市所有居民医疗档案中,在2003年已经接受治疗的肺结核病人。结果:1 126例肺结核病人中,512例(45.5%)仅根据胸部X线检查结果立即开始治疗,214例(19.0%)基于痰涂片检查发现抗酸杆菌阳性进行治疗,261例(23.2%)基于其他检查结果,还有139例(12.3%)根据细菌培养阳性的结果。在1126例肺结核患者中,156例(13.9%)被临床医生改变了结核病的诊断。多因素分析显示,仅依靠X光胸片或其他方法、女性病人、中断治疗2个月的病人、在其他卫生机构(转诊)继续治疗的病人以及肺癌病人与其他组相比有更大的改变诊断可能性。结论:有一部分的病人基于单独的胸部X线检查结果给予抗结核治疗,其中相当比例在完成结核病治疗全疗程前被医生劝告停止治疗,调查表明对台湾结核病控制项目需要尽快引起关注。

关键词：结核病诊断治疗台湾

台北结核病患者治疗转归:与中断治疗2个月和死亡相关的因素

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国际结核病与肺部疾病杂志 2010年第2期5卷 105-111页

作者： C-Y.Chiang J-J.Lee M-C.Yu k-t.luh 徐汉成(译) 王雪静(校) International Union Against tuberculosis and Lung Disease Paris France Division of Chest Medicine Department of Internal Medicine Buddhist tzu Chi General Hospital tzu Chi University Hualien taiwan tuberculosis Association Taipei 不详

背景:2003年在台湾台北市所有登记治疗的肺结核患者目的:调查研究与中断治疗至少2个月和死亡相关的危险因素方法:由就诊病历来确定肺结核患者的治疗转归。结果:在登记的1 127例肺结核患者中,824例(73.1%)治疗成功,189例(16.8%)死亡,65例... 详细信息

背景:2003年在台湾台北市所有登记治疗的肺结核患者目的:调查研究与中断治疗至少2个月和死亡相关的危险因素方法:由就诊病历来确定肺结核患者的治疗转归。结果:在登记的1 127例肺结核患者中,824例(73.1%)治疗成功,189例(16.8%)死亡,65例(5.8%)中断治疗,17例(1.5%)已治疗15个月仍在继续治疗,32例(2.8%)治疗失败。与治疗中断显著相关的唯一因素是在开始抗结核治疗后去了其他医疗机构。结核病患者的标化死亡比率为8.7(95%可信区间为7.5～10.0)。与其他患者相比,死亡患者中与其死亡显著相关的因素有:年龄(调整风险比为1.06,95%可信区间为1.05～1.08)、未做痰培养或结果未知(调整风险比为2.07,95%可信区间为1.47～2.92)、合并呼吸系统疾病(调整风险比为1.68,95%可信区间为1.24～2.27),合并感染性疾病(调整风险比为2.80,95%可信区间为2.07～3.78),合并肾脏疾病(调整风险比为2.58,95%可信区间为1.82～3.66)或合并癌症(调整风险比为3.31,95%可信区间为2.35～4.65)。结论:到其他医疗机构就诊是与中断治疗至少2个月相关的因素。高死亡比例是由于年龄大和合并症。

关键词：死亡丢失、结核、转归

EVOLUtION AND INtERACtION OFδ-WAVES IN tHE ZERO-PRESSURE GAS DYNAMICS SYStEM

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Acta Mathematica Scientia 2024年第5期44卷 1801-1836页

作者： Abhishek DAS k.t.JOSEPH Centre for Data Science Institute of Technical Education and Research(ITER)Siksha‘O’Anusandhan(Deemed to be University)BhubaneswarOdisha751030India Centre for Applicable Mathematics Tata Institute of Fundamental ResearchSharada NagarBangalore560065KarnatakaIndia

Evolution and interaction of plane waves of the multidimensional zero-pressure gas dynamics system leads to the study of the corresponding one dimensional *** this paper,we study the initial value problem for one dimensional zero-pressure gas dynamics *** the first equation is the Burgers equation and the second one is the continuity *** consider the solution with initial data in the space of bounded Borel *** we prove a general existence result in the algebra of generalized functions of *** we study in detail special solutions withδ-measures as initial *** study interaction of waves originating from initial data concentrated on two point sources and interaction with classical shock/rarefaction *** gives an understanding of plane-wave interactions in the multidimensional *** use the vanishing viscosity method in our analysis as this gives the physical solution.

