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An unusual case of symmetric quadruple limb fractures

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中华创伤杂志:英文版 2023年第5期26卷 303-307页

作者： Vivek vijayakumar Hemant Bansal kamran Farooque Vijay Sharma Department of Orthopaedics Jai Prakash Narayan Apex Trauma CentreAll India Institute of Medical SciencesNew DelhiIndia

A 19-year-old man had an accidental fall from the 2nd floor and sustained multiple *** radiological evaluation,the patient had symmetrical quadruple limb involvement with bilateral humerus shaft,bilateral olecranon,bilateral femur shaft,and bilateral patella *** patient was actively managed using damage control orthopaedics,and a sequence of skeletal fixation was planned based on the hemodynamic stability and periodical serum lactate *** quadruple limb fractures are very rare,which could be associated with higher mortality.A meticulous clinical evaluation,periodical blood parameter assessment and strict adherence to the principles of damage control orthopaedics can be conducive to prevent life-endangering complications.

关键词： Femoral fractures Bilateral Humerus fractures Quadruple limbs

Prevalance and pathology of gastric tumours in Indian oil sardine(Sardinella longiceps)from Parangipettai coastal waters,southeast coast of India

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Journal of Coastal Life Medicine 2015年第8期 592-595页

作者： Vijayapoopathi Singaravel Ayyaru Gopalakrishnan Ramalingam vijayakumar kuzhanthaivel Raja Centre of Advanced Study in Marine Biology Faculty of Marine SciencesAnnamalai UniversityParangipettai-608502TamilnaduIndia

Objective:To carry out the survey of prevalence of gastric tumour in Sardinella longiceps of Parangipettai coastal waters,south east coast of India for a period of one ***:Fish samples were directly collected from fishermen and also from auction *** prevalence of gastric tumour,gross pathology,radiography,histopathology,morphometric and meristic characters were ***:A total of 31 stomach tumour infected individuals were collected during the study *** gross morphology showed distended abdomen and the radiograph exhibited enlargement of *** of the infected fish exhibited reddish multilobed tumourous growth on the ***,the tumour lesions were characterized by the differential rate of glandular epitheloid and mesenchymal cells,polymorphic and hyperchromatic nuclei and mitotic *** evidence of local invasion and distinct metastases were observed in these ***:The tumours were diagnosed as gastric adenoma,myofibroblastoma,lipoma and *** them myofibroblastoma is highly prevalent.

关键词： Indian oil sardine Gastric tumours Radiography Histopathology

Mechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infection

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World Journal of Virology 2015年第1期4卷 17-24页

作者： Esaki M Shankar vijayakumar Velu Adeeba kamarulzaman Marie Larsson Tropical Infectious Disease Research and Education Center Department of Medical MicrobiologyFaculty of MedicineUniversity of Malaya Department of Microbiology and Immunology Emory Vaccine CenterYerkes National Primate Research Center Center of Excellence for Research in AIDS University of Malaya Division of Molecular Virology Department of Clinical and Experimental MedicineLink?ping University

Immunosenescence is marked by accelerated degradation of host immune responses leading to the onset of opportunistic infections, where senescent T cells show remarkably higher ontogenic defects as compared to healthy T cells. The mechanistic association between T-cell immunosenescence and human immunodeficiency virus(HIV) disease progression, and functional T-cell responses in HIV-tuberculosis(HIV-TB) co-infection remains to be elaborately discussed. Here, we discussed the association of immunosenescence and chronic immune activation in HIV-TB co-infection and reviewed the role played by mediators of immune deterioration in HIV-TB coinfection necessitating the importance of designing therapeutic strategies against HIV disease progression and pathogenesis.

