检索结果-南通市图书馆

Hypoxia inducible factor-1αaccumulation in steatotic liver preservation:Role of nitric oxide

World Journal of Gastroenterology 2010年第28期16卷 3499-3509页

作者： Mohamed Amine Zaouali Ismail Ben Mosbah Eleonora Boncompagni Hassen Ben Abdennebi Maria Teresa Mitjavila Ramon Bartrons Isabel freitas Antoni Rimola Joan Roselló-Catafau Experimental Hepatic Ischemia Reperfusion Unit Institut of Biomedical Research of BarcelonaSpanish National Research Council08036BarcelonaSpain Liver Transplantation and Graft Viability Unit August Pi i Sunyer Biomedical Research Institut08036Barcelona Spain Animal Biology Department Pavia University27100PaviaItaly Laboratory of Human Physiology Faculty of PharmacyUniversity of Monastir5000Monastir Tunisia Department of Physiology Faculty of BiologyUniversity of Barcelona08028BarcelonaSpain Physiological Sciences Department Bellvitge CampusInstitut of Biomedical Research of Bellvitge-Barcelona University08907BarcelonaSpain

AIM:To examine the relevance of hypoxia inducible factor(HIF-1)and nitric oxide(NO)on the preservation of fatty liver against cold ischemia-reperfusion injury(IRI). METHODS:We used an isolated perfused rat liver model and we evaluated HIF-1αin steatotic and non-steatotic livers preserved for 24 h at 4℃in University of Wisconsin and IGL-1 solutions,and then subjected to 2 h of normothermic *** normoxic reperfusion,liver enzymes,bile production,bromosulfophthalein clearance,as well as HIF-1αand NO[endothelial NO synthase(eNOS)activity and nitrites/nitrates]were also *** factors associated with the higher susceptibility of steatotic livers to IRI,such as mitochondrial damage and vascular resistance were evaluated. RESULTS:A significant increase in HIF-1αwas found in steatotic and non-steatotic livers preserved in IGL-1 after cold *** preserved in IGL-1 showed a significant attenuation of liver injury and improvement in liver function *** benefits were enhanced by the addition of trimetazidine(an antiischemic drug),which induces NO and eNOS activation, to IGL-1 *** normoxic reperfusion,the presence of NO favors HIF-1αaccumulation,promoting also the activation of other cytoprotective genes,such as hemeoxygenase-1. CONCLUSION:We found evidence for the role of the HIF-1α/NO system in fatty liver preservation,especially when IGL-1 solution is used.

关键词： Fatty liver Tissue preservation Hypoxia inducible factor-1α IGL-1 Nitric oxide Trimetazidine

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

二维导流管喷动床的流动特征

引用

化工冶金 2000年第4期21卷 369-374页

作者：罗保林 freitas L A P Lim C J Grace J R 中国科学院化工冶金研究所北京100080 加拿大不列颠哥伦比亚大学化工系

带导流管的二维喷动床(2-DSBDP)是传统喷动床的改进型式，矩形床内设置的与床同厚的垂直导流管可以控制固体颗粒的循环速率, 同时使下行区中的气固移动床维持平推流. 本文实验测定了不同表观气速、床层高度、固体颗粒与气体入口尺寸时,... 详细信息

带导流管的二维喷动床(2-DSBDP)是传统喷动床的改进型式，矩形床内设置的与床同厚的垂直导流管可以控制固体颗粒的循环速率, 同时使下行区中的气固移动床维持平推流. 本文实验测定了不同表观气速、床层高度、固体颗粒与气体入口尺寸时, 二维导流管喷动床的床压降及相应的空隙率，藉以阐述2-DSBDP的流动特征.

关键词：二维喷动床导流管流动特征

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

未来的燃料需要更“多油”的大豆

引用

商业周刊（中文版） 2023年第21期 35-36页

作者： Gerson freitas Jr. Michael Hirtzer 融汐(译) 不详

●可再生燃料需求飙升,转基因大豆生产的燃料可以帮助降低飞机和卡车的排放,但在美国广泛采用仍需时间为了减少客机和长途卡车的碳排放,我们将需要大量以大豆为基础的可再生燃料。为了生产它,美国农民可能要把现有的所有玉米地夷为平地... 详细信息

●可再生燃料需求飙升,转基因大豆生产的燃料可以帮助降低飞机和卡车的排放,但在美国广泛采用仍需时间为了减少客机和长途卡车的碳排放,我们将需要大量以大豆为基础的可再生燃料。为了生产它,美国农民可能要把现有的所有玉米地夷为平地,种植数百万亩的大豆,并停止所有大豆出口。