关键词： zero-pressure gas dynamics delta-waves interaction of waves

Evaluation of slope stability through rock mass classification and kinematic analysis of some major slopes along NH-1A from Ramban to Banihal, North Western Himalayas

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第1期16卷 167-182页

作者： Amit Jaiswal A.k.Verma t.N.Singh Department of Civil and Environmental Engineering Indian Institute of Technology PatnaPatna801106India

the network of Himalayan roadways and highways connects some remote regions of valleys or hill slopes,which is vital for India’s socio-economic *** to natural and artificial factors,frequency of slope instabilities along the networks has been increasing over last few *** of stability of natural and artificial slopes due to construction of these connecting road networks is significant in safely executing these roads throughout the *** rock mass classification methods are generally used to assess the strength and deformability of rock *** study assesses slope stability along the NH-1A of Ramban district of North Western *** structurally and non-structurally controlled rock mass classification systems have been applied to assess the stability conditions of 14 *** evaluating the stability of these slopes,kinematic analysis was performed along with geological strength index(GSI),rock mass rating(RMR),continuous slope mass rating(CoSMR),slope mass rating(SMR),and Q-slope in the present *** SMR gives three slopes as completely unstable while CoSMR suggests four slopes as completely *** stability of all slopes was also analyzed using a design chart under dynamic and static conditions by slope stability rating(SSR)for the factor of safety(FoS)of 1.2 and 1 respectively.Q-slope with probability of failure(PoF)1%gives two slopes as stable *** slope angle has been determined based on the Q-slope safe angle equation and SSR design chart based on the *** value ranges given by different empirical classifications were RMR(37-74),GSI(27.3-58.5),SMR(11-59),and CoSMR(3.39-74.56).Good relationship was found among RMR&SSR and RMR&GSI with correlation coefficient(R 2)value of 0.815 and 0.6866,***,a comparative stability of all these slopes based on the above classification has been performed to identify the most critical slope along this road.

关键词： Rock mass classification kinematic analysis Slope stability Himalayan road Static and dynamic conditions

Near resonance vibration isolation on a levered-dual response(LEDAR)Coulomb-damped system by differential preloads/offsets in linear springs

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Applied Mathematics and Mechanics(English Edition) 2024年第6期45卷 1033-1050页

作者： t.I.tOLUWALOJU C.k.tHEIN D.HALIM Department of Mechanical Materials and Manufacturing EngineeringUniversity of Nottingham Ningbo ChinaNingbo 315100Zhejiang ProvinceChina Nottingham Ningbo China Beacons of Excellence Research and Innovation Institute University of Nottingham Ningbo ChinaNingbo 315048Zhejiang ProvinceChina

the levered-dual response(LEDAR)Coulomb-damped system attains near resonant vibration isolation by differential preloads/offsets in linear *** takes the advantages of both the preloads/offsets in linear springs and the guiderail friction for realizing different levels of vibration *** isolation capacities are investigated on the strategies with both the horizontal and vertical guiderails,with the horizontal rail only,and without *** compressive preloads generally result in the consumption of most of the initial excitation energy so as to overcome the potential *** isolation onsets at the frequency ratio of 1∓0.095 on the left-hand side(LHS)and the right-hand side(RHS)of the lever are relative to the load plate *** observed near resonant isolation thus makes the LEDAR system a candidate for the isolation of the mechanical systems about resonance while opening a path for simultaneous harvesterisolation functions and passive functions at extreme frequencies.

关键词： lever ratio Coulomb damping preload tension/compression isolation band/depth offset potential

Radiative heat transfer analysis of a concave porous fin under the local thermal non-equilibrium condition:application of the clique polynomial method and physics-informed neural networks

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Applied Mathematics and Mechanics(English Edition) 2024年第9期45卷 1613-1632页

作者： k.CHANDAN k.kARtHIk k.V.NAGARAJA B.C.PRASANNAkUMARA R.S.VARUN kUMAR t.MUHAMMAD Amrita School of Artificial Intelligence Amrita Vishwa VidyapeethamBengaluru 560035KarnatakaIndia Department of Studies in Mathematics Davangere UniversityDavangere 577002KarnatakaIndia Computational Science Lab Amrita School of EngineeringAmrita Vishwa VidyapeethamBengaluru 560035KarnatakaIndia Department of Pure and Applied Mathematics School of Mathematical SciencesSunway UniversityPetaling Jaya 47500Malaysia Department of Mathematics College of ScienceKing Khalid UniversityAbha 61413Saudi Arabia

the heat transfer through a concave permeable fin is analyzed by the local thermal non-equilibrium(LtNE)*** governing dimensional temperature equations for the solid and fluid phases of the porous extended surface are modeled,and then are nondimensionalized by suitable dimensionless ***,the obtained nondimensional equations are solved by the clique polynomial method(CPM).the effects of several dimensionless parameters on the fin's thermal profiles are shown by graphical ***,the current study implements deep neural structures to solve physics-governed coupled equations,and the best-suited hyperparameters are attained by comparison with various network *** results of the CPM and physicsinformed neural network(PINN)exhibit good agreement,signifying that both methods effectively solve the thermal modeling problem.