关键词： Cluster of differentiation 38 Human immunodeficiency virus-tuberculosis co-infection Immunosenescence

Four types of neoplasms in Asian sea bass(Lates calcarifer)

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Journal of Coastal Life Medicine 2015年第6期 438-440页

作者： Ramalingam vijayakumar kuzhanthaivel Raja Vijayapoopathi Singaravel Ayyaru Gopalakrishnan Centre of Advanced Study in Marine Biology Faculty of Marine ScienceAnnamalai UniversityParangipettai Tamil NaduIndia

Objective:To describe and observe four types of neoplasms on different parts(external and internal organs)of an Asian sea bass(Lates calcarifer).Methods:The sample was collected from local fish landing center(south east coast of India).Histopathology of normal and tumour tissues were ***:A total of 83 tumour masses(neoplasm)were recorded on the fish skin,also the neoplasms were recorded in internal organs of fish such as liver,stomach and ***:Aetiology of such neoplasm’s are unknown,further more researches need to confirm the causative agent for this type of neoplasm.

关键词： Neoplasm Lates calcarifer Skin Liver Stomach Ovary

Challenges in animal modelling of mesenchymal stromal cell therapy for inflammatory bowel disease

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World Journal of Gastroenterology 2015年第16期21卷 4779-4787页

作者： Raghavan Chinnadurai Spencer Ng vijayakumar Velu Jacques Galipeau Department of Hematology and Oncology Winship Cancer InstituteEmory University Emory Vaccine Center Yerkes National Primate Research CenterEmory University Department of Pediatrics Emory University

Utilization of mesenchymal stromal cells(MSCs) for the treatment of Crohn's disease and ulcerative colitis is of translational *** of MSC therapy has been well demonstrated in early phase clinical trials but efficacy in randomized clinical trials needs to be *** MSC mechanisms of action to reduce gut injury and inflammation is necessary to improve current ongoing and future clinical ***, two major hurdles impede the direct translation of data derived from animal experiments to the clinical situation:(1) limitations of the currently available animal models of colitis that reflect human inflammatory bowel diseases(IBD).The etiology and progression of human IBD are multifactorial and hence a challenge to mimic in animal models; and(2) Species specific differences in the functionality of MSCs derived from mice versus *** derived from mice and humans are not identical in their mechanisms of action in suppressing ***, preclinical animal studies with murine derived MSCs cannot be considered as an exact replica of human MSC based clinical *** the present review, we discuss the therapeutic properties of MSCs in preclinical and clinical studies of *** also discuss the challenges and approaches of using appropriate animal models of colitis, not only to study putative MSC therapeutic efficacy and their mechanisms of action, but also the suitability of translating findings derived from such studies to the clinic.

关键词： Mesenchymal stromal cells Inflammatorybowel disease colitis Animal model Crohn's disaese

CLEANROOM AIR FILTERS:DESIGN AND TESTING

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CLEANROOM AIR FILTERS:DESIGN AND TESTING

Isolation and identification of marine fish tumour(odontoma)associated bacteria

第二届中国国际过滤材料研讨会

作者： R.vijayakumar Ph.D. Air Techniques International Air Techniques International

＜正＞ Air filters for particle removal are the primary means for providing clean air for a host of activities requiringclean environments or cleanrooms. Although cleanrooms are commonly associated with the high tech microelectron-ics or the regulated pharmaceutical industries, a growing number of other industries, such as spray painting andpackaging food, are requiring cleanrooms. Filters designed and tested to satisfy the needs of these clean environ-ments are loosely termed cleanroom filters. Unlike filters used for general HVAC applications, cleanroom filters focus less on capacity and more on pene-

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Journal of Coastal Life Medicine 2015年第9期 682-685页

作者： Ramalingam vijayakumar kuzhanthaivel Raja Vijayapoopathi Singaravel Ayyaru Gopalakrishnan Centre of Advanced Study in Marine Biology Faculty of Marine SciencesAnnamalai UniversityParangipettaiTamil NaduIndia

Objective:To identify fish tumour associated ***:The marine fish Sphyraena jello with odontoma was collected from in Tamil Nadu(Southeast India),and tumour associated bacteria were *** the isolated bacteria were identified based on molecular ***:A total of 4 different bacterial species were isolated from tumour *** bacterial species were Bacillus sp.,Pontibacter sp.,Burkholderia *** Macrococcus sp.,and the sequences were submitted in DNA Data Bank of Japan with accession numbers of AB859240,AB859241,AB859242 and AB859243 ***:Four different bacterial species were isolated from Sphyraena jello,but the role of bacteria within tumour needs to be further investigated.