关键词：可再生燃料转基因大豆玉米地碳排放大豆出口卡车农民

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Delivery of essential pediatric congenital surgical care within Brazil’s universal health coverage system:a national survey of pediatric surgeons

引用

World Journal of Pediatric Surgery 2023年第3期6卷 136-146页

作者： Paul R Truche Abbie E Naus Fabio Botelho Julia Ferreira Alexis Bowder Luke Caddell kathrin Zimmerman Isabella Maria de freitas Faria Bellisa Caldas Lopes Eduardo Corrêa Costa Fernanda Lage Lima Dantas Augusto J S A Cavalcante Carlos A L B Carvalho Simone Abib David P Mooney Nivaldo Alonso Program in Global Surgery and Social Change Harvard Medical SchoolBostonMassachusettsUSA Department of Surgery Rutgers Robert Wood Johnson Medical SchoolNew BrunswickNew JerseyUSA Department of Pediatric Surgery McGill UniversityMontrealQuébecCanada Department of Surgery Medical College of WisconsinMilwaukeeWisconsinUSA Division of Otolaryngology-Head and Neck Surgery Department of SurgeryUniversity of Wisconsin-Madison School of Medicine and Public HealthMadisonWisconsinUSA School of Medicine UFMGBelo HorizonteMinas GeraisBrazil Department of Pediatric Surgery Instituto de Medicina Integral Professor Fernando FigueiraRecifeBrazil Department of Pediatric Surgery Hospital de Clinicas de Porto AlegrePorto AlegreBrazil Department of Pediatric Surgery Federal University of AcreRio BrancoBrazil Department of Pediatric Surgery Hospital Santa Casa de Belo HorizonteBelo HorizonteBrazil Department of Pediatric Surgery Federal University of Mato GrossoCuiabaBrazil Department of Pediatric Surgery UNIFESPSao PauloBrazil Department of Pediatric Surgery Boston Children's HospitalBostonMassachusettsUSA Department of Plastic Surgery University of São Paulo Institute of Biomedical SciencesSao PauloBrazil

Objective In this study,we assess the delivery of congenital pediatric surgical care under Brazil’s system of universal health coverage and evaluate differences in delivery between public and private *** A cross-sectional national survey of pediatric surgeons in Brazil was *** were asked which of 23 interventions identified through the Disease Control Priorities 3(Surgical Interventions for Congenital Anomalies)they perform and to report barriers faced while providing surgical *** were weighted by state and stratified by sector(public vs private).Results A sample of 352 responses was obtained and weighted to represent 1378 practicing pediatric surgeons registered in Brazil during the survey time.73%spend the majority of their time working in the public sector(‘SistemaÚnico de Saúde’and Foundation hospitals),and most of them also work in the private ***,Brazilian pediatric surgeons have the expertise to provide thoracic,abdominal,and urologic *** working mostly in the public sector were more likely to report a lack of access to essential medications(25%vs 9%,pk of access to hospital beds for surgical patients(52%vs 32%,pking in government-financed hospitals face barriers related to infrastructure,which may impact Brazilians who rely on Brazil’s universal health coverage *** that support pediatric surgeons working in the public sector may promote the workforce available to provide congenital pediatric surgical care.

关键词： pediatric survey Brazil

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Case Report of Right Pneumonectomy with a Focus on the Right Ventricular Function and Hemodynamic Management

引用

Open Journal of Anesthesiology 2022年第10期12卷 315-321页

作者： Maria Júlia Spini Logato Lorena Machado Marques Faria Gabriela Veloso de freitas Clayton Gil de Castro Francisco Biagio Murtae Di Flora Marina Ayres Delgado Hospital das clínicas de Belo Horizonte Universidade Federal de Minas Gerais Belo Horizonte Brazil

Background: In patients undergoing pneumonectomy, intraoperative pulmonary and cardiac complications are the major cause of morbidity and mortality. Protective lung ventilation strategies may decrease the overall lung injury. Right, ventricular dysfunction may occur during the surgery and after the pneumonectomy, in the early postoperative period, with reduced RV ejection fraction and increased RV end-diastolic volume index, caused by increased RV afterload. Case report: We describe the case of a 28-year-old non-smoker female who underwent to a right pneumonectomy. The patient presented intraoperative hemodynamic instability and signs of RV dysfunction, requiring vasoactive amines and nitric oxide. Discussion: This article is intended to provide an overview of the anesthetic management for pneumonectomy including the hemodynamic management and considerations of the causes and management of right ventricular dysfunction.