关键词： heat transfer fin porous fin local thermal non-equilibrium(LtNE)model physics-informed neural network(PINN)

Product family modeling technology for customized cosmetic packaging design based on basic-element theory

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Journal of dermatologic science and cosmetic technology

Journal of dermatologic science and cosmetic technology 2024年第1期1卷 2-12页

作者： tao Chen Ding-Bang luh Jinguang Wang College of Arts and Design Shandong University of Science and TechnologyQingdao 266590China School of Art and Design Guangdong University of TechnologyGuangzhou 510062China

Background:As the market demands change,SMEs(small and medium-sized enterprises)have long faced many design issues,including high costs,lengthy cycles,and insufficient *** issues are especially noticeable in the domain of cosmetic packaging ***:to explore innovative product family modeling methods and configuration design processes to improve the efficiency of enterprise cosmetic packaging design and develop the design for mass ***:to accomplish this objective,the basic-element theory has been introduced and applied to the design and development system of the product ***:By examining the mapping relationships between the demand domain,functional domain,technology domain,and structure domain,four interrelated models have been developed,including the demand model,functional model,technology model,and structure ***,these models form the mechanism and methodology of product family modeling,specifically for cosmetic packaging *** an analysis of a case study on men’s cosmetic packaging design,the feasibility of the proposed product family modeling technology has been demonstrated in terms of customized cosmetic packaging design,and the design efficiency has been ***:the product family modeling technology employs a formalized element as a module configuration design language,permeating throughout the entire development cycle of cosmetic packaging design,thus facilitating a structured and modularized configuration design process for the product family *** application of the basic-element principle in product family modeling technology contributes to the enrichment of the research field surrounding cosmetic packaging product family configuration design,while also providing valuable methods and references for enterprises aiming to elevate the efficiency of cosmetic packaging design for the mass customization product model.

关键词： Packaging design Cosmetic packaging Product family modeling technology Basic-element theory Design for mass customization

SARS-CoV-2 and innate immunity:the good,the bad,and the"goldilocks"

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Cellular & Molecular Immunology 2024年第2期21卷 171-183页

作者： Benjamin L.Sievers Mark t.k.Cheng kata Csiba Bo Meng Ravindra k.Gupta Department of Medicine University of CambridgeCambridgeUK Cambridge Institute of therapeutic Immunology&Infectious Disease(CItID) Department of MedicineUniversity of CambridgeCambridgeUk

An ancient conflict between hosts and pathogens has driven the innate and adaptive arms of *** about this interplay can not only help us identify biological mechanisms but also reveal pathogen vulnerabilities that can be leveraged *** humoral response to SARS-CoV-2 infection has been the focus of intense research,and the role of the innate immune system has received significantly less ***,we review current knowledge of the innate immune response to SARS-CoV-2 infection and the various means SARS-CoV-2 employs to evade innate defense *** also consider the role of innate immunity in SARS-CoV-2 vaccines and in the phenomenon of long COVID.

关键词： SARS-CoV-2 Innate immune response Interferon Cytokines Inflammation Antiviral targets

Supposition of graphene stacks to estimate the contact resistance and conductivity of nanocomposites

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 663-676页

作者： Y.ZARE M.t.MUNIR G.J.WENG k.Y.RHEE Biomaterials and tissue Engineering Research Group Department of Interdisciplinary TechnologiesBreast Cancer Research CenterMotamed Cancer InstituteTehran ***Iran College of Engineering and technology American University of the Middle EastEgaila 54200Kuwait Department of Mechanical and Aerospace Engineering Rutgers UniversityNew BrunswickNJ 08903U.S.A. Department of Mechanical Engineering(Bk21 Four) College of EngineeringKyung Hee UniversityYongin 446701Republic of Korea

In this study,the effects of stacked nanosheets and the surrounding interphase zone on the resistance of the contact region between nanosheets and the tunneling conductivity of samples are evaluated with developed equations superior to those previously *** contact resistance and nanocomposite conductivity are modeled by several influencing factors,including stack properties,interphase depth,tunneling size,and contact *** developed model's accuracy is verified through numerous experimental *** further validate the models and establish correlations between parameters,the effects of all the variables on contact resistance and nanocomposite conductivity are ***,the contact resistance is primarily dependent on the polymer tunnel resistivity,contact area,and tunneling *** dimensions of the graphene nanosheets significantly influence the conductivity,which ranges from 0 S/m to90 S/*** increased number of nanosheets in stacks and a larger gap between them enhance the nanocomposite's ***,the thicker interphase and smaller tunneling size can lead to higher sample conductivity due to their optimistic effects on the percolation threshold and network efficacy.

关键词： graphene polymer composite stacked nanosheet tunneling conductivity contact resistance interphase