关键词： Sphyraena jello Odontoma Bacillus sp Pontibacter sp Burkholderia sp Macrococcus sp

Synthesis and characterization of ZnS-based quantum dots to trace low concentration of ammonia

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Journal of Semiconductors 2021年第12期42卷 72-79页

作者： Uma Devi Godavarti P.Nagaraju vijayakumar Yelsani Yamuna Pushukuri P.S.Reddy Madhavaprasad Dasari Nanosensor Research Laboratory Department of PhysicsCMR Technical CampusMedchalHyderabadTelangana 501401India Department of Physics Anurag UniversityHyderabadTelangana 500088India Department of Physics Mallareddy Engineering College(Autonomous)DulapallyHyderabad 500100India Department of Applied Sciences NIT GoaGoa 403401India Department of Physics Gitam UniversityVisakhapatnam(A.P.)530045India

In the present work,a solution-based co-precipitation method has been adopted to synthesize pure and cobalt-doped ZnS quantum dots and characterized by XRD,SEM,TEM with EDX,FTIR and gas sensing *** analysis has shown a single phase of ZnS quantum dots having a zinc blend *** and XRD line broadening indicated that the average crystallite size in the sample is in the range of 2 to 5 *** micrographs show spherical-shaped quantum *** studies show that cobalt has been successfully doped into the ZnS cubic *** spectra have analyzed the elemental presence in the samples and it is evident that the spectra confirmed the presence of cobalt(Co),zinc(Zn),oxygen(O),and sulphur(S)elements only and no other impurities are *** ZnS-based quantum dot sensors reveal high sensitivity towards 50 ppm of ammonia vapors at an operating temperature of 70℃.Hence,ZnS-based quantum dots can be a promising and quick traceable sensor towards ammonia sensing applications with good response and recovery time.

关键词： ZnS co-precipitation cobalt doped ZnS XRD quantum dots gas sensor ammonia response

Iridium Implantation in T1 and T2 Cancers of Anterior Tongue: Report from B. P. koirala Memorial Cancer Hospital, Nepal

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2012年第3期1卷 73-77页

作者： vijayakumar Narayanan Bibek Acharya Chaurasia Pradumna Prasad Dejkumar Gautam Clinical Director Cancer Care Kenya Nairobi Kenya Department of Otorhinolaryngology B. P. Koirala Memorial Cancer Hospital Bharatpur Nepal Department of Radiation Oncology B. P. Koirala Memorial Cancer Hospital Bharatpur Nepal

Early stage cancers of tongue are treated traditionally with a wide local excision or hemiglossectomy, but the preservation of normal speech and swallowing are hampered. Most of the patients are treated with external beam irradiation to achieve the best locoregional control as only a limited number of tongue cancers can be excised. Underdeveloped nations with finite resources are still dependent on cobalt based external beam radiotherapy and sometimes a Linear Accelerator with two dimensional planning. This treatment has many limitations, as the large radiation fields irradiate not only the tumor but also normal tissue. The sequalae include mucositis, dry mouth, teeth and gum injury, spinal cord damage and rarely mandibular necrosis. Intensity modulated radiotherapy, which can abrogate these side effects, is not available to these patients. Irradiation using implanted solid radioactive sources into the tumor tissue is a viable option in this context. This kind of treatment is termed as brachytherapy and if the implant is introduced into the tissue then it is interstitial brachytherapy. This report details our experience in interstitial implantation, planning, dosimetry and treatment. Diagnosed cancers of anterior 2/3rd of lateral border of tongue with T1 N0M0 or T2 N0M0 stages were subjected to Iridium implantation under general anesthesia. Orthogonal films were taken and planning done with brachyvision treatment planning system. High dose rate radiotherapy was delivered as per the prescription. Excellent local control of the tumor was achieved with no undue morbidity to the adjacent structures. The patients were asked to undergo regular follow up. Surgical salvage was advised in cases of nodal recurrence. Interstitial implantation is a treatment that can be safely administered in early stage cancers of the tongue. This has remarkable efficacy and is also a patient friendly procedure.

关键词： Oral Cavity Cancer Interstitial Brachytherapy Implantation Remote After loader