关键词： Anesthesia Lung Resection Surgery Nitric Acid Pneumonectomy Right Ventricular Dysfunction Thoracic Surgery

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Imaging evaluation of the liver in oncology patients:A comparison of techniques

引用

World Journal of Hepatology 2021年第12期13卷 1936-1955页

作者： Patrícia S freitas Catarina Janicas JoséVeiga António P Matos Vasco Herédia Miguel Ramalho Department of Radiology Centro Hospitalar Universitário de Lisboa CentralLisbon 1150-199Portugal Department of Radiology Centro Hospitalar de Lisboa OcidentalLisbon 1449-005Portugal Department of Radiology Hospital Garcia de OrtaEPEAlmada 2805-267Portugal Department of Radiology Hospital CUF TejoLisbon 1350-352Portugal Department of Radiology Hospital Espírito Santo deÉvora-EPEÉvora 7000-811Portugal Department of Radiology Hospital da LuzLisbon 1500-650Portugal

The liver is commonly affected by metastatic ***,it is essential to detect and characterize liver metastases,assuming that patient management and prognosis rely on *** imaging techniques that allow non-invasive assessment of liver metastases include ultrasonography,computed tomography(CT),magnetic resonance imaging(MRI),positron emission tomography(PET)/CT,and PET/*** this paper,we review the imaging findings of liver metastases,focusing on each imaging modality’s advantages and potential *** also assess the importance of different imaging modalities for the management,follow-up,and therapy response of liver *** date,both CT and MRI are the most appropriate imaging methods for initial lesion detection,follow-up,and assessment of treatment *** MRI is frequently used as a problem-solving technique for liver lesions and has evolved substantially over the past decade,including hardware and software developments and specific intravenous contrast *** studies have shown that MRI performs better in small-sized metastases and moderate to severe liver steatosis *** state-of-the-art MRI shows a greater sensitivity for detecting and characterizing liver metastases,CT remains the chosen *** also present the controversial subject of the"economic implication"to use CT over MRI.

关键词： Liver metastases Magnetic resonance imaging Computed tomography Oncology Ultrasound Follow-up

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The growth and production modeling of individual trees of Eucalyptus urophylla plantations

引用

Journal of Forestry Research 2020年第5期31卷 1663-1672页

作者： Joao Victor Nobre Carrijo Ana Beatriz de freitas Ferreira Marcela Costa Ferreira Mario Cesar de Aguiar Eder Pereira Miguel Eraldo Aparecido Trondoli Matricardi Alba Valeria Rezende Department of Forestry Faculty of TechnologyUniversity of Brası´liaBrası´lia 70910-900Brazil

Individual tree models(ITMs)are classified as growth and production models for projecting current and future forest *** are more complex than other growth and production models,show a higher level of detail and,consequently,produce a better modeling ***,the accuracy and efficiency of ITMs have not been properly assessed to *** this study,we estimated the growth in height,diameter,and individual tree volume of a Eucalyptus urophylla plantation by applying an *** used a continuing forest inventory dataset in which 1554 individual trees within 29 permanent plots were measured in the field over a 6-year period(24 to 72 months).Each individual tree volume was estimated for future tree *** achieve this,we adjusted the model to predict the height and diameter growth,and the probability of mortality as a function of the competition *** ITM accuracy was assessed based on the analysis of variance results and,subsequently,the multiple mean comparison test at the 5%significance *** tree volumes predicted by the ITM for the forest stand aged 72 months,beginning at ages 24,36,48,and 60 months,were compared to the field measured tree volume acquired from the 72-month forest inventory that was used as the reference *** and observed tree volumes were similar when the estimation was based on the 48-month forest *** results might help to reduce financial costs of forest inventory because the ITM produces accurate future predictions of forest stand *** estimated ITM for Eucalyptus plantations using measurement intervals up to 2 years is recommended because it significantly reduced the projected volume discrepancy compared to the field measurements.

关键词： Competition index Forest production Forest site Simulation models Tree mortality

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Hepatocellular carcinoma staging systems: Hong kong liver cancer vs Barcelona clinic liver cancer in a Western population

引用

World Journal of Hepatology 2019年第9期11卷 678-688页

作者： Laura Bainy Rodrigues de freitas Larisse Longo Deivid Santos Ivana Grivicich Mário Reis Alvares-da-Silva Graduate Program in Gastroenterology and Hepatology Universidade Federal do Rio Grande do SulPorto AlegreRS 90035-003Brazil Experimental Hepatology and Gastroenterology Laboratory Center for Experimental ResearchHospital de Clínicas de Porto AlegrePorto AlegreRS 90035-003Brazil School of Medicine Universidade Federal do Rio Grande do SulPorto AlegreRS 90035-003Brazil Graduate Program in Health-Applied Cellular and Molecular Biology ULBRA.CanoasRS 92425-900Brazil Department of Gastroenterology Hospital de Clínicas de Porto AlegrePorto AlegreRS 90035-003Brazil

BACkGROUND Despite being the world’s most widely used system for staging and therapeutic guidance in hepatocellular carcinoma(HCC)treatment,the Barcelona clinic liver cancer(BCLC)system has limitations,especially regarding intermediate-grade(BCLC-B)*** recently proposed Hong kong liver cancer(HkLC)staging system appears useful but requires validation in Western *** To evaluate the agreement between BCLC and HkLC staging on the management of HCC in a Western population,estimating the overall patient *** This was a retrospective study of HCC patients treated at a university hospital in southern Brazil between 2011 and ***,clinical,and laboratory data were *** staging was carried out according to the HkLC and BCLC systems to assess treatment *** survival was estimated based on the treatment proposed in each *** A total of 519 HCC patients were *** these,178(34.3%)were HkLC-I;95(18.3%)HkLC-IIA;47(9.1%)HkLC-IIB;29(5.6%)HkLC-IIIA;30(5.8%)HkLCIIIB;75(14.4%)HkLC-IV;and 65(12.5%)*** to the BCLC,25(4.9%)were BCLC-0;246(47.4%)BCLC-A;107(20.6%)BCLC-B;76(14.6%)BCLCC;and 65(12.5%)*** general agreement between the two systems was 80.0%-BCLC-0 and HkLC-I(100%);BCLC-A and HkLC-I/HkLC-II(96.7%);BCLC-B and HkLC-III(46.7%);BCLC-C and HkLC-IV(98.7%);BCLC-D and HkLC-V(41.5%).When sub-classifying BCLC-A,HkLC-IIB,HkLC-IIIA and HkLC-IIIB stages according to the up-to-7 in/out criterion,13.4,66.0,100 and 36.7%,respectively,of the cases were classified as up-to-7 *** In a Western population,the general agreement between the two systems was 80.0%,although in BCLC-B cases the agreement was low,suggesting that some individuals could be candidates for the curative treatment recommended by the *** authors suggest that the BCLC system should be routinely employed,although for BCLC-B cases it should be associated with the HkLC system.

关键词： Barcelona clinic liver cancer staging system Hepatocellular carcinoma Hong kong liver cancer staging system

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Commodities Boom and the Structure of Sino-Brazilian Trade: A Study of the Period 2000-2021

引用

Chinese Business Review 2023年第2期22卷 61-68页

作者： Higor de freitas University of Campinas CampinasBrazil

The present study aims to analyze the growing Sino-Brazilian trade relationship and how China has contributed to the commodity price boom in the recent *** the article,it was possible to identify that the export and import agenda between countries differs in terms of number of products and technological intensity,so that imported products are capital intensive,while exported products are predominantly *** text is divided into two main sections,firstly addressing the literature review on the commodities boom and highlighting the“China effect”.The second section analyzes trade between the countries,so that the trade relationship has followed an increasing trajectory since *** of 2009,China has become Brazil’s main trading partner,surpassing historical partners such as the United States and Argentina.

关键词： trade balance commodities Brazil-China trade structure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

时过境迁美国粮食外交威力不再

引用

商业周刊（中文版） 2023年第18期 30-31页

作者： Isis Almeida Gerson freitas Jr. Michael Hirtzer 晴川(译) 不详

1957年,国际贸易博览会空降到萨格勒布举办,会上最令人惊牙的大热门不是乘坐直升机或参观机械展,而是一个按照真实比例和功能复制还原的美国超市。这个超市是美国展馆的核心展览,一排排新搭建的货架上摆满了新鲜的水果、蔬菜和肉类,这... 详细信息

1957年,国际贸易博览会空降到萨格勒布举办,会上最令人惊牙的大热门不是乘坐直升机或参观机械展,而是一个按照真实比例和功能复制还原的美国超市。这个超市是美国展馆的核心展览,一排排新搭建的货架上摆满了新鲜的水果、蔬菜和肉类,这一切让来自当时还属于南斯拉夫的这个城市的一些参观者惊叹不已。

关键词：机械展超市粮食外交南斯拉夫参观者

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：